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masoud nazeri

  • Masoud Nazeri *, Seyed Jalal Tabatabaei, Yavar Sharafi

    Water is one of the most significant factors limiting the production of horticultural crops. To confront drought stress, an experiment was designed as a factorial in the form of a randomized complete block. Treatments included placing the pumice bag next to the tree in two levels — [no bag (B0), one bag (B1)], different levels of irrigation — [50% (I50), 75% (I75), and 100% (I100)] — and root inoculation with fungi — [mycorrhiza (Fm), Trichoderma (Ft), and no fungus (F0)]. The highest LA and SLA were measured in the B0I100Ft treatment. The maximum chlorophyll index was measured in the B1I75Ft treatment. The highest yield was measured in the B1I100Fm treatment, which increased yield by 2.1 times compared to the control. Treatments that placed the bag next to the tree and had a sufficient irrigation level yielded more. The highest concentrations of N, Zn, and K were measured in treatments with lower irrigation levels. Only irrigation and bag placement had a significant effect on P. The highest phenols, anthocyanins, antioxidants, and vitamin C were measured in the B0I50F0, B0I75F0, B0I50Ft, and B0I75Fm treatments, respectively. According to the results, the B1I75Fm treatment saved 25% in water consumption, while maintaining good fruit productivity and quality.

    Keywords: Irrigation, Mycorrhiza, Pumice, Stress, And Trichoderma
  • Masoud Nazeri*, Seyed Jalal Tabatabaei, Nasrin Mollayi

    Sunburn is one of the significant problems in pomegranate growing, which reduces fruit yield and quality. This study was conducted to evaluate the impact of the application of antiperspirants on the quality and biochemical properties of pomegranate fruits. The experiment was carried out as a completely randomized design with nine treatments and three replications. Treatments include 2% solution talc (T), zinc oxide (ZnO), kaolin (K), zinc oxide+talc (ZnT), talc+kaolin (TK), zinc oxide+kaolin (ZnT), zinc oxide+talc+kaolin (ZnTK), shading with 50% light passing and control (sprayed with water). The highest edible fruit was measured in the ZnO treatment. The maximum and minimum thickness of fruit peel was measured in the control and shading treatments, respectively. ZnO treatment reduced the thickness of the fruit peel by 30.8% compared to the control. The lowest temperature of fruit and leaf was measured in shading and ZnT treatment, respectively. The control treatment produced the lowest Fv/Fm and leaf area, (LA), and the shading treatment resulted the highest Fv/Fm, LA and chlorophyll. ZnO treatment increased Fv/Fm and LA by 11.95% and 15.55%, respectively, compared to the control. The highest anthocyanin and phenol of juice were recorded in shading treatment. The highest fruit peel phenol and the lowest fruit peel lipoxygenase activity were measured in the ZnTK treatment. The results indicated that the ZnO treatment is a suitable treatment due to the decrease in the percentage of fruit peel and the increase in the Fv/Fm and the decrease in the activity of the lipoxygenase enzyme.

    Keywords: Abiotic stress, laccase, lipoxygenase, peroxidase, shade
  • Seyedeh Masoumeh Seyedhosseini Tamijani, Elmira Beirami, Hamed Ghazvini, Raheleh Rafaiee, Masoud Nazeri, Moazameho sadat Razavinasab *
    Background

    Methamphetamine (MA), is a widely abused synthetic psychostimulant that leads to irreversible brain damage manifested as cognitive impairments in humans and animals. The novel object recognition (NOR) task is a commonly used behavioral assay for the investigation of non-spatial memory in rodents. This test is based on the natural tendency of rodents to spend more time exploring a novel object than a familiar one. NOR test has been used in many studies investigating cognitive deficits caused by MA in rodents. The objective of the present study was to review neurobiological mechanisms that might be responsible for MA-induced NOR alterations. 

    Methods

    A PubMed search showed 83 publications using novel object recognition and methamphetamine as keywords in the past 10 years. 

    Findings

    The present study revealed different MA regimens cause recognition memory impairment in rodents. In addition, it was found that the main neurobiological mechanism involved in MA-induced recognition deficits is the dysfunction of monoaminergic systems. 

    Conclusion

    NOR is a useful test to assess the cognitive functions following MA administration and evaluate the efficacy of new therapeutic agents in MA-addicted individuals.

    Keywords: Methamphetamine, Novel object recognition test, Monoaminergic systems, Cognitive Impairment, Rodents
  • مسعود ناظری*، اکبر حسن پور

    بیش از یک دهه از ورود پدیده قلدری به ادبیات حوزه سازمان ایران می گذرد و دراین میان پژوهش های متعددی درباره آن انجام شده است. هدف پژوهش حاضر فراروش مطالعات انجام شده قلدری محل کار در جامعه ایران می باشد. براین اساس کلیه پژوهش های جامعه موردنظر از حیث روش-شناسی مورد بررسی و کنکاشت قرارگرفته است. این پژوهش از نظر هدف توسعه ای و شیوه جمع آوری داده ها، مطالعه کتابخانه ای می باشد. جامعه آماری پژوهش، تمامی مقالات منتشرشده در مجلات علمی-پژوهشی داخلی با موضوع قلدری محل کار است که شامل 32 مطالعه می شود. همچنین نمونه گیری پژوهش به صورت سرشماری بوده و همه عناصر جامعه مورد بررسی قرارگرفته است. این مطالعه در محدوده زمانی شش ماهه پاییز و زمستان 1401 صورت گرفته، و تمامی مقالات قلدری محل کار، قلدری سازمانی، قلدری محیط کار و قلدری شغلی از نظر 8 پارامتر شامل فراوانی پژوهش ها در هر سال، زمینه تخصصی پژوهشگران، وابستگی سازمانی پژوهش ها، رویکرد پژوهش، روش تحلیل داده ها، ابزار گردآوری، پیشایندها و پسایندهای قلدری، و محیط کاری مورد مطالعه، بررسی گردیده است. نتایج نشان می دهد که در اکثر پژوهش های قلدری از رویکرد کمی استفاده، و حوزه های بررسی شده به ترتیب، مربوط به سلامت افراد و سازمان، رهبری، جابه جایی کارکنان و سایر متغیرهای سازمانی می باشد. همچنین از ابتدای ورود قلدری به ادبیات سازمانی جامعه حاضر، سال های 1398 و 1400 بیشترین پژوهش ها را در خود جای داده که دانشگاه آزاد با ده پژوهش پیشتاز می باشد. در نهایت با توجه به نتایج مطالعه، پیشنهاد می شود پژوهش ها با رویکرد کیفی، فراتحلیل و فراترکیب انجام، تا پسایندها و پیشایندهای این نوع رفتار بهتر و بیشتر در فرهنگ حاضر درک گردد.

