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فهرست مطالب نویسنده:

mohammad hosein ebrahimzadeh

  • نفیسه جیرفتی، علی مرادی، فرشید باقری، محمدحسین ابراهیم زاده*

    استفاده از اکسترنال فیکساتور (پین) در جراحی های ارتوپدی موارد استفاده ی زیادی در زمینه-ی تروما دارد. ابجاد عفونت ناشی از کاربرد ایمپلنت ها، به دلیل شل شدن پین فرو رفته در استخوان به دلیل تشکیل بیوفیلم ناشی از حضور باکتری ها برروی پین موفقیت کاربرد بالینی ایمپلنت ها را به شدت تحت تاثیر قرار داده است. یکی از روش های موثر در کاهش این عفونت، پوشش دهی سطح پین ها با مواد آنتی باکتریال است. بر این اساس در مطالعه پیش رو، سنتز پودر هیدروکسی آپاتیت حاوی یون های نقره و فلوراید (Ag-FHA) به روش سل ژل مورد بررسی قرار گرفت و خواص ساختاری و میکروبی آن ارزیابی گردید. تصاویر به دست آمده از میکروسکوپ الکترونی تاییدکننده سایز نانو در ذرات پودر Ag-FHA می باشد. بر اساس نتایج تست Mapping پراکندگی همگن ذرات در پودر سنتز شده بخوبی انجام گرفته است و نتایج تست FTIR نشان می دهد هیچ گونه گروه عاملی ناخواسته یا ناخالصی در ساختار آپاتیت-های سنتز شده وجود ندارد. آنالیز XRD نشان می دهد در دمای حدودی 300 تا 350 درجه سانتی گراد تبدیل فاز آمورف به فاز کریستالی در ساختار HAاتفاق افتاده است و در دمای حدود 500 درجه سانتی گراد تشکیل فاز HA مشاده می گردد که در دمای حدود 600 افزایش یافته و تکمیل شده است. تست آنتی باکتریال پودر سنتز شده (حداقل غلظت مهارکندگی باکتری (MIC) و حداقل غلظت باکتری کشی ((MBC) در برابر میکروارگانیسم های استافیلوکوکوس اوریوس و اشریشیاکلی به عنوان باکتری های رایج در عفونت های بعد از جراجی های ارتوپدی، مورد بررسی قرار گرفت. نتایح نشان داد پودرهای حاوی Ag 0.2-FHAمی توانند بصورت مطلوبی در برابر رشد هر دو گونه باکتری مقاومت کنند.

    کلید واژگان: استافیلوکوکوس اورئوس, هیدروکسی آپاتیت, اشریشیا کلی, فیکساتور خارجی, نقره
    Nafiseh Jirofti, Ali Moradi, Farshid Bagheri, Mohammad Hosein Ebrahimzadeh *

    The external fixators (pins) have many applications in orthopedic surgeries in the field of trauma. The success of clinical applications of external fixators has decreased due to their infection after orthopedic surgery. Meanwhile, the loosening of the pin embedded in the bone occurs due to the presence of bacteria and the formation of biofilm on the pin, and this infection will progress to the joint surface of the bone and the pin. Among the different techniques to improve the bone-pin interface in external fixation, coating the pins with antibacterial materials proved to be the most effective. Accordingly, the present study has focused on synthesis by sol gel method, structural, and antibacterial evaluations of Ag-FHA structure. The FESEM images and Mapping analysis confirmed the nano-scale size and homogeneous dispersion of particles in the Ag-FHA structure, respectively. In addition, the FTIR results indicated the hydroxyapatite formation in obtained structure. The XRD analysis has shown that the conversion of the amorphous phase to the crystalline phase occurred in all structures at a temperature of about 300 to 350 ° C , and the formation of the HA phase is increased and completed at 600 ° C. The antibacterial study was done by minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) determination. The obtained results showed that the Ag 0.2-FHA could significantly inhibit the growth of Staphylococcus aureus and Escherichia coli.

    Keywords: Staphylococcus aureus, Hydroxyapatite, Escherichia coli, External fixator, Silver
  • شکیلا شاهی، نفیسه جیرفتی، محمدحسین ابراهیم زاده، مهرنوش نخعی، علی مرادی*

    فیکساتورها به عنوان روشی جراحی در درمان شکستگی ها هستند و به دو دسته داخلی و خارجی تقسیم می شوند. یکی از معایب استفاده از آن ها ایجاد عفونت در سطح پین است که در راستای آن شل شدن پین در سطح مشترک بین استخوان و پین اتفاق می افتد. استفاده از عناصر طبیعی با خاصیت آنتی باکتریال جهت پوشش دهی ایمپلنت ها در حوزه ارتوپدی توجه زیادی را به خود جلب کرده اند. در این راستا، استفاده از پوشش های زیست سازگار و زیست فعال HAبا خاصیت آنتی باکتریال بر روی سطح پین جهت کاهش عفونت در جراحی های ارتوپدی مطرح می شود. مقاله حاضر، رایج ترین عناصر با خاصیت آنتی باکتریال که می توانند جهت کارایی بالینی بهینه تر در ساختارHA بارگذاری شوند، را مورد بررسی قرار می دهد. جایگزینی یون ها مانند مس، نقره، منیزیم، استرانسیم، زینک، سیلیکون، فلوراید در یک شبکه آپاتیت می تواند ضمن ایحاد خواص آنتی باکتریال، باعث تحریک استخوان سازی در محل شکستگی گردد. بررسی مطالعات انجام شده نشان می دهد نقره دارای خاصیت استحکام و خاصیت آنتی باکتریال مطلوبی است و مقاومت به خوردگی و تخلخل بالای مس از مزایای این عنصر می باشند. همچنین منیزیم با زیست سازگاری و زیست تخریب پذیری مطلوب و روی با مشخصه افزایش تراکم و قدرت در استخوان، همچنین سیلیکون و فلویور با قابلیت انعطاف پذیری بالا، خواص مکانیکی مطلوب، ومقاومت به خوردگی معرفی می گردند. از بین عناصر یاد شده نقره و فلوراید به دلیل داشتن خواص آنتی باکتریال مطلوب تر و تحریک بهینه استخوان سازی می توانند کاندیدای مناسب-تری جهت بارگذاری در ساختار HA با هدف کاربرد پوشش دهی با خاصیت آنتی-باکتریال در ایمپلنت های ارتوپدی باشند.

