Homotaurine of marine macroalgae of the Persian Gulf as a potential treatment agent for Alzheimer

In this research, 3-aminopropanesulfonic acid, homotaurine, was determined in some Iranian species of green, red and brown macro algae for the first time. Ethanolic extractions of 10 marine green, red and brown algae species were investigated for the presence of homotaurine by high performance liquid chromatography- fluorescence detection. The analyte was derivatized with fluorescamine during a fast reaction at an ambient temperature and alkaline medium. The amounts of homotaurine detected in the marine algae species varied from 0.023 to 14.62 µg g-1 dry weight. Dictyota dichotoma, a brown macro alga, showed the highest amount of the studied bioactive compound. Good recovery (>83%) was also acquired by the used method for extraction of homotaurine from algae matrices.