امید آذری

Cell therapy is applied in tendonitis to speed the healing process of tendon tissue and restore its functional properties. Almost all types of stem cells can differentiate from the recipient cells after transplantation.

The main goal of this study is to compare the effects of two sources of mesenchymal stem cells on tendon regeneration.

This study randomly divided 32 New Zealand rabbits into 4 groups. The bacterial collagenase was induced at the superficial digital flexor tendon (SDFT) of all rabbits, and the treatment was performed 48 hours after collagenase induction. Group 1 was treated with allogeneic bone marrow mesenchymal stem cells (BMMSCs). Group 2 was treated with adipose-derived stem cells (ADSCs) from the patellar ligament fat pad. Group 3 (sham group) was treated with 0.9% normal saline, and group 4 (control group) was left with no treatment. All rabbits were euthanized 2 and 4 weeks after surgery, and tendon samples were harvested. The histopathology was assessed by hematoxylin-eosin, Masson’s trichrome, and Vangieson’s dye, and tendon structure, fiber arrangement, cell nuclei, tissue inflammation, vascularity (angiogenesis), and density were surveyed.

The tendon healing process in the BMMSC and ADSC groups revealed better regeneration than the control and sham groups (P≤0.05). Significant changes (P≤0.05) in some microscopic parameters were seen by comparing the BMMSC and ADSC groups.

According to the present study, the injection of mesenchymal stem cells (BMMSCs or ADSCs) showed beneficial results in tendon tissue healing. Furthermore, ADSCs showed better regeneration of the injured tendon tissue than BMMSCs.

Functional planning of Iranian gardens as one of the potentials of sustainable development can increase the biological quality of the urban environment. As a result, the aim of the current research is to investigate the role of functional planning in creating sustainable buildings in Pahlavanpur garden in Mehriz, Yazd. The research method is developmental-applied in terms of type and in terms of method, it has nest to nest combination. First, semi-structured interviews were conducted with experts and the components of functional planning and sustainability were extracted, and then a questionnaire with a Likert scale was designed based on that and randomly distributed among 384 people who referred to Pahlwanpur Mehriz Garden in Yazd. Atlasti software is used to extract components and SPSS is used for descriptive and inferential statistics. The results indicate that the highest type of correlation is between empowering buildings and knowing the place with a value of 0.995, and then efficiency with environmental comfort with a value of 0.895, and in general, the variable of the efficiency of buildings has the highest correlation with other variables, and the least is related to the outcome and environmental comfort. In general, the lowest is related to the outcome variable with other variables.

From September 2016 to 2019, 74 horses with signs of colic were referred to the Veterinary Referral Hospital of Shahid Bahonar University of Kerman. In this article, surgical management of some of these cases from the time of admission to discharge is described.

Pulsed wave (PW) Doppler echocardiography provides a convenient and noninvasive tool for measuring cardiac output (CO) alternations after the administration of sedative drugs, but this is not a usual method for camelids.

The aim of the present study was to investigate the changes of the left and right ventricular outflow tracts (LVOT and RVOT), CO, and systolic time intervals following the intravenous (IV) injection of medetomidine (M) and xylazine (X) using PW Doppler echocardiography.

Twenty apparently healthy immature male one-humped camels (Camelus dromedarious) were selected and divided into four groups (five animals per group). Medetomidine and X were injected to the left jugular vein at two different doses of 10 and 20 μg/kg, and 0.2 and 0.4 mg/kg, respectively. Effects on echocardiographic parameters were assessed at 4 intervals: before, 3, 60, and 120 min after drug administrations.

Velocity time integrity (VTI), maximum/mean flow velocity (Vmax and Vmean) and maximum/mean pressure gradient (PGmax and PGmean) decreased in aortic and pulmonic valves. Left ventricular ejection time (LVET) and LVET + pre ejection period (PEP) decreased and PEP and PEP/LVET increased in all groups except the low dose X group, 3 min after drug administration (P<0.05). The least values of VTI, velocity (V), PG and CO were observed after 60 min in the low dose X group (P<0.05).

A relationship was found between the intensity and the duration of changes in cardiac parameters and both types and dosages of the injected drugs. We concluded that X and M have transient depressor effects on the ventricular outflow tract and CO of healthy camels.

A five-month-old male domesticated short hair cat with non-specific signs, weakness, coughing and dyspnea was referred to the clinic.

The patient was primarily diagnosed with kyphoscoliosis induced by severe nutritional osteoporosis. After couple of days the case was referred without improvement in condition. Contrast radiographs revealed esophageal hiatal hernia.

Surgery was successfully performed to reduce the size of the esophageal hiatus, esophagopexy and left fundic gastropexy. The case returned to a normal condition after a week. A two year follow up showed no recurrence.

It is concluded that kyphoscoliosis caused by severe nutritional osteoporosis could be a predisposing factor for hiatal hernia in small animals.