mohammadhossein sharifi

 Cardiovascular diseases (CVDs) account for one-third of all deaths worldwide.

 In this cross-sectional study, we extracted all death records from the Electronic Death Registration System categorized as ischemic heart disease (IHD) based on age, gender, and the year of death according to ICD-10 for this cross-sectional analysis. The Fars province is situated in southern Iran with a population of about 4 million. An analysis of years of life lost (YLL) resulting from premature death from IHD was conducted using the World Health Organization’s 2015 YLL framework. The trend of the YLL rates was investigated using joinpoint regression.

 In the Fars province, IHD was the cause of 46969 deaths throughout a 16-year study period, (2004 to 2019). Among these, 26,503 (56.4%) were men. The crude death rates per 100000 population for men and women were 84.2 and 66.5, respectively. The total YLL due to premature death due to IHD, during the 16-year study period, was 287625 in male, 209665 in female. The joinpoint regression showed a declining trend in the YLL rate associated with premature death. Annual Percent Change (APC) was -0.6% (95% CI -6.9 to 6.1, P=0.851) for males and -1.5% (95% CI -5.2 to 2.2, P=0.418) for females.

 The trends of the standardized mortality rate, YLL, and crude mortality rate held steady throughout a 16-year period. Planning for comprehensive primary and secondary prevention and increasing public knowledge of IHD are necessary.

The article provides an analysis and evidence on the impact of ethical principles on individual lifestyles. Ethical principles in their moderate state are admitted and recommended in Islam.

In an analytical-descriptive method, this study examined Islamic ethical principles and clarified their impacts on people’s lifestyles. Muslims need to be aware of ethical principles to choose a way of life that is in line with their beliefs to avoid an identity crisis.

Man is in dire need of rethinking to live according to transcendental values and beliefs, particularly in the contemporary age. Islam invites humans to live based on ethical principles and harmonize their lifestyle with values and doctrines by which they can find perfection and salvation. In this respect, man is required to benefit from believing in the oneness of Almighty Allah (SWT) and the Day of Judgment as well as controlling the soul that influences people’s lifestyles. Additionally, man has to manage his/her deeds toward achieving perfection and avoiding identity crisis i.e., s/he must harmonize his beliefs with his/her lifestyle including social relations, wearing clothes, entertainment, eating habits, etc.

 This study aimed to investigate mortality and years of life lost (YLL) due to suicide and homicide in children aged 10-19 years in southern Iran from 2004 to 2019.

Study Design:

 A cross-sectional study.

 The data on all deaths due to suicide and homicide in Fars province were obtained from the population-based electronic death registration system (EDRS). Crude mortality rate and YLL were calculated. The joinpoint regression method was used to examine the trend.

 During the study period, 563 cases of suicide and 218 cases of homicide in children aged 10-19 have occurred. The total number of YLL due to suicide was 9766 in men and 6261 in women. According to the joinpoint regression analysis, the trend of YLL due to suicide was increasing in males. In other words, the annual percent change (APC) was 4.8% (95% CI 0.4 to 9.5, P=0.036). Additionally, there was a constant trend in females, and APC was 2.7% (95% CI -2.0 to 7.7, P=0.241). The number of YLL due to homicide was 4890 in males and 1294 in females. The trend of YLL due to homicide was stable in males and females. In other words, APC was -1.6% (95% CI -5.6 to -2.6, P=0.422) in males and -2.7% (95% CI -10.0 to 5.2, P=0.467) in females.

 Based on the findings of this study, the trend of mortality rate and YLL due to suicide in men has been increasing and it has been stable in women. Moreover, the trend of mortality due to homicide was stable for both males and females. Therefore, it is necessary to take preventive actions.

The objective of the article is to provide evidence on the impact of mysticism on the Islamic Republic of Iran through the figure, thought, and legacy of Imam Khomeini. To achieve this, the article discusses the relationship between the political thought of Imam Khomeini and his mystical and philosophical views on society and life.

The descriptive-analytical method is used to state the role and impact of mysticism on the Islamic Revolution by analyzing and comparing Imam Khomeini’s texts and speeches on the topic. Imam Khomeini was a devoted scholar who brought Islamic mysticism to the public realm of discussion, both within the religious seminary system and in the public arena of institutional discussions around the formation of the Islamic Republic.