    کلید واژگان: رفتار انحرافی, قلدری محل کار, مطالعه فراروش
    Masoud Nazeri *, Akbar Hassanpoor

    More than a decade has passed since the bullying entered the literature of Iran's organization, and many researches have been conducted. The purpose of the present study is to analyze the studies of workplace bullying in Iranian society. Therefore, all the researches of the society in question have been studied and researched in terms of methodology. This research is development oriented and the method of data collection is library study. The statistical population of the research is all articles published in domestic scientific-research journals on the topic of workplace bullying, which includes 32 studies. Also for sampling, all elements of the society were investigated. This study was conducted in the six months of autumn and winter of 1401, and articles with the title of workplace bullying, organizational bullying, and occupational bullying in terms of 8 parameters, including: Frequency of researches in each year, specialized field of researchers, organizational affiliation of researches, research approach, data analysis method, data collection tools, antecedents and consequences of bullying, and the studied work environment., have been examined. Also, since the beginning of bullying in the organizational literature of the current society, the years 1398 & 1400 have contained the most researches, and Islamic Azad University has been the leader, with ten published researches. Finally, according of the study, it is suggested that the researches be conducted with a qualitative, meta-analysis and meta-synthesis approach so that the consequences and antecedents of this type of behavior can be better and more understood in the current culture.

    Keywords: deviant behavior, Workplace bullying, Meta-Method
  • مسعود ناظری*، اکبر حسن پور، سعید جعفری نیا، یوسف وکیلی
    هدف

    قلدری محل کار یکی از انواع رفتارهای انحرافی است که هزینه های مادی و معنوی زیادی را به بانک ها تحمیل می کند، اما تاکنون هیچ مدلی برای مدیریت آن ارایه نشده؛ بنابراین هدف پژوهش حاضر طراحی چارچوب مدیریت قلدری محل کار در صنعت بانکداری است.

    روش شناسی/ رویکرد

    مطالعه حاضر نوعی پژوهش کیفی بوده که از رویکرد نظام مند نظریه داده بنیاد برای انجام آن استفاده شده است. داده ها از طریق مصاحبه های عمیق و نیمه ساختاریافته با مدیران صنعت بانکداری جمع آوری، که بعد از مصاحبه با هفدهمین مدیر، به طور کامل از اشباع نظری و کفایت داده ها اطمینان حاصل شد.

    یافته ها

    پس از تحلیل داده ها با استفاده از فرآیند کدگذاری، 350 کد، 60 مفهوم و 6 مقوله حاصل شد. یافته ها نشان از شکل گیری چارچوب پژوهش حول پدیده محوری قلدری (آزار و رنجش مداوم) دارد، که شامل عوامل زمینه ای (ویژگی های شغلی- واکنش به قلدری و شدت آن- ویژگی جمعیت شناختی کارکنان)، عوامل علی (محیط مستعد قلدری)، عوامل مداخله گر (شخصیت- ارکان اجتماعی- نظام آموزشی- شرایط خانوادگی)، راهبردها (توسعه فرهنگ کارمند مدار- تدوین قوانین ضد قلدری- مدیریت اثربخش منابع انسانی) و پیامدها (فردی- سازمانی- اجتماعی) می باشد.

    ارزش/ اصالت پژوهش

    در این پژوهش علاوه بر شناخت پیشایندها و پیامدهای قلدری محل کار در فرهنگ حاضر، اهمیت جامعه در شکل گیری قلدری و تاثیر متقابل آن بر جامعه مشخص شد. همچنین مطالعه حاضر، عامل مهم در فرآیند قلدری را درک قربانی از این رفتار می داند.

    پیشنهادهای اجرایی/ پژوهشی

     پیشنهاد می شود از راهبردهای مطالعه حاضر، شامل تدوین قوانین ضد قلدری، توسعه فرهنگ کارمندمدار و مدیریت اثربخش منابع انسانی، به منظور کاهش پدیده قلدری و اثرات آن در صنعت بانکداری استفاده گردد.

    کلید واژگان: رفتار انحرافی, قلدری محل کار, نظریه داده بنیاد, صنعت بانکداری, آزار و رنجش مداوم
    Masoud Nazeri*, Akbar Hassanpoor, Saeed Jafariniya, Yoosof Vakili
    Purpose

    Workplace bullying in banks is a deviant behavior which has imposed huge physical and intangible costs on them; however, no model has ever been provided to manage it. This study is implemented to design a framework for workplace bullying management in the banking industry.

    Methodology

    The present study was of qualitative nature and used the systematic approach of grounded theory. Data were collected through in-depth and semi-structured interviews with the banking managers. After interviewing the seventeenth manager, theoretical saturation was reached.

    Findings

    With the analysis of data, 350 codes, 60 concepts and 6 categories were obtained. The final framework was formed based on the central phenomenon of workplace bullying (persistent harassment) which includes the following factors: a. contextual factors (job characteristics, reaction to bullying, demographic characteristics), b. causal factors (fit environment for bullying), c. mediating factors (personality, social elements, educational system, family conditions), d. strategies (developing employee-oriented culture, enacting anti-bullying laws, effective human resource management), and e. consequences (individual, organizational, social). 

    Originality

    In addition to recognizing the antecedents and consequences of workplace bullying in the current culture, the important role of society in the formation of bullying and its interaction with the society is identified. Also, according to the findings, the victim's perception of the bullying process is considered to be a significant factor.

    Implications

    In order to control the bullying phenomenon and weaken its effects on the banking industry, it is suggested that this industry applies such strategies as anti-bullying laws, employee-oriented culture and effective human resource management, which were presented in this research.

