Experimental and Insilico Studies on Anti-Microbial Activity of 𝑃. 𝑁𝑖𝑔𝑟𝑒𝑠𝑐𝑒𝑛𝑠 Leaves

The study was aimed at assessing the phytochemical composition and antibacterial efficacy of Parquetina nigrescens leaves against particular pathogenic microorganisms. In this work, N-Hexane, chloroform, and methanol were used to extract the Parquetina nigrescens. The phytochemical components of the extracts were examined and investigations into the extracts' antibacterial effects against S. pneumoniae, A. baumanii, P. areuginosa, and E. coli were also conducted. The results of the phytochemical examination showed that the extracts included possess various amounts of saponins, tannins, flavonoids, anthraquinones, and alkaloids. As a result of the presence of many phytochemicals, the results of the phytochemical screening suggested that P. nigrescens may have various biological applications. Parquetina nigrescens may be a powerful antibacterial agent, according to the findings of the antimicrobial activities. In addition, the antimicrobial susceptibility test (AST) revealed that Parquetina nigrescens extracts had high potentials in comparison to the control. Moreover, the results of this study suggested that Parquetina nigrescens may hold promise for the creation of effective pharmaceuticals.