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عضویت

جستجوی مقالات مرتبط با کلیدواژه « dysphonia » در نشریات گروه « پزشکی »

  • Akbar Banari, Alireza Aghaz, Arash Shahriyari*, Fatemeh Fakhimi
    Objectives

    COVID-19 was triggered by the severe acute respiratory syndrome coronavirus-2, leading to a pandemic. The risk of developing dysphonia and dysphagia amongst COVID-19 patients is considered to be high.

    Methods

    In this prospective study, 150 patients affected by COVID-19 admitted to the intensive care unit (ICU) and the ward of Firoozgar Hospital in Tehran, Iran, were analyzed. Dysphagia and dysphonia were evaluated according to the swallowing impairment score and the consensus auditory-perceptual evaluation of voice (CAPE-V). Also, the quality of life (QoL) was measured using the Persian version of the voice handicap index, the swallowing QoL and the Persian version of the dysphagia handicap index (DHI).

    Results

    A total of 150 COVID-19 patients (mean age: 59.64±17.87 years and 54.3% male; 75 admitted patients to the ICU and 75 patients admitted to the ward) were evaluated. A total of 115(77%) patients with COVID-19 were experiencing dysphagia, and the prevalence of dysphagia did not vary meaningfully between the two sets. According to the swallowing QoL, the QoL of the two groups was meaningly different (P<0.05). Also, the QoL of patients admitted to the ICU was lower than those admitted to the ward. A total of 91(61%) COVID-19 patients had dysphonia and dysphonia prevalence was significantly varied among the two groups (P<0.05). Investigating the relationship between dysphagia severity, dysphonia severity, and age showed a significantly positive correlation (P<0.01). However, the length of stay had a positive correlation only with the severity of dysphonia (P<0.05). Also, a negative correlation was found between swallowing QoL, dysphagia severity, and dysphonia severity (P<0.01).

    Discussion

    Dysphagia and dysphonia were prevalent among COVID-19 patients and more common in older patients. Early evaluation is required for timely and efficient intervention to avoid further complications and to progress their QoL.

    Keywords: COVID-19, Dysphagia, Dysphonia, Prevalence, Intensive Care Unit (ICU), Predictor}
  • Akbar Banari, Alireza Aghaz*, Arash Shahriyari, Saeed Noori, Mahsa Pourmohammadi
    Introduction

    The world has been suffering from COVID-19 since 2020 and the disease continues up to now. COVID-19 patients are at high risk of dysphagia and dysphonia. Accordingly, this study aims to determine the prevalence of dysphonia and dysphagia and identify correlated factors to develop dysphagia and dysphonia in COVID-19 patients admitted to intensive care units (ICU).

    Materials and Methods

    A total of 70 patients with COVID-19 (Mean±SD age of 63.1±18.6; males=39) hospitalized in ICUs were evaluated by an expert on speech and language. The patients were evaluated for swallowing disorder via the Mann assessment of swallowing ability and the Persian version of the functional oral intake scale. The consensus auditoryperceptual evaluation of voice was also used to evaluate voice disorders.

    Results

    Overall, 58.6% of patients presented dysphagia and 74.3% of patients had dysphonia. Meanwhile, 34.3% of the patients were on mechanical ventilation. A correlation was detected between dysphagia severity and the number of mechanical ventilation days, the length of stay, and age (P<0.05). Dyspnea impacts the prevalence of dysphonia and dysphagia in COVID-19 patients (P<0.05). Vomiting has been effective on only the prevalence of dysphagia (P<0.05). Furthermore, a significant correlation was found between dysphagia and dysphonia (P<0.01).

    Conclusion

    A high prevalence rate of dysphagia and dysphonia exists in patients with COVID-19 admitted to ICUs. An early evaluation by a speech and language pathologist is essential to identify the suspected patients and provide early intervention to prevent further complications and improve their quality of life.

    Keywords: Prevalence, COVID-19, Dysphagia, Dysphonia, Intensive care unit}
  • Saeed Saeedi, Mahshid Aghajanzade, AhmadReza Khatoonabadi *
    Background

    Recent years have seen the development of voice indices for multi-parametric objective voice evaluation. The current study aims to review these indices and examine their efficiency through the literature.

    Methods

    The study design is a literature review. The five databases of ‘PubMed’, ‘Scopus’, ‘Google Scholar’, ‘Science Direct’, and ‘Web of Science’ were searched using the keywords ‘voice index’, ‘acoustic’, ‘voice assessment’, and ‘acoustic analysis’. Attempts were made to include only the acoustic indices that have been validated and are fairly user-friendly.