Imam Khomeini revolutionized the clerical attitude towards politics and proved that religion was still relevant as an ideology capable of building a Modern society. His success in mobilizing his followers went beyond as he achieved this in a historical moment where the discourse of Westernization posed a threat to Iranians. Also, conveyed the revolutionary movement in a unique language featuring connotations of martyrdom, justice, freedom, and political and sociocultural independence. He emphasized the need to revitalize religion through the guidance of jurists and clerics while referencing the mystical traditions of Islam, which highlight its universality and transcendental importance.

Complementary Alternative Medicine (CAM) has been widely used globally, but limited data are available on the use of CAM in Cardiovascular Disease (CVD). The present study aimed to evaluate CAM use in CVD patients. The present cross-sectional study was performed in Shiraz, Iran, during the summer of 2021. Cardiovascular patients aged ≥ 18 years were included in the study. Demographic information on left ventricular ejection fraction and satisfaction with CAM utilization was collected using validated questionnaires. A total of 304 patients (194 males and 110 females) were recruited for this study. The frequency of patients identified as CAM users was 56.9% (n = 173). Patients with implanted pacemakers were less likely to use CAM than others (OR = 0.50, p = 0.031). Meanwhile, the likelihood of CAM utilization was approximately 2 and 4 times higher in the patients categorized in class I of the New York Heart Association (NYHA) functional classification compared to those in the second and third classes, respectively. Most CAM users used herbs, dietary supplements, and praying to prevent diseases, while Traditional Persian Medicine (TPM) remedies and acupuncture were more commonly used to treat acute and chronic illnesses, respectively. Praying for health, herbal therapy, and dietary supplementation were the most popular CAM types utilized by Iranian CVD patients. However, future investigations seem to be required to determine the exact physiological impacts, probable adverse effects, and long-term benefits of CAM therapies in this population.

In recent years, there has been a growing interest in Systems Thinking (ST) as a significant area of research. It has become increasingly crucial to provide a detailed overview of the ST domain and to identify the prevailing research focuses and trends within this realm. This study represents the most comprehensive and pioneering effort, using topic modeling analysis to analyze the landscape of ST research from the past to the present. The primary objective of this study was to identify the current state of research and the predominant areas of focus within articles related to ST. To achieve this research aim, a search was conducted on August 20, 2023, using the Scopus database, yielding 1400 articles. The bibliometric analysis findings of this study indicate a substantial surge in the number of publications in this field, especially since 2016, with a significant majority of these studies originating from the United States. While the research is characterized by its interdisciplinary nature, most publications fall within social science. Employing Latent Dirichlet Allocation (LDA), Non-Negative Matrix Factorization (NMF), and Bidirectional Encoder Representations (BER) Topic algorithms for topic modeling analysis, the study classified the articles into ten distinct topics. These topics encompass "comprehending and modeling complex systems," "sustainability in business," "interdisciplinary learning and problem-solving in education," "enhancing healthcare delivery," "system dynamics modeling," "engineering education," "chemistry education," "enhancing patient outcomes," "environmental sustainability," and "improving organizational performance."  The most prominent topics that represent common research areas in the field of Systems Thinking include "system dynamics modeling," "enhancing healthcare delivery," "interdisciplinary learning and problem-solving in education," "comprehending and modeling complex systems," "environmental sustainability," and "improving organizational performance". In conclusion, this study is expected to provide valuable guidance for future research in the field of Systems Thinking by aiding in identifying research interests and trends.

Despite the evidence for validity of body image pictogram (BIP) to discriminate overweight, obese, and normal individuals, there is little evidence on the probable effect of socio-demographic variables on its validity. To investigate the effects of socioeconomic status (SES), age, ethnicity, and educational level on the validity of BIP to discriminate normal weight, overweight, and obese people.

We used the Pars Cohort Study (PCS) data. Stunkard’s BIP score was used as test measure. Participants were classified as normal (body mass index [BMI]<25), overweight (BMI=25 to 29.9), and obese (BMI≥29.9) based on their BMI (kg/m2 ). Area under curve (AUC) and its 95% CI were estimated and compared. Optimal cutoff points and their sensitivity, specificity, and likelihood ratio were reported.

