وحید ولی پور

Physical activity has a positive effect on angiogenesis and inflammation indexes, but its effect on people who intake a high-fat diet is not clear. Therefore, this study aimed to determine the effect of 8 weeks of interval activity on serum levels of angiogenesis factors and inflammatory index predicting cardiovascular disease on high-fat diet rats.

In this experimental study, 30 male Wistar rats (6 weeks old) were randomly assigned in 3 groups; normal diet (n=10), high-fat diet (n=10), and high-fat diet-interval training. For the first and second groups, the training program was performed 5 days a week for 8 weeks. Before the first session and 48 hours after the last session of physical activity, blood samples were taken using the ELISA method to examine NO, VEGF, and CRP. the MANOVA test was used to analyze data

The results of this study showed that 8 weeks of interval training increased significantly (p<0.0001) NO and VEGF (P=0.0001) levels in the high-fat diet-interval training group compared to the control group and high-fat diet group. However, the CRP level of the high-fat diet-interval training group decreased significantly (P=0.0001) than the control group.

according to the findings of this study, 8 weeks of interval training increase some angiogenesis factors such as NO and VEGF, which results in the probable reduction of CRP as a risk factor of cardiovascular disease.

β-tubulin protein is the protein that has a key role in plasticity and neurogenesis in the mature neurons. On the other hand, endurance training is effective in neuron life and lifespan. The present study aimed to investigate the effect of 20 days swimming training on class III β-tubulin and the number of ganglion cells in DRG of Wistar male rats.

In this experimental study, 16 male Wistar rats (healthy) weighing 200-250 gr were randomly divided into control and exercise training groups. The exercise training group performed a swimming training program for 20 days, the control group did not participate in any activity. In the following, the ganglionic cells population and β-tubulin protein level in the posterior root of the spinal cord was measured by Cresyl violet staining method and immunofluorescence, respectively. Finally, data were analyzed using the independent t-test.

The results showed that swimming activity significantly (p=0.0001) increased beta-tubulin protein in the experimental group. Also the a significant increase in the ganglion cells population was observed in the spinal cord posterior root of the experimental group compared to the control group (p=0.0001).

Swimming endurance activity may have a protective and restorative effect by increasing neurogenesis on dorsal root ganglion neurons.

Mitochondrial biogenesis is related to Ppargc1α and Atf2 genes. Endurance training through PGC-1α and Atf2 induces mitochondrial biogenesis, but it seems that air pollution has the opposite effect. Therefore, this study aimed to investigate the effect of endurance training in air pollution on PGC-1α and Atf2 genes expression in brain cortex mitochondria of Wistar male rats.

In this experimental study, 32 eight-week-old rats (weight: 180.77±10.65) divided into four groups: control, training, pollution, and training+pollution. In order to expose animals to air pollution, a 9000-liter chamber was used. The training was performed for eight weeks. 24 hours after last session, brain cortex was extracted. The expression of genes was measured using RT-PCR. The two-way ANOVA was used to analyze the data.

Atf2 gene expression was significantly different in the training+pollution group compared to the control group (P=0.04). In addition, Atf2 gene expression was significantly different in the training group compared to the control group (P<0.01). Also, PGC-1α gene expression was significantly different in the training group compared to the control group (P<0.01). Also, PGC-1α gene expression was significantly different in the pollution group compared to the control group (P<0.01). But, PGC-1α gene expression was not significantly different in the training+pollution group compared to the control group (P<0.05).

Pollution has no effect on Atf2 gene expression, but training in both conditions increases it. Also, pollution reduces PGC-1α gene expression but training increases it. Therefore, it seems that expression of PGC-1α in air pollution is also influenced by other factors.

Women with breast cancer do not have a desirable antioxidant defense system, especially catalase, lipid oxidation and aerobic power. Considering the effect of exercise training on these factors, the present study aimed to investigate the effect of eight weeks of high intensity circuit training on serum levels of catalase and malondialdehyde, and the aerobic power in breast cancer survivors.

In this semi-experimental study, 17 women rescued from breast cancer volunteered and randomly divided into two groups of exercise (n=9) and control (n=8). Subjects participated in an 8-week HICT protocol that performed 3 sessions per week. 24 hours before and 48 hours after the training protocol, the fasting blood sample was taken by the laboratory expert between 7:30 minutes to 8 hours. Serum levels of catalase and malondialdehyde, and maximum oxygen consumption were measured. The analysis of covariance was used to identify any significant differences and statistical significance was set at P<0.05.

The results showed that Waist-to-hip ratio (WHR) (P=0.90), weight (P=0.284) and malondialdehyde (P=0.154) had a non-significant difference and in the variables of Vo2max (P=0.0005) and catalase (P=0.036) there is a significant difference between the two groups.

It is suggested that short-term and effective exercise training such as HICT training, should be used with a view to facilitating and beneficial effects for women with breast cancer in order to reduce oxidative stress and improve aerobic capacity as a non-pharmacological supplement.

Physical activity is an effective stimulant for improving the health of elderly people with metabolic syndrome by increasing energy consumption and thus reducing body fat. The purpose of this study was to investigate the effect of 8 weeks of high intensity circuit training (HICT) on serum BDNF and Irisin levels and body weight in elderly women with metabolic syndrome in Khorramabad city.

In this semi-experimental study, 18 females (age 71.00 ± 6.17 years; weight 62.22 ± 9.18 kg; height 153.67 ± 3.27 cm) with metabolic syndrome voluntarily participated. During their daily routine, the subjects participated in an 8-week HICT protocol that performed 3 sessions per week. 24 hours before the training protocol and 48 hours after the training protocol, the fasting blood sample was taken by the laboratory expert between 7:30 minutes to 8 hours. ELISA kits were used to measure serum levels of BDNF and Irisin. The paired-Samples T test was used to identify any significant differences and statistical significance was set at p < .05.

The results showed a significant increase in serum BDNF (p = .001) and Irisin (p = .033) levels and significant decrease in body weight (p = .001) in comparison with pre-test values in elderly women with metabolic syndrome.

High intensity circuit training in elderly women with metabolic syndrome increases serum BDNF and Irisin concentrations and possibly, the increase in these two factors can have beneficial effects on the lipid profile and finally body weight of these individuals.

Physical activity is one of the ways to prevent and control metabolic diseases, such as diabetes. In the present research, the effect investigate the effect of 8 weeks of circulatory resistance exercise, was investigated on the indices of type 2 diabetes in the middle-aged women.
In this semi experimental study, 16 women (mean age, 44/9±2/35 years), were voluntarily selected and randomly assigned to two groups of control and experimental. A pre-test was taken from the both in terms of indicators of interest (weight, height, waist circumference, hip circumference, body fat percentage, fasting blood sugar, and glycosylated hemoglobin). The experimental group performed a period of circulatory resistance exercise (8 stations, 4 rounds, 3 days per week for 8 weeks). At the end of this period, the mentioned indicators, were again assessed as the posttest. Data were analyzed using independent t-test at the significant level of p In this study, the mean body weight, body fat percentage, waist circumference, fasting blood glucose level, and the mean of glycosylated hemoglobin in the experimental group were significantly higher compared to the control group (p=0.001), whereas a significant difference (p=0.63), was observed in the mean body mass index between experimental and control groups.
Based on the results of this study, resistance exercise, such as endurance exercise leads to optimal control and improvement of diabetes-related indicators in the middle aged women