جستجوی مقالات مرتبط با کلیدواژه "paresthesia" در نشریات گروه "پزشکی"
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Background
We aimed to assess the satisfaction level of patients with the outcome of genioplasty and the influential parameters in this respect.
MethodsThis retrospective study was conducted on 70 patients between 18 to 59 years, who underwent genioplasty in the Oral and Maxillofacial Surgery Department at Shariati and Sina Hospitals, Tehran, Iran, between 2010 and 2020. Patient records were evaluated and a questionnaire was filled out over the phone to assess the influential parameters on the satisfaction level of patients with the outcome of genioplasty. Data were analyzed by PASS 11 (alpha=0.1).
ResultsSeventy patients were evaluated including 56 (80%) females and 14 (20%) males. Forty patients (52.6%) had no complaint with regard to the outcome of genioplasty. Postoperative chin deviation (not correcting the initial complaint) (10.52%), postoperative pain in the chin area (10.52%), and lower lip paresthesia (9.21%) were the most common patient complaints. The minimum and maximum satisfaction scores were 22 and 80, respectively. Number of follow-up sessions had a significant effect on satisfaction with the outcome of genioplasty (P=0.076). Patients who underwent advancement genioplasty alone had the highest level of long-term satisfaction with the outcome while those who underwent setback genioplasty alone had the lowest level of long-term satisfaction.
ConclusionAdvancement genioplasty had the highest rate of patient satisfaction, and chin asymmetry in the frontal view was the most common patient complaint after genioplasty.
Keywords: Genioplasty, Chin, Facial Asymmetry, Paresthesia, Patient Satisfaction, Orthognathic Surgery -
مقدمه
آسیب ایاتروژنیک به عصب آلویولار تحتانی از مواردیست که احتمال وقوع آن طی پراسیجر دندانپزشکی وجود دارد. در این مطالعه سه بیمار که به دنبال کار دندانپزشکی دچار آسیب به عصب آلویولار تحتانی و بدنبال آن پاراستزی لب و چانه ولثه مربوطه شده بودند، تحت درمان با تابش لیزر کم توان با فتوبایومدولیشن قرار گرفتند.
گزارش مورد:
مورد اول یک خانوم 56 ساله بود که بدنبال کشیدن دندان 7 چپ پایین و قرارگرفتن گرفت استخوانی دچار پاراستزی لب و چانه ولثه باکال شده بود و بعد از یک سال و نیم به این مرکز مراجعه کرده بود و با تشخیص پاراستزی مربوط به عصب آلویولار تحتانی (IAN) تحت درمان با فتوبایومدولیشن قرار گرفت. مورد دوم خانم 38 ساله که پس از قراردادن ایمپلنت در محل دندان 6 پایین دچار پاراستزی لب و چانه ولثه باکال بود. بلافاصله ایمپلنت خارج شد وبیمار پس از دو هفته تحت درمان فتوبایومدولیشن بصورت دو سیکل با فاصله 6 ماهه قرار گرفت. مورد سوم: بیمار یک خانم 29 ساله بود که پس از درمان ریشه دندان 6 پایین در یک جلسه، دچار پاراستزی لب و چانه و لثه باکال شد و دو هفته بعد تحت درمان فتوبایومدولیشن قرار گرفت. از طول موج لیزر دایود 980 نانومتر استفاده شد.ارزیابی با اندازه گیری و مقایسه حس لامسه و حس حرارتی قسمت آسیب دیده نسبت به قسمت سالم با مقیاس درد VAS انجام شد. هرسه بیمار گزارش کردند که طی جلسات درمان، حس در ناحیه کرختی بهترمی شد و پس از پایان درمان، بهبودی کامل و یا نسبی حاصل شد.
نتیجه گیریاز آنجایی که فتوبایومدولیشن در امتداد مسیر عصب دچار پاراستزی ، می تواند موجب تحریک رژنراسیون عصب آسیب دیده شود می توان آن را بعنوان روش درمانی بدون عوارض جانبی و غیر تهاجمی قابل قبول در نظر گرفت.
