نشریه مطالعات نوین در متابولیسم ورزش و فعالیت بدنی
پیاپی 2 (تابستان 1402)

Purpose of this study was to investigate effect of 12 weeks of aerobic training on serum level of ApoM, lipids profile and insulin resistance index in obese women.Twenty obese womenwere divided into experimental and control groups (10 ones in each) homogenized according to the body mass index. Subjects in experimental group participated in twelve weeks of aerobic running training at intensity of 50-75 percentage of reserve heart rate, 30-55 minutes per session and five sessions per week. Blood sampling was performed immediately before the first session and 48 hours after the last training session to assess blood factors. Statistical analysis was done by Covariance, paired t-test and Pearson correlation at significant level of P<0.05.According to covariance, there existed significant differences between two groups of experimental and control for changes in levels of ApoM insulin fasting glucose triglyceride cholesterol HDL and LDL insulin resistance index weight body fat percentage waist and hip circumferences. T-test findings showed 12 weeks of aerobic training resulted in significant decreases in levels of ApoM and HDL accompanied with significant decreases in levels of insulin fasting glucose triglyceride cholesterol and LDL insulin resistance index and anthropometric indices (P<0.05) in experimental group in post-test compared to pre-test. However, there were significant positive correlation between changes in serum levels of Apom following 12 weeks of aerobic training with changes in cholestrol levels.It seems that 12 weeks of aerobic training can improve body composition, lipid profile and insulin resistance, despite the deccreases in serum levels of ApoM.

An important part of cases related to sudden death and heart attack in the elderly can be attributed to obstruction of cerebral and coronary arteries due to thrombosis due to increased platelet count and activity. Therefore, the present study aimed to investigate the effect of eight weeks of endurance training on some blood coagulation indices were designed in elderly male Wistar rats.

This study was conducted as a post-test with two groups (endurance training and control). In this study, we tried to control all research variables. These variables include the same food and water, the same storage temperature and humidity (23±2 ° C and relative humidity of /055±5), the same sleep and light cycle (12:12), the same gender and health status), all male and female The main training program included running on a treadmill with increasing duration and following the principle of overload from 25 minutes to 54 minutes and changing the training speed from 15 to 20 meters per minute. This program lasted for 8 minutes. 5 sessions per week were performed per week, to warm up the animals at the beginning of each training session for 3 minutes at a speed of 7 meters per minute and then to reach the desired speed per minute, 2 meters per minute was added to the treadmill speed To cool the body at the end of each session, the speed was reduced inversely to reach the initial speed.

Nesfatin-1 and Apelin as two inflammatory adipocytokines affected by various stresses, including exercise. The purpose of this study was to investigate the effect of 14 days of resveratrol supplementation on changes in serum levels of Apelin and nesfatin-1 in response to one bout of exhaustive exercise in young sedentary overweight men.

20 young sedentary overweight men (mean aged= 35.7±3.26 years, BMI= 28.73±1.18 kg/m2) selected and randomly divided into two groups (experimental and control). Subjects in both experimental and control groups participated in one bout of exhaustive exercise (Bruce Test). Then, subjects in experimental group (supplementation) consumed one capsule of 400-mg resveratrol per day for 14 days. In control group (placebo), subject consumed one capsule of 400-mg lactose per day for 14 days. First blood sample was taken before the study and second one was done immediately after Bruce test. At the fifteenth day and at the end of 14 days of supplementation, subjects in both groups perform the exhaustive exercise again and forth blood sample was taken immediately following their performance. According to t-test, in the experimental group and following supplementation, changes in serum levels of Nesfatin-1 were significant in response to one bout of exhaustive exercise. However, following supplementation, there were significant differences between mean changes of Apelin levels in response to one bout of exhaustive exercise in experimental group compared to control group. According to Pearson correlation, there existed significant correlations between primary levels of Nesfatin-1 and primary values of body weight.

Angiogenesis improvement treatments are effective in reduction of stroke induced organ injury. The aim of this study was to investigate the effects of an endurance training with and without adenosine consumption on some angiogenic genes expression in hippocampus of male Wistar rats after ischemia reperfusion injury.

After induction of ischemia reperfusion injury, rats were divided into three groups of ischemia (group1), ischemia with exercise (group2) and ischemia with exercise and adenosine (group3). Exercise groups performed endurance trainings on treadmill for 8 weeks (5 sessions per week) with intensity of 30m per minute. Adenosine dosage in group3 was 0/4 mg per kg. Hippocampus of the rats were isolated for gene expression analysis after trainings.

There was difference between groups 1&3 and 2&3 in HIF1α gene expression (P=0/000); in case of HIF2α, all groups were different (P=0/000); R4 gene expression was different between groups 1&2 and 1&3 (P=0/004); S2 gene expression was different in all groups (P=0/000); HMGB1 gene expression was different between groups 1&2 (P=0/011), 1&3 (P=0/000) and 2&3 (P=0/000) and significant difference was observed in all groups in AP1 gene expression (P=0/000).

After ischemia reperfusion injury, eight weeks' endurance training may be effective in improvement of angiogenesis through elevation of HIF1α, HIF2α, S2, R4, HMGB1 and AP1 genes expression and this effect is reinforced by adenosine treatment.

Today, the use of potent drugs is very common among athletes, and steroid hormones are being used to improve exercise performance. The aim of the present study was to investigate the side effects of anabolic Boldenone steroid on pancreatic tissue and the healing effect of jujube extract with resistance training on reducing these complications.

42 wistar male rats, aged 8-12 weeks, and weights 180-220 grams were studied. After two weeks of maintenance and getting used to the training protocols, the third week of exercise began. Subjects were randomly divided into 6 groups of 7 (Boldenone group and resistance training, Boldenone, Boldenone and Jujube extract, Boldenone without resistance training, Control and Sham) and were evaluated for desirable results.

The results showed that changes in weight gain in the hormone training group were significant (P=0), but in exercise groups alone (P=1.000) and hormone alone (P=0974) and jujube hormones (P> 0.05 - P =0989) has not been meaningful. High-dose steroids have been responsible for the destruction of pancreatic axins, islets of Langerhans and blood vessels.

The results showed that the use of high-dose anabolic steroids results in the destruction of pancreatic tissue and exercise and jujube extracts can be effective in reducing the destructive effects of steroids.