    کلید واژگان: زیست سازگاری, آنتی باکتریال, عفونت, هیدروکسی آپاتیت, نقره
    Shakila Shahi, Nafiseh Jirofti, Mohammad Hosein Ebrahimzadeh, Mehrnoush Nakhaei, Ali Moradi *

    Fixators are the basic equipment for fractures that are divided into two categories, internal and external. The success of clinical applications of external fixators has decreased due to their infection after orthopedic surgery. Meanwhile, the loosening of the pin embedded in the bone occurs due to the presence of bacteria and the formation of biofilm on the pin, and this infection will progress to the joint surface of the bone and the pin. Natural elements with antibacterial activity attract much attention as a coating on implants surface in orthopedics surgery. This article reviewed common elements with antibacterial activity that can be loaded into the HA structure as a coating for improving their clinical efficiency. Substitution ions such as copper, silver, magnesium, strontium, zinc, silicon, and fluoride in an appetite network can stimulate bone formation at the fracture site. In this article, common antibacterial ions in the form of loading -HA have been investigated as coating orthopedic fixators. good strength and antibacterial activity presented for silver, and corrosion resistance and high porosity are advantages of copper. Also, magnesium with favorable biocompatibility and biodegradability, zinc with high strength, and silicon and fluorine with high flexibility, favorable mechanical properties, and corrosion resistance are introduced. Among the mentioned elements, silver and fluoride, due to having more favorable antibacterial activity and excellent bone regeneration, can be more suitable candidates for loading in the HA structure with the application of the coating on the orthopedic surface.

    Keywords: Biocompatibility, Antibacterial, Infection, Hydroxyapatite, Silver
  • عادل ابراهیم پور، محمد رازی، سید محمدجواد مرتضوی، محمدحسین ابراهیم زاده، روشنک مرادی، فرساد بیگلری*، سید سعید خبیری، محمد فکور، محمدعلی سازگاری، فرشید باقری
    مقدمه

    برای بهبود سطح آموزش دستیاران ارتوپدی و بهبود خدمت رسانی به بیماران در سیستم آموزشی درمانی ایران، در قدم اول لازم است که اطلاعاتی در مورد وضعیت کنونی آموزش علمی، عملی و پژوهشی دستیاران به دست آید.

    روش ها

    در این طرح پژوهشی در وهله اول بررسی کریکولوم آموزشی اجرایی در 14 مرکزاز 6 دانشگاه علوم پزشکی مختلف انجام شد و در وهله بعد به بررسی منابع انسانی، زیرساخت ها، امکانات و تجهیزات اتاق عمل، نتایج آموزشی و پژوهشی و اجرای منظم آزمون های عملی و عملکرد دستیاران در سال های رزیدنتی پرداختیم. تمامی موارد فوق در قالب پرسشنامه ای کامل و جامع طراحی شد. این پرسشنامه از جانب انجمن علمی ارتوپدی ایران، توسط سایت فرم افزار به صورت لینک برای روسای بخش های این مراکز ارسال و پاسخ ها بررسی شد. ارتباط امکانات و تجهیزات با میزان قبولی در امتحان بورد تخصصی ارتوپدی در این پرسشنامه سنجیده شد.

    یافته ها

    در بین مراکز بررسی شده تنها 20 درصد به طور مشخص معیارهای کوریکولوم آموزشی ایران را در تمام زمینه های منابع انسانی، آموزشی و پژوهشی کامل رعایت کرده بودند.

    نتیجه گیری

    مراکز آموزشی ارتوپدی ایران باید در فواصل منظم روش های نوین آموزشی مراکز معتبر جهانی و کوریکولوم کشوری را بررسی کنند. همچنین سیستم های نظارتی نیز باید به طور مستمر بر روند آموزش دستیاران تخصصی ارتوپدی نظارت کنند تا استاندارد سازی و یکسان سازی خدمات، تجهیزات و برنامه آموزشی بخش های داخل کشور به نحو مطلوب انجام شود.

    کلید واژگان: رزیدنت, کوریکولوم, آموزش, برنامه درسی, آموزش آکادمیک, ارتوپدی
    Adel Ebrahimpour, Mohammad Razi, SM Javad Mortazavi, MohammadHosein Ebrahimzadeh, Roshanak Moradi, Farsad Biglari *, Seyyed Saeed Khabiri, Mohammad Fakoor, MohammadAli Sazegari, Farshid Bagheri
    Background

    To improve the education of orthopaedic residents and enhance patient care in the Iran's healthcare system, it is necessary to gather information about the current status of scientific, practical, and research-based education for residents.

    Methods

    The research project initially focused on examining the executive curriculum in 14 centers affiliated with 6 different medical universities. Subsequently, an investigation was conducted into human resources, infrastructure, operating room facilities, educational and research outcomes, as well as the regular implementation of practical examinations to evaluate the performance of residents during their residency years. All the aforementioned aspects were covered using a comprehensive questionnaire, which was distributed via the "Formafzar.com" website as a link to the heads of departments in these centers by the Iranian Orthopaedic Association. The relationship between facilities and equipment and passing the future specialized orthopaedic board examination was also evaluated.

    Results

    Among the examined centers, only 20% adhered to the criteria of Iran educational curriculum in all aspects of human resources, education, and research.

    Conclusion

    a regular evaluation of teaching methods used by international centers and the national curriculum is necessary for orthopaedic training centers in Iran. Additionally, regulatory systems should monitor the training process of orthopaedic residents to standardize services, equipment, and educational programs in the country.

    Keywords: Residency, Education, Curriculum, Academic training, Orthopaedics
  • سید هادی سید حسینیان، فرشید باقری*، رضا پور علی، احسان واحدی، علی بیرجندی نژاد، محمدحسین ابراهیم زاده
    پیش زمینه

    جراحی آرترودز (Arthrodesis) مچ پا یکی از جراحی های اصلی برای درمان آرتروز پیشرفته مفصل مچ پا است. تکنیک های مختلفی برای درمان آرترودز مچ پا وجود دارد و هر تکنیک دارای مزایا و معایب منحصر به فرد خود است. هدف از این مطالعه، بررسی نتایج درمانی آرترودز مچ پا با استفاده از دو تکنیک بود که از میان تکنیک های مختلف انتخاب شد.

    مواد و روش ها

    سوابق پزشکی بیمارانی که از دی ماه 1393 تا دی ماه 1398 به دلیل آرترودز مچ پا در بیمارستان بستری شده و توسط یک جراح تحت درمان قرار گرفته بودند، بررسی شد. بیماران پس از میانگین دوره پیگیری 19 ماهه برای ارزیابی مجدد به بیمارستان فراخوانده شدند. نتایج عملکردی با استفاده از سیستم امتیازدهی مورد تایید AOFAS (American Orthopedic Foot and Ankle Society Score) برای مچ پا، پرسشنامه پای منچستر آکسفورد MOXFQ (Manchester-Oxford Foot Questionnaire) و مقیاس دیداری درد VAS (visual analog scale)، ارزیابی شد. داده های جمع آوری شده در فهرست از پیش طراحی شده، ثبت شد و با استفاده از نرم افزار SPSS مورد تجزیه و تحلیل قرار گرفت.

