Relationship between human chorionic gonadotrapin (HCG) level in second trimester pregnancy and preeclampsia

Many researches have shown a relationship between levels of βHCG in pregnancy and preeclampsia which can be used as a method for early diagnosis. The aim of this study was to determine relationship between levels of HCG in second trimester of pregnancy and preeclampsia. This study was conducted as a Nested case control study. Blood samples were taken from 1200 pregnant women who were in their second trimester of pregnancy and were admitted for prenatal care in Arak prenatal clinics. After isolation of serums blood samples were stored in -20◦C until delivery time. Finally serum HCG levels blood pressure proteinurea edema seizure and neonate statue were analyzed in 50 preeclamptic women (case group) and were compared with 50 normotensive women (control group). All women were complicated with mild preeclampsia. The mean of the βHCG in preeclamptic women was 43.08±32.56 Iu/ml and means of HCG in normotensive women was 27.48±25.97 mu/ml (P