جستجوی مقالات مرتبط با کلیدواژه "burn" در نشریات گروه "پزشکی"

Burns are the leading cause of disability and mortality in the world, which has led to serious economic and social consequences. 
The present study aimed to investigate fungal infections in burn patients admitted to Ali-ebn Abitalib Hospital in Zahedan.
This study was conducted from April 2023 to October 2023. The research population was 113 burn patients admitted to Ali-ebn Abitalib Hospital. Data was collected by recording demographic data, sampling lesions suspected of fungal infection, and laboratory tests. All samples were recognized using phenotypic methods such as microscopy and culture on Sabouraud dextrose agar with chloramphenicol. The data was analyzed using SPSS software version 26.
About 13.3% of the studied burn patients had a positive fungal culture. The most common fungus grown in burn patients was Candida albicans/C. dubliniensis (46.6%), Aspergillus niger species complex (40%), Fusarium spp. (13.3%) Furthermore, Aspergillus fumigatus species complex (13.3%) and the prevalence of other species was less than 10%. It was also found that positive fungal culture in burn patients is directly related to age, high percentage of burns, and length of hospitalization. 
Considering the high prevalence of fungal infection in burn patients and the identification of influential risk factors, all patients should be examined for fungal infection.

The current COVID-19 pandemic has changed human lifestyle to follow COVID-19 Appropriate Behaviours (CAB) and that includes social distancing, and the use of masks and sanitiser for hand hygiene. With increased use of sanitiser; the incidence of burns due to sanitiser has been reportedly on the rise. The study analysed the reported burn incidences due to sanitiser, found the relation between sanitiser and the aetiology of burn and formulated guidelines for its safe use. The authors also suggested Do’s and Don’ts to prevent and manage sanitiser burns.

An online search was made to search the articles related to sanitiser burn targeting the words ‘sanitiser’, ‘hand sanitiser’, and ‘burns and burns injury’. A general Google search was also made to look for any news reported in electronic media for sanitiser burns.

A total number of 10 scholarly articles mentioning 95 cases were found satisfactory to fulfil the inclusion criteria. Most of the cases were flame burns due to the ignition of alcohol-based sanitiser (n=92, 98%) either by mistake or while lighting the flame for cooking or cigarette for smoking. In all cases, it was found that alcohol-based sanitiser was the agent causing burns which were more due to gel form. 61 patients were managed on an outpatient basis whereas 33 patients required admission.

Increasing use of sanitisers can be related to increased incidence of burns. Its safe use is warranted with proper guidelines.

Burn injury is still the leading cause of mortality and morbidity in burn patients.  We comapred healing effect of Hypericum perforatum, silver sulfadiazine and alpha ointments on burn injuries in rat model.

Sixty female Sprague-Dawley rats in an animal experimental study were randomly divided to 5 equal groups as H. perforatum, silver sulfadiazine and (SSD), alpha, gel base and the burn injury left untreated. Wounds were assessed macroscopically and histologic after burn injury and on days 7th, 14th and 21st after treatments.

Burn wounds decreased in size on day 7th in H. perforatum group (P<0.01). Regarding scoring the inflammation, re-epithelialization, angiogenesis, formation of granulation tissue and number of macrophage, the best scores were visible in H. perforatum group, and the worst in the gel base and the burn injury left untreated (P<0.01).

H. perforatum was shown to significantly induce re-epithelialization, angiogenesis and granulation tissue and decrease the inflammation resulting into a healing process in burn wounds. As H. perforatum is inexpensive and an easily available herbal medicine, it can be considered as a therapeutic of choice to ameliorate burn injuries.

This research aimed to examine the frequency of resistance to antimicrobial agents and their variations in Pseudomonas aeruginosa clinical isolates, which are accountable for invasive infections in the southern part of Iran, from 2018 to 2022.

A retrospective study was conducted, involving the gathering of microbiological data from Taleghani Burn Hospital from 2018 to 2022. The primary variables under scrutiny were department, sample origin, the antiprogram system (e.g., disc diffusion and strip methods, and clinical laboratory standards), and the rate or percentage of resistant isolates investigated by antimicrobial susceptibility testing. The interpretation criteria employed for the study were those of the Clinical Laboratory Standards Institute (CLSI). And the percentage of resistant isolates was also taken into consideration.

The disc diffusion and strip method is the most commonly used approach for antimicrobial susceptibility testing. According to the CLSI, resistance rates ranged from 3.64% (colistin) to 77.38% (amikacin). The rates of antimicrobial resistance remained relatively constant over time in 2018-2022. Approximately 67.62% of isolates were multidrug resistant, and the remaining 9.46% were extensively drug-resistant. Wound and urine isolates demonstrated higher resistance, except for amikacin and piperacillin, than those from blood culture and biopsy.

