The Association between Physical Activity and Sperm Quality Parameters: A Cross-Sectional Study in Iranian Infertile Men

Infertility is described as inability of a couple to bring a child within 12 months or more of regular unprotected intercourse. Studies have suggested associations between semen quality and lifestyle factors, including physical activity and dietary intakes. This cross-sectional study aimed to assess the relationship between physical activity and sperm quality parameters in infertile men who referred to infertility clinic of Isfahan City, Iran, in 2019.

In this cross-sectional study, 175 infertile men (18-55 years old) who referred to Royan infertility clinic in Isfahan, entered the study after completing the written consent form. Demographic data were collected using a questionnaire and physical activity information was collected by International Physical Activity Questionnaire (IPAQ). Sperm quality parameters including sperm concentration (SC), total sperm motility (TSM), normal sperm morphology (NSM), and sperm volume were investigated by spermogram test. For all analyses, SPSS software was used and P ˂ 0.05 was considered as significance level.

Due to the lack of dissemination of physical activity data, all subjects were classified in the group of physical activity with moderate intensity. Multivariate logistic regression [odds ratio (OR)] with 95% confidence interval (CI) was used to assess more accurately the relationship between physical activity and abnormal sperm parameters. Median values of metabolic equivalent of task (METs) were used to analyze the data due to lack of dissemination of physical activity data and no significant relationship was observed between sperm quality parameters and levels above median compared to the reference level (levels below median) in participants.

No significant relationship was found between sperm quality parameters and physical activity pattern in infertile men. Furthermore, no relationship was found between body mass index (BMI) and sperm quality parameters.