The effect of 12 weeks of aerobic exercise on NT-proBNP in women with hypertension

N-terminal proBNP (NTproBNP) is widely used as a diagnostic biomarker and for the risk stratification of patients with heart failure (HF). Its role in the evaluation of patients with hypertension is not completely clear. The purpose of this study was to investigate the effect of 12 weeks of aerobic exercise on NT-pro BNP in women with hypertension.

Thirty-five middle-aged women with hypertension were randomly divided into two groups of the aerobic training and the control. The aerobic exercise group completed 12 weeks of exercise, 3 sessions per weak, with 35-60% of the maximum heart rate. Serum NT-proBNP marker was determined by Elecsys method, and 5 ml of blood was collected from brachial veins.

The results demonstrated that 12 weeks of aerobic training had a positive and significant effect on NT-pro BNP concentration in patients with hypertension (p <0.05)

Overall, it seems that 12 weeks of aerobic exercise has been beneficial in patients with hypertension, and has improved myocardial function. However, this issue requires further research.