mohsen nemati

The dietary pattern in clinical practice has been considered in weight loss, lifestyle, and quality of life, which can lead to weight loss and affect lifestyle and quality of life. The aim of this study was to investigate the role of dietary pattern in predicting students' weight, lifestyle and quality of life.

The research method is descriptive-correlational and the statistical population is all students of Mohaghegh Ardabili University in the academic year of 2016-2017. The sample size is considered 30 students selected randomly from the statistical population. To collect data, the Quality of Life Questionnaire (IRQOL), Health Promotion Lifestyle Questionnaire, and Nutrition Table were used, and SPSS 22 software was used to analyze the data. Pearson correlation and regression correlation tests were also used to analyze the data.

The results showed that there is a significant correlation between dietary pattern and weight, lifestyle and quality of life (r=0.258, sig = 0.027, r = 0.057, sig = 0.000, and r=0.677, sig= 0.012 respectively).

The finding shows that the food pattern component can predict 60% of weight, but cannot be a good predictor of lifestyle and quality of life due to the insignificance of regression model.

Ulcerative colitis (UC) and Crohn’s disease (CD) are two major types of inflammatory bowel diseases (IBDs). Toll‑like receptors (TLRs) are expressed in the innate immune system compartments, in charge of identifying a wide range of microorganisms. The aim of the present study was to evaluate the expression of TLR‑2, ‑7, and ‑8 in peripheral blood mononuclear cells (PBMC) of UC patients as a novel non‑invasive primary inflammation sensor for monitoring the clinical course of UC candidates.

In this cross‑sectional study, total RNA was extracted from the PBMC of 42 UC patients along with 20 healthy donors. The mRNA levels of TLR‑2, ‑7, and ‑8 were assessed using the quantitative real‑time polymerase chain (qRT‑PCR) reaction.

The present research study demonstrated no significant changes in TLR‑2 mRNA expression in UC patients in comparison with the control group (P = 0.1264), whereas significant elevation (P = 0.0008) was distinguished in the TLR‑7 expression of UC participants specifically during the remission course compared with healthy donors and flareup patients (P = 0.0004 and P = 0.0063, respectively). The last selected TLR, TLR‑8 was not shown remarkable changes either between UC patients and the control group or between clinical courses of the disease.

Here, among three nominated TLRs for predicting UC patients, TLR‑7 was potentially selected according to the significant difference in mRNA expression in flareup UC patients and control donors. TLR‑7 could be used as a novel non‑invasive biomarker for monitoring UC patients in the active course of the disease.

Old world cutaneous leishmaniasis (CL) is known as a self-healing cutaneous parasitic infection. Host immunity has a fundamental role in the course of this infection. This study was designed to investigate the relationship between nutritional status and vitamin A intake with the clinical course of CL.

Overall, 250 patients with CL attending a dermatology clinic in Imam Reza Hospital Mashhad, Iran, were enrolled from Apr 2011 to Aug 2012. For data gathering, a semi-quantitative 302-item food frequency questionnaire was utilized. They received routine treatment protocols for leishmaniasis and 1 year of follow-up

As for the 149 patients who completed the study, a deficiency of macro and micronutrients, particularly vitamin A, was significantly related to a chronic clinical disease course.

Imbalanced or insufficient nutritional intake including vitamin A deficiency, may influence the clinical course of CL.

Colorectal Cancer (CRC) as a hetrogenetic disease is the second most common cancer in developed countries. More than 10% of CRC is hereditary, including the syndromes HNPCC and FAP. MSH2 gene is located on chromosome 2 (p21) and involves 16 Exons. MSH2 is a protein with a part in the remedial process of MMR following DNA assimilation. MSH2 is linked to MSH6 or MSH3 and constitutes the complexes MutSα and MutSβ, which oddly identifies small and big insertion/deletion pairs. The present study employs HRMA techniques to trace deletion (mutation) of GTG in the exon12 MSH2 gene. This study mainly aims at both examining applicability and potency of HRMA in detecting GTG deletions and determining the frequencies of such deletions in homozygous and heterozygous modes in large intestinal cancer cases with respect to the control group. To this end, 50 cases of colorectal cancer and 50 normal intestines were examined. First, genomic DNA was extracted from cancerous paraffin-embedded tissues and then it was examined using HRM techniques and determining direct sequence and frequency of GTG deletion. The controls employed included 96 GTG sequence in wild-type mode and 93 GTG in mutant mode, the equal ratio thereof was used for heterozygous mode of this position. The results showed that HRMA technique has a potential to differentiate deletion and insertion of pairs in homozygous and heterozygous modes regarding their melting point differences. Furthermore, GTG deletion frequency of cancerous cases was found to be significantly more than that of healthy people

