راضیه فرازمند

Antibiotic resistance has contrived use of medicinal plants with less side effects instead of common drugs. The present study was done to investigate antibacterial effects of garlic ethanolic extract against antibiotic resistant Staphylococcus aureus strains isolated from nasopharyngeal samples. Extraction was done using vacuum distillation (rotary). A total of 17 Staphylococcal strains were isolated from nasopharyngeal swabs of in- and outpatients in Ali-Ebne-Abitaleb hospital (zabol). Antibiotic resistance was determined using Kirby Bauer method and minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of garlic extract was determined using micro-broth dilution method. Antibiotic resistance of the isolates was as follow: Penicillin (88. 2%)، Erythromycin (82. 4%)، Cefoxitin (82. 4%)، Trimethoprim (70. 6%)، Ampicillin (70. 0%)، Ceftazidime (29. 4%)، Tetracycline (23. 4%)، Ceftriaxone (23. 5%)، and Amikacin (5. 9%). The MIC and MBC for garlic extract were 1. 25 and 5 mg/ml resoectively. Garlic extract has high anti staphylococcal effects compared with common antibiotics and could be used as a benefit medicinal plant. However، it is suggest more studies to ensure its medical effects before wide medical usage.