    Results

    Five voice indices were found that met the inclusion criteria: Dysphonia Severity Index (DSI), Acoustic Voice Quality Index (AVQI), Cepstral Spectral Index of Dysphonia (CSID), The Acoustic Breathiness Index (ABI), and Acoustic Psychometric Severity Index of Dysphonia (APSID).

    Conclusions

    The results suggest using AVQI, ABI, DSI, and CSID in the evaluation and treatment of voice disorders. Of course, it is recommend to examine the efficacy of these indices in more languages and also developing new indices by considering more aspects of voice.

    Keywords: Voice, Voice disorders, Dysphonia, Voice Quality, Acoustics}
  • Anupriya Ayyaswamy, Prasanna Kumar Saravanam, Latha Sneha *, Sandhya Sundaram
    Introduction

    Head and neck is the second most common region for lymphomas. Extranodal lymphomas of the larynx are rare in the pediatric population. Non Hodgkin Lymphoma (NHL) of the larynx is common in the supraglottic region as its rich in lymphoid tissue. They may present with dysphagia, dysphonia, snoring and progressive respiratory distress. Early visualization of the larynx is essential in such cases for appropriate diagnosis to improve the survival rates.

    Case Report:

    We present a case of 9 year old boy who presented with a change in voice, snoring and feeding difficulties for one year. Video laryngoscopy revealed globular mass arising from the epiglottis. He underwent excision biopsy and by immunohistochemistry was diagnosed to have diffuse large B cell lymphoma. He was treated with chemotherapy and the child is clinically well in the follow-up, 1 year after the completion of therapy.

    Conclusions

    Although primary lymphomas of the larynx in children are rare, a high index of clinical suspicion is warranted to avoid diagnostic delays to initiate appropriate management to have better outcomes.

    Keywords: Child, Dysphonia, Lymphoma, Larynx, Snoring}
  • Alireza Aghaz, Arash Shahriyari, Shiva Panahiaboozar, Hossein Jadidi, Mohadeseh Khoshgoftar, Edris Choupani, Ehsan Hemmati
    Introduction

    This study aimed to estimate the prevalence of dysphonia in patients with COVID-19.

    Materials and Methods

    English and Persian studies that reported dysphonia in patients with COVID-19 were included. Review and case report studies were excluded. We searched Web of Science, PubMed, Google Scholar, and Scopus from January 1, 2020, to July 15, 2021. The prevalence of dysphonia was obtained by combining the results and weighing the sample sizes in the corresponding studies. Heterogeneity was evaluated using the Cochran Q test and I2

    Results

    Of the 1830 articles identified, 7 studies (n=1410 patients) were included in the meta-analysis. The pooled prevalence of dysphonia was 31% (%95CI: 13%-48%). The prevalence rates of dysphonia in men and women with COVID-19 were 28.2% (%95CI: 14%-46%) and 32.8% (%95CI: 22%-45%), respectively.

    Conclusion

    Because of the design of the included studies, the reliability of the results is limited. There was notable heterogeneity in the data, not because of publication bias, but rather the small sample sizes or the heterogeneity of the COVID-19 disease. About one-third of patients with COVID-19 may have dysphonia as the only symptom. Therefore, one should even be careful in approaching those who have only dysphonia.

    Keywords: Prevalence, Dysphonia, Voice, COVID-19, Meta-analysis, Review}
  • Mahshid Aghajanzadeh, Saeed Saeedi *
    Introduction

    The acoustic analysis is one of the well-known methods for voice evaluation. In recent years, many studies have investigated the cepstral measures compared with the other former acoustic parameters. This review article evaluates the related studies in the cepstral areas to ascertain whether they are efficient in the diagnosis of dysphonia.

    Materials and Methods

    We reviewed the available research studies between 2009 and 2021 narratively in PubMed, Scopus, Google Scholar, and Science Direct databases. The searched keywords included “cepstral peak prominence”, “smoothed cepstral peak prominence”, “instrumental acoustic analysis”, “acoustic”, and “diagnosis”. The articles that investigated the power of Cepstral Peak Prominence (CPP) and its smoothed version (CPPS) to differentiate dysphonia versus normal voice have been included. However, the interventional studies that consider CPP and CPPS as one of their adjunct variables and studies that investigated the relationship of the cepstral measure with other parameters were not included.

    Results

    Recent studies support the efficiency of CPP and CPPS to diagnose dysphonia.