کلید واژگان: فتوبایومدولیشن تراپی, عصب آلوئولار تحتانی, تراما, پاراستزیBackgroundIatrogenic damage to the inferior alveolar nerve (IAN) is one of the possible complications that may occur during dental procedures. In this study, we examined three patients who suffered from IAN damage and lip paresthesia after receiving dental care and were then treated with photobiomodulation (PBM) therapy.
Case Report:
Case 1; a 56-year-old woman presenting with lip, chin and buccal mucosa paresthesia following the extraction of the left mandibular second molar and bone grafting. The patient admitted to our clinic after 18 months with the diagnosis of IAN related paresthesia and was treated with PBM therapy. Case 2; a 38-year-old woman reported sensory loss in lip, chin and buccal mucosa in the right quadrant after implant placement. Implant was removed immediately and after two weeks, patient underwent PBM treatment which was performed in two cycles that were 6 months apart. Case 3; A 29-year-old woman suffered from lip, chin and buccal mucosa paresthesia in the right site after receiving a single-visit mandibular molar root canal treatment. She underwent PBM therapy after two weeks. Diode 980 nm laser was used. Treatment outcomes were assessed by measuring the palpation and thermal sensation of the affected area using visual analogue scale (VAS). The obtained VAS scores were compared with those of the intact side of the mandible. All three patients reported that sensation in the numbed area improved during the treatment sessions and complete or partial recovery was achieved after the treatment period.
ConclusionSince PBM therapy is able to stimulate the regeneration of the damaged IAN, it can be considered as a non-invasive treatment option with minimal complications.
Keywords: Photobiomodulation therapy, Inferior Alveolar Nerve, Trauma, Paresthesia -
مجله دانشکده پزشکی دانشگاه علوم پزشکی تهران، سال هشتاد و یکم شماره 3 (پیاپی 266، خرداد 1402)، صص 168 -175زمینه و هدف
دیابت شایعترین علت نوروپاتی در جهان است و داروهایی مثل گاباپنتین برای درمان علامتی آن استفاده می شوند. داروی گیاهی نوروتک (Neurotec) (ترکیب نسترن وحشی، گزنه و تانسی) با افزایش سرعت انتقال پیام عصبی و ترمیم اعصاب محیطی می تواند در درمان این بیماری موثر باشد. هدف از این مطالعه مقایسه عوارض و اثربخشی داروی نوروتک بر کاهش علایم حسی نوروپاتی دیابتی با گاباپنتین می باشد.
روش بررسیدر یک کارآزمایی بالینی یک سوکور تعداد 100 بیمار دیابتی مراجعه کننده به کلینیک دیابت بیمارستان طالقانی کرمانشاه از فروردین تا شهریور سال 1397 به دو گروه تقسیم شدند، یک گروه روزانه mg 300-100 گاباپنتین وگروه دیگر روزانه mg 100 نوروتک دریافت کرده اند. در ابتدای مطالعه و در پایان هفته های 6 و12، از نظر شدت علایم حسی شامل پارستزی و درد با معیار DN4 questionnaire و معیار آنالوگ بصری VAS در دو گروه مقایسه شدند و نتایج به دست آمد و آنالیز شد.
یافته هانتایج نشان داد که نوروتک باعث کاهش احساس سرما، درد، پارستزی، شدت درد وVAS و DN4 می شود (به ترتیب مقدار P برابربا 01/0، 05/0، 05/0، 05/0، 001/0، 05/0). باوجود اختلاف دو گروه، تنها در کاهش شدت درد، داروی نوروتک برتری معناداری را نسبت به داروی گاباپنتین نشان داد و در سایر موارد تفاوت دو گروه قابل توجه نبود. تنها عارضه قابل توجه درمورد نوروتک بروز دل درد بود اما در گروه گاباپنتین، سرگیجه، خواب آلودگی و احساس گیجی از عوارضی بود که به صورت معناداری از گروه نوروتک بیشتر گزارش شد (05/0P>).
نتیجه گیریاستفاده از نوروتک می تواند باعث بهبود علایم حسی نوروپاتی دیابتی شود و عوارض جانبی شدیدی ندارد.