Food insecurity is one of the categories that has a serious impact on nutritional status. Intelligence quotient is an indicator of one's efficacy. Yet, limited studies have been conducted about food security status and socioeconomic factors associated with children's Intelligence quotient (IQ). The current study aimed to investigate the relationship of household food security status and some socioeconomic factors with children Intelligence quotient (IQ) in Mashhad.
In this descriptive cross-sectional study, 18-item USDA food security questionnaire, 200 children in the food secure group and 200 children in the food insecure group were included. The members of each group were matched 1 to 1 in terms of age and gender..Children’s age group was 4-6 years old, 18-item Food Security (USDA) and General information Questionnaires were completed through interview with mothers. The relationship between qualitative and quantitative variables with Intelligence quotient (IQ) was determined by Chi-square, T-independent and one-way ANOVA.
The mean scores of verbal, performance and total IQs in food insecure group without hunger were respectively 98.75±13.24, 102.94±12.96 and 100.84±11.04, which were lower than mean of children's IQ in the food secure group (p Food security is effective on Intelligence quotient (IQ) through its impact on nutrition and as a stress factor that affects the entire family.

Long-term delivery is an important significant issue which is associated with mortality and fetal and maternal disorders. Based on the previous studies, consumption of dates affects uterine contractions and duration of delivery processes. This study aimed to study the effect of date consumption in late pregnancy on the duration of delivery processes in nulliparous women in 2013.
This randomized clinical trial was conducted among 182 nulliparous women 18–35 years who presented to OmAlBanin Hospital in Mashhad in 2013. The comparison has been made between 91 pregnant women who consumed 70–76 g dates daily from the 37th week of pregnancy and 91 pregnant women who did not consume dates. Data collection tool was a questionnaire and a checklist of daily dates’ intake. Data were analyzed using the Statistical Package for the Social Sciences software and statistical tests – chi-square and Mann–Whitney test, and P value The average length of active phase (P = 0.0001), length of second phase (P = 0.0001), and third phase (P = 0.004) in two groups had statistically significant difference. The average length of the second phase (P = 0.03) and the third phase (P = 0.02) in case of spontaneous start of delivery in the intervention group was significantly lower than the control group. Use of oxytocin to accelerate delivery had a significant difference between the two groups (P According to the results of this study, consuming dates in late pregnancy was effective in decreasing length of labor processes and reduced the need of oxytocin for labor acceleration. Thus, it is recommended to consume dates in women without contraindications.

Aim and Cervical ripening before the onset of labor is an important factor for the prediction of delivery mode, and is directly associated with vaginal delivery. The search for a safe, inexpensive, and easy method of cervical ripening is of great significance. Few studies have focused on the effect of date fruit on uterine contractions and cervical ripening. Therefore, the purpose of this study was to determine the effect of late pregnancy consumption of date fruit on cervical ripening in nulliparous women. This randomized clinical trial was performed on 210 women with a singleton pregnancy, cephalic presentation, and gestational age of 37-38 weeks. The study was conducted at Omolbanin Hospital, Mashhad, Iran in 2013. The subjects were randomly assigned into two groups of 105 women (experimental and control groups). Since the 37th week of gestation, the experimental group consumed date fruit (70 to 75 gr per day) until the onset of labor pain, and the control group received routine care. Data were collected using demographic questionnaires, fetal movement record form, and the checklist related to daily consumption of date fruit. Data analysis was performed using SPSS version 14, and Chi-square, t student, and Mann-Whitney test. P-value less than 0.05 was considered statistically significant. The mean Bishop score at admission was higher in the experimental group (7.67 ± 2.28), compared to the control group (5.12 ± 2.77) (P <0.001). Mean cervical dilatation at admission was 4.05 ± 1.63 cm in the experimental group and 2.97 ± 4.63 cm in the control group (p <0/05). Also the success rate of labor induction was higher in the experimental group compared to the control group (P= 0.006). Mean cervical dilatation was higher in women consuming date fruit, compared to the non-consuming group. Since date fruit is full of energy and nutrients, it is recommended for pregnant women to help with cervical ripening, particularly in the last weeks of gestation.

Background and The precocious puberty in girls can have some adverse effects such as growth stoppage and subsequent short stature in comparison with predicted final adult height. GnRH agonists are now considered the treatment of choice for CPP. One of the side effects of these drugs is increased appetite and consequent obesity. During puberty a progressive reduction in the level of ghrelin has been reported. This study was aimed to assess the obesity and its relationship with ghrelin in girls with true precocious puberty treated with GnRH agonists. A sample of 20 consecutive girls with true precocious puberty was selected for this prospective observational study. They received 3.75 mg intramuscular GnRH every four weeks. Height, weight, body mass index, waist circumference, Tanner stage, body fat and serum ghrelin, were measured in the time of enterance to study and during follow up visits. The follow-up visits were carried out after 6 and 12 months. Mean age of the studied 19 child was 87.5 ± 10.1. Height and weight increased significantly after 6 and 12 months, P-value<0.01. The ghrelin level and body fat percentage demonstrated no significant change during the 12 months follow-up, P-value>0.05. There were not any significant relationships between neither ghrelin and BMI nor ghrelin and body fat percentage, P-value>0.1. It seems that treatment with GnRHa is effective. More importantly patients with increased BMI may need appropriate dietary consultation to accomplish their weight control during the course of the treatment.

