جستجوی مقالات مرتبط با کلیدواژه "کاراگینان" در نشریات گروه "شیلات"

Carrageenan is a marine biopolymer that can be extracted from cell wall of some red carrageenophyte. In this present, response surface methodology was used to investigate the procedure of carrageenan melting point and gelling temperature from algae of Hypnea flagelliformis. Independent variables, alkalinity concentration (0/25-2%), extraction temperature (70-90°C) and extraction time (60-240 minutes) were applied in five levels. all Base on the result, effects of all independent variables on melting point were significant (p<0.05), whereas alkalinity concentration had significant effect on gelling temperature (p>0.05). Polynomial models developed for the melting point and gelling temperature indicated that optimum conditions. Optimum data for independent variables were alkalinity concentration 1.54%, temperature 85 °C and time 203 minutes.Confirmatory test was earned as follows melting point 63.8 ±0.91 °C and gelling temperature 37.29 ±0 /62 °C. The experimental data and model forecasting were similar (P> 0.05).

Sea cucumber is one of the most important species of Echinodermata, belongs to the category of Holothuroidea. Their well-known bioactive compounds have anti-cancer, anticoagulant, antihypertensive, anti-inflammatory, antimicrobial, antioxidant, anti-arterial, and wound-healing effects. In this study, the anti-inflammatory effect of methanolic extract on the muscular body wall of sea cucumbers Holothuria leucospilota on Albino rats was investigated. Sea cucumbers were collectted from the Hengam island, dried and extracted with hexane, ethyl acetate and methanol. The extracts were evaluated by lipoxygenase enzymes inhibition test in in vitro conditions. In in vivo experiments, the animals were divided into 5 groups of 6 rats, including: control, treated with carrageenan, treated with MEHL extract (100/200 mg / kg) and aspirin 10 mg/kg. In order to evaluate the inflammation, carrageenan test was used in Hind paw edema method. In in vitro experiments, methanolic extract (MEHL) with 43.75± 2.83 and ethyl acetate and hexane extract showed 12.92 ± 1.22 and 9.74 1.57 percent inhibition of lipoxygenase enzymes, respectively. Methanolic extract (MEHL) Holothuria leucospilota was selected for further in vivo testing. In animal experiments, MEHL, with concentrations of 100 and 200 mg/kg, inhibited hind paw edema at 3 and 4 hours, with 13.62 ± 1.3 and 35.15 ± 2.5 and , 18.41 ± 1.7 and 45.22 ± 3.2 percent, respectively. Holothuria leucospilota methanolic extract contains anti-inflammatory compounds that have shown better anti-inflammatory effects compared to the anti-inflammatory drug acetylsalicylic acid.