m bassami

High blood pressure affects nearly 30% of adults. Inactivity and low intake of antioxidants are associated with increased risks of high blood pressure and cardiovascular diseases. High intensity interval exercise increases blood pressure and oxidative stress. The purpose of this study was to investigate effects of L-citrulline consumption on oxidative stress and antioxidant indices after high intensity intervals of hypertensive patients.

Subjects of this study included 12 hypertensive men (age 46.54 y ±5.05) who after six d of L-citrulline (6 g) or placebo (6.2 g) intake carried out high intensity interval exercise in crossover manners. High intensity interval exercise sessions consisted eight intervals of 1-min exercise with 80, 85, 90, 95, 100, 105, 110 and 115% of reserve heart rate and active recoveries of 1 min with 35, 40, 45 and 50, respectively. Moreover, 55, 60, 65, 70% of the reserve heart rates were on the bicycle ergometer. Blood samples were collected immediately after exercises and within 90 min of recovery.

High intensity interval exercises included significant effects on glutathine peroxidase (p = 0.001), superoxide dismutase (p = 0.001), total antioxidant capacity (p = 0.002) and malondialdehyde (p = 0.001) plasma levels. However, these changes were not significant after placebo and supplement consumptions.

Exercise regardless of L-citrulline and placebo intakes decreases oxidative stress and increases antioxidant in hypertensive patients.

Exercise is one of the lifestyle interventions recommended to reduce liver damage and improve health. The present study aimed to investigate the relationship between physical activity and physical fitness with the liver enzymes of COVID-19 patients.

Four hundred patients infected with COVID-19 (57.6±14.6, body mass 28.1±4.7 kg/m2) admitted to the Masih Daneshvari Hospital in Tehran participated in the present study. After Introducing with the work procedure, Beck and Stanford’s questionnaires were used to check their physical activity. Each participant filled out the physical fitness self-assessment questionnaire to self-report his/her physical fitness. Fasting blood samples were taken to measure aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, and lactate dehydrogenase.

The statistical analysis of the collected data revealed a significant correlation between physical activity with aspartate aminotransferase (p=0.035) and alanine aminotransferase (P=0.001), and there was a difference between different levels of physical activity. The results also showed is no significant relationship between alanine (p=0.068) and aspartate aminotransferase (p=0.375) with physical fitness. However, there was no significant relationship between physical activity and physical fitness with alkaline phosphatase (p =0.271) and lactate dehydrogenase (p =0.311).

According to the findings, it can be concluded that regular physical activity prior to COVID-19 infection is associated with high levels of liver alanine aminotransferase and aspartate aminotransferase.