    Keywords: Deviant Behavior, Workplace Bullying, Grounded Theory, Banking Industry, Persistent Harassment
  • مسعود ناظری*، نسرین ملائی، سید جلال طباطبایی

    آفتاب سوختگی یکی از بزرگترین معضلات کشت انار است که منجر به کاهش عملکرد و کیفیت میوه می شود. به منظور ارزیابی اثر کاربرد مواد ضد تعرق بر کیفیت و خصوصیات بیوشیمیایی میوه انار، آزمایشی در شهرستان قم در قالب طرح کاملا تصادفی با نه تیمار و سه تکرار انجام شد. تیمارها شامل تالک (T)، اکسید روی (ZnO)، کایولین (K)، اکسید روی+ تالک (ZnT)، تالک+کایولین (TK)، اکسید روی+کایولین (ZnT)، اکسید روی+ تالک+کایولین (ZnTK)، توری با عبور نور 50 درصد و شاهد (محلول پاشی با آب) بودند. نتایج نشان داد که خصوصیات کیفی گیاه به طور معنی داری تحت تاثیر تیمار ها قرار گرفت. بیشترین ضخامت پوست میوه در تیمار شاهد و کمترین آن در تیمار ZnT مشاهده شد. بیشترین طول آریل مربوط به تیمار ZnK بود اما هیچکدام از تیمارها تاثیری بر روی قطر آریل، طول و قطر هسته انار نداشتند. بیشترین میزان فنل پوست در تیمار ZnTK ثبت شد و سایر تیمارها تقریبا در یک سطح معنی داری قرار گرفتند. کمترین میزان pH پوست و فعالیت آنزیم پراکسیداز آریل در تیمار توری مشاهده شد و تیمارهایی که ترکیبی از تالک، کایولین و اکسید روی بودند، بیشترین میزان فعالیت آنزیم پراکسیداز را داشتند. ZnK سبب افزایش 77 درصدی فعالیت آنزیم لاکاز نسبت به شاهد شد. بیشترین و کمترین فعالیت آنزیم لیپوکسیژناز در تیمارهای ZnTK و کایولین اندازه گیری شد. به نظر می رسد اکسید روی به دلیل ایجاد سطح مناسبی از پراکسیداز و کم کردن فعالیت لیپوکسیژناز و لاکاز تیمار مناسبی برای افزایش کیفیت میوه انار می باشد.

    کلید واژگان: انار, آفتاب سوختگی, پراکسیداز, لاکاز, لیپوکسیژناز
    Masoud Nazeri *, Nasrin Mollayi, Seyed Jalal Tabatabaei

    Sunburn is one of the most important problems in pomegranate cultivation, which results in reduced yield and fruit quality. This study was conducted to evaluate the effect of antiperspirant application on quality and biochemical properties of pomegranate fruits in Qom. The experiment was conducted as a completely randomized design with nine treatments and three replications. Treatments were talc (T), zinc oxide (ZnO), kaolin (K), zinc oxide+talc (ZnT), talc+kaolin (TK), zinc oxide+kaolin (ZnT), zinc oxide+talc+kaolin (ZnTK), shading with 50% light passing and control (sprayed with water). The results showed that the fruit quality characteristics were significantly affected by treatments. The highest fruit skin thickness was observed in control and the lowest was seen in ZnT treatment. ZnK treatment resulted in highest aril length, but the other treatments had no effects on aril diameter, length and diameter of pomegranate kernel. The highest fruit skin phenol content was seen ZnTK treatment and the other treatments were almost at similar significant levels. The lowest pH of the skin and aril peroxidase were observed in the Shading and the combination of talc, kaolin and zinc oxide had the highest peroxidase activity. ZnK enhanced laccase activity by 77% compared to control. The highest and lowest lipoxygenase activity were measured in ZnTK and kaolin treatments, respectively. Because of its good peroxidase level and lower lipoxygenase and laccase activity, the zinc oxide seems to be a good treatment for increasing the quality of pomegranate fruits.

    Keywords: laccase, lipoxygenase, Peroxidase, Pomegranate, Sunburn
  • مسعود ناظری*، جلال طباطبایی، یاور شرفی

    کاربرد روش های مناسب جهت افزایش راندمان گیاهان در استفاده از آب مهمترین عامل موفقیت در تولید محصول های باغی در ایران می باشد. برای کاهش تنش خشکی در هلوی رقم ردتاپ روی پایه GF677، آزمایشی به صورت فاکتوریل در قالب طرح بلوک های کامل تصادفی با سه تکرار صورت گرفت. تیمارها شامل جایگذاری کیسه در کنار درخت در سه سطح (بدون کیسه، دارای یک کیسه و دارای دو کیسه)، سطح های مختلف آبیاری (50، 75 و 100% ظرفیت زراعی) و مایه زنی ریشه ها با قارچ (بدون قارچ، قارچ مایکوریزا و قارچ تریکودرما) اعمال شدند. نتیجه ها نشان داد بیشترین شاخص کلروفیل و شمار میوه در تیمار جایگذاری دو کیسه، آبیاری کامل و مایه زنی با قارچ تریکودرما حاصل گردید که نسبت به شاهد افزایش 18درصدی و 8/1 برابری داشت. تیمار بدون جایگذاری کیسه، آبیاری کامل و مایه زنی با قارچ مایکوریزا و تیمار جایگذاری یک کیسه، آبیاری 75 % و مایه زنی با قارچ تریکودرما به ترتیب بیشترین رشد قطر تنه و رشد شاخساره را ایجاد کردند. تیمار بدون جایگذاری کیسه، آبیاری 75 % و بدون مایه زنی قارچ بیشترین ماده های جامد محلول و شاخص TSS/TA را ایجاد کرد. در کل جایگذاری کیسه میزان تنش خشکی را کاهش داد و تیمار جایگذاری یک کیسه و آبیاری 75 % و مایه زنی با قارچ مایکوریزا به دلیل افزایش شاخص های رشدی، عملکردی و کیفی پیشنهاد می شود.

    کلید واژگان: پومیس, تریکودرما, تنش خشکی, مایکوریزا
    Masoud Nazeri*, Jalal Tabatabai, Yavari Sharafi

    Improving water use efficiency in horticultural crops can be achieved by adopting appropriate practices. An experiment was conducted to reduce water stress in Peach var red top grafted on GF677. The experiment was arranged in a factorial completely randomized design with three replications. The treatments consisted of bag placement beyond tree trunk (0, 1 and 2 bag/tree), irrigation rate (50, 75 and 100 % of field capacity) and fugues (0, Mycorrhiza and Trichoderma). The results indicated that the highest content of chlorophyll and fruit number were observed in 2 bag 100 irrigation and Trichoderma treatment which 18% was higher than that of control. The increased both trunk diameter and stem growth were achieved in the treatment 0 bag, 100 irrigation, Mycorrhiza, 1 bag, 75% irrigation and Trichoderma, respectively. Treatment 0 bag, 75% irrigation and 0 fungi had the highest content of total soluble solid (TSS) and TSS/Titratable acidity. In general, the treatment of 1 bag, 75% irrigation and Mycorrhiza led to increased growth, yield and quality of fruits.

