Simultaneous Electroanalysis of Norepinephrine, Ascorbic Acid and Uric Acid at Poly(niacinamide) Modified Carbon Paste Electrode

Niacinamide was electropolymerised on the surface of carbon paste electrode by cyclic voltammetric technique. The modified electrode showed an excellent electrocatalytic activity towards the oxidation of norepinephrine (NE) and ascorbic acid (AA). The response of the sensor was evaluated towards the different NE concentration in the range 40.98 to 244.3 µM, the oxidation peak current was linearly increased with varying NE concentration and the detection limit was calculated to be 0.21 µM. The modified electrode showed excellent selectivity in the determination of NE in presence of large excess of AA and UA. The voltammetric responses were stable and resistant to fouling. The proposed electrode can be used for the real sample analysis in medical, pharmaceutical and biotechnological sectors.