Antimicrobial resistance is widely prevalent in P. aeruginosa, a common bacterium in southern Iran. The findings revealed the highest resistance rates for commonly used antibiotics such as amikacin, piperacillin, ceftazidime, and meropenem. However, colistin and nitrofurantoin are more effective against this bacterium. The wound and urine isolates represented the highest resistance rates, indicating the need for prompt and appropriate treatment. Interestingly, the resistance rates for most antibiotics remained relatively stable during the study period, emphasizing the need to develop alternative treatments for P. aeruginosa infections.

Burn injuries are among the most significant causes of disability and death, having severe economic and social consequences in human societies.

This study aims to examine the effect of an exercise program on the quality of life of burn patients admitted to the burn department of Ali Ibne Abi Talib Hospital in Zahedan.

In this quasi-experimental study, 30 patients with shoulder joint burns admitted to the burn department of Ali Ibne Abi Talib Hospital in Zahedan in 2021 participated. Patients meeting the inclusion criteria were selected via convenience sampling and then randomly assigned to intervention and control groups using permuted blocks. The intervention consisted of 4 individual training sessions and an exercise program. Patients in the intervention group performed exercises 3 times daily for 12 weeks, while those in the control group received only routine ward care. Data were collected using the Burn Specific Health Scale (BSHS), administered to groups 1- and 3-months post-intervention. Data analysis was conducted using SPSSv.21 software, employing the chi-square test, independent samples t -test, and repeated measures analysis of variance (ANOVA), with a significance level set at P < 0.05.

One month post-intervention, the mean quality of life scores were 121.73 ± 7.52 in the intervention group and 122.93 ± 5.72 in the control group. After 3 months, these scores changed to 156.46 ± 9.53 in the intervention group and 122.82 ± 8.09 in the control group, indicating a significant increase in the intervention group (P = 0.001). Repeated measures ANOVA revealed no significant difference in quality of life between the 2 groups 1 month post-intervention (P = 0.37); however, a significant difference was observed at 3 months (P = 0.001).

The study's findings suggest that exercise can improve the quality of life in patients with shoulder joint burns. Therefore, incorporating exercise and follow-up programs into the discharge plans of burn patients is recommended.

 Burns are wounds caused by thermal, chemical, electrical, or radiation injuries. They are complex wounds that are difficult to heal and are associated with thousands of deaths each year. Cinnamic acid (CA) is a natural organic compound found in plants, fruits, vegetables, and honey. CA possesses antimicrobial, anti-inflammatory, antioxidant, and wound healing properties.

 The aim of this study was to compare the healing effects of CA with silver sulfadiazine (SSD), a standard topical agent for burn treatment, on deep second-degree burns.

 This experimental study compared the healing effects of CA and SSD on second-degree burns. Fifteen New Zealand white rabbits weighing 2 to 2.3 kg were divided into 5 equal groups. Deep second-degree burn wounds were created on the backs of the rabbits by contacting a heated circular metal plate. The first group was treated with SSD 1% cream, the second, third, and fourth groups were treated with prepared ointments containing 0.1%, 0.5%, and 1% w/w of CA in Eucerin, respectively. The fifth group was treated with Eucerin alone. Wound healing effects were assessed by measuring the rate of wound contraction and the amount of collagen in tissue specimens obtained from different groups. Additionally, histopathological studies were performed on tissue samples.

 The results showed that CA was significantly more effective than SSD in burn wound healing. Cinnamic acid ointments significantly increased the rate of wound contraction (P < 0.05) and tissue collagen content (P < 0.001) compared to SSD and Eucerin.

 Our findings suggest that topical CA possesses burn wound healing properties and could be used as an effective topical agent for the treatment of burns.

Nowadays, herbal medicine with antimicrobial and anti-inflammatory activities, such as Arnebia euchroma, has been considered in the treatment of burn wounds. Therefore, this study aimed to determine the healing effect of Arnebia euchroma L on burn wounds in rats by reviewing the results of published studies in this field.

The keywords "Arnebia euchroma", "burn", and "rat", and their synonyms were explored in PubMed, Scopus, and ScienceDirect for English articles, and SID, Magiran, and Irandoc for Persian articles without time limitation until May 4, 2021. Inclusion criteria for this study were laboratory research articles focused on the effect of Arnebia euchroma L on wound healing in rats. Finally, the included studies were reviewed and assessed according to the given criteria.

Amongst the seven articles included in this research, four articles studied the healing effect of the medicine on second-degree burn wounds, one article addressed third-degree burn wounds, and two articles generally studied burn wounds. Arnebia euchroma L has been found to be effective in healing burn wounds in approximately 57% of studies, while the rest of the studies have emphasized its ineffectiveness in accelerating burn wound healing.  