    Keywords: Drought stress, mycorrhiza, Pumic, Trichoderma
  • مسعود ناظری*، سید جلال طباطبایی، یاور شرفی
    آب مهمترین عامل محدودکننده تولید محصولات باغبانی بخصوص در کشورهایی مثل ایران است. کاربرد روش های مناسب جهت افزایش راندمان آب در درختان میوه، مهمترین فاکتور تولید مطلوب میوه می باشد. این پژوهش به صورت فاکتوریل در قالب طرح بلوک های کامل تصادفی با سه تکرار بر هلوی رقم Redtop پیوند شده روی پایه  GF677صورت گرفت. تیمارها شامل جایگذاری کیسه در کنار درخت به منظور هدایت ریشه به کیسه و ایجاد شرایط مشابه هیدروپونیک بود که در سه سطح بدون کیسه، یک کیسه و دو کیسه انجام گرفت. همچنین، جهت برآورد میزان کارایی سیستم ریشه منقسم در افزایش راندمان آب، سطوح مختلف آبیاری در سه سطح 50، 75 و 100 درصد ظرفیت زراعی انجام شد. جهت ارزیابی میزان افزایش راندمان آب توسط قارچ های موثر، تلقیح قارچ در سه سطح شامل بدون قارچ، مایکوریزا و تریکودرما اعمال شد. خصوصیات فیزیولوژیکی و عملکردی درختان 24 ماه بعد از کاشت مورد ارزیابی قرار گرفت. نتایج پژوهش نشان داد صفات رشدی برگ در اثر جایگذاری کیسه، تلقیح قارچ و افزایش سطح آبیاری افزایش معنی دار پیدا کرد. تیمار جایگذاری یک کیسه، آبیاری 75 درصد ظرفیت زراعی و تلقیح قارچ تریکودرما وزن تر و خشک برگ را به ترتیب نسبت به تیمار شاهد 62 و 52 درصد افزایش داد. شاخص های عملکردی قطر و طول میوه تحت تاثیر جایگذاری دو کیسه نسبت به بدون کیسه، 6 و 8 درصد افزایش پیدا کردند. جایگذاری کیسه و افزایش تنش آبی هر کدام میزان قند و اسیدیته قابل تیتراسیون را نسبت به شاهد افزایش دادند. قارچ مایکوریزا میزان اسیدیته قابل تیتراسیون و تریکودرما میزان سفتی میوه را نسبت به بدون قارچ، 9 و 32 درصد افزایش دادند.
    کلید واژگان: پومیس, تریکودرما, راندمان آب, مایکوریزا
    Masoud Nazeri *, Seyyed Jalal Tabatabaei, Yavari Sharafi
    The most important factor limiting the production of horticultural crops, especially in countries like Iran, is water deficiency. Application of appropriate methods to increase water efficiency in fruit trees is the most important factor for optimal fruit production. This study was conducted as a factorial randomized complete block design with three replications on Redtop peach trees grafted on GF677. Treatments included placing the bag near to the tree to direct the root to the bag and creating semi-hydroponic conditions that were performed at three levels without bag, one bag, and two bags. Also, to estimate the effects of the split root system in increasing water efficiency, different levels of irrigation were performed at three levels of 50, 75 and 100% of field capacity. Effective fungi inoculation at three levels including no fungus, Mycorrhiza glumus and Trichoderma harizanium were applied to evaluate the efficiency of water. Physiological and qualitative properties of saplings were evaluated 24 months after planting. The results showed that leaf growth parameters were significantly increased by bag insertion, fungal inoculation and irrigation. One bag placement, 75% irrigation capacity and inoculation of Trichoderma increased leaf fresh and dry weights by 62 and 52%, respectively. Fruit diameter and length were increased by 6 and 8%, respectively, in placement of two bags. Bagging was increased sugar content and titrable acidity compared to control. Mycorrhiza fungi enhanced titratable acidity and Trichoderma enhanced fruit firmness up to 9 and 32%, respectively.
    Keywords: Mycorrhiza, Pumice, Trichoderma, Water efficiency
  • Masoud Nazeri, Akram Nezhadi, Mohammad Shabani *
    Background

    Empathy is defined as the ability to simulate the mental states of others. Recent studies havedemonstrated empathy-like behaviors in other animals including rats and mice. The objective of the currentstudy was to evaluate the effect of acute administration of morphine and naloxone on cognition andnociception changes following observing conspecifics undergoing nociceptive stimulus.

    Methods

    Adult male Wistar rats were used (n = 8 for each group). One cagemate received formalin injectioninto the hindpaw five times within a nine-day period and the other cagemate observed the pain while beingpretreated with saline, morphine, or naloxone [10 mg/kg, intraperitoneal (i.p.)]. Pain behaviors, anxiety-likebehaviour, locomotion, balance and muscle strength were evaluated in the observer animals.

    Findings

    Observing a cagemate in pain increased anxiety-like behavior and reduced thermal pain threshold in theobserver animals. Administration of morphine reversed these effects and naloxone did not affect the responses.

    Conclusion

    Results of the current study reveal an important role for opioid receptors (ORs) in empathy forpain, so that activation of this system dampens the empathy-like responses.

    Keywords: Morphine, Empathy, Rats, Anxiety
  • مسعود ناظری*، اکبر حسن پور، سعید جعفری نیا، یوسف وکیلی

    امروزه یکی از مهم ترین چالش های پیش روی رفتار سازمانی، قلدری افراد در محیط کار است. براین اساس، هدف پژوهش حاضر، شناسایی پیشایندها و پسایندهای قلدری محل کار ازطریق فراتحلیل پژوهش های موجود در این زمینه است. این پژوهش ازنظر هدف، کاربردی، ازنظر نوع، توصیفی و ازمنظر ماهیت داده ها، کمی است. جامعه آماری پژوهش شامل 146 مقاله معتبر داخلی و خارجی بوده که 18 مورد آن با استفاده از روش قضاوتی وارد فراتحلیل شد. معیار انتخاب مقالات شامل استفاده از روش تحقیق معتبر، بررسی پیشایندها و پسایندهای قلدری، و تجربی بودن پژوهش است که برای تحلیل آنها از نرم افزار CMA2 استفاده شد. همچنین پایایی شناسایی ازطریق توافق داوران در انتخاب پژوهش ها و طبقه بندی آنها، پایایی کدگذاری ازطریق توافق داورها درباره استفاده از مفاهیم خاص برای کدگذاری متغیرها و پایایی سطح معنی داری و اندازه اثر ازطریق توافق در محاسبات اندازه اثر بین دو فراتحلیل گر به دست آمد. نتایج تحلیل نشان داد که بیشترین اندازه اثر میان پیشایندهای قلدری مربوط به استرس (56/0)، سکوت سازمانی (36/0)، مدیریت منابع انسانی (0/33)، ماکیاولیسم (0/31) و الزامات شغلی (0/3)، و بیشترین اندازه اثر پیامدهای قلدری مربوط به استرس (0/77)، تمایل به ترک خدمت (0/61)، عاطفه منفی (0/41) و فرسودگی شغلی (0/38) است.

