جستجوی مقالات مرتبط با کلیدواژه « total antioxidant capacity » در نشریات گروه « تربیت بدنی »

Performing sports activities along with the consumption of herbal supplements, especially in people, have different effects on the body's antioxidant and oxidant systems. The purpose of this research was to investigate the effect of eight weeks of intense interval training with chlorella supplementation on serum levels of malondialdehyde and total antioxidant capacity in obese or overweight middle-aged women. The statistical population of the present study consisted of overweight or obese middle-aged women (BMI ≤ 25) with an age range of 40 to 65 years. A number of 40 subjects were selected by invitation and based on the study entry criteria and randomly divided into four groups: exercise and supplement (10 people), exercise and placebo (10 people), supplement (10 people) and control (10 people). became HIIT exercises consisted of periods of 60 seconds of maximum intensity running (85-95% of the reserve heart rate) followed by 60 seconds of low-intensity running (55-60% of the reserve heart rate). The subjects did 6 times in the first week, 8 times in the second week. they completed the third to fifth weeks 10 times and the sixth to eighth weeks with 12 repetitions. Shapiro-Wilk test for normality of data and correlated t-test, one-way analysis of variance and Tukey's post hoc test to test hypotheses was used and the significant level was considered at the alpha level of 5%.

Increased free radicals and oxidative stress are among the factors that can accelerate the aging process. The aim of this study was to investigate the effect of eight weeks of high-intensity interval training (HIIT) on oxidant and antioxidant capacity and motor performance indices in the elderly people.

The participants of this study were 24 elderly people (age=71.88±5.06 year) from Bandar Abbas city. Subjects were randomly divided into two groups including control (n=12) and HIIT (n=12). Then, the subjects in the training group performed training protocol, three days a week for eight weeks. During each session, the subjects performed four three-minute workouts with an intensity of 85 to 95% maximal heart rate with three active sets of three-minute rest with 65 to 75 maximal heart rate. Twenty four hours before and 48 hours after last session of HIIT, the variables were measured via standard tests. The analysis of covariance test was used to analyze the data at significant level of p≤0.05.  

Eight weeks of HIIT significantly reduced the total oxidant status, but the total antioxidant capacity and serum levels of sestrin-2 showed significant increase (p<0.001) in the elderly people. Moreover, eight weeks of HIIT improved the gait speed (p<0.001), timed-up-and-go (p<0.05), and maximal oxygen uptake (p<0.001). However, these training protocol could not have a significant effect on time of chair stand test (p=0.22).

HIIT can be use as a useful exercise training method in the elderly people with attention of  training considerations.

Introduction and  Oxidative stress and subsequent oxidative damage is one of the main factors in the development of non-alcoholic fatty liver disease (NAFLD). The aim of present study was to investigate comparison the effect of High Intensity Interval Training (HIIT) with and without Portulaca Oleracea Extract on Serum Level of Malondialdehyde (MDA) and Total Antioxidant Capacity (TAC) in Rats with (NAFLD). Twenty five male Wistar rats were randomly divided into five groups: healthy control, fatty liver control, Portulaca Oleracea, HIIT and HIIT+ Portulaca Oleracea. To induce NAFLD, the rats were fed a high-fat diet for 12 weeks. Portulaca Oleracea supplement at 400 mg/kg was given to the experimental groups. HIIT was performed for 8 weeks, 5 sessions per week with 7 repetitions of 1 minute at 90% maximum speed accompanied by active rest intervals including 2 minutes of running at 20% mmaximum speed. To analyze the data, one-way analysis of variance and Tukey's post hoc test were used at the significance level of p<0.05. Serum Level of MDA in fatty liver control was higher than healthy control group (P=0.034). Level of this index in Portulaca Oleracea Extract and HIIT+ Portulaca Oleracea groups were significantly lower than fatty liver control group (P values 0.021 and 0.049 respectively). But No significant difference was observed in the serum level of MDA in the HIIT group compared to the fatty liver control group (P=0.08). Serum level of TAC were significantly higher in Portulaca Oleracea Extract than healthy control and fatty liver control groups (P values 0.044 and 0.001 respectively). Level of this index in HIIT+ Portulaca Oleracea Extract group was significantly higher than fatty liver control group (P=0.003).Discussion and It seems that long term HIIT and Consumption of Portulaca Oleracea extract by reducing lipid peroxidation and improving antioxidant factors in NAFLD subjects, can play an important role in controlling the progress of this disease.