A total of 9232 participants with a female/male ratio of 1.03 were included. The prevalence of overweight and obesity was 37.4% and 18.2%, respectively. Regardless of socio-demographic levels, the optimal cut-points to discriminate normal BMI from overweight, and overweight from obese participants were BIP score of four and five, respectively. Estimated AUC correlated with ethnicity (P<0.001) for both genders, and with SES for females (P<0.05).

Although BIP may be a valid measure to categorize the general adult population into normal, overweight and obese, its validity depends on SES and ethnicity. BIP may be available as a proxy measure for BMI categories in socio-demographically homogeneous populations but not in heterogeneous populations.

This study was conducted to determine the mortality rate and years of life lost (YLL) due to homicide in Fars province. Study Design: This was a cross-sectional study.

All data related to deaths due to homicide in Fars province were obtained from the Populationbased Electronic Death Registration System. Crude and age-standardized mortality rate, YLL, and YLL rate data were calculated and joinpoint regression was used to examine the trend.

During 2004-2019, 2148 deaths due to homicide occurred in Fars province, and (1782 cases (83.0%) were men. The crude mortality rate in men decreased by 44.0% from 2004 to 2019, but a stable trend was observed in women. The total YLL due to homicide during these 16 years was 43 230 (1.37 per 1000 people) in men and 8931 (0.29 per 1000 people) in women. According to the joinpoint regression analysis, the 16-year trend of the YLL rate due to premature mortality in men was decreasing, and the annual percent change (APC) was -4.00% (95% confidence interval [CI]: -6.60 to -1.20, P = 0.008). However, women demonstrated stable trends in this respect, and APC was -0.50% (95% CI: -3.10 to 2.20, P = 0.704).

The crude and standardized mortality rates and the number of YLL due to homicide in the study period had a significant decreasing trend in men but a stable trend in women. To control this issue, officials and policymakers should identify the areas of homicide and control its risk factors such as economic and social issues, drug addiction, and the state of violence.

Phytoestrogen containing foods are known useful in controlling menopause symptom. Researches revealed that these foods can be useful for the health of menopausal women. Considering the importance of non-pharmacological treatments in reducing menopausal symptoms and confirming the effectiveness of phytoestrogen consumption in reducing these symptoms, this study was conducted to investigate the amount of phytoestrogen consumption and its relationship with menopausal symptoms.

This cross-sectional study was performed in 2022 on 130 middle-aged (45 to 55 years old) women living in Jahrom, Iran. Tools used in this study included a demographic questionnaire, a menopause rating scale, knowledge and attitude regarding phytoestrogen-containing foods and a 3-day food record questionnaire. Data were analyzed using SPSS software (version 24) and Pearson correlation coefficient. P<0.05 was considered statistically significant.

The mean amount of phytoestrogen consumed daily by the participants was 72.92±33.36 mg. Pearson correlation analyses indicated that the total amount of phytoestrogens consumed had an inverse and significant correlation with the psychological symptoms of menopause (p=.01, r=-0.190), but no significant relationship was found with the physical, urogenital, and total symptoms of menopause with amount of phytoestrogens consumed (p=0.11).

The consumption of phytoestrogens to some extent leads to a reduction of mental symptoms in menopausal women, but they have no effect on physical symptoms.

Like many countries, in our country schools were reopened by September2021, mainly because of massive personal and social costs due to the social distancingstrategies. With the emergence of Omicron variant, questions are raised and still not fullyanswered about the causes of a noticeable increase in pediatric ICU admissions. Currently,schools have reopened. In this retrospective study, the parents’ willingness to September 2021school reopening was investigated. We extracted data from approximately 3,700 parents. The data gathering tool wasa self-administered, semi-structured, web-based survey, which was filled by the parents fromJuly 18th, 2021 to August 3rd, 2021. Only 38.4% of parents agreed with school reopening. The most common reasonparents were concerned with, irrespective of their agreement status, was full vaccinationof students, teachers, and staff (83.6%); also, the most common concern that might haveenforced the parents to consider school reopening was lower learning achievements at homeusing the online platforms (55.6%). Furthermore, full-time online learning was still themostly preferred mode of reopening by the parents (43.48%). The agreement with school reopening was low among the parents and theirhighest concern was full vaccination of students, teachers, and staff. During the longerclosure, the impact on students will worsen; policymakers should accelerate and encouragethe vaccination of young ages, supply safety measures, and retain the trust of the communityfor school reopening.