The literature review demonstrated that Arnebia euchroma is effective in both healing and accelerating the recovery of burn wounds. Since there is an insignificant difference between the number of studies that have found this medicine effective and the number of those that have found it ineffective, further studies are required to determine the effectiveness of this medicine.

Providing timely and high-quality health services for pediatric burn cases is vital in reducing the death probability. The aim of this study was to demonstrate the value of P-Baux and R-Baux indexes in anticipating burn-related consequences among children.

The present cross-sectional investigation was carried out in 2018 at a burn referral center located in Tabriz. Through the census method, all children <12 years old who were admitted to the hospital with burn symptoms during the sampling period were included in the study. Data collection was carried out through a researcher-developed questionnaire. R-Baux and P-Baux scores were computed based on the patient's records. Data were analyzed using SPSS17 through multivariate logistic regression with a significance level of 0.05.

A total of 213 children were included in the study. In terms of mortality, the area under curve (AUC) of the R-Baux and P-Baux scores was similar (0.959). Moreover, the AUC of the outcomes for intensive care unit (ICU) admission and need for intubation was 99%. Logistic regression revealed a significant correlation between the need for intubation and death with both P-Baux and R-Baux scores (p<0.05). Admission to the ICU was only significantly related to the P-Baux score (p=0.022).

Utilizing P-Baux and R-Baux scores not only anticipates the death rate but also allows health service providers to prioritize patients and prepare proper facilities to prevent pediatric burn-related mortalities.

This study investigated the demographic characteristics and factors influencing burn injuries,primarily in low socioeconomic societies where such incidents are prevalent due to factors such as illiteracyand poverty. This cross-sectional study included all burn patients admitted to Shahid Motahari Hospital inTehran, Iran. Demographic data such as age, sex, occupation, education level, and residence as well as detailedinformation about the burn incidents such as date, time, location, number of people present at the scene, andreferral place was collected. Additionally, comprehensive burn details such as cause, extent, severity, previoushistory, and need for hospitalization directly at the emergency department were documented. The study included 2213 patients (mean age 34.98±19.41 years; range 1-96), with a men predominance(60.6%). The majority of burns (64.4%) occurred at home, primarily due to accidents (99.6%), with boilingwater being the most common cause (39.2%). The most frequent burns were second-degree burns (91.8%),with an average injured body area of 6.31±6.67%. There were significant correlations between burn severityand demographic factors such as age, sex, occupation, cause of burn, hospital admission, outcome, and lengthof stay. Remarkably, the extent of burns was negatively correlated with the distance to the hospital, whilepositively correlated with the length of hospital stay. Burn injuries were significantly influenced by demographic factors. Enhancing treatment facilitiesand reducing the time and distance to medical care could be crucial in high-risk cases.

 According to recent statistics, the rate of burns in Iran is higher than the world’s average. Therefore, it is necessary to improve the treatment protocols as much as possible.

 This study investigated the level of mineral intake (iron, zinc, selenium) and thyroid hormones (TSH, T3, T4) serum levels among burn patients.

 This cross-sectional study was conducted on 24 patients admitted to the intensive care unit (ICU) of Taleghani Hospital, Ahvaz, Iran. The Kolmogorov-Smirnov test was used to check the normality of the distribution of quantitative variables. Blood samples were taken on the first, third, and fifth days of hospitalization. Serum levels of zinc, selenium, iron, T3, T4, and TSH were measured. The correlation of qualitative variables was examined using the chi-square test, and the correlation of quantitative variables was examined using Spearman's correlation analysis. The t-test was used to compare the means in two different groups with the standard value. The generalized estimating equation (GEE) test was used to investigate the effect of time and compare the two groups. Statistical analysis of the data was performed in SPSS v. 22.

 The levels of iron, zinc, selenium, and thyroid hormones changed during the examined days, but these changes were not statistically significant. The amount of the analyzed elements in some cases was lower than their standard serum average, but this difference was significant only for selenium. Besides, there was no significant relationship between iron, zinc, T3, TSH, and the length of stay at the ICU; this relationship was positive and significant only for T4.

 Burn patients in the ICU have insufficient intake of minerals. Changes occur in the serum levels of micronutrients in these patients, affecting their physiological conditions and reducing the speed of recovery.

  The hypermetabolic response has undoubtedly evolved to help survive burns, but this physiological response has inconsistent consequences and increases the clinical consequences, such as increased heart work and ultimately its decline, decreased immune system function, risk of  sepsis, increased long-term  hospitalization, which increases the mortality of patients. This study aims to examine the effect of propranolol on post-traumatic stress disorder and clinical outcomes in burn patients. 