    نتایج

    در مجموع 32 بیمار، 18 مرد و 14 زن با میانگین سنی 7/46 سال وارد مطالعه شدند. 6/67 درصد این بیماران، سابقه شکستگی مچ پا داشتند. 24 بیمار یعنی 75 درصد از بیماران با روش قدامی و باقی بیماران (25 درصد) با روش جانبی تحت جراحی قرار گرفته بودند. رایج ترین ابزار برای درمان آرترودز استفاده همزمان از پلیت و پیچ در 18 بیمار (56%) بود. جوش خوردگی در 28 بیمار (5/87%) در 1/11 هفته پس از جراحی رخ داد. در ارزیابی این بیماران پس از جراحی، امتیازدهی AOFAS به طور معنی داری افزایش یافت و امتیازات MOXFQ و VAS به طور معنی داری کاهش یافت (p<0.001 برای هر کدام). سن بالا و میخ داخل استخوانی با زمان طولانی جوش خوردگی همبستگی داشت (p<0.05). روش های جراحی (اعم از قدامی یا جانبی) هیچ ارتباطی با امتیازات AOFAS، MOXFQ و VAS نداشتند. عدم جوش خوردن در 4 بیمار (5/12%) و عفونت عمیق در 3 بیمار (3/9%) پس از آرترودز مچ پا گزارش شد.

    نتیجه گیری

    نتایج مطالعه نشان داد که این نوع جراحی می تواند درد و عملکرد بیماران را با عوارض نسبتا پایین پس از عمل، بهبود بخشد.

    کلید واژگان: مچ پا, آرتروز, آرترودز, ارزیابی نتایج
    Sayyed-Hadi Sayyed-Hosseinian, Farshid Bagheri *, Reza Pourali, Ehsan Vahedi, Ali Birjandinejad, MohammadHosein Ebrahimzadeh
    Background

    Ankle arthrodesis is one of the major surgeries for the treatment of advanced osteoarthritis of the ankle joint. There are various techniques available for ankle arthrodesis and each technique has unique advantages and disadvantages. The aim of the present study was to evaluate the results of ankle arthrodesis with two this different approaches.

    Methods

    The medical records of the patients who were admitted for ankle arthrodesis and treated by a single surgeon from January 2015 to January 2020 were reviewed. The patients were recalled for re-evaluation after a mean follow-up of 19 months. Functional outcomes were assessed using validated AOFAS Ankle-Hind foot score, Manchester-Oxford Foot Questionnaire (MOXFQ) and visual analog scale (VAS) score for pain. The collected data were recorded in a pre-designed checklist and then analyzed using SPSS software.

    Results

    A total of 32 patients, 18 men and 14 women with a mean age of 46.7 years were included in the study. 67.6% had history of ankle fractures. Anterior approach was used in 24 patients, 75%, and the rest of the patients had surgery with lateral approach (25%). The most common instrument for arthrodesis was concomitant use of plate and screws in 18 patients (56%). Union occurred in 28 patients (87.5%) within 11.1 weeks after the surgery. The AOFAS score increased significantly and MOXFQ and VAS scores decreased significantly following the surgery (p<0.001 for each). Advanced age and intramedullary nail were related to prolonged time to union (p<0.05). Surgical approaches (either anterior or lateral) had no association with AOFAS, MOXFQ, and VAS scores. Non-union was seen in 4 patients (12.5%) and deep infection in 3 patients (9.3%) after ankle arthrodesis.

    Conclusion

    The study results showed that, this surgery could improve patients’ pain and function with relatively low post-operative complications.

    Keywords: Ankle, osteoarthritis, Arthrodesis, outcome assessment
  • مهرنوش نخعی، نفیسه جیرفتی، علی مرادی *، محمدحسین ابراهیم زاده
    پیش زمینه

     غلاف تاندون فلکسور در انگشتان یک تونل فیبروسیوسی با خط سینوویال با تراکم سگمنتال بافت فیبری است که پولی نامیده می شود. پولی نوع A با ساختاری حلقوی، از مهمترین پولی ها در انگشتان دست است. روش رایج در درمان و ترمیم تاندون آسیب دیده، بازسازی دو مرحله ای آن با استفاده از سیلیکون راد می باشد که به دلیل زمان بازتوانی بلند مدت و تمایل به چسبندگی تاندون ترمیم شده به تونل فیبری- استخوانی اطرافش، همواره با مشکلاتی همراه بوده است. استفاده از پولی مصنوعی برای ترمیم آسیب های تاخیری تاندون در یک مرحله باعث می شود که ترمیم دو مرحله ای تاندون فلکسور در ناحیه یک و دو، در یک مرحله انجام شود و نیازی به استفاده از سلیکون راد و عوارض و هزینه آن نخواهد بود. در این راستا، در پژوهش پیش رو، داربست های نانوالیافی پلی یورتان (PU) برای ساخت پولی مصنوعی طراحی شده اند.

    مواد و روش ها

     الکتروریسی برای ساخت داربست های نانوالیافی مورد استفاده قرار گرفت و خواص ساختاری و مکانیکی آنها مورد ارزیابی قرار گرفته است.

    یافته ها

     خواص ساختاری داربست های نانوالیافی نشان دهنده نزدیکی سایز نانوالیاف پلی یورتان با الیاف پروتیینی و پلی ساکاریدی در ماتریس برون سلولی، Extracellular Matrix (ECM) می باشد. نتایج حاصل از طیف سنجی تبدیل فوریه مادون قرمز، Fourier Transform Infrared (FTIR) تایید کننده حضور گروه های عاملی Polyurethane (PU) و عدم حضور واکنش های ناخواسته است. میزان تنش (54/0±19/3) و مدول یانگ (39/0±20/1) در ساختارهای نانوالیافی پلی یورتان شباهت نزدیکی به خواص مکانیکی در پولی های طبیعی را نشان می دهند.

    نتیجه گیری

     نتایج به دست آمده نشان می دهد داربست های نانوالیافی پلی یورتان می توانند به عنوان کاندیدای مناسبی جهت ساخت پولی مصنوعی در آسیب تاندون فلکسور مطرح شوند.

    کلید واژگان: پولی, تاندون فلکسور, مدول یانگ, نانوالیاف, پلی یورتان
    Mehrnoush Nakhaei, Nafiseh Jirofti, Ali Moradi *, MohammadHosein Ebrahimzadeh
    Background

     Pulley is a synovial tissue that attaches the flexor tendons to the dorsal portions of the fibro-osseous tunnel near the tendon attachment. Pulley type A with ring structure is one of the most important pulleys in fingers. Two-stage reconstruction by silicon is the common treatment in damaged tendon which has long recovery time and the tendency of the repaired tendon to adhere to the fibrous-bone tunnel around it. Accordingly, the one-stage reconstruction by synthetic pulley is a promising approach to resolve the mentioned problems.

    Methods

     In the present research, the polyurethane (PU) nanofiber scaffolds have been designed for synthetic pulley applications, and their mechanical and structural properties have been evaluated.

    Results

     The structural properties of nanofiber scaffolds show similar properties to protein and polysaccharide fibers in the extracellular matrix (ECM). The Fourier transform infrared spectroscopy (FTIR) results confirmed the functional groups of PU without any unwanted reactions. The amount of stress (3.19 ± 0.54) and Young's modulus (1.20 ± 0.39) in PU nanofiber scaffolds show similar mechanical properties to natural pulley.

    Conclusion

     The obtained results showed that the PU nanofibers scaffolds can be proposed as a suitable candidate for fabrication of synthetic pulley in flexor tendon injuries.

