Effect of coenzyme Q10 consumption before one session of resistance exercise on serum AST and Delayed Onset Muscle Soreness in male college athletes

Consumption of anti-oxidant supplement decrease oxidative stress due to intensive exercise. The aim of this study was to investigate the effect of acute supplementary consumption of coenzyme Q10 on serum aspartate aminotransferase (AST) and Delayed Onset Muscle Soreness (DOMS) after a session of resistance exercise in male college athletes. eighteen male college athletes (age: 21.1±1.2 yr, weight: 72.5 ± 8.1 kg, height: 177.4 ± 7.3 cm, body mass index: 23.2 ± 2.1 kg/m2) with at least 6 months of regular exercise training, divided into Q10 supplement and placebo groups randomly. 120 minutes before exercise, subjects received either of the following regimens: Coenzyme Q10 (200 mg per subject) or placebo (Flour). All subjects underwent a circuit resistance exercise include 5 stations that performed in 3 sets with 75% of 1RM. AST concentration was measured before supplementation and immediately, 24, 48 hours after the exercise. DOMS, in addition of these times, were assessed within 72 hours after exercise. Data were analyzed by ANOVA with repeated measure, Bonferroni and independent t test at P≤0.05. The results shown that change in AST was not significantly different between two groups (Р=0.072). But changes in DOMS between the two groups was significant (Р=0.032). Based on the results, it seems that acute Q10 supplements can reduce DOMS (fatigue index) and serum AST (index of cellular damage) in male college athletes after resistance exercise.