CHANGES IN CHEMERIN SERUM LEVEL AND INSULIN RESISTANCE INDEX IN ELDERLY MEN AFTER EIGHT WEEKS COMBINED TRAINING (AEROBIC-RESISTANCE)

Chemerin is one of the adipocines that is secreted in the form of prochemerin from visceral fat, liver, adipose tissue, aorta and coronary artery wall, and can be considered as a predictor of cardiovascular disease particularly in elderly men. This study was carried out to evaluate the effect of eight weeks of endurance and resistance training on chemerin level, insulin resistance index in inactive elderly men. In this quasi-experimental study, 24 inactive elderly men were non-randomly divided into interventional and control groups. The combined training included endurance training (with intensity of 60-70% of maximum heart rate reserve) and resistance training (with intensity of 70% one repetition maximum). The training was performed three times per week (one hour session) for 8 weeks. Chemerin, glucose, insulin and insulin resistance index were measured in two groups before and after eight weeks. The eight weeks of combined training decreased the chemerin level, insulin and FBS levels, insulin resistance index, and body fat percentage in interventional group compared to the controls (P<0.05). The eight weeks of combined training decreased the chemerin level and insulin resistance in elderly men.