    Keywords: Pulley, flexor tendon, Young's modulus, Nanofibers, Polyurethane
  • مهرنوش نخعی، نفیسه جیرفتی، محمدحسین ابراهیم زاده، علی مرادی*

    بروز عفونت بعنوان یکی از عوارض جراحی های ارتوپدی، عواقب بدی برای بیمار و سیستم مراقبت های بهداشتی به دنبال دارد. به طور کلی از بین رفتن بافت استخوان به دلیل تشکیل لایه ی زیستی روی فیکساتور کاشته شده رخ می دهد و منجر به شکسته-شدن ایمپلنت عفونی و متعاقبا ایجاد التهاب موضعی و تخریب استخوان می گردد. در این مقاله مروری، تاثیر هیدروکسی آپاتیت (HA) پوشش دهی شده بوسیله ی آنتی بیوتیک های سیستمیک، به دلیل فعالیت زیستی موثر و ساختار شیمیایی مناسب در درمان های حوزه ی ارتوپد مورد بررسی قرار داده می شود. ونکومایسین، جنتامایسین و توبرامابسین آنتی بیوتیک های رایج در جراحی های ارتوپدی می باشند. استفاده از آنتی بیوتیک های ذکر شده به صورتی تزریقی نمی تواند بصورت موثری عفونت ایحاد شده بر روی سطح ایمپلنت را کاهش داده و یا درمان کند. در این راستا استفاده از پوشش های آنتی بیوتیک دار بر روی سطح ایمپلنت می تواند روش موثرتری در کنترل عفونت بعد از جراحی های ارتوپدی باشد. محققان نشان می دهند که ایمپلنت های پوشش داده شده با هیدروکسی آپاتیت بارگذاری شده با آنتی بیوتیک ها، انتخاب مناسبی برای کاهش زمان بهبودی، کاهش بروز درد و رشد همزمان استخوان جدید روی ایمپلنت هستند. مطالعات نشان دادند که فعالیت ضدباکتریایی و کاربردهای بالینی ایمپلنت های پوشش دهی شده با هیدروکسی آپاتیت به همراه آنتی بیوتیک ها، در جراحی های ارتوپدی بسیار موثر می باشند. تمامی آنتی بیوتیک-های مورد بررسی نتایج مطلوبی را در خصوص درمان عفونت از خود نشان دادند و ونکومایسین با توجه به میزان زمان رهایش طولانی تر خود و کمترین میزان سمیت در مقایسه با آنتی بیوتیک های دیگر، می تواند به عنوان دارویی با نتایح بالینی موفق تر در بارگذاری در هیدروکسی آپاتیت به منظور پوشش دهی شانزهای ارتوپدی مورد استفاده قرار گیرد.

    کلید واژگان: هیدروکسی آپاتیت, آنتی بیوتیک, فعالیت آنتی باکتریال, ونکومایسین
    Mehrnoush Nakhaei, Nafiseh Jirofti, MohammadHosein Ebrahimzadeh, Ali Moradi *

    Occurrence of infection is one of the complications of orthopedic surgery, which has bad consequences for the patient and the health care system. Loosing of bone tissue occurs due to the formation of a biological layer on the implant fixator, and it leads to the breaking of the infected implant and subsequently to local inflammation and bone destruction. In this review article, the effect of hydroxyapatite-loaded with antibiotics, due to its effective biological activity and appropriate chemical structure in orthopedic treatments is investigated. Vancomycin, gentamicin and tobramabicin are common antibiotics in orthopedic surgeries. The use of these mentioned antibiotics by injection cannot effectively reduce or treat the infection on the surface of the implant. In this regard, the use of antibiotic coatings on the implant surface can be a more effective method in controlling infection after orthopedic surgeries. Studies show that the implants coated with hydroxyapatite-loaded with antibiotics are a suitable choice for useful applications such as reducing recovery time, reducing pain and simultaneous growth of new bone on the implant. Researchers showed that the antibacterial activity and clinical applications of implants coated with hydroxyapatite along with antibiotics are very effective in orthopedic surgeries. All the examined antibiotics showed favorable results in the treatment of infection, and Vancomycin, due to its longer release time and the lowest level of toxicity compared to other antibiotics, can be used as a medicine. With more successful clinical results, it can be used in hydroxyapatite loading in order to cover the orthopedic schanzes

    Keywords: Hydroxyapatite, Antibiotic, Antibacterial activity, Vancomycin
  • Sayyed Hadi Sayyed Hosseinian, Farshid Bagheri *, MohammadHosein Ebrahimzadeh, Ali Moradi, Sogol Golshan
    Background

    Several devices have been described for fixation of displaced medial malleolar fractures. Fullythreaded cancellous screws engaging the bone may provide advantages compared to partially threaded screws.This study was designed to compare the clinical results of fully and partially threaded 4 millimeter cancellousscrews in fixation of medial malleolar fractures.

    Methods

    In a randomized clinical trial study 44 patients with displaced closed medial malleolar fractures wererandomly divided into two groups. Two fully threaded four millimeter cancellous screws were used for fracturestabilization (FT group) in the first group, while, the second group was operated by use of two partially threaded fourmillimeter cancellous screws (PT group). The clinical outcomes and complications were compared in two groups atone year follow up.

    Results

    Nineteen patients in FT group and 21 in PT group were present at final follow up. Nonunion was notdeveloped in either group but two cases (9%) of delayed union occurred in PT group. The rate of postoperativeinfection and symptomatic hardware were not statistically different. Functional assessment using AOFAS, MOXFQand VAS scores showed no significant difference between the two groups.

    Conclusion

    Both fully and partially threaded 4 mm cancellous screws can be considered as acceptable devices forthe fixation of medial malleolar fractures with good and comparable clinical results.Level of evidence: I

    Keywords: Ankle fracture, Fracture fixation, Medial malleolus, screw
  • پیش زمینه

    مطالعه ی رفتار خزشی یک سری از نانوکامپوزیت های زیست تخریب پذیر که به عنوان تجهیزات قابل کاشت در داخل بدن استفاده می شوند، همچون پیچ های زیستی یک فاکتور حیاتی است. در این مقاله به منظور بررسی بیشتر رفتارهای خزشی و خزشی-بازیابی این مواد زیستی، از چند مدل کلاسیک جهت مدل سازی این رفتارها استفاده شد.

    روش

    رفتار خزشی و بازیابی نانوکامپوزیت های متشکل از آمیخته پلیمری زیست تخریب پذیر پلی دال لاکتید (PDLLA) و پلی کاپرولاکترون (PCL) تقویت شده با مقادیر مختلف 1 و3 و6 درصد وزنی از نانوذرات شیشه زیست فعال (m-BGn) مدل شدند. چندین مدل تیوری همچون مدل توانی فایندلی، مدل برگر و مدل ویبول استفاده شدند تا ارتباط بین نحوه ی توزیع و پراکندگی فاز m-BGn بر رفتار خزشی و بازیابی نهایی نانوکامپوزیت دریافت شود.