کلید واژگان: نوروپاتی دیابتی, گاباپنتین, نوروتک, پارستزیBackgroundDiabetes is the most common cause of peripheral neuropathy throughout the world and has negative impact on patient's quality of life. There is no cure and to date several drugs have been used for its symptomatic treatment, including antidepressants and antiepileptics. Neurotec is a herbal medicine (combination of wild star anise, nettle and tansy) that can be potentially effective in the treatment of this disorder. Proposed mechanisms include its effects on increasing nerve conduction velocity and repairing peripheral nerves.
MethodsIn a single-blind randomized clinical trial from April to September 2018 in Kermanshah of patients referred to Taleghani Hospital Clinic, 100 diabetic patients with sensory complaints, were randomly divided into two groups. The first group received 100 to 300 mg gabapentin (a well-known effective antiepileptic drug) daily and the second group received 100 mg Neurotec daily. At the beginning of the study and at the weeks of 6 and 12, patients were evaluated with DN4 questionnaire and the visual analog scale (VAS) for severity of sensory symptoms including paresthesia and numbness and the results were compared and analyzed. In each serial visit, possible drug side effects were asked from patients and recorded.
ResultsNeurotec reduced the feeling of coldness, pain, paresthesia and numbness VAS and DN4 scores (P of 0.01,0.05, 0.05, 0.05, 0.001, 0.05 respectively). Neurotec showed a significant advantage over gabapentin in reducing pain intensity and in other parameters the difference between the two groups was not significant. The only significant complication of Neurotec was dyspepsia that could be minimal in patients who receive the drug after a meal. Conversely in the gabapentin group, dizziness, drowsiness, and vertigo were significantly more common (P>0.05).
ConclusionNeurotec can be useful for sensory symptoms of diabetic neuropathy. Its effect on symptomatic therapy is comparable to gabapentin or even better for painful diabetic neuropathies. Its proposed mechanism in neuronal repair needs to be evaluated and can be a potential advantage over symptomatic therapies. Neurotic has no serious side effects.
Keywords: diabetic neuropathy, gabapentin, Neurotec, paresthesia -
مجله دانشکده پزشکی دانشگاه علوم پزشکی تهران، سال هشتاد و یکم شماره 2 (پیاپی 265، اردیبهشت 1402)، صص 161 -165زمینه و هدف
حضور ضایعات استخوانی تخریب کننده در ناحیه استخوان مندیبل و ماگزیلا در 30% بیماران مبتلا به مالتیپل میلوما مطرح شده است اما شروع ضایعات استخوانی از ناحیه فک نادر است.
معرفی بیمار:
خانم 52 ساله با شکایت از تورم دردناک ناحیه چپ صورت که اندازه آن از ماه پیش در حال بزرگ شدن بوده و از شش ماه پیش درناحیه چپ صورت حس پاراستزی داشته اند. بررسی هیستوپاتولوژی و رنگ آمیزی ایمونوهسیتوشیمی CD138 در کنار بررسی ها جامع استخوانی دیگر جهت تایید مالتیپل میلوما برای ایشان انجام شد.
نتیجه گیریبه نظر می رسد در بیمارانی که شروع علایم مالتیپل میلوم در ناحیه فک اتفاق می افتد با توجه به امکان تشخیص زودتر دیسکرازی پروگنوز بیمار امید بخش تر است. بروز ضایعات تخریب کننده استخوانی با تغییرات حسی در ناحیه فک و صورت نادر است و بررسی های دقیق رادیوگرافیک و خونی بیمار در این مرحله می تواند سبب تشخیص زودهنگام مالتیپل میلوما شود.
کلید واژگان: فک, مالتیپل میلوما, پاراستزی, پلاسموسایتوماBackgroundJawbone involvement and destructive bone lesions in the mandible and maxilla are reported in 30% of patients with multiple myeloma. In general, plasma cell neoplasia rarely occurs in the maxillofacial area, and an incidence of 2.6-3.3 per 100,000 people is reported for solitary plasmacytoma in jawbones. This study aims to present and evaluate a patient with multiple myeloma and the first symptoms in the maxillofacial area.
