The effect of eight weeks aerobic training and omega3 ingestion on the levels of CTRP-9 and adiponectin in overweight and obese women

Adiponectin and CTRP-9 are adipose tissue secreted adipokines mediating various tissue functions.

The present study aimed to investigate the effect of eight weeks aerobic training and Omega3 ingestion on the levels of CTRP-9 and adiponectin in women living with overweight and obesity.

Forty women age ranging 20-35 years old (average age of 27.29±3.27 years old, average body mass index (BMI): 29.6±1.93 kg.m2) participated in the present study voluntarily. Participants randomly assigned into four groups (10 persons in each group) including placebo, Omega3, training and training+Omega3 groups. The aerobic training program included eight weeks period (three sessions per week), and the Omega3 and Omega3+training groups consumed 2,000 mg of Omega3 supplements daily. Blood samples were collected pre and post intervention (48 hours after the last training session or Omega3 consumption), and adiponectin, CTRP-9 and insulin levels were measured by ELISA method. Data analysis was performed using analysis of covariance and Bonferroni post hoc test.

Significant decrease of CTRP-9 levels and insulin resistance, as well as a significant increase in adiponectin levels in the training and training+Omega3 groups compared to placebo and Omega3 groups were observed (p<0.05).

Based on our findings, it seems that positive effects of aerobic training alone or combined with Omega3 supplementation are partially exerted by increased and decreased adiponectin and CTRP-9 levels respectively, and Omega3 supplementation can increase the effectiveness of aerobic training in modulating CTRP-9 and adiponectin levels.