    نتایج

    مدل فایندلی تایید کرد که کمترین مقدار پارامتر  Aو بیشترین مقدار پارامتر A) n دامنه کرنش خزشی گذرا و n  پارامتر توانی زمان است(.متعلق به نمونه با بیشترین مدول الاستیک است و نانو کامپوزیت ها در مقایسه با آمیخته PCL/PDLLA، دارای مقدار A کمتر و n بیشتر هستند که می توان به تاثیر بازدارندگی m-BGn در کرنش خزشی مرتبط دانست. علاوه بر این نتایج مدل برگر نشان داد که همه پارامترهای ویسکوالاستیک و ویسکوپلاستیک برای نانوکامپوزیت ها از مقادیر بیشتری نسبت به آمیخته های PDLLA/PCL خالص برخوردارند. این بدین معناست که افزودن نانوذرات شیشه زیست فعال که منجر به کاهش کرنش خزشی می شود، سبب افزایش مقادیر پیش بینی کننده مدل برگر شده که این مقادیر با   رابطه عکس دارد. علاوه براین مدل توزیع ویبول تصدیق می کند که افزودن m-BGn به داخل آمیخته های پلیمری PDLLA/PCL منجر به کاهش مقادیر بازیابی کرنشی ویسکوالاستیک می گردد. این اثر نیز می تواند ناشی از تاثیر بازدارندگی m-BGn بر رفتار بازیابی خزشی نانوکامپوزیت ها باشد.

    نتیجه گیری

    نتایج به دست آمده از مدل سازی رفتار خزش-بازیابی آمیخته های PDLLA/PCL و نانوکامپوزیت های آن ثابت کرد که نانوذرات استحکام بخش شیشه زیست فعال یک نقش ممانعت کنندگی مناسب در رفتارهای خزشی و بازیابی خزشی بازی می کند.

    کلید واژگان: آمیخته PDLLA, PCL, نانوذرات شیشه زیست فعال, رفتارهای خزشی و خزشی- بازیابی, مدلسازی ریاضی
    Javad Esmaeilzadeh*, saeed hesaraki, mohammad, mehdi Hadavi, mohammad hosein Ebrahimzadeh
    Background

    To study the creep behavior for a series of biodegradable nanocomposites, which are used as implantable devices in the body such as bioscrews, is a crucial factor. In the current paper, we are investigating these biomaterials -short-time creep and creep recover manners- in several classic models.

    Methods

    The creep and creep recovery behaviors of nanocomposites composed of biodegradable polymer blends, poly (D/L) lactic acid (PDLLA) and polycaprolactone (PCL) reinforced with three different contents of 1, 3 and 6 percent weight percentage (Full name?)% bioactive glass nanoparticles (m-BGn) were modeled. Several theoretical models including Findley power law, Burgers and Weibull models were used to establish the relations between m-BGn dispersion and final creep and creep-recovery behaviors of nanocomposites.

    Results

    The Findley power law model confirmed that the lowest ‘A’ and highest ‘n’ parameters ( A is the amplitude of the transient creep strain and n is the time exponent) belong to the sample with the highest young modulus and the nanocomposites compared to PDLLA/PCL  blends have the lower ‘A’ and higher ‘n’ which can be related to retardation effect of m-BGn on creep strains. Besides, the burgers model results illustrated that all viscoelastic and viscoplastic parameters for nanocomposites possess higher values than those of the neat PDLLA/PCL blend. It means that the addition of glass nanoparticles leads to decrease creep strain , increasing the Burgers model prediction values which have inverse trend with . Moreover, the weibull distribution model results acknowledge that the introduction of m-BGn into PDLLA/PCL polymeric blends cause decrease  in the viscoelastic strain recovery values. This is due to hindering effects of m-BGn on creep recovery behavior of nanocomposites.

    Conclusion

    The results obtained from modeling of creep-recovery manners of PDLLA/PCL blend and its nanocomposites approved that the bioactive glass reinforcement nanoparticles play  impeding role on creep and creep recovery behaviors..Level of evidence: I.

