International Journal of new Chemistry
Volume:11 Issue: 3, Autumn 2024

In this study, we have conducted a detailed analysis of 10 recently synthesized chromen derivatives to evaluate their performance as electrocatalytic sensing materials for the detection of Li+ ions. Our investigation involved the use of Infra-red (IR) and frontier molecular orbital (FMO) computations to gain insights into the interactions between these derivatives and Li+ ions. The results obtained from our analysis revealed that the derivative with NO2 substitution in the meta position of the benzene ring exhibited the strongest interaction with Li+ ions. This was observed in both vacuum and aqueous phases, with Kf values of 5.429×10+48 and 1.036×10+23, respectively. Such a strong interaction suggests that this derivative has the potential to be an excellent candidate for the development of electrochemical sensors for the detection of Li+ ions. Furthermore, we also investigated the changes in the bandgap of this derivative during the complexation process. Our findings indicated that this particular derivative experienced the most significant changes in its bandgap, with a percentage decrease of -50.824. This observation highlights its potential as a selective and sensitive recognition element for the detection of Li+ ions. Overall, our research provides valuable insights into the performance of these chromen derivatives as electrocatalytic sensing materials for Li+ ion detection. The derivative with NO2 substitution in the meta position of the benzene ring emerges as a promising candidate due to its strong interaction with Li+ ions and significant changes in its bandgap during complexation. These findings pave the way for the development of new and improved electrochemical sensors for the detection of Li+ ions, which can have significant implications in various fields such as energy storage and battery technologies.

In this investigation, the function of the smallest fullerene (C20) as a sensor and nano-carrier for the tricyclic antidepressant drug desipramine was scrutinized through density functional theory simulations. The achieved adsorption energies showed the interaction of desipramine with C20 is experimentally possible. The calculated ΔGad, ΔHad and Kth showed the adsorption process is spontaneous, exothermic and reversible. The influences of solvent and temperature on the interactions were also studied and the results showed the adsorption process is more favorable in lower temperatures and the presence of solvent does not have any effect on the nature of interactions. The NBO analysis showed no chemical bond has been created between desipramine and nanostructure and the existing interaction is a physisorption. The frontier molecular orbital analysis results showed the bandgap of fullerene decline -35.30% from 7.678 (eV) to 2.484 (eV) indicating this nanomaterial can be an ideal sensor for the detection of desipramine. The values of dipole moment and chemical hardness showed C20 can be employed as an appropriate nano-carrier for the drug delivery of desipramine.

A novel biopolymeric hydrogels have been synthesized by two step process using trans aconitic acid, ethylene glycol and glutamic acid without a cross linker by organic solventless approach with different monomer ratios in a eco friendly manner. The nature of bonding and structural identification of biopolymeri hydrogels were characterized by analytical techniques like FT-IR. The hydrogel shows a pH sensitive swelling behaviour with increased swelling in acidic media followed by gradual decreased in basic media. The thermogram (TGA) of the hydrogel shows two stage of degradation. The obtained hydrogels were also subjected to antibacterial activity against gram positive S.aureus and gram negative E.Coli by using zone inhibition method, and antioxidant activity by DPPH radical assay at different concentration compared with the standard Ascorbic acid and anticancer activity by MTT assay using HT29 colan cancer cell line. The results exhibit excellent antibacterial, antioxidant and anticancer property with respect to their standards respectively.

Manganese oxide (MnO) nanoparticles are essential materials in various applications such as sensors, catalysis, molecular adsorption, electronics, and exhibited excellent antimicrobial activity. Due to the numerous demerits of current nanoparticle synthetic approaches, there is a surge in the exploration of efficient methods for the synthesis. This study involved the synthesis of MnO nanoparticles through a simple, cost-effective, and time-efficient co-precipitation method by using manganous sulphate (0.03 M) and sodium hydroxide (0.009 M). The UV-Vis absorption showed sharp absorption at 320 nm confirming the presence of MnO nanoparticles. The FTIR spectral analysis depicted absorption bands at 480 cm-1 and 515 cm-1 correspond to the characteristic peak of the Mn-O bond and XRD spectra predicted the average size of synthesized nanoparticles to be 11 nm. The elemental composition of the nanoparticles was determined by EDX analysis. The synthesized nanoparticles showed significant antimicrobial activity against microorganisms, Staphylococcus aureus, Klebsiella pnuemoniae, and Candida albicans.

A total number of 20 Libyan honey samples were collected from different areas in Libya through 2016 – 2017 , from east, west, southeast and southwest regions. These samples were analyzed for six physiochemical parameters of honey control i.e.,pH, moisture, ash content, insoluble mater porline control and HMF . The aim of this study is to give view about the quality of Libyan honey, which is suffering from paucity of characterization data. The results of physiochemical characteristic of Libyan honey samples, the pH of Libyan honey samples range from 3.25 to 5.00 , with a mean of 4.101 . These values are comparable to the pH values of U.S. honey (range 3.4 to 6.1), the moisture content of honey samples range from 7.76 to 15 % which is found within the limits prescribed by Codex Alimentarious Commission(1969), i.e. not more than 21%.The mean of ash content of honey samples were 0.313 %, with the range of 0.1-0.95 %. These values are comparable to the values of U.S. honey which has mean of o.169%, with a range from 0.020 to 1.028%.The Hydroxymethylfurfural (HMF) content of Libyan honey samples are found within the limits prescribed by the Codex Alimentarious Commission(1969), Insoluble matter content of Libyan honey samples range from 0.005 to 0.149 % . with mean of 0.06175 % . The range of proline content of Libyan honey samples arek from 350 to 1079.4 mg / kg, with mean of 626.2 mg / kg.

Fluorescent sensors have emerged as powerful tools in analytical chemistry, enabling the detection and quantification of specific analytes or target molecules. This review provides an in-depth analysis of different approaches in designing of fluorescent sensors. It explores the selection and modification of fluorophores, the incorporation of molecular recognition elements, and the utilization of various sensing mechanisms. Research and advancements in this field continue to enhance the capabilities of fluorescent sensors, making them indispensable in various scientific disciplines and driving future developments in analytical chemistry.