Alzheimer's disease is a neurodegenerative disease that gradually destroys memory and cognitive skills. The present study was conducted to investigate the effect of twelve weeks of endurance training along with hawthorn consumption on some oxidative stress indicators in the serum of Alzheimer's male rats. In this experimental research, 30 male Wistar rats were randomly divided into 5 groups. Healthy control, Alzheimer's control, Alzheimer's and endurance training, Alzheimer's and endurance training with hawthorn consumption, and Alzheimer's with hawthorn consumption were divided. Endurance training groups (swimming) trained for 12 weeks, 5 days a week and each session started for 15 minutes and up to two sessions of 60 minutes a day. The supplement receiving group received the mixture of hawthorn powder with the standard food of mice at a ratio of 6.25% of hawthorn powder. 24 hours after the last training intervention, the rats were unconscious and the serum levels of SOD, GPX, TAC and MAD were determined by Eliezer method. In order to estimate the desired indicators (superoxide dismutase enzyme, glutathione peroxidase enzyme, total antioxidant capacity and malondialdehyde), blood sampling was done from the inferior vein of rats. The SPSS 22 software and one-way ANOVA test followed by Tukey's post hoc test with a significant level of p≤0.05 were used to analyze the data. The results showed that endurance training, especially at the same time as hawthorn consumption, led to a significant increase in serum levels of glutathione peroxidase compared to other groups (P = 0.002). However, there was no significant change in the serum level of superoxide dismutase (P = 0.129), total antioxidant capacity (P = 0.156) and malondialdehyde (P = 0.498) in the control and experimental groups. Considering that the first line of defense against oxygen toxicity is superoxide dismutase, and to complete the process of eliminating hydrogen peroxide, the enzymes catalase and glutathione peroxidase must be helped. As a result, it can be said that in this study, superoxide dismutase, like glutathione peroxidase, was increased, but no significant difference was observed between the groups in the statistical results.Using hawthorn extract and performing endurance exercises during the week, at moderate intensity and in a regular and intermittent manner, can lead to a reduction in oxidative stress due to an increase in serum levels of total antioxidant capacity and first and second line defense enzymes (superoxide dismutase and glutathione). peroxidase and decrease the serum level of malondialdehyde in Alzheimer's experimental model, based on the results of this study and reviewed previous studies, these models can be suggested as side treatment in Alzheimer's patients, especially in the early stages.

One of the appropriate strategies for combating the adverse effects of oxidative stress caused by strenuous activities is consuming a well-balanced diet and taking antioxidant supplements. The purpose of this study was to investigate the effect of jujube extract consumption during two types of intermittent and intense endurance training on antioxidant indices and oxidative stress of the liver tissue of immature male rats.

72 male Wistar rats (aged= 22 days, weight= 60.64 ± 7.475 g) were randomly divided into nine groups after being weighed: control, placebo, jujube, intense endurance training (ICT), ICT + placebo, ICT + jujube gavage, high-intensity interval training (HIT), HIT + placebo gavage, HIT + jujube gavage. After a week of general and specific familiarization, the ICT protocol including running on the treadmill for four weeks (five sessions per week) with progressive duration and intensity and following the principle of exercise overload was implemented on an animal treadmill. So that the speed in the first week was equal to 10-18 meters per minute and its duration was 10-30 minutes, and in the last week the training speed reached 30 meters per minute and its duration was 55-60 minutes. The HIT training protocol was also carried out in the form of training with the pattern of seven-day courses (six days of training and one day of rest to prevent overtraining). Based on the principle of overload, training was applied in such a way that the training speed in the familiarization week was equal to 10-16 meters per minute and its duration was one minute, and in the last week the training speed reached 36-40 meters per minute (equivalent to about 85% of Vo2max). Distilled water was given to the placebo groups, and 600 mg/kg of jujube extract was given daily to the jujube groups after training. The activity of GPX, SOD, CAT enzymes, TAC and MDA was assayed by spectrophotometric method using diagnostic ELISA kit. ANOVA and Tukey's post hoc test were used to analyze the data.

The results showed that ICT and HIT significantly decreased MDA activity (P < 0.05). However, ICT and HIT did not affect the activity levels of antioxidant enzymes (SOD, GPX) and TAC (P > 0.05). On the other hand, HIT training significantly increased CAT enzyme (P < 0.05). The results also showed that groups with jujube gavage did not have a significant effect on the activity levels of antioxidant enzymes (SOD, GPX, CAT), TAC and MDA (P > 0.05).

it seems that ICT, HIT moderates oxidative indices, and HIT training improves the antioxidant index CAT in immature rats.

