Response of Myostatin to Resistance Exercise with and without Blood Flow Restriction in Immature Male Athletes

Resistance training is the most effective way known to increase muscle mass. Myostatin is one of the factors involved in the control of muscle mass. The purpose of this study was to compare two types to resistance training with and without blood flow restriction on Myostatin after the exercise. For this purpose, 36 adolescent gymnast boys aged 10 to 14 years participated in a quasi-experimental research design. The subjects (mean weight 37.11±8.11 kg, height 145.16±11.58 cm, body mass index 17.40±1.77 kg/m2) were randomly divided into three equal groups (n=12); control (30% 1RM), high intensity resistance training (75% 1RM), and low intensity resistance training with blood flow restriction (30% 1RM). Training protocol includes three motions included leg extension, elbow flexion and bench press. Blood samples were taken before and half an hour after training. Using T-dependent test to check the results of intergroup and One-Way ANOVA with LSD test was used for evaluating the results of between groups. The results of inter-group showed in blood flow restriction group (p=0.028) was significant, but in control (p=0.553) and high intensity resistance groups (p=0.257), was not significant. The results showed that in both of them protocol, there was no significant difference between groups in levels of Myostatin (p=0.683).One session Resistance exercise with blood flow restriction compared to high intensity resistance exercise, a similar effect in increasing serum Myostatin children athletes and for this reason, such as high intensity resistance exercise seems appropriate to provide Myostatin inhibition and increased muscle mass.