The prevalence of cleft lip or palate in infants born in Tehran Mahdieh Centre during 1370 - 1379

Cleft of lip and palate is the mostly reported congenital deformity in maxillofacial region. In spite of this, there is no comprehensive published study in the country. So, this study was conducted in order to evaluate the prevalence of cleft lip or cleft palate in infants born in Tehran Mahdieh Centre during the years between 1370 and 1379. Method & Materiasl: The study was carried out descriptively and analitically on existing data. The study included infants’ files born with cleft lip or palate (or both) in Tehran Mahdieh Centre during 1370 till 1379. The prevalence of cleft lip and palate, the mother's age, the mother gravity and blood group were studied. A total number of 87838 files were studied, of which, 131 infants were born with the mentioned deformities. 63 cases were females and 68 cases were males. The prevalence of cleft lip, cleft palate and both were 31.8%, 25% and 43.2% respectively. Cleft lip and cleft palate together was observed moslty in males while cleft palate had the same incidence in females. 24.2% of infants had anomalies other than cleft lip and palate. Familial relationship was noted in 28% of cases. The age of infant's mothers was 25.6±6.6 years. The most observed mother gravity was first gravity which were about 35.1%. The overall prevalence of cleft palate in the studied centre was 1.49 in 1000. The incidence rate was almost the same in both sexes. The incidence of lip and cleft palate together was more than lip and cleft palate separately. 77.1% of the infants had normal pregnancy period. Gravity of deformed infants’ mothers was 2.9±2 and the blood group of O was the most observed blood group in mothers.