Melatonin is the hormone with different physiological effects, especially on analgesic and anti-inflammatory properties. contradictory reports published on the effect of melatonin on exercise performance. The present study attempt aimed to determine the effect of one-week oral administration of melatonin on delayed-onset muscle soreness (DOSM).  In this semi-experimental study, 24 healthy male subjects randomly divided into experimental and control groups. The experimental group received 6 mg per day melatonin, seven days before eccentric exercise and control group similarly received placebo. Muscle soreness produced in both feet during descending from a 50 cm bench. Serum Lactate dehydrogenase (LDH) and Creatine phosphokinase (CPK) concentration and total Antioxidant capacity (TAC) as well as the Visual Analogue Scale (VAS) of the pain and pressure pain, 7 days before eccentric protocol and 24, 48 and 72 hours after that were measured. Repeated measure analysis of variance (ANOVA) with Bonferroni comparison between two groups in each time was employed at p CPK concentration was significantly increased in the placebo group when compared before and 24 hours after DOMS (P<0.001). Perceived pain and pressure pain, 7 days before protocol and 24 and 48 hours after protocol were significantly higher in the experimental group (P<0.01). The results of this study indicated no significant increase in the TAC and the same oral supplementation with melatonin consumption (6 mg per day for seven days) had no positive effect on TAC and the biochemical and clinical symptoms of the DOMS, therefore it seems melatonin increases pain in the DOMS.

The aim of this research was to study the effect of different doses of licorice root with resistance training on blood glutathione peroxidase activity and total antioxidant capacity in sedentary and overweight men. In a semi-experimental trial with double-blind, 90 sedentary and overweight men were divided in six groups of fifteen people: (G1: NRT+SG250mg in the day, G2: NRT+SG500mg in the day, G3: SG250mg in the day, G4: SG500mg in the day, G5: NRT+P250mg in the day and G6: C+P250mg in the day). The resistance training program was conducted for 8 weeks and three sessions per week. Within-group results indicate a significant increase in glutathione peroxidase and total antioxidant capacity in the NRT+SG250mg (P=0.023), NRT+SG500mg (P=0.014) and NRT+P250mg (0.038) group. The highest percentage significant incremental changes of glutathione peroxidase (4.10%) and total antioxidant capacity (29.71%) was related to NRT+SG250mg group. Between-group results showed that there was incremental significant difference between the NRT+SG250mg, NRT+SG500mg, and NRT+P250mg with SG500mg, SG250mg and control groups in the mean concentration of glutathione peroxidase and total antioxidant capacity (P<0.05). Probably, performing resistance training along with taking licorice supplementation can be effective in enhancing the antioxidant status of sedentary and overweight men.

Increased production of free radicals during metabolism and physical activity are significant biological changes that oxidative stress in the body can provide background incidence of many diseases. The purpose of this study was to evaluate the effect of 2 week aerobic exercise with royal jelly supplements on Male vistar Rats. in this study 20 male vistar rats were divided randomly into practice with complementary and non-complementary exercises. Training Program includes 30 minutes of running on a treadmill to exhaustion at a speed of 12 meters per minute and 5 days a week and 300 mg per kg of body weight of royal jelly daily orally supplemented for 2 weeks. the data were analyzed using the Kolmogorov-Smirnov and T-test. The significance level in this study was considered to be 0.05. The superoxide dismutase and total antioxidant capacity was increased significantly after two week aerobic exercise with royal jelly supplements. This study showed that eating royal jelly reduces oxidative stress.

Background and Severe and long physical activity especially in a hot and humid environment produces reactiveoxygenspecies. The aim of this study was to determine the use of two weeks coenzyme Q10 (CoQ10) supplementation and pre-cooling strategy on serum oxidative stress (MDA), total antioxidant capacity (TAC) and body core temperature (Tc) indices during recording in elite swimmers.
Thirty-two healthy male were randomly divided into four equal groups including supplementation, supplementation with pre-cooling, pre-cooling and placebo. All subjects were participated in 18 session’s protocol with speed and endurance swim workouts, a distance of 5 Km per session. Sampling were immediately obtained before first recording and before and after second recording. ANCOVA and Repeated measurement tests and Paired T-Testwere used for data statistical analysis (α= 0.05).
The results showed that there was no significant statistical difference between MDA, TAC and Tc indices in the first stage among four groups (P>0.05). But there was a significant statistical difference for indices in the second and third stages (P˂0.05).
CoQ10 supplementation increases serum total antioxidant capacity and adverse changes swimmer’s malondialdehyde and Tc during drills and recording. Meanwhile, these results were no observed for the precooling but could reduce Tc.