    Keywords: PDLLA, PCL blend, bioactive glass nanoparticles, creep, creep recovery behavior, modeling
  • Alireza Mousavian, Sayyed Hadi Sayyed Hosseinian, Omid Shahpari, Ali Mohammadi, Nafiseh Elahpour, Arezoo Orooji, Mohammad Hosein Ebrahimzadeh, Ali Moradi *
    Background
    Foot function index (FFI) is a worthy subjective patient reported outcome measures (PROM) tool forevaluation of the outcomes of medical interventions on foot and ankle. This study was conducted to assess the validityof the Persian version of the foot function index (FFI).
    Methods
    After translating the original FFI into Persian, back-translation was performed on the agreed Persian versionand the final version was established. A total of 113 Persian-speaking patients with foot and ankle problems wereenrolled in this study and were asked to fill in the FFI.
    Results
    The Cronbach’s alpha for subsections of FFI and MOXFQ was above 0.8 and 0.7, respectively, while it was0.95 and 0.93 for total FFI and MOXFQ, respectively. The ICC for all subsections of MOXFQ and FFI was above 0.7.The Pearson’s correlation coefficient for all subsections of FFI and MOXFQ was significant (P<0.01).
    Conclusion
    The Persian version of FFI is valid and reproducible in Persian speaking population.Level of evidence: IV
    Keywords: Foot function index, Persian version, Validation, Foot, ankle
  • Mohammad Hosein Ebrahimzadeh *, Ali Moradi, Hamid Farahpour Bidgoli, Batool Zarei
    Background
    the aim of this study is to evaluate the prevalence and effect of depression and anxiety on the shoulder range of motion, as well as the objective and subjective symptoms in patients suffering from frozen shoulder.
    Methods
    Between 2013 and 2014, in a cross‑sectional study, we evaluated 120 patients with idiopathic frozen shoulder. We collected the demographic data for each patient and measured shoulder range of motion in four directions in both limbs. All patients flled out visual analog scale (VAS) for pain and the disabilities of the arm, shoulder, and hand (DASH) questionnaires. Both Hamilton anxiety and depression questionnaires were flled out for each patient.
    Results
    A total of 92 patients (77%) with idiopathic frozen shoulder showed symptoms of depression, while only 32 (27%) of them experienced anxiety. Thirty‑two patients (27%) showed symptoms of both depression and anxiety. Although elevation and abduction were not affected by depression, internal and external rotations were more restricted among patients who had symptoms of depression. DASH and VAS scores were higher in patients with symptoms of depression. In terms of anxiety, only VAS and DASH were different between two groups. In multivariable analysis, DASH score was correlated with severity of both anxiety and depression symptoms.
    Conclusion
    While there is no defnitive relationship between symptoms of depression or anxiety and shoulder range of motion in patients suffering from frozen shoulder, patients who suffer from depression or anxiety experienced increased pain and limb disability.
    Keywords: Adhesive capsulitis, anxiety, DASH, depression, frozen shoulder
  • Ahmad Alizadeh *, Mohsen Mardani, Kivi, Mohammad Hosein Ebrahimzadeh, Alireza Rouhani, Keyvan Hashemi, Khashayar Saheb, Ekhtiari
    Background
    The aim of this study was to compare the therapeutic effects of four methods of ultrasound (US) alone or in combination with low-level laser therapy (LLLT) (L/US), intra (InCI), and extra (ExCI) sheath US-guided corticosteroid injection in the treatment of long head of the biceps (LHB) tendonitis.
    Methods
    In a randomized clinical trial, patients with LHB tendonitis were enrolled in four groups (US, L/US, InCI, and ExCI). Pain using visual analogue scale (VAS) and shoulder performance according to Constant-Murley score (CMS) were evaluated at five visits of before, one week, one month, three months, and one year after treatment.
    Results
    VAS and CMS scores were improved after treatment in all four groups and at all visits in comparison with before treatment. The VAS score in the one-week visit was lower in the InCI group than in all other groups, but it became similar to the score of the ExCI group after this visit and was significantly lower than the score of the US group one year after treatment. CMS was similar at all visits between InCI and ExCI. At one-week and one-month visits, significant differences were seen between the injection groups and the two other non-injection groups, but at the last visit, CMS of the InCI group was only significantly different from that of the US group.
    Conclusions
    Although intrasheath corticosteroid injection under US guidance is an effective method for the treatment of LHB tendonitis, especially in the 1st week after treatment, extra sheath injection also has acceptable results. Using L/US as a less invasive treatment could be as effective as using corticosteroid injection in long-term.
    Keywords: Biceps Tendonitis, Ultrasound, Low-Level Laser, Corticosteroid-Guided Injection
  • Mohammad Hosein Ebrahimzadeh, Farshid Bagheri *, Ali Moradi, Ali Birjandi Nejad
    Background
    Knee dislocations are uncommon (<0.5% of all dislocations); however, they may result in catastrophic outcomes secondary to their high-energy nature and neurovascular injuries.
    Objectives
    The objective of this study was to evaluate the clinical outcome of knee dislocation management. Subjects and
    Methods
    A total of 20 consecutive adult patients with knee dislocation were enrolled in this cross-sectional study between 2011 and 2014. A single knee surgeon examined all the patients for knee instability for subjective evaluation of knee function using the Lysholm Knee Questionnaire, Knee Society Score (KSS), and Short Form-36 (SF-36).
    Results
    The average Lysholm Knee Scores and KSS were 68 (range: 18–100) and 65 (range: 15–97), respectively. All domains of SF-36 among the studied patients were lower than that of the normal population. We could not find any correlation between age, body mass index, and interval between initial trauma and operation with outcome variables (Lysholm Knee Score, KSS, and SF-36 Physical Component Score, and SF-36 Mental Component Score).
    Conclusions
    The knee function after proper management of dislocation is reasonable, but prolonged course of management and multiple operations may decrease the patients' quality of life.
    Keywords: Knee dislocation, knee function, quality of life
  • Farzad Omidi-Kashani *, Ebrahim Ghayem Hasankhani, Mahmoud Tavousi, Amir Ashjazadeh, Mohammad Hosein Ebrahimzadeh
    Background
    In surgical treatment of thoracolumbar burst fractures, most authors try to lower the number of vertebrae involved during the surgery.
    Objectives
    The aim of this study was to evaluate the outcome of a medium-segment posterior spinal fixation in these patients.
    Patients and
    Methods
    We retrospectively reviewed 27 patients (18 male, 9 female) with mean age of 39.4 ± 15.0 years old in a before-and-after study. The mean follow-up period was 38.4 ± 15.6 months. We involved 2 intact above vertebrae and one intact below vertebra, inserting a pedicular screw at the fractured level and supplemented the construct with contralateral infralaminar hook. Clinical and radiologic characteristics were assessed with American spinal injury association (ASIA) scale, oswestry disability index (ODI), visual analogue scale (VAS), and plain radiography. Data analysis was carried out by SPSS version 11.5 software.
    Results
    Mean post traumatic kyphosis was 15.7° ± 3.3° that was changed to - 8.5° ± 4.3° and ° ± 4.4° at immediate and last visit after surgery, respectively. Mean loss of correction (LOC) was 9.5° ± 1.9° (P
    Conclusions
    In surgical treatment of thoracolumbar burst fractures, a medium-segment posterior spinal fixation, although cannot maintain the radiologic reduction of the fractured vertebrae efficiently, is not only associated with acceptable clinical outcome but also spare one lower intact lumbar segment and therefore recommended.
    Keywords: Spinal Fractures Instrumentation, Pedicle Screws, Spinal Fusion
  • Farshid Bagheri, Mohammad Hosein Ebrahimzadeh*, Ali Moradi, Hamid Farahpour Bidgoli
    Background
    Frozen shoulder is resulting in limb disability and reduction of quality of life but the factors associated with patients’ disability and quality of life is not clear. To assess pain, disability, the quality of life and factors associated with them in patients suffering from frozen shoulder.
    Methods
    We enrolled 120 patients (37 men and 83 women) with phase-II idiopathic frozen shoulder in our cross-sectional study. Demographic data were collected and shoulder range of motion was measured in four different directions (elevation, abduction, external and internal rotation) in both upper limbs. Patients were asked to fill out Visual Analog Scale for pain (VAS) and, Short-Form Health Survey questionnaire (SF-36) as well as Disabilities of the Arm, Shoulder and Hand (DASH) questionnaires. We asked the patients to fill out the Hamilton anxiety and depression questionnaires.
    Results
    The mean of VAS pain, DASH, PCS, and MCS scores were 69(18), 53(17), 35(8.0), and 42(10) respectively. All the domains of SF36 questionnaires where below the normal population except physical function. VAS pain score was correlated to Hamilton depression scores in both bivariate and mulivarilable analysis. DASH score were correlated to sex, age, ROM, and both Hamilton anxiety and depression scores; However, DASH score only impact with Hamilton anxiety and ROM independently. PCS is correlated to age and MCS to Hamilton depression.
    Conclusion
    Patient with frozen shoulder are more suffering from pain and disability secondary to psychiatric parameters such as depression and anxiety than demographic features or even restriction of range of motion.
    Keywords: Adhesive capsulaitis, Disability, Frozen shoulder, pain, Quality of life, Shoulder
  • Ali Moradi, Mohammad Hosein Ebrahimzadeh, Jesse Jupiter
    Radial tunnel syndrome is a disease which we should consider it in elbow and forearm pains. It is diagnosed with lateral elbow and dorsal forearm pain may radiate to the wrist and dorsum of the fingers. The disease is more prevalent in women with the age of 30 to 50 years old. It occurs by intermittent compression on the radial nerve from the radial head to the inferior border of the supinator muscle, without obvious extensor muscle weakness. Compression could happen in five different sites but the arcade of Frose is the most common area that radial nerve is compressed. To diagnosis radial tunnel syndrome, clinical examination is more important than paraclinic tests such as electrodiagnsic test and imaging studies. The exact site of the pain which can more specified by rule of nine test and weakness of the third finger and wrist extension are valuable physical exams to diagnosis. MRI studies my show muscle edema or atrophy along the distribution of the posterior interosseous nerve. Although non-surgical treatments such as rest, NSAIDs, injections and physiotherapy do not believe to have permanent relief, but it is justify undergoing them before surgery. Surgery could diminish pain and symptoms in 67 to 93 percents of patients completely.
    Keywords: Diagnosis, Radial Tunnel Syndrome, Treatment
  • Mahdi Mazloumi, Farzad Omidi, Kashani*, Mohammad Hosein Ebrahimzadeh, Hadi Makhmalbaf, Mohammad Mahdi Hoseinayee
    Background
    The prevalence of neglected developmental dysplasia of the hip (DDH) has been decreasing. Nowadays, the disease is rarely seen in walking age children. The purpose of this study is to assess the results of simultaneous osteotomy of femur and pelvic bones in such children.
    Method
    We performed a retrospective study on 30 children aged 3.8±0.9 (range: 1.5-7) years old, with DDH who underwent surgical operation in our hospital from August 2001 to September 2006. Tönnis and Severin grading systems were used to classify the radiographic status of the hip in pre- and postoperative era, respectively. Improvement in function and limp was also evaluated by the modified McKay’s classification.
    Results
    From the 30 cases, six patients excluded in the course of the study and among the remaining patients, 12 had bilateral involvement. The mean follow-up period was 7.6±0.8 (range: 5.1-11.3) years. During the last visit, radiographic status of the operated joints, according to Severin classification was as follows: Class I: 12 patients; Class II: 20 patients; Class III: 3 patients; Class IV: 1 patient; and Class VI: 1 patient.
    Conclusion
    Although through the follow-up, two hips subluxated, necrosis happened in three and one joint was re-dislocated, simultaneous femoral and innominate osteotomy in the walking age children with DDH has relatively good clinical outcomes.
    Keywords: Developmental dysplasia of the hip, Osteotomy, Radiography
  • Mohammad Hosein Ebrahimzadeh, Ali Moradi, Maysam Fathi Choghadeh, Jafar Rezazadeh, Farzad Omidi-Kashani, Ali Birjandinejad*
    Background

