فهرست مطالب فاطمه طالبی کیاسری

Mismatched-blood transfusions in the ABO-system may lead to severe of complications such as intravascular hemolysis.

Case report:

 A 49-year-old man suffering from a right lower limb injury due to accident was admitted to hospital. Vital signs were normal. X-ray showed a femoral neck fracture. Before surgery, all of lab tests were in normal values and B+ blood- group was reported. During surgery and due to blood loss, the patient underwent blood transfusion. At the end of transfusion, a mismatched blood bag was observed. The patient had received about 400 cc mismatched-blood. Transfusion was promptly terminated and the patient received extensive IV fluids in addition to a single dose of furosemide. The patient had stable status without signs of overt hemolysis. After 3 days stay at intensive care unit, he was transferred to the ward with a stable status.

In spite of mismatched blood transfusion, the patient did not experience severe adverse events. To prevent this problem, different steps of blood transfusion should be checked by anesthesiologist

Previous studies have indicated that the voluntary and swimming exercise decreases the severity of the physical and psychological dependence on morphine in morphine-dependent and withdrawn rats. The aim of the present study was to investigate the effects of the forced treadmill exercise during the induction of morphine dependence on naloxone-precipitated morphine withdrawal signs and anxiety like behavior.
Rats were injected with increasing doses of morphine (8, 16, 26, 36, 46, 56 and 64 mg/kg, daily, s.c.) over a period of 7 days in which they were also trained at mild intensity on a treadmill for 30 min of daily. The anxiety-like behaviors were tested 2h after receiving morphine injection (56 mg/kg) using the elevated plus-maze (EPM) on day 8. Then, the severity of morphine dependence was measured after an acute injection of naloxone (0.4mg/kg, IP), 2h after receiving morphine injection (56 mg/kg) according to a modified version of the Gellert–Holtzman scale on day 9.
The results showed that the withdrawal graded signs including abdominal contractions, weight loss, and overall Gellert–Holtzman score and among the checked signs; consisted of diarrhea, irritability and teach chattering were decreased in treadmill runner morphine-dependent rats than the sedentary rats. Also, the results showed that the treadmill runner morphine-dependent rats exhibited an increase in time spent in, and entries into, the EPM open arms than the sedentary morphine-dependent groups.
Our findings indicated that the forced treadmill exercise during the induction of morphine dependence diminished the severity of dependence on morphine and anxiety like behavior. Thus, forced treadmill exercise may decrease some of the behavioral consequences of physical and psychological dependence on morphine.

Hirsutism as a clinical presentation of hyperandrogenism has a negative impact on the mental health and quality of life. Therefore, determination of its prevalence and associated factors in communities are important. The aim of this study was to determine the prevalence of hirsutism and its associated factors in dormitory students of Semnan University of Medical Sciences in Semana, Iran.
In this cross-sectional study, all of the female students of Semnan University of Medical Sciences dormitory were given a questionnaire which consists of three parts. The first two sections was designed to collect the demographic data and medical history including past medical history, drug history, menstrual condition and familial history of hirsutism. The third section included the grading scale of Ferrimen-Gallwey, that contains images of various parts of the body and hair growth. Participants were asked to determine their hair growth on the pictures. Data was analyzed using IBM SPSS Statistics (IBM Corp., Armonk, NY, USA) version 19. Chi squared test was used for comparison of proportions in different groups.
From 330 participants, 119 students (36.1%) complained from hirsutism. 105 (31.8%) patients had mild and 14 (4.3%) students had moderate hirsutism. There was a significant correlation between hirsutism and irregular menstrual cycles, positive familial history of hirsutism, congenital adrenal hyperplasia, polycystic ovary, hypothyroidism, use of danazol, and hoarseness (P This study showed a high prevalence of hirsutism in dormitory students of Semnan University of Medical Sciences. More clinical evaluation is suggested to determine various forms of hirsutism and the underlying conditions.

Addiction is a chronic and relapsing disease. Relapse phenomenon in addiction treatment is the most important challenge. In spite of high efficacy of synthetic drugs recent studies have shown that they are often associated with unpleasant and undesirable side effects. Additionally current treatments have little effect in addiction treatment. Medicinal plants contain natural effective materials with lower costs and fewer side effects can be effective in the treatment of different stages of addiction. Since experimental studies are the basis for human studies. Thus, the aim of this study is to review the use of medicinal plants in the treatment of addiction in laboratory animals. In this review, all relevant original research papers and articles in physiology Research Center, Semnan University of Medical Sciences have been published in prestigious journals were analyzed. Up to now, very few scientific studies on the effects of medicinal plants in reducing withdrawal symptoms in humans have been conducted. Therefore, the results of this study on laboratory animals showed that medicinal plants can affect the body's biochemical functions and psyche, behavior, emotions and other addicts problems and be also effective in reducing the symptoms of withdrawal and addiction treatment to. The results of this study indicated that the plants can be effective to control deprivation, reduction of dependence development and probably in detoxifying in rats.