مطهر رهنمای قلعه رودخانی

Organic acids are one of the alternatives to antibiotics growth promotor which have beneficial effects on animal performance and gastrointestinal microbial population. In general, addition of organic acids into the feed lowers pH of the feed and gastrointestinal tract, stimulates growth, helps beneficial bacteria to overcome pathogenic bacteria, and reduces toxic metabolites produced by harmful bacteria.

A total of 240 day-old Ross 308 male broiler chicks were divided into 4 treatments, 4 replicates, and 15 broiler chickens per replicate in a completely randomized design. Experimental treatments were included 0, 200, 300 and 500 mL of acidifier in 1000 L drinking water.

Feed conversion ratio in broilers that received two levels of 200 and 500 mL of acidifier per 1000 liters in drinking water decreased compared to the control treatment (p<0.01). European efficiency index was higher in the whole acidifier levels than the control and a linear increasing trend was observed (p<0.05). Broilers received 500 mL of acidifier in water had the lowest FCR (1.64 vs. 1.80; p<0.01) and the highest EEF (394 vs. 332; p<0.01) compared with the control. The weight of bursa of Fabricius, spleen and pancreas in broilers received graded levels of acidifier was higher than the control (p<0.05). The pH of the proventriculus, duodenum and jejunum of broilers that received 500 mL of acidifier decreased compared to the control (p<0.05). Administration of graded levels of acidifier in drinking water had no effect on Lactobacillus, coliforms and Escherichia coli count in ileum (p>0.05). The thickness of the lamina propria layer increased in broilers received 300 mL of acidifier (p<0.05). Administration of acidifier in drinking water had no effect on antibody titer against SRBC and Newcastle.

The results indicate that adding 500 mL of acidifier in 1000 L drinking water improves growth performance by increasing the weight of digestive organs such as pancreas and acidifying the initial areas of the digestive tract.

Organic acids are one of the alternatives to antibiotic growth promoters. They have beneficial effects on poultry performance and gastrointestinal microbial balance. In general, the addition of organic acids to the diet lowers the pH of the diet and gastrointestinal tract, stimulates growth, helps to overcome the population of beneficial bacteria over pathogenic bacteria, and reduces toxic metabolites produced by harmful bacteria. The purpose of this study was to determine the antibacterial effects of encapsulated versus non-encapsulated organic acids (OA) supplementation in drinking water on intestinal microbiota and broilers' growth performance.
A total of 360-day-old Ross 308 male broiler chicks were divided into six treatments, four replicates, and 15 chicks per replicate in a completely randomized design. The experimental treatments included: a negative control (without organic acids; OA, in drinking water), a positive control (200 mL of a commercial OA, acidifier 4+ in 1000 L drinking water), 500 and 1000 mL non-encapsulated blend of OA, and 500 and 1000 g encapsulated blend of OA in 1000 L drinking water. The blend of OA was composed of butyric, propionic, and acetic acids. Body weight and feed intake were measured weekly on a pen basis. From these data, average daily gain (ADG), average daily feed intake (ADFI), average daily water intake (ADWI) and feed conversion ratio (FCR) were calculated over the total rearing period. The European production efficiency factor (EPEF) was also calculated for the entire period of the trial. On day 42, gastrointestinal samples were collected from a total of 48 sacrificed birds (n = 12 birds from each experimental group) for pH and microflora analysis. Digesta from different sections of the gastrointestinal tract was collected and pH was measured using a digital pH meter. Total coliforms, lactobacilli, and Escherichia coli were counted in ileal digesta using a plate method with the use of a specific medium.
Broilers with an encapsulated blend of OA in drinking water had higher (P<0.05) body weight, ADG, and EPEF, and lower (P<0.05) FCR than the negative control. Broilers in the PC group and those with OA in their drinking water exhibited greater final BW, ADG, and FCR than those in the NC group (P<0.05) throughout the rearing period (0 to 21 d, 22 to 42 d, and 0 to 42 d). Organic acids can improve broilers' performance by inhibiting the growth of pathogenic bacteria in the intestine. In the current study, administration of encapsulated OA in the drinking water of broilers resulted in lower (P<0.05) pH in jejunum when compared to the negative control. Dietary organic acids reduced the pH of different sections of the gastrointestinal tract of broilers compared to those fed the control diet. The administration of 500 g encapsulated or 1000 mL non-encapsulated blend of OA in the current study resulted in a lower count of E. coli compared with the negative control (P<0.05). The count of E. coli was linearly decreased (P<0.05) in the ileum of broilers with graded levels of the non-encapsulated blend of OA. It seems that the gizzard and stomach of birds drink acidified water were more acidic and might decrease the bacteria that were present in the gastrointestinal tract, especially in the lower gastrointestinal tract. Organic acids provide acidic pH in the gut, which increases beneficial bacteria, and decreases harmful bacteria of broilers.
Growth performance and the European production efficiency factor were generally greater with encapsulated OA compared with non-encapsulated one. Results of the current study showed that administration of 500 mg encapsulated blend of OA was sufficient for achieving the desired results.