The Mediterranean diet plays an essential role in maintaining older adults’ health and their quality of life (QOL). However, the older adults living in countries outside of the Mediterranean region face difficulties in adhering to the diet. This study aimed to investigate Mediterranean diet adherence and related factors among older women.

This descriptive-analytical study was conducted on 130 older women living in Shiraz in 2019. Samples were selected by two-stage cluster sampling from comprehensive health centers. Data were collected through face-to-face interviews using a demographic information questionnaire, Mediterranean diet adherence questionnaire, Lipad quality of life questionnaire, and two researcher-made questionnaires on nutritional attitude and nutritional knowledge. Data were analyzed by SPSS software version 25 at a significance level of 0.05.

The mean age of the elderly in the present study was 63.95 ± 3.44. According to the results, 19.2% of participants had low adherence, 66.2% had moderate adherence, and 14.6% had high adherence to the Mediterranean diet. There was a significant negative correlation between adherence to the Mediterranean diet with age (r = - 0.24, p <0.01), and diastolic blood pressure (r = - 0.31, p <0.05) and showed a significant positive correlation with education (r = 0.20, p <0.05) and QOL (r = 0.34, p <0.001).

Adherence to the Mediterranean diet in Iranian women elderly was not at a desirable level. In addition, adherence to the Mediterranean diet was correlated with the QOL of the older adults, so interventions are needed that increase adherence to the Mediterranean diet to improve the quality of life of Iranian women elderly.

Ensuring vaccine acceptance in societies is a growing challenge for healthcare systems worldwide. This study aimed to identify factors associated with vaccine acceptance rates. 

This cross-sectional study was conducted as a national web-based survey from February 9th-13th, 2021, just before the release of the COVID-19 vaccine in Shiraz, Iran. Independent variables included age, gender, occupation, history of COVID-19 infection, underlying diseases, and source of information. The willingness to be vaccinated was the dependent variable. A logistic regression analysis was performed to determine the relationship between different variables and the willingness to receive the COVID-19 vaccine. The significance level was set at less than 0.05. The data were analyzed using SPSS software version 21.

Of 2,699 healthcare respondents, 70.3% indicated a willingness to receive the COVID-19 vaccine, of whom 49.2% preferred to receive a foreign vaccine and 24.68% desired to receive an Iranian vaccine. The women were more willing to receive the vaccine (67.6%) than the men (78.2%). Based on the results of logistic regression, gender (P<0.001) and job (P=0.005) were the most important associating factors to the willingness to receive the COVID-19 vaccine.

Although the majority of participants were willing to receive the COVID-19 vaccine, 29.6% were not yet ready. Women’s healthcare providers were more hesitant to recommend the vaccine. As a result, the findings of this study can help policymakers and decision-makers in the field of health, treatment, and prevention of COVID-19 in raising the level of vaccination awareness among healthcare workers.

Little information is available about micronutrients intake in bodybuilding athletes taking supplements. This study aimed at investigating dietary supplements usage and micronutrients intake in male and female bodybuilders.

This cross-sectional study was performed among bodybuilders in bodybuilding clubs in Shiraz. Information about consumption of dietary supplements were collected using a questionnaire and Food Frequency Questionnaire (168 items) was completed to assess the micronutrients intake based on the Recommended Dietary Allowance (RDA).

The participants (n= 270) included 175 (64.8%) males (mean age: 33.6±2.5 years). In this study, 115 (65%) males and 45 (47%) females used dietary supplements. The study showed a significant difference in the rate of supplement use based on gender (P<0.000), age group (P<0.006), and level of education (P<0.001). Furthermore, bodybuilding trainers were the major source of dietary education (62.4%), while nutritionists and physicians accounted for nutritional advice to only 17.4% of the participants. Findings indicated low micronutrients (vitamin D, calcium, magnesium, and zinc) intake in male athletes based on RDA. There was also low intake of vitamin D, vitamin E, vitamin B9, calcium, iron, and magnesium in female athletes.