    Conclusion

    It is reasonable for the voice care teams to use CPP and CPPS in the patients’ initial assessment and track the effects of treatment. However, according to the relatively limited number of studies in this area, more studies are required to clarify the efficacy of cepstral measures in different voice pathologies.

    Keywords: Voice, Voice disorders, Dysphonia, Voice quality, Acoustics}
  • Mostafa Solati, Majid Dadmehr, Abdolghader Bahraini, Reza Samarei, HamidReza Khalkhali, Omid Sadeghpour *

    Dysphonia is a common voice disorder that affects about one-third of the population at some point in their lives.1 The terms dysphonia and hoarseness are frequently used interchangeably. However, dysphonia is a disorder characterized by changes in vocal quality, pitch, and loudness or vocal effort. Patients with dysphonia are unable to communicate properly, and their voice-related quality of life (VR-QOL) is negatively affected.

    Keywords: Dysphonia, Herbal medicine, Diet, Avicenna}
  • Hamid Azadi, Mohammad R Akbarzadeh T, Ali Shoeibi, HamidReza Kobravi

    Background: Parkinson’s disease (PD) is a neurological disorder caused by decreasing dopamine in the brain. Speech is one of the first functions that are disrupted. Accordingly, speech features are a promising indicator in PD diagnosis for telemedicine applications. The purpose of this study is to investigate the impact of Parkinson’s disease on a minimal set of Jitter and Shimmer voice indicators and studying the difference between male and female speech features in noisy/noiseless environments. Materials and Methods: Our data includes 47 samples from nursing homes and neurology clinics, with 23 patients and 24 healthy individuals. The optimal feature for each category is studied separately for the men’s and women’s samples. The focus here is on the phonation in which the vowel/a/is expressed by the participants. The main features, including Jitter and Shimmer perturbations, are extracted. To find an optimal pair under both noisy and noiseless circumstance, we use the Relief feature selection strategy. Results: This research shows that the Jitter feature for men and women with Parkinson’s is 21 and 33.4, respectively. While the Shimmer feature is 0.1 and 0.06. In addition, by using these two features alone, we reach a correct diagnosis rate of 79% and 81% for noisy and noiseless states, respectively. Conclusion: The PD effects on the speech features can be accurately identified. Evaluating the extracted features suggests that the absolute value of the selected feature in men with PD is higher than for healthy ones. Whereas, in the case of women, this is the opposite.

    Keywords: Classification, dysphonia, Parkinson disease, phonation, speech disorders}
  • Gamal Youssef *, Bassam Mahboub, Safinaz Azab
    Introduction
    Laryngeal tuberculosis (LTB) is the most frequent granulomatous disease of the larynx. The aim of the present work was to study the laryngostroboscopic features and voice quality of patients with laryngeal TB secondary to pulmonary TB.  
    Materials and Methods
    Participants were 35 patients diagnosed as having pulmonary TB and dysphonia. All patients had a complete history, clinical and laboratory workup. Patients were assessed using a protocol of voice assessment which included Auditory-perceptual analysis of voice, voice analysis using the Multidimensional Voice Profile (MDVP), and laryngostroboscopy.  
    Results
    The participants were 24 males and 11 females and their mean age was 43.7 years. The voice acoustic analysis revealed a significant difference from normal in jitter percent, shimmer percent, and harmonic to noise (H/N) ratio. Laryngeal gross lesions were found in 11 patients while the other 24 patients had normal laryngoscopic findings with nonspecific stroboscopic changes as reduced mucosal waves and mild glottic gap. Diffuse lesion of the whole vocal folds was found in 5 patients and anterior predilection in 4 patients. The type of lesions were granulomatous lesions in 7 patients and non-specific inflammatory mild exophytic lesions in 4 patients.      
    Conclusions
    Voice disorders in pulmonary TB include disturbance in the mechanism of voice production with or without detectable laryngeal lesion. Videostroboscopy has the advantage of showing the extension of laryngeal involvement, vocal folds vibrations, and mucosal waves.
    Keywords: Dysphonia, Laryngeal Tuberculosis, Laryngostroboscopy, Pulmonary TB}
  • Somayeh Kasefy, Farhad Torabinezhad*, Mahboobeh Rasouli, Bentolhoda Zareifaskhodi, Arezoo Saffarian
    Objectives

    Voice is influenced by personality. However, it is still questionable which acoustic features are influenced by personality traits. This study aimed to investigate the relationship between acoustic characteristics and personality dimensions.