The aim of this study was to evaluate two different intensity of resistance training with the same volume on the plasma levels of malonyl dialdehyde (MDA), reduced glutathione (GSH) and total antioxidant capacity (TAC) in healthy men. 30 healthy men with aged 20-25 years participated in this study and were randomly divided into three groups of moderate-intensity resistance training (hypertrophy), high intensity resistance training (strength) and the control group. Hypertrophy resistance training (3 sets of 10 repetitions with 70% of one repetition maximum) and strength training (4 sets of 6 reps with 85% of one repetition maximum) for 8 weeks and were administered three times a week. Venous blood samples were obtained from the subjects during fasting and two times, 24 hours before the start of the protocol and 48 hours after the last training session. Repeated measure ANOVA revealed that MDA concentration was significantly reduced in exercise groups compared to control group. In addition, the amount of the reduction in hypertrophy training was more compared with strength training group (P=0.0.4). GSH concentration was significantly increased in exercise groups compared to control group. Hypertrophy training was more increases in GSH levels compared with strength training. TAC levels increased in both groups, but the increase was significantly only in hypertrophy training but was not found a significant difference between the groups. In conclusion may be resistance training could improve antioxidant system (GSH and TAC) and decrease the MDA and it was independent from intensity of training.

Oxygen reactive species are produced in response to exhausting exercise, which results in lipid peroxidation and cellular damage. The use of antioxidant supplements reduces the oxidative stress caused by such exercises. The purpose of this study was to investigate the effect of zinc and copper supplements on total antioxidant capacity and malondialdehyde after passive exercise activity in girls. In this quasi-experimental study, 24 non-active students qualified in the technical university of Tabriz were voluntarily participated and randomly divided into 3 separate and synergistic groups of zinc and copper, half an hour before and immediately after Bruce Blood Test was used for blood sampling and after a one-week follow-up, the participants participated in the test and re-blood sampling. Data were analyzed using SPSS16 software, t-test and one way ANOVA The increase in level of malondialdehyde in the exogenous exercise group was significantly lower in the zinc group. Total antioxidant capacity of zinc group increased significantly after exercise (but in other groups there were no significant changes. The results showed that free radicals are effective in lipid peroxidation, and antioxidant supplementation of zinc has a significant role in reducing this injury. Key words: Zinc and Copper Supplement, Total antioxidant capacity, Malondialdehyde, Exodus Exercis

Exercise increases the production of free radicals, which may damage a number of cell constituents. Organisms have developed a sophisticated antioxidant system for protection against free radicals. This study was carried out to compare the antioxidant and oxidative stress status and lipoprotein profile of sprint runners and non-athlete. Total antioxidant capacity (TAC), malondialdehyde (MDA), conjugated dienes (CD) and Serum lipid and lipoprotein profile (triglycerides, total cholesterol, HDL-cholesterol, LDL-cholesterol and VLDL-cholesterol) were measured in 14 male sprint runners and in equal number of age-matched non-athletes. It was found that the plasma values of MDA, CD and TAC were similar in both. groups. Athletes showed lower plasma level of total cholesterol (p=0.02). Also runners had lower levels of LDL-cholesterol, triglycerides, VLDL-cholesterol and LDL/HDL ratio but they were not significant. The result suggests that regular anaerobic training dose not lead to. oxidative stress in sprint runners and also it does not have a significant effect on improvement of their lipoprotein profile.

Background and The use of antioxidant supplements is vital for reduction of damaging effects of free radicals after acute exercises. Therefore, the present study aimed to examine the impact of jujube fruit consumption on total antioxidant capacity (TAC) and malondialdehyde (MDA) in young women after a single bout of the intense resistance exercise. Eighteen young non-athletes female were randomly divided into two equal groups including jujube fruit consumption+intensive resistance exercise and intensive resistance exercise groups. The first group received jujube daily 0/4 g/kg of body weight for 3 weeks. Both groups carried out a session of intensive resistance exercise consisted of 5 movements at 90% of one repetition maximum (1RM). Blood samples were measured in three phases included baseline, after 3 weeks of the jujube consumption, and after the resistance exercise session. TAC and MDA were measured using Ferric reducing antioxidant power (FRAP) assay and thiobarbituric acid (TBARS), respectively. For extraction of results the repeated measures ANOVA and LSD tests were applied at a significance level of p≤ 0/05. In intensive resistance group, TAC significantly decreased (p<0/02), but in the jujube+intense resistance group it is observed a significant increases in the TAC (p<0/03) after a 3-weeks of jujube consumption, which had accompanied with absence of significant changes (p<0/11) in this parameter immediately after exercise session. On the other hand, the MDA did not change significantly (p>0/05) in both groups in different phases on study which indicator of non-influencing of jujube consumption and intensive resistance session on this parameter. Jujube fruit consumption before performing of intensive resistance training can be a suitable stimulus for strengthen of antioxidant system and control of damaging effects of free radicals following resistance exercises.

