Green Synthesis of Ag/Fe3O4 Nanocomposite by Aqueous Extract of Eryn-gium Caucasicum and Evaluation of its’ Antifungal Activity

The green nanoparticle synthesis method using plants due to a cost effective and environmental compatibility has been extensively noticed. In this study, the biosynthesis of Ag/Fe3O4 nanocomposite by using extract of Eryngium caucasicum and its antifungal properties has been reported.

Synthesized Ag/Fe3O4 nanocomposite was characterized by using UV-Visible spectroscopy, XRD, and FESEM analyses. The antifungal potential of Ag/Fe3O4 nanocomposite was evaluated using Disc diffusion assay.

The formation of Ag/Fe3O4 nanocomposite has confirmed through UV–visible spectroscopy (at 425 nm). XRD results revealed the crystalline nature of Ag/Fe3O4 nanocomposite and FESEM analysis exhibited spherical shape with size 26-42 nm. It was also detected that the Ag/Fe3O4 nanocomposite at a concentration of 150μg/ml had the highest inhibition on Cryptococcus neoformans compared to Fusarium thapsinum, Candida albicans, Pyricularia oryzae, Fusarium semitectum and Candida glabrata.

The results of this study showed that the Green synthesis of Ag/Fe3O4 nanocomposite by aqueous extract of Eryngium caucasicum, which is a new, non-toxic, simple, cost-effective, fast and environmentally friendly technique, have high antifungal activity.