    Methods

    Thirty-three participants with dysphonia and 33 participants without dysphonia were recruited to take part in this cross-sectional study. Personality dimensions were evaluated by the revised NEO personality inventory, and acoustic characteristics by using the Praat software. The tasks included prolongation of the vowel /a/, expression of declarative and interrogative sentences, reading, and connected speech. The acoustic features included fundamental frequency range, jitter, shimmer, harmonic-to-noise ratio, intensity, and duration. SPSS V. 23 was used for statistical analysis. For correlation analysis, the Pearson and Spearman correlation coefficients were employed.

    Results

    In individuals with dysphonia, a significant relationship was observed between personality dimensions and the following acoustic features: A. extraversion and intensity in connected speech (P=0.045) and the reading task (P=0.036); B. openness and shimmer in /a/ vowel prolongation (P=0.003); C. openness and the harmonic-to-noise ratio in /a/ the vowel prolongation task (P=0.017); and D. agreeableness and duration in expressing interrogative sentences (P=0.019).

    Discussion

    In Persian-speaking participants with and without dysphonia, some acoustic characteristics were significantly correlated with the mean score of the personality test (revised NEO personality inventory). It seems that each voice feature is influenced by personality dimensions. This finding indicates that changes in acoustic characteristics of voice due to personality can be evaluated in laboratory and hearing examinations.

    Keywords: Voice, Dysphonia, Personality, Acoustics}
  • Geun, Hyo Kim, Soo, Geun Wang, Yeon, Woo Lee, Soon, Bok Kwon*
    Introduction
    Laryngeal burns cause long-term voice disorders due to mucosal changes of the vocal folds. Inhalation injuries affect voice production and result in changes in the mucosal thickness and voice quality.