    کلید واژگان: قلدری محل کار, پیشایندهای قلدری, پسایندهای قلدری, فراتحلیل
    Masoud Nazeri *, Akbar Hassanpoor, Saeed Jafarinia, Yousef Vakili

    Today, one of the most important challenges of organizational behavior is the Personnel bullying in the workplace. Accordingly, the aim of present study is to identify of workplace Bullying antecedents and consequences through the meta-analysis of existing researches in this field. This research is an applied one in terms objective, descriptive in terms of research type, and quantitative in terms of data nature. The Statistical population of the study includes 146 valid internal and external papers, 18 of which were evaluated using judgment method. The criteria for selection of articles include using valid research method, surveying of Bullying antecedents and consequences, and the empirical research, which it has been analyzed using the CMA2 software. Identification reliability was obtained by the referees’ agreement on the selection of researches and classification. The coding reliability was obtained by referees’ agreement for use of specific concepts for coding the variables, and also the reliability of the significance level and effect size are obtained by agreeing to calculate the effect size of between the two Meta analysts. The results showed that the most important antecedents of workplace bullying include Stress, Organizational silence, HR management, Machiavellian character and Job demand; also the most important consequences of workplace bullying include Stress, Turnover Intentions, Negative affectivity and Burnout.

    Keywords: Workplace Bullying, Bullying Antecedents, Bullying Consequences, Meta-Analyzing
  • Masoud Nazeri, Goli Chamani, Fatemeh Abareghi, Fatemeh Mohammadi, Mohammad, Hosseyn Talebizadeh, Reza Zarei, Mohammad Shabani*
    Objective
    Pain is a unique and subjective experience that has a prominent function in animals’ survival. Observation of pain in others leads to alterations in pain sensation and affection, termed “Empathy for pain”. The present study aimed to evaluate the effect of empathy on sensory and affective dimensions of pain and its effect on anxiety-like behaviors.
    Method
    In this study, male Wistar rats were used. Two cage mates were selected, one of which underwent administration of a noxious stimuli for 10 days and the other observed the conspecific in pain. Hot plate, tail flick, and conditioned place aversion were used to evaluate sensory and affective dimensions of pain, respectively. Anxiety-like behavior was assayed using elevated plus maze paradigm and time spent in open and close arms and number of entrance into each arm was recorded as the anxiety indicator within a 5-minute framework.
    Results
    Rats observing the cage mate in pain had a lower threshold to noxious stimuli in comparison to controls. They also had an increased aversion from painful stimuli, demonstrating heightened affective response to pain. Anxiety-like behavior was also enhanced in the observers.
    Conclusion
    Results of this study demonstrate that both sensory and affective dimensions of pain are altered following observation of pain in a conspecific. Further studies evaluating the underlying mechanisms are encouraged to elucidate the role of different neurotransmitters in this phenomenon.
    Keywords: Anxiety, Conditioned Place Aversion (CPA), Empathy, Pain
  • Nader Navabi *, Masoud Nazeri
    BACKGROUND AND AIM
     Helicobacter pylori (H. pylori) infection is one of the most common infections which still affects individuals worldwide. The main route for transmission of H. pylori infection is the oral route and this microorganism has been detected in dental plaque. In past decades, there have been a number of controversies about the station of dental plaque in the recurrence of gastric H. pylori Infection after eradication by triple therapy. In this study, attempts have been made to illustrate the current body of high quality evidence in this field.
    METHODS
     All relevant studies published between 2000 and 2017 were included in this review. The creditable databases were searched for relevant key words. The cross-sectional, experimental, and interventional investigations assessing the existence of H. pylori in the plaque, the state of plaque in gastric re-infection, the presence of co-infection between the oral cavity and stomach, the influence of triple therapy on the plaque, and the impression of periodontal treatments on prevention of recurrent gastric H. pylori infection were included.
    RESULTS
     Science metric review of literature demonstrated considerable disagreement with no definite conclusion. Due to the existing diversity in methodology and population groups, wide variation in results was reported.
    CONCLUSION
     Further homogenous studies are required to more clarify the “H. pylori in dental plaque” theory.
    Keywords: Helicobacter pylori, dental plaque, Gastritis
  • مرجان نیک بخت زاده، وحید شیبانی*، غلامرضا سپهری، مسعود ناظری، خدیجه اسماعیل پور، محمدرضا آفرینش
    مقدمه

    علایم اختلال بعد از تروما (Posttraumatic stress disorder = PTSD) و درد می تواند به طور مکرر به دنبال یک حادثه تروماتیکی در فرد بروز نماید. اگر چه در شرایط استرس حاد، ادراک درد به طور قابل توجهی در اثر استرس پوشیده می شود، مطالعات کمی در رابطه با تغییرات ادراک درد در شرایط استرس ناشی از PTSD در صورت وجود دارد. در مطالعه حاضر، تغییرات درد حاد و آلودینیای ناحیه صورت موش صحرایی در مدل حیوانی  PTSDمورد بررسی قرار می گیرد.

    روش ها

    در این مطالعه تجربی از 95 سر موش صحرایی نر نژاد ویستار استفاده شد. موش های صحرایی به دو دسته کنترل و استرس تقسیم بندی شدند. بعد از ایجاد   PTSDبه روش(Single Prolonged Stress)  SPS در گروه استرس، و تایید ایجاد SPS به روش ارزیابی رفتاری ماز بعلاوه و سنجش کورتیکوسترون پلاسما، درد حاد و آلودینیا در ناحیه صورت توسط آزمون مالش چشم (Eye wiping) و وون فری مورد ارزیابی قرار گرفت.