Healthy Eating Index (HEI) was first developed to assess and monitor nutritional status of Americans by the United States Department of Agriculture (USDA) in 1989. HEI is one of the scoring systems in nutritional researches. Since prison is an isolated place and prisoner’s state of health to some degree depends on the food consumed، therefore the nutritional status by this index might have some implementations for the policy makers. In a cross sectional study 435 prisoners (48 females and 387 males) were recruited using stratified random sampling method proportional to the ward population. Food intake from different sources in prison was assessed by analysing prison food menu، measuring wasted foods and food bought and provided by prison supermarkets. HEI score in Mashhad Central Prison was 80 percent of the total calculated score. Scores for consumption of fruit، meat and poultry، dairy products and food variety were 0، 4، 9. 5 and 9 respectively. Other food groups concerned with vegetable and cereals had scores of 10. Sodium intake representing the salt consumption was not measured. The results of this study showed that eating pattern of prisoners is healthy but steps might be taken to improve the quality of the food consumed.

Achillea is a plant widely used in traditional medicine for gastrointestinal disorders. The aim of this study was to investigate the preventive effect of Achillea wilhelmsii hydro-alcoholic extract on indomethacine-induced gastric ulcer in rats. It was an interventional study and done on six groups of male Wistar rats (n=8 in each group). Three doses of Achillea wilhelmsii extract (200, 400 and 800 mg/kg) were given orally to three groups for three days. After the third day the indomethacine in methyl cellulose (1%) suspension were given orally to the rats and the animals were anesthetized after 6 hours and the pylorus ligatated for one hour. Then the gastric juice extracted and gastric acid titrated by NaOH. The preventive ratio, gastric mucus secretion, NP-SH compounds and lipid peroxidation were measured. Achillea wilhelmsii extract clearly prevented indomethacine- induced ulcer. The Achillea wilhelmsii extract reduced gastric acid secretion by 400 and 800 mg/kg doses compare to the indomethacine group. The extract increased gastric mucus which was significant by 800 mg/kg dose. NP-SH compounds increased significantly by 200 and 800 mg/kg doses in comparison the indomethacine group. Lipid peroxidation noticeably reduced by all three doses. The Achillea wilhelmsii extract showed obviously preventive effect on indomethacine-induced gastric ulcer. Although the potency of the extract on inhibition of gastric acid secretion and increase of gastric mucus secretion are important in this preventive effect but antioxidant effect of the extract is more prominent.

This study was conducted to investigate motivational structure (MS) and eating behavior of the women, registered in one of the sports clubs in Mashhad city, North East of Iran. In this descriptive study, sixty overweight women (Mean of BMI=29.93 kg/m2, SD=3.71) and sixty normal weight women (Mean BMI=21.36 kg/m2, SD=1.79) completed the Personal Concern Inventory (PCI) and Dutch Eating Behavior Questionnaire (DEBQ). To test the hypotheses of the study, MANCOVA, ANOVA and Regression analysis were used. The results showed that, compared with controls, overweight and obese women had a more MS (P≥0.001), and on the DEBQ, they scored higher on emotional eating (P≥0.001) (including confused emotions (P≥0.001) and clearly labeled emotions (P≥0.001)) and external eating (P=0.001). Moreover, overweight and obese women who reported frequent failures with their diet had more maladaptive MS (P≥0.001) than overweight and obese who are successful in their diets. Furthermore, the results of hierarchical Regression analyses showed that motivational structure can predict the participant's BMI (P≥0.001) and the number of dieter's failures (P≥0.001), independent of the effects of age and education. Eating style could predict BMI (P≥0.001). Overweight and obese women had more maladaptive MS than women withnormal weight, and the two groups had a different eating behavior. Overweight and obese women who reported frequent failures with their diet had more maladaptive MS than those with successful dieting history. Moreover, motivational structure could predict the participant's BMI and the number of dieter's failures. Eating style could predict the BMI.

Surgical wound infection is the most serious complication after surgical treatment and the second most common etiology in nosocomial infection. Nutritional status of the patients is one of the risk factors for surgical site infection (SSI). This study aims at investigating the relationship between the serum albumin level and pre-operative anemia with surgical site infection in patients with open tibial fracture. In a prospective study 56 patients with open tibia fractures were studied in a teaching hospital in Mashhad-Iran. At the time of admission serum albumin level hemoglobin and anthropometric values were measured. Surgical site infection during a one-year follow-up was recorded. The results were analyzed using statistical tests. Nineteen patients (%33.9) were complicated by infection. The odd ration was 1.83 (p=.032) for anemia 2.35 (p=. 018) for hypoalbuminemia and 3.53 (p=.002) for type of open fracture. This study showed that SSI is a problem of great significance in orthopaedic tibia open fracture surgeries. It also showed that hypoalbuminemia and anemia before surgery resulted in a higher SSI occurrence in the patients.