Case PresentationThe patient was a 52 years old woman complaining of painful swelling in the left area of the face that had enlarged during the last month. She was referred to the maxillofacial disease department of the Dental School of Mashhad, Iran in Feb 2022. The patient has had paresthesia in the left area of the face since 6 months ago. In the extra-oral examination, a 4×10 cm mass was observed in the left mandibular angle extending anteriorly toward the sublingual area. The oral mucosa was normal. According to the clinical profile, malignancy was considered a differential diagnosis. Incisional biopsy of the lesion revealed the proliferation of neoplastic plasma cells. The positive result of immunohistochemistry (IHC) staining for CD138, performed on the specimen to confirm plasmacytoma and detection of small primary lytic lesions in the skull and spine confirmed multiple myeloma. The usual symptoms of multiple myeloma, including low back pain, were not observed. The patient underwent chemotherapy under the supervision of a hematologist.
ConclusionJawbone involvement is often less mentioned as the first symptom of multiple myeloma; however, compared to the vertebral column or skull lesions, these areas are easily biopsied, providing the possibility of early detection and treatment of multiple myeloma, hence a promising disease prognosis. The concurrence of destructive bone lesions and sensory changes in the maxillofacial area is a red flag. Precise radiographic evaluation and blood tests can help early detect multiple myeloma. Awareness of general dentists about the possibility of blood dyscrasia such as multiple myeloma with such early symptoms in patients can lead to early diagnosis of patients. This report reminds inexperienced clinicians of the special importance of sensory changes in the head and neck.
Keywords: jaw, multiple myeloma, paresthesia, plasmacytoma -
Introduction
Intramedullary ependymoma (IE) is adults' most common intramedullary spinal tumor. Tumors usually extend one to eight segments in the cervical region. In this case report, we reported a patient with massive IE spanning from the fourth ventricle to the T4 segment of the spinal cord, which surgically treated with laminectomy from occiput to T4
Case PresentationA 42-year-old man who is a known case of IE with progressive upper extremities paraesthesia and gait disturbance. Four years ago he refused surgery and presented with dysphagia. The patient's MRI demonstrated an intramedullary spinal cord tumor extending from the fourth ventricle to T4.
Conclusionsmassive spinal ependymoma is a rare, benign, slow-growing tumor, and patients present symptoms years before diagnosis. Upon confirmation of the diagnosis, the tumor must be surgically removed.
Keywords: Brain Tumor, Ependymoma, Paresthesia -
Introduction
Intramedullary ependymoma (IE) is adults’ mostcommon intramedullary spinal tumor. Tumors usually extend one to eight segments in the cervical region. In this case report, wereported a patient with massive IE spanning from the fourth ventricle to the T4 segment of the spinal cord, which surgically treated with laminectomy from occiput to T4
Case PresentationA 42-year-old man who is a known case of IE with progressive upper extremities paraesthesia and gait disturbance. Four years ago he refused surgery and presented with dysphagia. The patient’s MRI demonstrated an intramedullary spinal cord tumor extending from the fourth ventricle to T4.
Conclusionsmassive spinal ependymoma is a rare, benign, slow-growing tumor, and patients present symptoms years before diagnosis. Upon confirmation of the diagnosis, the tumor must be surgically removed.
Keywords: Brain Tumor, Ependymoma, Paresthesia -
Paresthesia can result from some post-endodontic problems, including bacterial infections or mishaps which occur during the cleaning, shaping, and filling of the root canal. There are pharmacological and instrumental methods for the treatment of paresthesia; however, if presenting symptoms are suggestive of nerve injury, surgical approaches, such as intentional replantation, could be considered. In this case report study, we treated paresthesia that had occurred after endodontic treatment using intentional replantation. This case report describes the use of intentional replantation of a mandibular premolar as a successful technique to treat paresthesia involving the lower lip.
Keywords: Cone Beam Computed Tomography, Endodontic Treatment, Paresthesia, Premolar, Tooth Replantation -
Purpose
Heavy metals, such as lead can cause optic neuropathy. Optic disc neuropathy due to lead intoxication has previously been reported. We report a rare case of lead toxicity-induced optic neuropathy presenting with bilateral hemorrhagic optic disc swelling. Case Report: The patient was a 42-year-old man with a history of chronic oral opium use, who had a gradually progressing blurred vision in both eyes over 40 days, with ataxia, paresthesia, and a toxic level of serum lead. He had been treated with lead chelators for lead poisoning. His color vision was impaired in both eyes. Humphrey’s visual field test revealed double arcuate scotoma with enlargement of the blind spot. Funduscopy revealed bilateral optic disc swelling, which was confirmed on optical coherence tomography and fluorescein angiography.