    Fractures of the knee account for about 6% of all trauma admissions. While its management is mostly focused on fracture treatment, it is not the only factor that defines the final outcome.

    Objectives

    This study aimed to study objective and subjective outcomes after proximal tibial versus distal femoral fractures in terms of knee instability and health-related quality of life.

    Patients and Methods

    This retrospective, cross-sectional, cohort study was carried out on 80 patients with either isolated proximal tibial (n = 42) or distal femoral (n = 38) fractures, who underwent open reduction and internal fixation. All the fractures were classified based on the Schatzker and AO classification for tibial plateau and distal femoral fractures, respectively. The patients were followed and examined by an orthopedic knee surgeon for clinical assessment of knee instability. In their last follow-up visit, these patients completed a Lysholm knee score and the short-form (SF) 36 health survey.

    Results

    Among the 42 tibial plateau fractures, 25% were classified as Schatzker type 2. Of the 38 distal femoral fractures, we did not find any type B1 or B3 fractures. The overall prevalence of anterior and posterior instability was 42% and 20%, respectively. Medial Collateral Ligament (MCL) and Lateral Collateral Ligament (LCL) injuries were detected clinically in 50% and 28%, respectively. The incidence rates of ligament injuries in tibial plateau fractures were as follows: Anterior Collateral Ligament (ACL) 26%, Posterior Collateral Ligament (PCL) 7%, MCL 24%, and LCL 14%. Medial collateral ligament injury was the most common in the Schatzker type 2 (50% of the injuries). Distal femoral fractures were associated with ACL injury in 16%, PCL in 13%, MCL in 26% and LCL in 14%. However, final knee range of motion (ROM) and function (Lysholm score) were not associated with fracture location. No statistically significant difference was observed between the two groups, except for the valgus stress test at 30°knee flexion, which was more positive in tibial fractures. All eight domains of SF-36 score in the distal femoral and proximal tibial fractures were significantly different from the normal values; however, there were no statistically significant differences between femoral and tibial fracture scores.

    Conclusions

    Although ROM is acceptable in knee joint fractures, instability is common. However, it seems that knee function and quality of life are not associated with the location of the fracture

    Keywords: knee, Knee Instability, ACL, PCL, Quality of Life
  • Ali Moradi, Mohamad Reza Soroush, Mohammad Hosein Ebrahimzadeh*
    Background

    Providing care for patients with chronic disability affects caregivers’ social lives and relationships and can lead to poor health and lower quality of life.

    Objectives

    In this study, our goal was to assess the quality of life in spouses of war veterans with bilateral lower limb amputations to find factors affecting caregivers’ quality of life.

    Patients and Methods

    In a cross-sectional study, spouses of 244 veterans with war-related bilateral lower limb amputations for at least one year were invited to participate in this study; 189 couples accepted to participate. Information about age, gender, education level, duration of time since amputation, duration of care provided by the spouses and SF-36 questionnaire for both veterans and their spouses were collected.

    Results

    The average age of spouses was 47 years and duration of care provided by spouses was 25 years. We found lower scores for general health domains in amputees’ spouses compared to the general population. Factors correlated with both Physical Component Summary (PCS) and Mental Component Summary (MCS) included the duration of care, duration of marriage, spouses’ education level and the veterans’ PCS and MCS scores. Veterans’ age, spouses’ age and the number of children only correlated with PCS. Veterans’ education level only correlated with MCS. In multivariable analysis, only spouses’ education level correlated with MCS and the veterans’ PCS only correlated with that of spouses.

    Conclusions

    The quality of life of amputees and their spouses were closely correlated; therefore, any improvement in one is likely to improve the other. In addition, lower education level should be considered as a risk factor for poorer quality of life in amputees’ spouses.