Prevalence of supplement use was high in male and female bodybuilders, however, they suffer from low intake of micronutrients.

Over the last decades, the prevalence of overweight (BMI > 25) and obesity (BMI > 30) is being the most important health challenge in urban populations. The relationship between obesity and the individual’s temperament has not been studied yet.

This review aimed to study the causes of obesity, especially in middle-aged people, according to the new evidence of conventional medicine and findings of Traditional Persian Medicine (TPM) physicians cited in their books. Databases including PubMed, Scopus, and Iran Medex were also searched with keywords obesity and overweight for recent evidence in conventional medicine.

Based on the traditional Persian medicine findings, dystemprament or disequilibrium in Mizaj may promote obesity in middle-aged and elderly people. The attenuation of innate heat and intrinsic moisture in middle age could increase the chance of overweight and obesity. Recent studies in modern nutrition reveal a linear relationship between diminishing the basal metabolic rate and increasing age, especially in middle age. Accordingly, cold-wet-tempered people have more efficient energy homeostasis than hot-dry-tempered people that is similar to individuals with Firmicutes gut microbiota predominance. People living in high altitudes and cold-dry climates maintain their innate heat better than people living in wet climates. It is in accordance with the increasing brown adipose tissue thermogenesis in cold exposure, which decreases the chance of obesity.

Based on traditional Persian medicine school, it is hypothesized that increasing age and diminishing innate heat besides the accumulation of phlegm (moisture) in the gastrointestinal tract of middle-aged individuals may be influential in altering gut microbiota and consequently obesity. It seems that there may be a correlation between cold/wet Mizaj and risk factors of obesity

Polypharmacy can negatively affect the life of type 2 diabetes (T2DM) patients. There is little evidence on the associated factors of, and patterns of polypharmacy among T2DM patients in developing regions. The aim of this study is to determine the population-based prevalence of polypharmacy, its associated factors, and pattern in southern Iran.

We used baseline data from the Pars Cohort Study (PCS). Age-standardized prevalence of polypharmacy and its 95% confidence interval (CI) were estimated. Association of polypharmacy with demographic and socio-economic factors, anthropometric measures, serum biomarkers, physical activity, cigarette and tobacco smoking, and multimorbidity was assessed by applying multivariable Poisson modeling. Prevalence ratio (PR) and its CI were estimated. The Anatomical Therapeutic Chemical (ATC) classification system was used for drug classification.

Totally, 874 previously diagnosed T2DM patients with a mean age of 56.3±9.2 participated in the study. The estimated agestandardized prevalence for men and women was 17.2% (CI: 12.0–22.0) and 34.1% (CI: 33.2–39.4), respectively. The prevalence of hypertension, hyperlipidemia and cardiovascular disorders among the study population was 39%, 58% and 20%, respectively. Having more than four comorbidities (PR, 3.90; CI, 2.39–6.34), central obesity (PR, 2.66; CI, 1.03–6.84), and female gender (PR, 1.49; CI, 1.14–1.97) were associated with polypharmacy. Also, 56.0% of patients and 23.0% of elder patients (>59 years old) reported using anti-diabetic agents.

Polypharmacy was low among T2DM patients. More than 75% of the elder population were not on anti-diabetic medications. Polypharmacy was higher among patients with multiple comorbidities, central obesity, lower physical activity, lower socio-economic status, younger age at diagnosis, and longer duration of T2DM.

 Public support plays a crucial in managing public health crises. Communicating with the public during a pandemic has a major role in gaining public support. Public information-seeking behaviors are the core element of epidemic communication..

 The current study aimed to investigate the Iranian information-seeking behaviors during the first three weeks of the COVID-19 pandemic in Iran.

 In this cross-sectional study, the use of web search queries to monitor the COVID-19 pandemic in Iran from December 2019 to March 1 2020, is investigated. The Iranian search queries for COVID-19 were evaluated from December 30, 2019, to March 1, 2020. Google trend reports were used to retrieve data on the number of search queries. Queries were categorized into “epidemic news”, “necessary protective equipment”, “prevention strategies”, and “treatment”. To analyze the data, segmented regression was applied. Also, the daily percent change (DPI) was estimated.