ConclusionIn cases of optic disc edema, a comprehensive history should be taken to detect the cause. Further, in cases of chronic oral opium use, lead toxicity should be considered.
Keywords: Lead Poisoning, Opium Dependence, Optic Disc Edema, Paresthesia -
The mental nerve is a sensory nerve which traverses through mental foramen to innervate the lower lip, chin skin and the mandibular labial gingiva. Interestingly, it’s variant such as the accessory mental foramen (AMF) was described as an unusual finding in the recent literature. Hereby, we reported a patient who was operated to treat the mandibular bisphosphonate-related osteonecrosis of the jaw (BRONJ) lesion. Intraoperatively, an accessory mental foramen was detected posterior to the main foramen and nerve, on the right side of the mandible. This case report highlighted the necessity for proper radiological and clinical evaluation of mental foramina in order to avoid nerve injury and postoperative paresthesia. The review of the literature and the clinical findings were also discussed in this article.
Keywords: Accessory mental foramen, Paresthesia, Mandible, Bisphosphonate, Osteonecrosis, Jaw -
Background
Widespread use of dental implants in the past 15 years has resulted in an increase in complications associated with implant surgeries. The aim of the present study was to determine the frequency of lower lip paresthesia in patients receiving implant-supported mandibular overdentures.
MethodsIn this descriptive, cross-sectional study, 63 patients receiving implant-supported mandibular overdentures were evaluated. For clinical examination, the two-point discrimination test (2DP) was used before surgery and at 1-, 3- and 6-month postoperative intervals. Data was analyzed using descriptive statistical tests and chi-square test.
ResultsThe results showed frequency rates of 19%, 4.8% and 4.8% for lower lip paresthesia at 1-, 3- and 6-month postoperative intervals. At 1-month postoperative interval, female patients exhibited a significantly higher rate of paresthesia compared to male patients (P = 0.035).
ConclusionsLower lip paresthesia was highly prevalent (19%) one-month after implant surgery; however, its frequency decreased over time. After 3 months, the frequency of paresthesia decreased by about 3 quarters (4.8%) and remained constant until 6 months after surgery. During the 1-month period after surgery, female patients had a high rate of paresthesia compared to male patients.
Keywords: Dental implant, Inferior alveolar nerve, Overdenture, Paresthesia -
Introduction
Orofacial paresthesia is due to trauma to the neural structure of a particular nerve. In dentistry alterations caused by nerve damage in most cases are presented with transient symptomatology. However, it has been agreed by several authors that persistent inferior alveolar sensory aberrations for more than 6 months leave some degree of disability or are considered permanent. The objective of the present study is to report the clinical case of a young patient submitted to low-level laser therapy for the treatment of paresthesia of the inferior alveolar nerve after removal of a complex odontoma in the posterior region of the mandible.
MethodsTwenty-four hours after the surgical procedure the patient started the low-level laser therapy with the following parameters: 100 mW of potency, 140 J/cm² of energy density, 4 J of energy per application point, 40 seconds of application per point and 0.028 cm² of spot area. For this particular case, the technique of alternation of laser wavelengths was used, in the first session of which visible red of 660 nm was applied, followed by near-infrared of 808 nm and so on.
ResultsIn the first session, the score on the visual analog scale (VAS) was “3”. In the tenth and last sessions, the patient reported a VAS “9”.
ConclusionsIt seems that the early initiation of the low-level laser therapy favors a better outcome in cases like the one presented in this paper. The technique of alternation of laser wavelengths between sessions seems to have some role in the outcome possibly because of the constant stimulation of different chromophores along the treatment course. These two factors need further confirmation and validation through randomized clinical trials.
