Effect of eight weeks aerobic training on nitric oxide and apelin levels in women with pre-hypertension

Blood pressure is affected by various factors including activity. The aim of this study was to investigate the effect of eight weeks of aerobic training on blood pressure, nitric oxide and apelin in women with pre-hypertension.

Twenty-four women aged 30-45 years with pre-hypertension were randomly divided in two groups: aerobic and control. Aerobic exercise was performed three times a week for eight weeks, This means that subjects the first week for 30 minutes at 50% heart rate reserve, the second and third weeks respectively were 35 and 40 minutes with a 50% intensity, Fourth week 40 minutes and intensity 55%, and 5th, 6th, 7th and 8th weeks run For a period 45 minutes with 55% heart rate reserve. Blood pressure measurement and blood sampling were performed one day before the first and 48 hours after the last exercise. Apelin and nitric oxide levels were measured using commercial kits by ELISA method. Statistical analysis of data was performed using independent and dependent t-test at a significant level (p <0.05).

After 8 weeks of aerobic activity, the levels of apelin and nitric oxide increased significantly in the training group (p <0.05). If the blood pressure level decreased significantly (p <0.05).

8 weeks of aerobic training can be beneficial for people with pre- hypertension by increasing nitric oxide and apelin levels and lowering blood pressure.