جستجوی مقالات مرتبط با کلیدواژه « glutathione » در نشریات گروه « تربیت بدنی »

The purpose of this study was to measure the changes in oxidized (GSSG) and reduced (GSH) glutathione, glutathione reductase (GR) and glutathione peroxidase (GPX) after repeated-sprint activity (RSA) and subsequent cold water immersion (CWI). Twenty trained athletes with maximal oxygen uptake (VO2max) 52.9±2.9 ml.kg-1.min-1, age 21.9±2.2 yrs, height 174.2±5.4 cm, and weight 68±4.4 kg was assigned to take part in this study. After performing repeated-sprint activity, 10 participants immersed in cold water (14°c) and 10 participants passively sat on a chair at room temperature. Blood sampling was performed before and after RSA, after CWI or passive rest and after 24 h. The blood variables assessed through ELISA method. The results showed that antioxidant levels did not return to baseline levels and CWI had no effect on these factors, compared to GPX and GR returned to baseline levels after 24 h, nevertheless; there was no significant difference between CWI and Control groups. In conclusion, although the levels of enzymatic and non‐enzymatic antioxidants were significantly higher after RSA, CWI did not have any effect on returning to baseline levels after 24h.

The purpose of this study was to investigate the effect of eight weeks of aerobic training combined with propolis on lipid peroxidation in obese men.

This was a quasi-experimental study with three experimental groups and one control group with pre-test and post-test. Thirty-eight subjects were selected by simple random sampling. They were randomly divided into four groups of nine individuals: aerobic exercise, propolis supplement, aerobic exercise + propolis supplement and control group. After selecting the statistical sample, the subjects were randomly divided into four groups (aerobic exercise group, placebo group, aerobic exercise + supplementation group and control group). To achieve this goal, a demographic questionnaire and medical-athletic history questionnaire were used. Then height and weight were measured. After the main session day after the first blood sample was taken as a pretest, the first group participated in aerobic training for eight weeks. The placebo group and the placebo group received two 500 mg propolis and placebo tablets, respectively, twice daily.

The results showed that aerobic exercise combined with propolis reduced cholesterol, triglyceride and malondialdehyde in obese men but had no effect on glutathione.Keywords: Aerobic exercise, Propolis, Lipid profiles, Malondialdehyde, Glutathione

Intense exercise damages tissues and disturbs some cellular processes through oxidative stress and antioxidants can modulate intense exercise-induced oxidative stress. The aim of the current study is to examine the effect of short-term selenium on serum hydrogen peroxide (H2O2) and Glutathione (GSH) supplementation of inactive male university students, following a session of acute exhaustive aerobic training.

The present study is a semi-experimental study with a cross-sectional design, which was conducted at the laboratory of the University of Birjand in the year 1397. 10 inactive male university students at the average age of 18.60 ± 0.84 and BMI of 21.38 ± 3.61 ml/kg/min were randomly selected for this research. The 10-member group attended four stages, called control, training, supplementation, and training + supplementation group, in a cross-sectional way. The training protocol which has been used in the test was Bruce Protocol. After attending one training session, the subjects took selenium supplementation in the form of capsules (200 mg daily) for 14 days. Immediately after the training, the blood samples were taken from arm vessels and was analyzed. For the determination of the normal distribution of data, the Shapiro-Wilk test has been employed. Then an analysis of variance repeated measure test and dependent t-test were used for extraction of results at the significant level of p<0.05.

The results showed that following acute exhaustive aerobic training, H2O2 serum levels have increased significantly (p=0.01) and then significantly decreased (p=0.001) by taking selenium supplementation for 14 days (p=0.001); however, after training and selenium supplementation, GSH serum levels did not show any significant changes (p=0.27).

Since taking selenium supplementation for 14 days could significantly decrease the high H2O2 levels, following a session of acute exhaustive aerobic training, it seems that this supplementation can have a positive effect on the oxidative stress, caused by acute training.

The aim of this study was to evaluate two different intensity of resistance training with the same volume on the plasma levels of malonyl dialdehyde (MDA), reduced glutathione (GSH) and total antioxidant capacity (TAC) in healthy men. 30 healthy men with aged 20-25 years participated in this study and were randomly divided into three groups of moderate-intensity resistance training (hypertrophy), high intensity resistance training (strength) and the control group. Hypertrophy resistance training (3 sets of 10 repetitions with 70% of one repetition maximum) and strength training (4 sets of 6 reps with 85% of one repetition maximum) for 8 weeks and were administered three times a week. Venous blood samples were obtained from the subjects during fasting and two times, 24 hours before the start of the protocol and 48 hours after the last training session. Repeated measure ANOVA revealed that MDA concentration was significantly reduced in exercise groups compared to control group. In addition, the amount of the reduction in hypertrophy training was more compared with strength training group (P=0.0.4). GSH concentration was significantly increased in exercise groups compared to control group. Hypertrophy training was more increases in GSH levels compared with strength training. TAC levels increased in both groups, but the increase was significantly only in hypertrophy training but was not found a significant difference between the groups. In conclusion may be resistance training could improve antioxidant system (GSH and TAC) and decrease the MDA and it was independent from intensity of training.