    Keywords: Quality of Life, Amputation, Lower extremity
  • Mohammad Hosein Ebrahimzadeh, Farideh Golhasani, Keshtan *, Bibi Soheila Shojaee
    Background
    Recently, investigations have indicated that caring of a chronically ill family member strongly influences the health status and the quality of life (QOL) of the caregiving family members..
    Objectives
    The purpose of this study was to examine the relationship between health-related QOL of veterans with chronic spinal cord injury and their caregiving spouses..Patients and
    Methods
    We designed a cross-sectional study including two groups; veterans with chronic spinal cord injury and their caregiving wives who were living in the city of Mashhad, Iran. The patients with spinal cord injury were veterans from the Iran-Iraq war (1980-1988). All the participants filled out the short form 36 (SF-36) health survey questionnaire. A Pearson correlation coefficient was calculated for the scales of the two groups..
    Results
    The mean age and standard deviation of veterans and their spouses were 48.5 ± 5.9 and 44.8 ± 7.2, respectively and their number of children ranged between 0-6. Our data analysis showed that there was a significant difference between the two groups in some domains of the SF-36, including PF, MH, PCS, MCS, BP and GH (P < 0.05), but there was no significant difference in RP, VT, SF and RE between the two groups..
    Conclusions
    The results indicate that a decrease in health status level of veterans, physically and mentally, can affect the health-related QOL of their caregiving spouses..
    Keywords: Spinal Cord Injury, Veterans, Caregiving, Quality of Life, Iran
  • Mohammad Hosein Ebrahimzadeh, Hadi Makhmalbaf, Ali Birjandinejad, Seyed Hosein Soltani-Moghaddas
    Background
    The Oxford Knee Score (OKS) is a short patient-reported outcome instrument that measures pain and physical activity related to knee osteoarthritis. The purpose of this study is to evaluate, construct validity and consistent reliability of the Persian version of the OKS.
    Methods
    The case series consisted of 80 patients who were clinically diagnosed with having knee osteoarthritis. All patients were requested to fill-in the Persian OKS and Short-Form 36 Health Survey (SF-36). Correlation analysis between the Persian versions of these two instruments was then carried out. The scores of the Persian SF-36 were used to evaluate convergent and divergent validity of the 12-item Persian OKS.
    Results
    From a total of 80 patients, 63 were female (79%) and the remaining 17 were male (21%) with a mean age of 52.2 years. In the present study, high Cronbach’s alpha of 0.95 confirms excellent internal consistency of the Persian OKS scale similar to previous investigations. The results confirm that the Persian version of this instrument is valid and reliable, similar to its English index and its subsequent translations in different languages.
    Conclusion
    The Persian OKS is a reliable instrument to evaluate knee function in patients with knee osteoarthritis and is a useful tool for outcome measurement in clinical research.
  • Seyed Hosein Fattahi Masoum, Ali Moradi, Mohammad Hosein Ebrahimzadeh
    A seven year-old boy with several painless masses on the ribs and shoulder was referred to our hospital. The masses were so prominent that they prevented the child’s sleep. Since the patient had been ridiculed by his friends due to the rib prominences, he had refused to attend school. After clinical and radiological evaluations, the masses were diagnosed as hereditary multiple exostoses of the shoulder and ribs. He underwent surgery for cosmetic reasons resulting in the patient’s return to a normal life.
    Keywords: Hereditary Multiple Exostosis (HME), Osteochondroma, Rib exostosis, Rib tumors
  • Mohammad Hosein Ebrahimzadeh, Ali Moradi, Mostafa Khalili Pour, Mohammad Hallaj, Moghaddam, Amir Reza Kachooei
    Background
    To explain the role of arthroscopic release in intractable frozen shoulders. We used different questionnaires and measuring tools to understand whether arthroscopic release is the superior modality to treat patients with intractable frozen shoulders.
    Methods
    Between 2007 and 2013, in a prospective study, we enrolled 80 patients (52 females and 28 males) with recalcitrant frozen shoulder, who underwent arthroscopic release at Ghaem Hospital, a tertiary referral center, in Mashhad, Iran. Before operation, all patients filled out the Disability of Arm, Shoulder and Hand (DASH), Constant,University of California Los Angeles (UCLA), ROWE and Visual Analogue Scale (VAS) for pain questionnaires. We measured the difference in range of motion between both the normal and the frozen shoulders in each patient.
    Results
    The average age of the patients was 50.8±7.1 years. In 49 patients, the right shoulder was affected and in the remaining 31 the left side was affected. Before surgery, the patients were suffering from this disease on average for 11.7±10.3 months. The average time to follow-up was 47.2±6.8 months (14 to 60 months). Diabetes mellitus (38%) and history of shoulder trauma (23%) were the most common comorbidities in our patients. We did not find any significant differences between baseline characteristics of diabetics patients with non-diabetics ones. After surgery, the average time to achieve maximum pain improvement and range of motion were 3.6±2.1 and 3.6±2 months, respectively. The VAS score, constant shoulder score, Rowe score, UCLA shoulder score, and DASH score showed significant improvement in shoulder function after surgery, and shoulder range of motion improved in all directions compared to pre-operation range of motion.
    Conclusions
    According to our results, arthroscopic release of recalcitrant frozen shoulder is a valuable modality in treating this disease. This method could decrease pain and improve both subjective and objective mid-term outcomes.
    Keywords: Frozen shoulders, arthroscopic release, recalcitrant, outcome
  • Ali Birjandi Nejad, Mohammad Hosein Ebrahimzadeh *, Ali Moradi
    Background
    Loss of motion is a well-known complication after elbow trauma and in severe cases, arthrolysis of elbow is the procedure of choice. The posterior approach might have some advantages especially in post-traumatic patients who have undergone the same surgical approach in the past..
    Objectives
    The aim of this study was to evaluate the short-term outcomes of elbow arthrolysis through posterior approach. Moreover, we assessed the effect of operation on the patients’ quality of life.. Patients and
    Methods
    During a retrospective-cohort study, the medical records of 14 patients (12 men, two women) whose range of movement had been limited post-traumatically and had undergone elbow arthrolysis with posterior approach were reviewed. Before intervention, the patients had a flexion less than 100 degrees or an extension lag of 30 degrees or more. For evaluation of the final outcomes, they were invited to participate in our study and the final range of motion, visual analogue score (VAS), disability of arm, shoulder and hand (DASH), Mayo elbow score (MES) and short form health survey (SF-36) scores were measured in the patients..
    Results
    Mean age of the participants was 28.7 years. The interval from initial injury and arthrolysis was 16 months and the patients were followed for 14 months. The mean range of motion in patients before surgery was 35.8 degrees, which was increased to a mean of 108.9 after the surgery, indicating a 73.1 degrees improvement. The means of VAS, DASH, Mayo elbow and SF-36 scores in the patients were 1.6, 34, 68 and 43, respectively. A significant inverse correlation was found between the preoperative range of motion and final range of motion..
    Conclusions
    According to our results, elbow arthrolysis through posterior approach could be an effective technique with low complications. Since the final range of motion improved significantly, it might be a valuable method in promoting the patients’ quality of life..
    Keywords: Elbow, Stiffness, Release, DASH
  • Mohammad Hosein Ebrahimzadeh, Bibi Soheyla Shojaee, Farideh Golhasani-Keshtan, Fatemeh Moharari, Amir Reza Kachooei, Asieh Sadat Fattahi
    Objective
    We were curious about the degree of anxiety and depression and their effect on the quality of life of the caregivers of veterans with spinal cord injury (SCI).
    Methods
    A convenience sample of 72 out of 120 caregiver spouses of veterans with spinal cord injury participated in our study. The Hospital Anxiety and Depression Scale (HADS) were considered as a measure of depression and anxiety. The World Health Organization Quality of Life BREF questionnaire (WHOQOL-BREF) was considered to evaluate the quality of life. To compare the caregivers, we enrolled 74 matched caregiver spouses of patients without spinal cord injury.
    Results
    The average age of the spouses was 44.7±6.5. The average time elapsed from the injury was 26.4±3.1 years. There was a significant difference in all domains of quality of life and depression between the caregivers and the control group, but there was not a significant difference in terms of anxiety. There was a negative correlation between depression and age, level of education and quality of life.
    Conclusion
    Mental care support should be implemented for veterans and their spouses in addition to the provided facilities.
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