    Case Report: A 47-year-old woman was transferred to our department with laryngeal burns sustained during a house fire. On laryngoscopic examination, mucosal waves of both vocal folds were not visualized due to the injury caused by inhalation of high-temperature toxic smoke. Hence, voice analysis, laryngoscopic examinations, and high-speed videoendoscopy (HSV) were performed to evaluate vocal fold vibrations. An absence of mucosal waves and a breathy and strained voice with a severe grade were noted. We report that voice quality was recovered to close to the normal state through multiple treatments such as medication, voice therapy, and counseling.
    Conclusion
    This paper presents the unique case of a patient with laryngeal burns, in which vibrations of the vocal folds were observed using laryngoscopic examination and HSV. Voice samples before and after treatment were also analyzed. By observing the vibration pattern of the injured vocal fold, it is expected that appropriate diagnosis and treatment planning can be established in clinical practice.
    Keywords: Dysphonia, Inhalation Burns, Larynx, Laryngoscopy}
  • Amin Rezaee Rad, Negin Moradi *, Mohammad Jafar Shater Zadeh Yazdi, Majid Soltani, Mohammad Mehravar, Seyyed Mahmood Latifi
    Objectives
    The aim of this study was to evaluate the effects of manual circumlaryngeal therapy after one session of treatment on the voice of patients with muscle tension dysphonia.
    Methods
    A total of 20 patients with muscle tension dysphonia were evaluated by recording vowel /a/ phonation and extracting fundamental frequency (F0), first formant frequency (F1), jitter, shimmer, and harmonics-to-noise ratio (HNR). One session of manual circumlaryngeal therapy was held for these patients. Immediately after treatment, acoustic assessments were replicated.
    Results
    Following manual circumlaryngeal therapy, jitter and shimmer showed a significant reduction (P
    Conclusions
    The reduction in jitter and shimmer and increase in HNR after therapy resulted in the patients’ vocal improvement. Reduction of F1 after treatment suggests elongation of vocal tube and elimination of vocal tract shortness in response to the descent of larynx from its high-tension status. The insignificant change of F0 was attributed to the lack of change in vibrational characteristics, as well as stretching of vocal cords.
    Keywords: Therapy, Dysphonia, Acoustic, Voice}
  • Seyyedeh Maryam Khoddami *, Nazila Salary Majd
    Introduction
    This study aimed to investigate construct convergent validity of the Persian version of consensus auditory perceptual evaluation of voice (called ATSHA), using the acoustic measurements. Moreover, the effect of voice tasks on the perceptual ratings was studied.
    Materials and Methods
    The study data were gathered from a total of 40 dysphonic patients (Mean±SD age=36.79±8.26 years). Perceptual voice evaluation was performed using the ATSHA during sustained vowels and sentence reading tasks. The acoustic features including fundamental frequency (F0), intensity, jitter, shimmer, and Harmonics-to-Noise Ratio (HNR) were extracted using Praat application. To assess construct validity of ATSHA, correlation between perceptual and acoustic measures were studied. The effect of tasks was investigated by mean comparison and Pearson correlation.
    Results
    The results demonstrate that ATSHA has significant correlation with all acoustic measures except the frequency (r=-0.08-0.35; P≥0.05). There was no significant correlation between pitch and the acoustic measures of intensity and jitter (r=-0.31; P=0.05 and r=0.24; P=0.14, respectively). The highest correlation observed between the overall severity and the HNR (r=-0.85; P<0.001). The correlation between the perceptual scores in both tasks was high (r=0.82-0.99, P<0.05).
    Conclusion
    The ATSHA is a valid scale for perceptual judgment on intensity, jitter, shimmer, and HNR. However, this scale could not estimate the frequency of voice in dysphonia. The current study demonstrate that vowel prolongation and sentence reading has no noticeable effect on the perceptual ratings in dysphonia.
    Keywords: Auditory perception, Acoustic, Voice, Dysphonia}
  • مرضیه استادی، فاطمه ابناوی، آصفه معماریان، پریسا احمدی، عاطفه دارویی فرد، پریزاد جانقربان
    هدف
    معلمان یکی از بزرگترین گروه های کاربران حرفه ای صوت هستند که از صوتشان به عنوان ابزار اولیه برای حرفه شان استفاده می کنند. بنابراین در معرض خطر بالایی برای ابتلا به اختلالات صوت هستند. هدف از این مطالعه تعیین میزان همبستگی میان نمرات کلی دو مقیاس فارسی VHI و V-RQOL قرار گرفت. اطلاعات زمینه ای از طریق پرسشنامه و تحلیل نمونه صوت جمع آوری گردید.
    روش بررسی
    این پژوهش یک مطالعه توصیفی تحلیلی بود که به صورت مقطعی انجام گردید. جامعه مورد مطالعه معلمان ابتدایی شاغل در شهر اصفهان بودند که از میان آنها 32 معلم ابتدایی مبتلا به اختلال صوت از طریق نمونه گیری در دسترس مورد بررسی قرار گرفتند. هر آزمودنی فرم های VHI و V-RQOL را تکمیل نمود. داده های بدست آمده با آزمون آماری همبستگی پیرسون مورد بررسی قرار گرفت.
    یافته ها
    نتیجه مطالعه نشان داد که میان نمرات کلی دو مقیاس VHI و V-RQOL در میان معلمان مبتلا به اختلال صوت همبستگی معنادار منفی وجود دارد (0٫876-=r؛ 0٫001>p).
    نتیجه گیری
    بنظر می رسد در کار بالینی متخصص می تواند براساس نظر خویش هر یک از این مقیاس ها را استفاده نماید و نیازی به استفاده از هر دو نیست.
    کلید واژگان: معلم, کیفیت زندگی, اختلال صوت, پرسشنامه, VHI, V, RQOL}
    Marzieh Ostadi, Fatemeh Abnavi, Asefeh Memarian, Parisa Ahmadi, Atefeh Darooyifard, Parizad Janghorban
    Background