Keywords: Lasers, Low-Level Light Therapy, Paresthesia -
دررفتگی ضربه ای قدامی لگن از ناحیه ی اوبتوراتور یکی از نادرترین انواع دررفتگی در بین بزرگسالان است. در این مقاله گزارشی از مردی 30 ساله ارائه شده است که در اثر تصادف در قسمت لگن چپ خود احساس درد می کرده است. نتیجه ی عکسبرداری اشعه ی ایکس نشان داد که فرد دچار دررفتگی لگن از قسمت اوبتوراتور شده است. پالس های فمورال سمت چپ از سمت دیگر ضعیف تر بوده و در نیمه ی بالایی ران احساس گزگز داشته و همچنین قادر به باز کردن زانوی چپ خود نیز نبود. تحت بیهوشی عمومی دررفتگی جااندازی شده است. به مدت دو هفته بر روی محل مورد نظر کشش صورت گرفت. پس از یک ماه فرد قادر به باز کردن زانوی خود بوده و همچنین مجددا حس به قسمت بالایی ران بازگشت.
کلید واژگان: دررفتگی لگن, اعصاب فمورال, احساس گزگز کردنObturator type traumatic anterior hip dislocation in adult is rare of all type hip dislocation. Here we report the case of a 30 year old man brought to the emergency department after motor accident, complaining of left hip pain. The X RAY showed an obturator hip dislocation. Femoral pulse was weaker than the other side and had paresthesia in anteromedial of thigh and could not extend left knee. Dislocation was reduced under general anesthesia. Traction was applied for two weeks. After 1 month he could extend left knee ans sensation was regained in anteromedial of thigh.
Keywords: hip dislocation, Femoral nerve, paresthesia -
BackgroundNeurosensory disturbances following orthognathic surgery, especially sagittal split ramus osteotomy are quite common. Furthermore improving the injuries to the inferior alveolar nerve following ramus osteotomy is still a challenge.ObjectivesThis study aims to evaluate the influence of low-level laser therapy (LLLT) on the improvement of neurosensory disturbance following sagittal split ramus osteotomy.MethodsThis randomized, double- blinded clinical study was executed in a university-affiliated hospital, Tehran, Iran, during January 2017 and March 2018. Patients underwent sagittal split ramus osteotomy (SSRO) divided into case and control groups. Ten sessions of laser irradiation of 810 nanometers wavelength and power of 70 mW were rendered for eight minutes in the case group, while the patients in the control group were not irradiated. Thermal test, mechanoreceptor sensory tests, and satisfaction of the patients were evaluated during follow up examinations. Mapping of the affected skin area was marked to assess the healing process of the nerve damage.ResultsA total of 40 patients were included in the current study followed for a 12-month period. Statistical analysis of extracted data from the two-point discrimination test showed the significant better response of mechanoreceptors among the case group patients rather than the control ones (P value = 0.035). Marking the hyposthetic skin area in the patients that experienced laser therapy demonstrated that almost all of them manifested less sense on the vermilion area (85% in the case group versus 15% in the control group). Despite the control group patients whom on the mental foramen area significantly more paresthesia was experienced.ConclusionsIn conclusion, low-level laser therapy following sagittal split osteotomy may be helpful in faster recovery of nerve injuries and higher satisfaction of the patients.Keywords: Irradiation, Laser, Nerve, Osteotomy, Orthognathic Surgery, Paresthesia, Sagittal Split Ramus
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Background and aimNeurosensory disorders after implant insertion are one of the main concerns in implant treatments. Neurosensory disorders can be driven by different factors including the contact of the implant with the nerve, pressure of edema, hematoma, scar, or dental injections. This study aimed at investigating the distance between the implant and the inferior alveolar nerve (IAN) and its impact on neurosensory disorders.Materials and methodsIn this descriptive study, panoramic radiographs were taken from 100 patients experiencing neurosensory changes after 10 days of implantation. The patients were reassessed 4 weeks later, and the distance (mm) between the implants and the IAN was measured. Data were analyzed using descriptive statistics.ResultsAll patients experienced