    یافته ها

     تعداد ورود و زمان سپری شده در بازوی باز ماز بعلاوه در گروه استرس نسبت به گروه کنترل کاهش معنی داری نشان داد (0/05 < p). میزان کورتیکوسترون بعد از تزریق دگزامتازون، در گروه استرس + دگزامتازون درمقایسه با گروه کنترل + دگزامتازون به طور معنی داری کاهش یافت (0/05 < p). تعداد مالش چشم در گروه استرس، در مقایسه با گروه کنترل کاهش  معنی داری نشان داد (0/01 < p). آستانه پاسخ در اثر اعمال فیلامان های وون فری، در صورت موش صحرایی گروه استرس، در مقایسه با گروه  کنترل افزایش معنی دار نشان داد (0/01 < p).

    نتیجه گیری

     این مطالعه نشان داد که در شرایط استرس ناشی از SPS، ادراک درد حاد و آلودینیای ناحیه صورت کاهش می یابد. احتمالا، افزایش اپیوییدهای اندوژن درشرایط PTSD، سبب کاهش ادراک درد  ناحیه صورت موش های صحرایی می شود.

    کلید واژگان: PTSD, درد حاد و آلودینیا, صورت موش صحرایی, کورتیکوسترون, ماز بعلاوه
    Marjan Nikbakht Zadeh, Vahid Sheibani*, Gholamreza Sepehri, Masoud Nazeri, Khadije Esmail Pour, MohammadReza Afarinesh
    Introduction

    Post-traumatic stress disorder (PTSD) symptoms and pain can be appeared repeatedly following traumatic events. Although in acute stress condition, pain perception significantly covered by stress, few studies have discussed the changes in pain perception in a PTSD stress conditioning. In the present study, changes of facial acute pain and allodynia have been investigated in an animal model of PTSD.

    Methods

    Male Wistar rats were divided to two groups as control and under stress. PTSD was induced by single prolonged stress (SPS) method and confirmed by elevated plus maze (EPM) and rats plasma corticostrone levels. Acute facial pain and allodynia were evaluated by the eye wiping test and von frey test in the experimental groups.

    Results

    SPS rats spent less time and made a fewer entries into the open arms of EPM (p < 0.05). The corticostrone level was significantly decreased in Stress + DEXA group compared to the Control + DEXA (p < 0.05). The number of eye wiping was significantly decreased in SPS-induced rats compared to the control (p < 0.001). The response threshold of applying von frey filament in face of SPS-induced rats was significantly increased compared to the control (p < 0.001).

    Conclusion

    Acute pain perception and allodynia of face area of rats was reduced in SPS-induced animals. Increased endogenous opioids in PTSD condition may lead to this observation.

    Keywords: Acute pain, Allodynia, Corticostrone, Elevated plus maze, PTSD, Rat face
  • Masoud Nazeri, Mohammad Shabani, Shahrnaz Parsania, Leila Golchin, Moazamehosadat Razavinasab, Fatemeh Abareghi, Moein Kermani
    Background

    Stress can alter response to nociception. Under certain circumstances stress enhances nociception, a phenomenon which is called stress‑induced hyperalgesia (SIH). While nociception has been studied in this paradigm, possible alterations occurring in passive avoidance (PA) learning after exposing rats to this type of stress has not been studied before.

    Materials and Methods

    In the current study, we evaluated the effect of chronic swim stress (FS) or sham swim (SS) on nociception in both spinal (tail‑flick) and supraspinal (53.5 ̊C hot‑pate) levels. Furthermore, PA task was performed to see whether chronic swim stress changes PA learning or not. Mobility of rats and anxiety‑like behavior were assessed using open‑field test (OFT).

    Results

    Supraspinal pain response was altered by swim stress (hot‑plate test). PA learning was impaired by swim stress, rats in SS group did not show such impairments. Rats in the FS group showed increased mobility (rearing, velocity, total distant moved (TDM) and decreased anxiety‑like behavior (time spent in center and grooming) compared to SS rats.

    Conclusions

    This study demonstrated the simultaneous impairment of PA and nociception under chronic swim stress, whether this is simply a co‑occurrence or not is of special interest. This finding may implicate a possible role for limbic structures, though this hypothesis should be studied by experimental lesions in different areas of rat brain to assess their possible role in the pathophysiology of SIH

