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This article employs a research methodology that involves the analysis of Morteza Momayez's works, specifically focusing on five posters from his cinematic portfolio. The selection of these posters was based on their relevance to the historical context of Iran, encompassing the periods preceding the Islamic Revolution, the imposed war between Iraq and Iran, and the post-war era. The research approach adopted is descriptive-analytical, utilizing library resources as the primary source of information. Furthermore, the study draws upon the conceptual framework of Gilles Deleuze, in collaboration with Guattari, particularly their molecular-molar theory. Within this theoretical framework, concepts such as the Rhizome, which symbolizes the interconnectedness of events, play a significant role. This research endeavors to explore and relate these concepts, including desire, Rhizome, deterritorialization, territorialization, molarity, and molecularity, to Morteza Momayez's movie posters. The selected movie posters for analysis include "The Mongols" (1973) by Parviz Kimiavi, "The Lodgers" (1987) by Dariush Mehrjui, "Mother" (1991) by Ali Hatami, "Oh Iran" (1990) by Nasser Taghvai, and "The Artist" (1993) by Mohsen Makhmalbaf.

From a molecular-molar perspective, Guattari's art serves as a reflection and mirror of society and the human psyche. Consequently, the interpretation of these posters necessitates an examination of the events that transpired during the specified years, spanning from the pre-Islamic Revolution era to the post-1978 revolution era of Iran's reconstruction. Morteza Momayez's movie poster works exhibit a deliberate deconstruction and departure from conventional design norms, which are evident in all five posters. In addition to capturing the essence of the films and their actors, Momayez paid meticulous attention to typography, size, and even adopted unconventional approaches to presenting the artists' names. Guattari's concept of "becoming," which elucidates collective transformation and dynamism, finds rich representation in Morteza Momayez's movie posters.

This article provides a comprehensive analysis of all five posters, considering the contextual events and Morteza Momayez's artistic perspective. The affinity between Guattari's molecular-molar theory and these posters was thoroughly explored and examined. Through the lens of Guattari and Gilles Deleuze's philosophical concepts, the authors sought to unravel additional layers of meaning embedded within these artworks, showcasing the creative prowess of Morteza Momayez. The analysis revealed that the movie poster for "The Mongols" (1973) exemplifies the concept of a "limbless body," while the poster for "The Lodgers" (1987) encompasses notions of "minority," "becoming," and "stratum." "Mother" (1991) portrays "territoriality" and a " limbless body" while "Oh Iran" (1990) exhibits the concept of "desire" and in "The Artist" (1993), several conceptual themes are discernible, including notions of "individuality," "abyss," and "tribal thought". Consequently, it is evident that Morteza Momayez's movie posters bear the molecular-molar roots of Pierre-Félix Guattari's theory.

According to me, his commentator terry Gilliam allows his characters to float in the heart of topics such as archetypes, narratives, history, time and place, to be redefined by Gilliam as unique phenomena. The researcher aims to discover the secondary meanings of the world of Terry Gilliam's screenplay texts in a dialectical process and intends to interpret Gilliam's screenplays based on Ricoeur's hermeneutic views. The researcher aims to discover the secondary meanings of the world of Terry Gilliam's screenplay texts in a dialectical process and intends to interpret Gilliam's screenplays based on Ricoeur's hermeneutic views. Ricoeur believes that in order to give wings to the imagination, reality must be suspended, so that by returning to the nature of objects and filling in the role of metaphors within the text, we can remove their original meaning and add new meanings to them. By this definition, the function of the power of the human imagination in Gilliam Berg's works is a winner for him so that the heroes of his works can advance the story in an unreal world. Examples that Gilliam has hermeneutically addressed in screenplays, can be traced back to storytelling, redefining narratives, joking with myths, and redefining stories with a transhistorical approach.In a descriptive-analytical way, the researcher intends to move towards the nature of phenomena and the interpretation of secondary concepts of Gilliam's screenplays in order to better understand this artistic approach to the manifesto of surrealism through phenomenological reading.

Modernism is a mental and intellectual approach by modern human; a mind that became a new change facing life crisis and manifested the various aspects of life using art medium. Modern period started a fundamental change; therefore, the artist converted the art meaning by its stream of consciousness. The author, poet and painter of the modern period embodied the self-concept of surrounding issues using an innovative thought. Achieving differences made the dynamic mind of the modern artist to research in order to create a world free of any representation after its subjective powers. On the other hand, art pundits appeared with new attitudes and express their iconoclastic opinions on representation avoidance concepts in modern art. Gilles Deleuze and Nelson Goodman are 20th century philosophers, who cohered a special paradigm on this period by presenting useful concept. The writer believes that recognition and perception of modern artistic works get a new concept considering opinions of these two great theoretician. Modern literary and visual works, abandoning the former representation tradition, changed to a form of anti-representational and modeling based on the concepts submitted by the mentioned philosophers provided a range of new thoughts. Focusing on painting and literature as two artistic eras, this research tries to renovate a different aspect of representation, by connecting them together. What is to be questioned is, on what concepts was the representation concept in the worldview of artists and theoretician in the modern period based and how it was affected?

There is an urgent need for reliable in vitro liver models to assess the mechanisms of human diseases, and impact of newly developed drugs or toxins. Previously showed that co-culture of hepatocytes with non-parenchymal cells and presence of extracellular matrix (ECM) improve the in vitro functionality of hepatocytes. Aim of this study was to develop a reproducible method for scalable generation of liver microtissues.