    Teachers, as professional voice users, are at high risk of voice disorders. The greater their dependency on voice as a means of social and professional satisfaction, the worse the effects of voice disorders on the quality of their lives. Voice complaints may have a great impact on the quality of teachers’ lives. There are no self-appraisal protocols for teacher's quality of life. Therefore, little is known about how valid the Persian version of VHI and V-RQOL scales are. It is also unknown which of the aforementioned scales best describes the effect of voice disorder on the population under investigation. As such, it is important to know to what extent the aforementioned scales correlate with each other. Therefore, the aim of this study was to calculate the correlation between total scores of the Persian versions of VHI and V-RQOL scales administered to teachers with voice disorders.
    Method and Materials: This study was a cross-sectional descriptive-analytical one. The participants were 32 female primary teachers with voice disorders recruited through available sampling. In order to confirm that the participants suffer from voice disorders, they were asked to express the sound /a/ with their habitual pitch and loudness for a period of 7 seconds. Sound samples were recorded, while environmental noise was controlled (less than 50 dB). In the next step, the acoustic parameters (F0, SD F0, NNE, HNR, Shimmer and Jitter) were investigated in a 5 second interval of recorded sound using Praat software. If the values of the acoustic parameters were higher than normal, the sample was judged as abnormal. Then the teachers with a disordered voice sample were asked to read and complete the Persian version of the VHI and V-RQOL forms carefully. The normality of data distribution was tested by using Shapiro-Wilkes test and the correlation between the total score of the two questionnaires was assessed by Pearson's correlation test.
    Results
    Shapiro-Wilkes test showed that the data was normally distributed. The correlation between the total score of VHI and V-RQOL was assessed using Pearson's correlation test. The results revealed a significant correlation between the overall scores of the participants on VHI and V-RQOL scales (r=-0.876, p
    Conclusion
    Since a significant negative correlation exists between the scores gained by teachers with voice disorders on the VHI and V-RQOL questionnaires, it is concluded that both questionnaires measure the same feature (voice related quality of life). So, it is suggested that experts in clinical practice should use either of the two scales as they wish. In other words, there is no need to use both of them.
    Keywords: Teacher, quality of life, dysphonia, questionnaires, VHI, V-RQOL}
  • Swati Maldhure, Ramanathan Chandrasekharan*, Amit, Kumar Dutta, Ashok Chacko, Mary Kurien
    Introduction
    Laryngopharyngeal reflux (LPR) is considered an important cause of voice disorder. We aimed to determine the frequency of LPR in patients with voice disorder and the association between Koufman Reflux Symptom Index (RSI), Reflux Finding Score (RFS), gastroesophageal reflux disease (GERD), and proximal acid reflux in these patients.
    Materials And Methods
    We performed a prospective study in patients aged more than 18 years presenting at the ear, nose, and throat (ENT) clinic with a change in voice lasting more than 3 weeks. All patients underwent nasopharyngolaryngoscopy and a dual-probe esophageal pH study. LPR was diagnosed by a Koufman RSI of >13 and/or RFS of >7. GERD was diagnosed according to a DeMeester Johnson score of >14.7. Proximal acid reflux was diagnosed if acid exposure time was >0.02% in a proximal pH probe.
    Results
    The study included 30 patients with a voice disorder. The mean age of participants was 38.5 years and 40% of patients were female. Using either of the two criteria, LPR was present in 46.7% of patients, half of whom had GERD. Among the remaining 53.3% patients with a voice disorder and no evidence of LPR, GERD was present in 25%. There was no significant association between the presence of LPR based on RSI (P=1) and GERD or RFS and GERD (P=0.06). Proximal acid reflux was present in only 10% patients with a voice disorder, and there was no significant association of this test with RFS (P=1) or RSI (P=1).
    Conclusions
    Approximately half of the patients with a voice disorder have LPR, and only a subset of these patients have evidence of GERD. Fiberoptic laryngoscopic findings (RFS) complementing RSI appears to be important in diagnosing possible reflux etiology in voice disorders and can be an indicator for instituting anti-reflux therapy. However, there is no significant association between RSI, RFS, and GERD suggesting that these tests evaluate different features of the disease. Proximal acid reflux is uncommon in patients with voice disorder based on current measurement criteria. Acid exposure time as measured in the proximal probe of a 24-hour dual pH probe may need to be re-evaluated as one of the diagnostic criteria for LPR.
    Keywords: Dysphonia, Esophageal pH Monitoring Received, Gastroesophageal Reflux, Laryngopharyngeal Reflux}
  • Abbas Tafakhori, Alvin Yu Jin Ng, Sumanty Tohari, Byrappa Venkatesh, Hane Lee, Ascia Eskin, Stanley F. Nelson, Carine Bonnard, Bruno Reversade, *Ariana Kariminejad
    Background
    TWINKLE (c10orf2) gene is responsible for autosomal dominant progressive external ophthalmoplegia (PEO). In rare cases, additional features such as muscle weakness, peripheral neuropathy, ataxia, cardiomyopathy, dysphagia, dysphonia, cataracts, depression, dementia, parkinsonism, and hearing loss have been reported in association with heterozygous mutations of the TWINKLE gene.