  This was an open-labeled randomized clinical trial in a single center with two parallel groups without placebo control. Propranolol was given 48 hours after starting of resuscitation. 

  In this study, the burn wound of the patients who used propranolol healed faster. In addition, the administration of propranolol reduced the size of the burning surface, the size of the tissue required skin graft, the rejection rate of skin grafts, and also the length of stay in the hospital. 

  Using propranolol in treating burns can play an influential role in the recovery of burn patients,  and reduce the post-traumatic stress disorder.

Treating burn scar contractures remains challenging for reconstructive surgeons; no clear guidelines declare the optimal and most effective technique. We evaluated the efficacy of local flaps in treating patients with post-burn contractures.

This retrospective study included 243 patients with post-burn contractures referred to Taleghani Hospital (Khuzestan, southwest Iran) for local flap reconstruction from 2011 to 2020. Patients' demographic data, detailed descriptions of scars, surgical procedures, and flap outcomes were assessed. A plastic surgeon conducted all surgical procedures, the goals of which were to release the scar and cover the defect. Joint range of motion (ROM) (according to goniometric measurements), complications, need for second-stage surgery, and patient satisfaction were assessed.

After scar release, 70.4% of joints were covered with a Z-plasty and similar local flaps, 26.1% with a Z-plasty plus skin grafts, and 3.5% with only skin grafts. The outcome after one year revealed a significant improvement in mean ROM (by 45.80% of the normal ROM; P< 0.001). The mean functional and aesthetic satisfaction scores were 9.45 and 7.61 out of 10, respectively. The complication rate was 10.82%: re-contracture occurred in 3.82%, flap tip necrosis in 1.27%, and partial flap necrosis in 0.31%.

Simple local flaps such as the Z-plasty are safe and effective in covering the joint following post-burn contracture release. Due to the feasibility, minimal need for facilities, steep learning curve, acceptable functional and aesthetic outcomes, and low complication rate, we strongly recommend the Z-plasty for reconstructing burn contractures, particularly in LMICs.

Burns and their resulting wounds are a global injury. Finding natural ingredients to speed up wound healing in patients with fewer side effects can be valuable. The aim of this study was to evaluate the oral effect of extract of Centella Asiati on pain and the healing process of burn wounds.

This study is a clinical trial in which 76 patients admitted to the burn ward were included in the study after considering the inclusion criteria and were randomly divided into two groups of intervention (n = 38) and control (n = 38). Patients' wounds were first examined on the seventh and fifteenth days with the Bets-Jensen instrument. The intervention group, in addition to the usual antibiotic treatments, received capsules containing 200 mg of Centella Asiati twice daily (8 am and 8 pm) and the control group received capsules containing 200 mg of starch twice daily. The results were analyzed using descriptive statistics and inferential statistics and SPSS statistical software.

The mean burn pain score after consuming Centella asiatica extract showed a significant improvement in the intervention group compared to the control group (p<0.001). The average wound healing score in the intervention group compared to the control group did not show significant improvement compared to the control group (p<0.561). However, size (p<0.561), undermining (p<0.023), necrotic tissue amount (p<0.015) and tissue granulation (p<0.001) had improved significantly in the intervention group. In addition, the results showed that Peripheral tissue edema (p<0.008) in the control group had a significant decrease compared to the intervention group.

According to the results of this study, the oral Centella asiatica extract reduced pain in patients with burn, however, it did not affect wound healing, although it improved a number of wound healing indicators. Similar studies on larger sample using other wound measurement tools are recommended.

Pilates is a sport that may play a role in reducing pain and healing burns faster like other sports, but these effects have not been investigated in a study. Therefore, this study aimed to investigate the effect of Pilates exercise on pain control and wound healing among patients with second-degree burns.

This randomized clinical trial in which 64 patients were randomly divided into intervention, and control groups was conducted in 2019 in Amir al-Momenin Burn Injury Hospital in Shiraz, Iran. Intervention group patients received 12 sessions of 45 to 60 minutes of Pilates exercise individually and control group patients received routine care. In both groups, pain was assessed once before and 11 times after the intervention using the Visual Analogue Scale. Like pain, wound healing was assessed in both groups once before and 7th day and 14th days after the intervention using the Bets-Jensen Wound Healing Questionnaire. The data were analyzed using SPSS 21 software.

In all times of the measurement, the mean of pain score and wound healing after the intervention were significantly improved in intervention group than control group (p< 0.05).

Pilates exercise improves pain and burn wound healing in burned patients and it can be considered as a complementary intervention in the management of pain and wounds among patients with second-degree burns by health care providers.