This study was conducted to identify the effect of acute caffeine intake and one-session resistance exercise on total antioxidant capacity (TAC) and serum malondiadehyde (MDA) in male volleyball players. Twenty male volleyball players (age 21.20±1.24 years, body fat 10.75±2.78 %, and BMI 22.95±0.99 kg.m2) in a randomized design in two equal groups: supplement and placebo (6 mg.kg-1 caffeine and dextrose) were allocated. After the supplementation all subjects were participated in resistance weight- exercise protocol (7 stations in 3 sets per station with 80% of 1-RM until exhausted). Changes in serum of TAC and MDA were determined in three phases (before and 45 min after the supplementation and immediately after the exercise protocol).The normal data were expressed as Mean (±SD) and analyzed by repeated measure ANOVA, bonferroni and independent T test at α≤0.05. The results show that the acute caffeine intake had no significant effect on the basal serum TAC and MDA (P≥0.05). Whereas, one-session resistance exhaustive exercise significantly reduced TAC (P≤0.05) and significantly increased in the MDA (P≤0.05). However, no significant differences in any of the measured variables between the groups were found immediately after resistance exercise (P≥0.05). The present results show that acute caffeine consumption probable had no significant increased basal TAC and also can not decrease the undesirable alterations of serum MDA induced one-session of resistance exercise in male volleyball players.

HSP72 and TAC are two factors from internal defense of body. The purposeof this study was to investigate the effects of acute treadmill exercise on HSP72 in the plasmaof diabetic rats. Forty male rats weight 165±1 were assigned randomlyinto 4 groups: diabetic control group, and 3 diabetic+acute training groups, (included groups 1and2, and 3 that were killed 30 minute, 4 hours and 24 hours postexercise respectively). Diabetes wasinduced with injecting streptozotocin (dissolved in 0.1 M citrate buffer, pH 4.5) into the abdominalcavity. Rats were subjected to treadmill exercise, and the speed of the treadmill was 10 m/min,and then gradually increased until 18 m/min (grade 0%). The duration of the treadmill exercise was60 minutes. For determination of HSP72 and TAC values, respectively sandwich Elisa and decolorizationwere used. Acute exercise training increased the plasma HSP72 in the groups2 and 3, but in group 1 no significant changes took place. HSP72 levels significantly increasedin the group 2 (P=0.03) and 3 in compared with groups 1 and 2 (P=0.001 and P=0.005 respectively).Increase in TAC levels only in group 3 compared to control group was significant (P=0.03). These results show that acute treadmill exercise improved HSP72 levels and TACin diabetic’s subjects and have benefit effects. Therefore probably acute exercise treadmill couldrecommend as a therapeutic strategy for diabetes.

It is believed that the amount of antioxidant enzymes activity increases during the moderate aerobic exercise and protects the tissue against the oxidative stress. The aim of the current study is to compare the endurance swimmers with non-athletes males regarding three factors: Total Antioxidant Capacity (TAC), Glutathione Peroxides (GPX), and serum lipid profile. For the purpose of the study, 25 endurance swimmers participated in swimming exercises for three 45 minutes sessions every week seven months before the study. The 23 non-athletes selected did not participate in any regular physical exercises in the same period. TAC was measured according to FRAP method, GPX was measured by controlling the reaction of Autoxidation Pyrogallol, and Profile Lipid indexes density was measured according to Pars company’s Enzymatic standard kit methods. The result showed that the amount of TAC, GPX, and maximal oxygen uptake(VO2max) of the swimmers was significantly higher than the non-athletes(P < 0.05), but their BMI and fat body percent were significantly lower than the nonathletes(P < 0.05). Moreover, it was observed there is not any significant difference between Uric Acid, Bilirobin, and Lipid indexes of the two groups (P > 0.05). Therefore, performing special swimming exercises regularly result in improvement and fortification of antioxidant system against the oxidative stress produced during exercise.