    Methods
    We have studied a large Iranian family with myopathy, dysphonia, dysphagia, and behavior change in addition to PEO in affected members.
    Results
    We identified a missense mutation c.1121G > A in the c10orf2 gene in all affected members. Early death is a novel feature seen in affected members of this family that has not been reported to date.
    Conclusion
    The association of PEO, myopathy, dysphonia, dysphagia, behavior change and early death has not been previously reported in the literature or other patients with this mutation.
    Keywords: Dysphonia, myopathy, ptosis, progressive external ophthalmoplegia, TWINKLE}
  • Mohsen Rajati, Shirin Irani, Ehsan Khadivi, Mehdi Bakhshaee
    Introduction
    Foreign bodies in the upper airway are one of the most challenging otolaryngology emergencies and have various presentations depending on their physical properties and location. Leeches are blood-sucking hermaphroditic worms that vary in color, length, and shape. They usually reside in fresh-water streams and lakes. When rural untreated water is drunk, leeches may localize in the nose, pharynx, and esophagus, or rarely in the larynx. CaseReport: This case is a man who was referred to our otolaryngology clinic with a complaint of hemoptysis and mild respiratory distress. The patient’s symptoms were all relieved post operatively and he was discharged on the second day following the procedure.
    Conclusion
    Leeches should be suspected as an airway foreign body in patients with a recent history of drinking stream water.
    Keywords: Dysphonia, Hemoptysis, Leech}
  • Keyvan Kiakojury, Mehdi Dehghan, Fateme Hajizade, Soraya Khafri
    Introduction
    Laryngeal dysfunction may be divided into three categories; organic, neurologic and functional disorders. Dysphonia and hoarseness are the most common symptoms and, in some cases, the only signs of laryngeal dysfunction. In differential diagnosis of any type of chronic hoarseness, a neoplastic process must be considered and, thus continuous light video laryngoscopy can provide important information on the presence of neoplastic lesions in order to prevent disease progression via early detection and action.
    Materials And Methods
    This cross-sectional, descriptive-analytical study was carried out on 197 patients with voice disorders admitted to Ayatollah Rouhani Hospital for video laryngoscopy. Available sampling was used and the results achieved were analyzed using SPSS17 statistical software.
    Results
    A total of 197 patients (mean age, 40.72 ±15.17 years) participated in this study, 56.9% of whom were male. From analysis of video laryngoscopy, organic dysphonia was found to be the most common cause of voice disorders, while functional and neurologic dysphonia were observed in 8.6% and 5.6% of patients, respectively. Vocal nodules and Reinke''s edema were among the most common causes of organic dysphonia, with a frequency of 24.4% and 23.4%, respectively; while laryngeal carcinoma accounted for 2.5% of all diagnosed cases with organic causes.
    Conclusion
    Since the presence of voice disorders for more than 3 weeks can be a sign of laryngeal dysfunction, early diagnosis using noninvasive methods such as video laryngoscopy and appropriate medical measures can help prevent the disease progression and eliminate the need for actions such as laryngectomy.
    Keywords: Dysphonia, Hoarseness, laryngeal video endoscopy (video laryngoscopy), laryngeal neoplasm}
  • علیرضا رجایی*، سعید تیموری، علیرضا غفرانی، سمانه طاهری زاده
    هدف
    هدف پژوهش حاضر مقایسه ویژگی های شخصیتی زنان مبتلا به گرفتگی کارکردی صدا با زنان سالم بود.
    روش
    27 زن مبتلا به گرفتگی کارکردی صدا و 44 زن سالم، که از نظر سن، تحصیلات، شغل و وضعیت تاهل با گروه بیماران همتا شده بودند، بررسی شدند. با کاربرد تکنیک ویدیو- لارنگوسکوپی و مصاحبه، ارزیابی ادراکی صوت از نظر بهنجار و نابهنجار بودن انجام شد. هر دو گروه فرم کوتاه پرسشنامه پنج عاملی نئو را تکمیل کردند. داده ها با آزمون t مستقل تحلیل شد.
    یافته ها
    یافته ها نشان داد زنان مبتلا به گرفتگی کارکردی صدا در روان رنجورخویی (002/0=p) و مسئولیت پذیری (001/0=p) نمره بالاتر و در برون گرایی (002/0=p) و توافق (001/0>p) نمره پایین تری داشتند.
    نتیجه گیری
    زنان مبتلا به گرفتگی کارکردی صدا در برخی ویژگی های شخصیتی با زنان سالم تفاوت دارند. این موضوع ممکن است در تشخیص علت اختلال و ارائه راهکارهای درمانی بهینه مفید باشد.
    کلید واژگان: ویژگی شخصیتی, اختلال گرفتگی صدا, اختلال صوت}
    Ali Reza Rajaei *, Saeid Timoree, Ali Reza Ghofranee, Samanah Tahereizadah
    Objectives
    This study aim was comparison of the personality characteristics of women with functional dysphonia (FD) with a healthy control group.
    Method
    Twenty-seven women with FD and 43 healthy women matched for age، education، occupation and marital status of FD group were investigated. Using videolaryngoscopic technique and interview، the perceptual appraisal of voice for standard or non-standard status was conducted. Both groups completed the NEO Five-Factor Inventory (NEO-FFI). Data were analyzed by independent t-test.
    Results
    The women with FD had higher scores in neuroticism (p=0. 002) and conscientiousness (p=0. 001) and lower scores in extraversion (p=0. 002) and agreeableness (p≤0. 000).
    Conclusion
    The women with FD are differentiated from healthy women in some personality characteristics. These findings seem useful in identification of the etiology of functional dysphonia and presenting optimum treatment strategies.
    Keywords: personality characteristics, voice disorder, dysphonia}
  • سیدجواد حسینی *، زهرا لله گانی، علی رامشینی
    زمینه و هدف