    Keywords: Nociception, passive avoidance learning, stress‑induced hyperalgesia, swim stress
  • Touraj Vaezi, Jahanshah Salehinejad, Mansoreh Darijani, Hamed Ebrahimnejad, Javad Darijani, Masoud Nazeri, Mahtab Vakili
    Calcifying odontogenic cyst (COC), Central odontogenic fibroma (COF) and aggressive central giant cell granuloma (CGCG) are rare pathologic diseases affecting the jaws. While the Co-existence of two of them is reported in the literature, existence of all three conditions in one patient is an extremely rare entity. In the present report, initial biopsy revealed fibrosarcoma, therefore mandibular resection was performed for the subject. Sectional Histopathologic evaluation revealed the co-existence of three conditions through histopathologic evaluation. This report emphasizes the importance of precise microscopical evaluation of jaw lesions and thorough sectional examination of the lesions to reach the precise diagnosis. Treatment modalities and follow-up radiographs are also provided to help clinicians manage these entities.
    Keywords: Calcifying odontogenic cyst, Central giant cell granuloma, Central odontogenic fibroma, combined lesion, surgical management
  • شیما سام*، مسعود ناظری، عباس سام، فروزان رفیعی، آرش شهروان
    این مطالعه به منظور بررسی و مقایسه ی میزان استرس، افسردگی و هوش هیجانی در دانشجویان رشته های علوم پزشکی و دانشجویان رشته های فنی- مهندسی انجام شد. این مطالعه ی مقطعی بر روی 383 نفر از دانشجویان سال های اول تا سوم رشته های پزشکی، دندان پزشکی، پرستاری، مهندسی کامپیوتر، الکترونیک و مواد که به صورت تصادفی طبقه بندی شده انتخاب شده بودند (از هر رشته 60 نفر)، انجام شد. جهت سنجش از پرسش نامه های هوش هیجانی شوته (33SSEIT-)، استرس کسب شده (10PSS-) و افسردگی بک (21BDI-) استفاده شد و داده ها با استفاده از آزمون های معنادار بودن ضریب همبستگی پیرسون، مجذور کای و t گروه های مستقل، مورد تجزیه و تحلیل قرار گرفت. میانگین نمره ی هوش هیجانی در کل جمعیت مورد مطالعه 4/ 13±4/ 121، میانگین نمره ی استرس تجربه شده 8/ 6±5/ 17، و میانگین نمره ی افسردگی آزمون بک 7/ 8±28/ 10 به دست آمد. همبستگی منفی و معنادار بین هوش هیجانی و استرس (r = - 0.417، p = 0.01) و هوش هیجانی و افسردگی (r = -0.372، p = 0.01) مشاهده شد. بین دانشجویان رشته های مختلف از لحاظ هوش هیجانی، استرس و افسردگی اختلاف معناداری مشاهده نشد (p> 0.05). همچنین رابطه ی بین سن، جنس، وضعیت تاهل و سطح تحصیلات با هوش هیجانی، استرس و افسردگی نیز معنادار نبود (p> 0.05). می توان نتیجه گرفت که هوش هیجانی در کاهش استرس و افسردگی دانشجویان موثر است و تفاوتی در این مولفه ها بین دانشجویان علوم پزشکی و فنی- مهندسی وجود ندارد.
    کلید واژگان: هوش هیجانی, استرس, افسردگی, دانشجویان علوم پزشکی, دانشجویان فنی, مهندسی
    Shima Sam, Masoud Nazeri, Abbas Sam, Forouzan Rafie, Arash Shahravan
    The present study was performed on propose of assessment and comparison of stress, depression and emotional intelligence among medical students and engineering students This cross-sectional study was done on 383 student in 1st to 3rd year students of medicine, dentistry, nursing, computer science, electronics, and materials, 60 members of each subject were selected and classified randomly. The emotional intelligence questionnaire (SSEIT-33), the obtained stress (PSS-10) and the Beck Depression Inventory (BDI-21) were used to assess the significance of the data which was examined and analized utilizing Pearson's correlation coefficient, chi-square, and t are independent groups, were analyzed. The mean score of emotional intelligence in the general population was121.4±13.4, the mean score of experienced strees score was 17.5±6.8, and the mean score of Beck depression test was 10.28±8.7. In addition, a significant negative correlation was observed between emotional intelligence and stress (r = - 0.417, p = 0.01) and between emotional intelligence and depression(r = -0.372, p = 0.01). There was no significant difference between students of different disciplines in terms of emotional intelligence, stress and depression(p> 0.05); moreover, the relationship between age, gender, marital status and education level of emotional intelligence, stress and depression was not significant (p> 0.05). In concultion, the results showed that emotional intelligence was effective to lessen stress and depression, and the difference regarding to these technical components was not noticed between medical students and engineering students.. Therefore, the promotion of emotional intelligence in medical and engineering students appears to be necessary.
    Keywords: Emotional Intelligence, Stress, Depression, Medical Sciences Students, Engineering Students
  • عصمت راهی، شهلا محبان، محمد شعبانی*، محمدرضا بانشی، اعظم رستگاری، محمدرضا بهرامپور، مسعود ناظری
    سابقه و هدف
    پزشکان زن بویژه متخصصان زنان و اطفال، از عوارض ناشی از سزارین آگاهی بیشتری دارند. با توجه به نقش متخصصان زنان و اطفال در افزایش آگاهی مادران، مراقبتهای دوران بارداری، انجام آزمایشات غربالگری، تولد نوزاد سالم و ارتباط نوع زایمان بر ضریب رشد هوشی نوزادان، این مطالعه به منظور بررسی شیوع سزارین در پزشکان زن خصوصا متخصصین زنان و اطفال در مقایسه با سایر متخصصان انجام شد.
    مواد و روش ها
    این مطالعه مقطعی در سال 1391 بر روی 179 نفر پزشک متخصص زن که حداقل دارای یک فرزند زنده و سالم بودند، انجام شد. اطلاعا با استفاده از پرسشنامه ای شامل: نوع مدرک و تخصص، نوع زایمان و علت (پزشکی، غیرپزشکی)، سن مادر در هنگام تولد هر نوزاد، نوع استخدام (هیئت علمی و غیر هیئت علمی) جمع آوری و مورد بررسی قرار گرفت.
    یافته ها
    بیش از 60 درصد افراد به دلایل غیر پزشکی از روش سزارین جهت زایمان استفاده کردند. سزارین در متخصصین اطفال و زنان 2/ 36 برابر سایر متخصصین بود و با افزایش تعداد فرزندان شانس انجام سزارین 42 درصد کاهش و با افزایش سن شانس سزارین از 25 تا 30 درصد افزایش پیدا کرد. متخصصین زنان و اطفال 2/ 4 برابر بیش از سایرین به زایمان به صورت سزارین تمایل داشتند. تفاوت آماری معنی داری از لحاظ وضعیت استخدام بین اعضاء هیئت علمی و سایرین برای انتخاب روش زایمان وجود نداشت.
    نتیجه گیری
    نتایج مطالعه نشان داد که میل به سزارین به دلایل غیر پزشکی در دو گروه متخصصین زنان و اطفال بیشتر از سایرین می باشد. بنابراین به نظر می رسد این دو گروه هدف نمی توانند به عنوان الگویی جهت کاستن از انتخاب سزارین جهت زایمان مورد توجه قرار گیرند.
    کلید واژگان: سزارین, سن مادر, متخصص زنان, متخصص اطفال
    Esmat Rahi, Shahla Moheban, Mohammad Shabani *, Mohammadreza Baneshi, Aazam Rastegari, Mohammadreza Bahrampour, Masoud Nazeri
    Background And Objective
    Female physicians, especially gynecologists and pediatricians, have a comprehensive knowledge of the complications caused by Cesarean section. These specialists play a pivotal role in raising maternal awareness, providing prenatal care, performing screening tests and delivery of healthy infants. Given the significant correlation between the type of delivery and the mental development of neonates, this study aimed to compare the rate of Cesarean section among female gynecologists and pediatricians with other specialists.
    Methods
    This cross-sectional study was conducted on 179 female physicians with at least one living, healthy child in 2012. Data were collected using questionnaires including the degree of specialty, mode of delivery and the reason (medical or non-medical), maternal age at birth time and the employment status of the subjects.
    Findings
    In total, more than 60% of the studied specialists chose Cesarean delivery for non-medical reasons, and the rate of C-section among gynecologists and pediatricians was 2.36 times higher compared to other specialists. In addition, the possibility of C-section declined to 42% with the increasing number of childbirths, and the risk of C-section increased between 25-30% with the age. Gynecologists and pediatricians preferred C-section 4.2 times than other specialists, and no significant differences were observed between the employment status of the subjects (faculty members vs. Others) and the choice of delivery mode.
    Conclusion
    According to the results of this study, the preference of C-section for non-medical reasons was noticeably higher among gynecologists and pediatricians compared to other specialists. Therefore, these two groups could not be considered as a proper model to reduce the rate of C-section.
    Keywords: Cesarean Delivery, Maternal Age, Gynecologist, Pediatrician
  • Maryam Raoof, Atieh Sadr, Farahnaz Nazari*, Sara Amanpour, Masoud Nazeri, Saeedeh Sadr, Sedigheh Farzaneh, Jahangir Haghani, Maryam Rad
    Introduction

    Effective post-operative pain management is one of the problems following root canal treatment. Nonsteroidal anti-inflammatory drugs (NSAIDs) are the most commonly prescribed analgesics in endodontics. The aim of this study was to evaluate the effectiveness of naproxen in controlling pain following root canal treatment in teeth with irreversible pulpitis.