 The frequency of Google searches for COVID19-related queries first increased during the period of 18 - 23 February 2020 (DPC: 34.0; P value < 0.001), and then declined to March 1, 2020 (DPS: -3.9; P value < 0.001). The most prevalent query was “Epidemic news” (54%), followed by “necessary equipment” (33%). The frequency of these two queries increased from 18 - 23 February. "Prevention strategies" was the most common search category on March 1.

 When an epidemic begins to spread, people try to get the “latest news” and “what they need to protect themselves”.

Attention to the history of medicine (HM) has been increasing enormously among the scientific community. History of Culture and Civilization of Iran and Islam (HCCII) is taught in medical schools as a required course. However, data on medical students' level of knowledge and attitude about HM is limited. This is a cross-sectional survey conducted between 2016 and 2017. A multi-stage random cluster sampling was done in which 230 medical students were asked to fill a standardized self-administered questionnaire. Univariate statistical tests and ordinary multivariable linear regression were applied. Medical students' knowledge level was 50.8%, which is considered fair and weak. Interestingly, the knowledge score of those who attended only in HCCII course did not differ significantly from those who did not attend this course (P = 0.163). The results showed that knowledge scores were considerably greater in those who participated in related volunteer workshops than those who did not (P = 0.0001). The mean score of attitude toward HM was significantly higher in female subjects than male subjects (P = 0.028). Moreover, data indicated that attendance at the HCCII course and workshops was not associated with improvement in attitude. According to the outcomes, the authors recommend revising the content, teaching method and structure of the HCCII course curriculum.

Subsea pipelines are used to transport gas and oil around the world. Oil is transported through subsea pipelines at high pressure and high temperature to smooth the way for its flow and to prevent its solidification. The present paper assesses a pipeline located in South Pars Gas Field against lateral buckling. As more and more pipelines operate at higher temperatures (over 100°C), the likelihood of lateral buckling becomes more relevant. The uncertainty in the lateral buckling parameters of the pipeline is a source of error in determining effective axial compressive force. Uncontrolled lateral buckling can cause excessive plastic deformation of the pipeline, which can lead to localized buckling collapse or cyclic fatigue failure during operation due to multiple heat-up and cool-down cycles, if it is not properly managed. This research reports the results of a reliability analysis to study and quantify the variations of the reliability index (β) with the main parameters involved during the lateral buckling of the subsea pipelines. Uncertainty is considered in the geometric parameters of the pipeline. The probability of failure (Pf) and the reliability index (β) can be determined by the reliability methods. The First-Order Reliability Method (FORM), the Second-Order Reliability Method (SORM) and the sampling method are the three main methods used here to determine Pf and β. The results show that the pipelines, in the case of lateral buckling and corrosion, will be in safe condition for up to 30 years after construction.

Vitamin D has been linked to health conditions and many serious diseases including cardiovascular, diabetes, and cancer. This study was conducted to determine the correlation between vitamin Dwith diet quality, sun exposure, physical activity, sociodemographic, and anthropometrics indices. In a cross-sectional study, 180 subjects (90 males and 90 females) aged from 14 to 57 years were enrolled. A questionnaire was used to collect sociodemographic and anthropometric data, physical activity and food intake information. The correlation between serum vitamin D with these variables was analyzed. Significant difference was noted between two genders regarding age, weight, body mass index, waist circumference, job, income, physical activity, LDL, HDL, TG, and cholesterol. Low quality diets denoted to a mean global score of 47±6.3 and 46±6.4 in male and females, respectively. No significant difference was found between diet quality, calcium intake (1310±734 mg), and vitamin D intake (1.8±1.5 mg) with serum vitamin D level. Further analysis revealed that there was a significant positive correlation between cholesterol and saturated fat intake and serum vitamin D. Between two genders, the correlation between physical activity (p<0.005), sitting time(p<0.04), and income(p<0.04) with serum vitamin D level was significant. Based on significant correlation between serum vitamin D level, with cholesterol, saturated fat intake, physical activity and income, we can conclude that physical activity has correlation with a favorable vitamin D status.