    کیفیت صدای معلم نقش مهمی در تفهیم مطالب درسی به دانش آموز دارد. خشونت صدا مهم ترین نشانه بیماری های حنجره است که بسیار شایع می باشد. هدف از این مطالعه بررسی میزان آگاهی و عوامل مرتبط با دیس فونی و همچنین میزان شیوع آن در معلمین دبستان های شهر یزد می باشد.

    مواد و روش ها

    این مطالعه مقطعی و از نوع توصیفی تحلیلی می باشد. حجم نمونه با استفاده از جدول مورگان، ورجسای 280 نفر تعیین شد. از پرسشنامه محقق ساخته جهت جمع آوری داده ها در خصوص متغیر آگاهی از دیسفونی علائم و میزان شیوع و نیز رفتارهای پیشگیری کننده به همراه متغیرهای دموگرافیک استفاده شد. داده ها پس از جمع آوری از طریق نرم افزار SPSS و آمار توصیفی و نیز آزمون های اسپیر من، تی تست، آنووا و آنالیز واریانس مورد تجزیه و تحلیل قرار گرفت.

    یافته ها

    میزان شیوع دیس فونی در معلمان 4/55 درصد و شایع ترین مشکل «خشک شدن گلو» بود. بین تحصیلات و میزان آگاهی رابطه معناداری وجود داشت (02/0p=). هر میزان سطح تحصیل بالاتر می شد؛ میزان آگاهی از دیس فونی نیز افزایش می یافت. همچنین نتایج نشان داد که بین جنس و ساعات تدریس رابطه معناداری از لحاظ آماری یافت شد (04/0p=). زنان بیشتر از مردان در خصوص عوامل پیشگیری کننده از دیس فونی اطلاعات داشتند (02/0p=). در بررسی رابطه رفتار پیشگیری کننده از دیس فونی و میزان آگاهی رابطه معناداری و مستقیم با ضریب اطمینان 99 درصد با ضریب همبستگی 30 درصد مشاهد شد. معلمان با نمره آگاهی بیشتر، رفتارهای پشگیری کننده بیشتری را نسبت به سایرین داشتند (001/0p=).

    نتیجه گیری

    با توجه به شیوع بالای این مشکل در معلمین دبستان های شهر یزد رفتارهای پیشگیری کننده از این اختلال بسیار ضعیف می باشد. لذا توصیه می شود با برگزاری کلاس های آموزشی از سوی متخصصین این امر میزان آگاهی و عملکرد معلمان جهت پیشگیری و کنترل این مشکل افزایش داده شود.

    کلید واژگان: دیس فونی, میزان آگاهی, رفتارهای پیشگیرانه, معلمین ابتدایی}
    Seyyedjavad Hosseini, Zahra Lalehgani, Ali Ramshini
    Background

    The quality of teacher’s voice has an important role in understanding lessons by the students. The roughness of the Noice is the most importantsign of darynx disease and one of the reasons of the spasm of Noice is the improper usage of the of the noice the object of this study is inverstigating rateof knowledge and prophydaxis behaviors from dissphoie and the rate of it’s outbreak in female teachers of Yazd’s elementary school.

    Materials And Methods

    This study is descriptive – analytie، and is done obout 280 teachers that were chosen from education areas casually. It used of questionnaire and interviewing for callectingdata.

    Results

    The rate of dissphonie’s outbreak between the teacherswas 55. 4% and the most epidemic form was stiffness of larynx. The rate of teachers’ knowledge was in average. There was a meaning full relationship between education and the rate of knowledge. Everyone that had a course of studies for associate of arts diplona and higher than it، had the higher rate of knowledge. There was a statical relationship between the age and the signs of spasm of noice also، it was seen a meaningful relationship between the employment background and prophydaxis behaviors from dissphorue. There was a direct meaningful relationship between the rate of knowledge and praphydoxis behaviors، and the teachers who had the higher rate of knowledge، choose further praphydoxis behaviors between the teachers of Yazd’s elementary schools oven though the outbreak of this farm is high and it’s suggested by holding the educating classes، the rate of knowledge and performance of the teachers have been in creased for preventing and controlling this problem.

    Keywords: Teachers, Dysphonia}
نکته
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