    Materials and methods

    This triple-blinded clinical trial was performed on 68 patients admitted to dental school for root canal treatment (RCT). Patients were randomly allocated to treatment or placebo groups. After performing RCT, the patients received naproxen (275 mg every 12 hours for 48 hours) or placebo. Patients were instructed to complete a VAS pain score at 6, 12, 24, 48 and 72 h after single visit root canal treatment. Patients were classified as having no, mild, moderate, or severe pain. Data were analyzed via SPSS software using chi-square and t-test.

    Results

    Although there was a significant difference between naproxen prescription compared with placebo in 6 and 72 hour intervals, the effect of naproxen in controlling post endodontic pain in all intervals was more than placebo. In addition, the duration of pain was shorter in the subjects receiving naproxen.

    Conclusion

    Based on the results of the present study, naproxen could be suggested to control post endodontic pain in patients with irreversible pulpitis.

    Keywords: Root canal treatment, Postoperative pain, Naproxen, Irreversible pulpitis
  • Mohammad Shabani, Peyman Yaghmaei, Hossein Mohtashamipour, Moazamehosadat Razavinasab, Masoud Nazeri *
    Introduction
    Sub-chronic swim stress is known to induce a prolonged hyperalgesia, which is mediated through NMDA and opioid systems. Nitric oxide is a soluble gas, which acts as a retrograde messenger that modulates the release of mentioned neurotransmitters. It is also involved in nociception and memory. The aim of this study was to evaluate the role of NO pathway in nociception and memory disruption induced by sub-chronic swim stress.
    Methods
    Three sessions forced swimming stress protocols were applied to rats. Before each swimming session, pretreatment with L-NAME (10 mg/kg, i.p.), L-Arginine (10 mg/kg, i.p.) or saline was made. Passive avoidance learning, nociception and anxiety-like behavior were evaluated 24 hours after last swim stress session.
    Results
    Results showed that step through latency was decreased after swim stress and it could be inhibited by pretreatment with L-NAME. Swim stress increased anxiety-like behavior in the open field test, which could be inhibited by pretreatment with L-NAME and L-Arginine. Reduced thermal threshold was observed in the nociceptive measurement after swim stress. Pretreatment with L-NAME could reverse this reduced threshold.
    Conclusion
    The results of this study indicate that sub-chronic swim stress impairs nociception and passive avoidance learning. It seems that NO pathway have a modulatory role in these alterations.
    Keywords: Nitric Oxide, Hyperalgesia, Psychophysical stress, Memory impairment
  • Shahrnaz Parsania, Mohammad Shabani, Kasra Moazzami, Moazamehosadat Razavinasab, Mohammad Hassan Larizadeh, Masoud Nazeri, Majid Asadi, Shekaari, Moein Kermani
    Objective(s)
    Neurotoxicity of anticancer drugs complicates treatment of cancer patients. Vinblastine (VBL) is reported to induce motor and cognitive impairments in patients receiving chronic low-dose regimen.
    Materials And Methods
    The effects of VBL treatment on motor, learning and memory functions of male and female Wistar rats were studied by behavioral related tests. Animals were given chronic intraperitoneal injections of VBL (0.2 mg/kg/week for 5 weeks) from postnatal day 23 to 52. Motor function was evaluated using grasping test and balancing was evaluated by the rotarod. Spatial learning and memory and anxiety-like behavior were determined using Morris water maze (MWM) task and open field test, respectively.
    Results
    Administration of VBL caused severe damage to motor and balance function of male rats in comparison to female rats treated with VBL and rats treated with saline. Memory and locomotion were affected in both male and female rats compared with saline treated rats, while a sex difference was also observed in these parameters; male rats showed more impairment compared with female ones. Both male and female rats showed cognitive impairments in MWM task and no sex differences were observed in these functions.
    Conclusion
    Results revealed that VBL is a potent neurotoxic agent and despite the profound effect of VBL on motor and cognitive functions, it seems that male rats are more susceptible to motor deficits induced by VBL.
    Keywords: Anticancer, Learning, memory, Motor function, Vinblastine
  • Hassan Azhdari-Zarmehri, Mohammad Mohammad-Zadeh *, Masoud Feridoni, Masoud Nazeri
    Introduction
    Formalin injection induces nociceptive bahaviour in phase I and II, with a quiescent phase between them. While active inhibitory mechanisms are proposed to be responsible for initiation of interphase, the exact mechanisms which lead to termination of nociceptive response in phase II are not clear yet. Phase II is a consequence of peripheral and central sensitization processes, which can lead to termination of the noxious stimuli responses; 45-60 minutes after formalin injection via possible recruitment of active inhibitory mechanisms which we have investigated in this study.
    Methods
    To test our hypothesis, in the first set of experiments, we evaluated nociceptive response after two consecutive injection of formalin (50μL, 2%), with intervals of 5 or 60 minutes. In the next set, formalin tests were carried out in companion with injection of Naloxone Hydrochloride, a non-selective antagonist of opioid receptors, pre-formalin injection and 30 and 45 minutes post formalin injection.
    Results
    While normal nociceptive behaviour was observed in the group receiving one injection of formalin, a diminished response was observed in phases I and II of those receiving consequent injection of formalin, 60 minute after first injection. While second injection of formalin, 5 minute after first injection, had no effect. Administration of naloxone (1mg/kg) decreased nociception in phase 2A; but had no effect on delayed termination of formalin test.
    Discussion
    The results of this study suggest the existence of an active inhibitory mechanism, other than the endogenous opioids, that is responsible for termination of nociceptive behaviour at the end of formalin test.
    Keywords: Formalin Test, Nociception, Naloxone
سامانه نویسندگان
  • مسعود ناظری
    مسعود ناظری
    دانشجو دکتری دانشگاه تهران
  • مسعود ناظری
    مسعود ناظری
    (1398) دکتری مدیریت دولتی- رفتار سازمانی، خوارزمی
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