In this experimental study, liver microtissues with 500um diameter generated through co-culturing of Huh-7, human mesenchymal stem cells and human umbilical vein endothelial cells in a composite hydrogel of liver-ECM and alginate. Cell viability, capability for glycogen storage and cytochrome P450 enzyme activity were evaluated on day 28. Hepatic-specific genes (ALB and SULT1A1) on days 1 and 14, and albumin and urea secretion on days 1, 7, 14, 21 and 28 were assessed. Furthermore, the microtissue sensitivity to acute toxicity of Metformin, Diclofenac and ethanol were investigated. Two-dimensional cultured Huh-7 was considered as control group.

Most cells in the microtissues were alive up to day 28, accumulated glycogen and have cytochrome inducibility 7-fold more than the basic activity. In comparison to control, ALB and SULT1A1 genes upregulated (p<0.05) on day 14, also albumin and urea secretion increased (p<0.05), in all sampling time, in microtissues. Furthermore, microtissues have more sensitivity (p<0.05) to some concentrations of the drugs and ethanol, compared to control.

It seems that the liver microtissues may considered as an appropriate and functional in vitro model for liver.

Premature ovarian failure is a syndrome causing amenorrhea, infertility, and increases gonadotropin levels before age 40. The use of chemotherapy drugs can be one of the reasons that lead to this disorder. The purpose of this study was to evaluate the presence of germ cells markers in mice model of premature ovarian failure following chemotherapy drugs.

In this study, 24 mature female mice were used to create a premature ovarian failure model, different amount of cyclophosphamide and busulfan were applied (experimental groups 1 to 5). Bodyweight change, vaginal smear, morphological alternation of ovarian tissue in both experimental and control (without treatment) groups were evaluated and for the best model, hormonal evaluation (FSH, E2), and expression of germline markers (Oct4, Dazl) were examined.

Since, in the second group estrus cycle disorder, the significant decrease in weight and ovarian reserve (p˂0.05) were observed, compared to the control group, so this group was chosen as the best model. An increase in FSH level and reduction in estradiol level in the second group, compared with the control group (p˂0.05), confirmed creation of the POF model. Also, genes expression of Oct-4 and Dazl showed an increase (p˂0.05) in the second group compared with the control one.

The presence of germ cells markers in a mouse model of premature ovarian failure following the use of chemotherapy drugs can be a new hope in the treatment of infertility in cancer patients after chemotherapy.

Each year, 111 million case of rotavirus diarrhea are reported. There is no specific therapy to treat rotavirus diarrhea, effective contraception should be considered. Considering water and food hygiene appears to have little effect on disease control, vaccination is the only way to reduce death caused by rotavirus diarrhea. In the current study, using modern genetic engineering method, a Polypeptid composed of several antigenic epitopes is made which can be used as a vaccine for rotavirus if its efficiency is cinfirmed. In this study, the prevalence of different species of viruses in Iran was examined. Serotype A was been the most common serotypes. The complete genome sequence was been, antigenic structure of the virus surface proteins were predicted by the of bioinformatics tools including Hex software and server Phyre. Four epitopes of the two virus surface proteins were identified and their genomes were sequenced. Primers were designed by use of software Genrunner in the way that each primer pair formed an epitope. Primers had overlapping areas, SOE-PCR method was used to connect them. In the gel electrophoresis, primers binding and the components growth are clearly seen. Combined fragment was cloned and initial expression was studied in prokaryotic system. The final product was place exactly at the desired place in comparison whit the marker according to molecular weight. Implementing SOE-PCR method in the study, encoding sequence of four epitopes of two rotavirus protein had bind together and new recombined piece was expressed in prokaryotic system. New recombined protein was in the expected place in terms of molecular weight.

Fuzzy classification systems play an important role in dealing with uncertainty and vagueness inherent in multi-dimensional pattern classification problems. Finding an optimal fuzzy rule set is a milestone in designing fuzzy classification systems. In this paper, a fuzzy Genetic Algorithm (GA) is developed to generate fuzzy classification rules. The proposed algorithm produce an optimal rule set in terms of number of rules and accuracy. Hence, in this research the optimal rule set consists of appropriate number of fuzzy rules in order to maximize the number of correctly classified patterns. In order to illustrate the efficiency of the proposed method, it is applied to Iris dataset and a collection of data contained in 2D images captured by a video camera to identify the class of moving objects in a traffic scene. The simulation results are also compared with other methods.

There is much more attention to the synthetic biomaterials for bone and teeth reconstruction in the recent years. Hydroxyapatite and its derivatives like fluorohydroxyapatite are categorized in this group. In this research, hydroxyapatite and fluorohydroxyapatite powder were synthesized by hydrothermal method. The biological response of the human osteoblast and mesenchymal stem cells in contact with these materials were evaluated. Cell proliferation assay (MTT), alkaline phosphatase secretion and the also expression of collagen type I and alkaline phosphatase as the biological activity criterion of these materials were assessed. The results showed that fluoride can increase the rate of osteoblast proliferation and gene expression. However there was no significant observation in the cell proliferation rate and gene expression between two differentsamples of hydroxyapatite and fluorohydroxyapatite. In addition, it has been shown that the amount of alkaline phosphatase and gene expression in osteoblast cells were higher than mesenchymal stem cells.