A retrospective microbiologic study on admitted patients with diabetic foot infection in Razi teaching hospital in Ahvaz during 2015 –2019

One of the most common infectious diseases in diabetes mellitus is diabetic foot ulcer infection. This study was designed to identify the microorganisms that cause diabetic foot ulcer infection and their antibiotic resistance to improve the rational administration of antibiotics in experimental therapy.

The present descriptive cross-sectional study is retrospective. This study was performed on 200 patients admitted with a diagnosis of diabetic foot ulcer infection in the infectious ward of Razi Hospital in Ahvaz during the years 1394 to 1397. Finally, 126 of them were included in the study. Statistical analyzes were performed using SPSS software (v22) (IBM, USA).

In this study, 61 cases were female (48.4%), and 65 were male (51.6%). 18 cases (14.3%) were PEDIS 2, 71 cases (56.3%) were PEDIS 3, 37 cases (29.4%) were PEDIS 4. In this study, gram-negative bacteria 50.3% and gram-positive bacteria 49.7% were the cause of infection, and the three main strains were Staphylococcus aureus (41.3%), Escherichia coli (27.8%), and Staphylococcus epidermis (24.6%). 9.6% of Staphylococcus aureus were resistant to methicillin, and 5.7% of Escherichia coli were punk resistant. The lowest resistance was observed in gram-negative and positive bacteria to Meropenem and imipenem and the highest resistance to ciprofloxacin and clindamycin antibiotics.

it is necessary to study the causative strains and their antibiotic resistance alternately in each region. Progressive resistance to clindamycin and ciprofloxacin also reduces the effectiveness of these drugs in experimental therapies.