Following Myocardial Infarction (MI) and percutaneous coronary intervention (PCI), the modification of cardiovascular risk factors and inflammation can improve MI progression and PCI outcomes. Up to now, no certain conclusions have been drawn regarding the effect of therapeutic lifestyle change (TLC) diet and a combination of Q10 plus L-carnitine (LC) supplementation on inflammatory biomarkers of In-Stent Restenosis (ISR), lipid profile, and Left ventricular ejection fraction (LVEF).
This study aimed to evaluate the effects of TLC diet and Q10 plus LC supplementation on inflammatory biomarkers of ISR, lipid profile, and LVEF following MI and PCI.
This single-blind randomized controlled trial was conducted on 128 subjects. After randomization for treatment allocation, the subjects were divided into the study groups through block randomization. The MI patients were admitted to 2 hospitals, namely Al-Zahra and Kowsar (Shiraz, Iran), between April 2015 and May 2016. The patients were divided into 4 groups receiving TLC diet (A), oral Q10 150 mg/d and LC 1200 mg/d (B), a combination of LC plus Q10 and TLC diet (C), and the routine care (D). This study evaluated Interleukin-6 (IL-6) and high sensitive C-reactive protein (hs-CRP) as inflammatory biomarkers of ISR, lipid profile, and LVEF in 128 patients with MI undergoing PCI before and 3 months after the intervention.
The results showed a significant decrease in hs-CRP in groups B (11.8 ± 4.3 to 2.0 ± 1 mg/L) and C (11.7±3.9 to 1.3±1.1 mg/L) (P An adjuvant therapy with TLC diet and supplementation with Q10 and LC seems to be required for secondary prevention following MI and PCI. TLC diet and Q10 plus LC appeared to be effective in inflammatory biomarkers of ISR as well as LDL reduction.

Myocardial infarction (MI) has a deleterious effect on quality of life (QoL), which can affect cardiac prognosis after MI. Thus, new strategies have to be identified for improving the QoL. To our knowledge, no studies have been conducted on the impact of therapeutic lifestyle change (TLC) diet and L-carnitine plus Q10 supplementation on QoL after MI.
The study aimed to measure 128 MI patients’ QoL using MacNew QoL questionnaire (global scales and physical, emotional, and social subscales) before and 3 months after the intervention. The patients were divided into 4 groups. Group A received TLC diet, group B orally received Q10 150 mg/d and L-carnitine 1200 mg/d, and group C received a combination of carnitine plus Q10 and TLC diet. Finally, group D, as the control group, only underwent the routine care.
The results showed a significant increase in MacNew questionnaire’s physical, emotional, and social subscales in the four groups after the intervention. The results of within-group analysis showed that the physical and emotional subscales changed significantly (P Both TLC diet and supplementation with Q10 and L- carnitine had a positive effect on the physical and emotional subscales of MacNew questionnaire and may improve post-MI prognosis. Based on the results, combination of Q10 plus L-carnitine and TLC die can be a potential intervention for improving QoL and secondary prevention.

Herein, Compact-Testing (CT ) and Charpy V-Notch (CVN) testing have been done on four Friction-Stir-Processed (FSPed) samples: BM (Base-Metal), FS (FSPed-Sample), FN5 (FSP Nano-ZrO2-coated/560 rpm rotational speed) and FN9 (FSP Nano-ZrO2-coated/900 rpm), to investigate the KIC and the dominant parameters on it for St 37 steel. Experiments are also surveyed and validated by ABAQUS. Results showed the greatest KIC value for BM (CT: 110.40 /CVN: 98.72 MPa√m) and the least for FN9 (CT: 72.20/CVN: 60.08 MPa√m). FSP caused brittle behavior but not as much as FSP Nano-coating. The calculation of CT samples was done in Gerson theory by using of LEFM formulas. Investigations showed more reliability for CVN obtained results. The KIC and ductile fracture decreased after FSP for both CVN and CT.

Unfortunately, in the books Sahih-e Bokhari and Sahih-e Moslem there exist some narrations about The Holy Prophet wich by no means have agreement with the Quran and the creditable narrations of Fariqayn. These insulting narrations claim that his majesty has been under the infhuence of magic and fantasy, and in some other flagrant remarks have introduced him a forgetful and foul-mouthed one who muttered imprecation, and cursed Mulims and believers and always tortured them. The present essay studies and criticizes these false and insulting narrations