An Electrochemical Sensor for the Determination of 5-Amino Salicylic Acid at Poly (alanine) Modified Carbon Paste Electrode: A Cyclic Voltammetric Study

Poly (alanine) modified carbon paste electrode (CPE) was fabricated for the determination of 5-amino salicylic acid (5-ASA) by cyclic voltammetric technique. The poly (alanine) modified CPE exhibited a high sensitivity towards the oxidation of 5-ASA. The effect of scan rate was found to be surface-controlled diffusion process and the concentration study was conducted between the range of 20-180 µM. The limit of detection (3 S/M) and limit of quantification (10 S/M) were calculated and found to be 0.23 µM and 0.76 µM respectively. Because of high sensitivity in the electro-oxidation, the fabricated poly (alanine) modified CPE can be used as a promising electrochemical sensor for the determination of 5-ASA in both commercial as well as in pharmaceutical samples.