neurosensory changes 10 days after implantation. Four weeks after surgery, 82 patients healed: the distance between the implants and the IAN was 1-2 mm in 16 patients and 2 mm in 66 patients. In 18 patients, neurosensory changes persisted; in this group, the distance between the implants and the IAN was less than 1 mm in 11 patients, 1-2 mm in 6 patients, and more than 2 mm in 1 patient. The results indicated that the chance of healing of neurosensory changes is significantly correlated with the distance between the implant and the IAN (P<0.01). This correlation was not significant with respect to age or gender (P<0.9).ConclusionIt seems that the lesser is the distance between the implant and the IAN, the lower is the chance of healing of neurosensory changes.Keywords: Dental Implant, Inferior Alveolar Nerve, Paresthesia, Nerve Injuries, Sensation Disorder
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IntroductionMental neuropathy is a sensory neuropathy characterized by hypoesthe-sia or paresthesia of the chin and lower lip. It can be a symptom of a latent malignant disease.Case PresentationThis report presents a case of a 34-year-old woman with a history of breast cancer who complained of severe pain and numbness of the right lower lip. We reviewed numerous reliable articles (through PubMed and Google Search) in relation to mental neuropathy and its possible causes.ConclusionGiven that the reports of mental neuropathy have often been associated with malignancies, patients that complain of sensory impairment and numbness of the mental region should be examined carefully.Keywords: Breast Neoplasms, Neoplasm Metastasis, Neuropathy, Paresthesia
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BackgroundVitamin B12 plays a role in hematopoiesis, neuronal functions, the synthesis of myelin and epithelium, and the mucosal functions of the gastrointestinal system, so patients with vitamin B12 deficiency may complain of a variety of symptoms.ObjectivesThis study aimed to investigate the association between vitamin B12 levels and clinical symptoms in children and adolescents.MethodsPatients visiting the pediatric outpatient clinic for any reason between April 1 and September 30, 2014 were enrolled in the study. Patients with active infectious diseases, with chronic diseases, or who had any disease or were taking any medications causing vitamin B12 deficiency were excluded from the study. The patients complaints were recorded. Each patients serum vitamin B12, 25-OH vitamin D, folic acid, and complete blood count were measured in addition to routine tests.ResultsA total of 524 patients who were 8.3 ± 4.2 years old (2.6 months - 15.3 years), which consisted of 272 females (51.9%) and 252 (48.1%) males, met the inclusion criteria. The vitamin B12 level was less than 200 pg/mL in 166 (31.7%) of these patients and was less than 300 pg/dL in 302 (57.6%) of these patients. Vitamin B12 level was not associated with any complete blood count parameters except MCV. The patients with vitamin B12 deficiency were also 25-OH vitamin D deficient (PConclusionsWith vitamin B12 deficiency defined as a vitamin B12 levelKeywords: Adolescent, Pediatrics, Abdominal Pain, Paresthesia, Musculoskeletal Pain
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A 56-year-old woman with hands paresthesia referred to the physical medicine and rehabilitation Clinic of Imam Khomeini Hospital. Based on physical examination and electrodiagnosis, the patient had bilateral moderate carpal tunnel syndrome with greater intensity in the right side. Wrist splint and acupuncture were prescribed for the patient. 20 sessions of acupuncture were done every other day. At the end of treatment, the patients clinical symptoms and electrodiagnostic findings improved, and there was only mild carpal tunnel syndrome in her right hand. It seems that acupuncture can be an effective treatment for carpal tunnel syndrome. Considering its few complications, acupuncture can be used to treat mild to moderate carpal tunnel syndrome.Keywords: Syndrome, Carpal tunnel, Acupuncture, Paresthesia
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نشریه آنستزیولوژی و مراقبتهای ویژه ایران، سال سی و هفتم شماره 2 (پیاپی 90، تابستان 1394)، صص 132 -13خانمی 27 ساله با حاملگی 12 هفته و طبقه بندی کلاس 1ASA برای عمل جراحی سر کلاژ گردن رحم در فهرست عمل جراحی قرار داده شده بود. برای بیمار بیهوشی نخاعی انتخاب شد و با سوزن شماره 25 و تزریق 100 میلی گرم (2 میلی لیتر) لیدوکایین پنج درصد در وضعیت نشسته صورت گرفت. بعد از دو روز بیمار دچار درد کمر با انتشار به پای چپ شد. درد شدید و همراه احساس مورمور شدن (پارستزی) بود و برای یک ماه ادامه یافت و سپس به تدریج رفع گردید. معاینه عصبی و نوار عصب و عضله طبیعی بودند.کلید واژگان: بیهوشی نخاعی, لیدوکایین, درد, پارستزیA 27 year old woman with ASA class 1 and with 12 weaks pregnancy was scheduled for circlage of cervix. Spinal anesthesia was selected and induced with spinal needle No:25 and 100 mg (2ml) lidocaine 5% in sitting position .After 2 days , the patient sensed lumbar pain with radiation in her left foot. The pain was sever and coexisted with paresthesia and continued for 1 month and then suppressed slowly. Neurologic exam, EMG and NCV Were normal.Keywords: Spinal anesthesia, Lidocaine, Pain, Paresthesia
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Paresthesia is a burning or prickling sensation or partial numbness, resulting from neural injury. The symptoms can vary from mild neurosensory dysfunction to total loss of sensation in the innervated area. Only a few cases have described apical periodontitis to be the etiological factor of impaired sensation in the area innervated by the inferior alveolar and mental nerves. The aim of the present paper is to report a case of periapical lesion-induced paresthesia in the innervation area of the mental nerve, which was successfully treated with endodontic retreatment.Keywords: Apical periodontitis, endodontic therapy, inferior alveolar nerve, paresthesia
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مجله دانشکده پزشکی دانشگاه علوم پزشکی مشهد، سال پنجاه و هفتم شماره 6 (پیاپی 130، آذر 1393)، صص 793 -798مقدمهیکی از عوارض مزمن مهم دیابت گرفتاری سیستم عصبی است که به صورت دردهای سوزشی اندام تحتانی، پارستزی و بی حسی قسمت دیستال اندامها بروز می کند. نوروپاتی دیابتیک گاهی اوقات ممکن است به داروهای ضد درد و آنتی دپرسانت تری سیکلیک، یا بعضی از داروهای ضد تشنج پاسخ دهد. یکی از درمانهای جدید استفاده ازCoQ10 Plus Antiaging است.روش کاراین مطالعه به صورت pilot و آینده نگر بر بیماران دیابت نوع 2 که به مرکز تحقیقات یا درمانگاه غدد بیمارستان قائم درسال 1391- 1392 مراجعه و از علائم نوروپاتی شکایت داشتند، انجام شد. ازبیماران ابتدا فرم رضایت آگاهانه گرفته شد. سپس توسط همکار نورولوژیست معاینه عصبی شدند و سرعت هدایت عصبی در آنها بررسی شد. داروی Antiaging coQ10 plus روزانه تجویز شد. در ابتدا 32 بیمار دراین مطالعه شرکت نموده ولی 15 بیمار مطالعه را به پایان رساندند. پس از 3 ماه اندازه گیری سرعت هدایت عصبی دو باره بررسی و نتایج قبل و بعد از درمان باهم مقایسه شد. نتایج با آزمون تی بررسی شد.نتایجپانزده بیمار مورد بررسی قرار گرفتند. در4 مورد علایمNCV به صورت نوروپاتی حسی حرکتی قرینه آکسونال خفیف بود. ودر 8 نفر درگیری عصبی متوسط و 3 بیمار نوروپاتی شدید داشتند. نتایج NCV قبل و بعد از درمان با هم مقایسه شد که موید کاهش معنی دار موارد نوروپاتی شدید بعد از درمان می باشد (0/006=p).
HbA1C و قندخون ناشتا بعد از درمان به میزان معنی داری بترتیب (0/001>p) و (0/024=p) کاهش پیدا کردند. اثر این دارو بر سایر متغیر های آزمایشگاهی)میزان لیپیدهای سرم و کراتینین) معنی دار نبود.نتیجه گیریداروی AntiagingcoQ10 PLUS در کاهش علائم نوروپاتی می تواند موثر باشد وبه طور قابل ملاحظه ای سبب تسکین دردهای بیماران می شود.
کلید واژگان: پارستزی, نوروپاتی دیابتیکIntroductionOne of the important chronic complications of diabetes is the involvement of peripheral nervous system which presents with burning pain and paresthesia and numbness of distal extremities. Painful diabetic neuropathy sometimes may responds to antidepressant or anticonvulsant drugs. One of the recent advances is the using of Coenzyme COQ10.Materials And MethodsThis pilot and prospective randomized study was carried out on diabetic patients with neuropathic symptoms who referred to the clinic or endocrine research center of Ghaem Hospital in 2012-2013. The written Informed consent was obtained from each participant. Neurologic physical examination was done by one neurologist and nerve conduction velocity (NCV) was obtained. Then COQ10 was administered daily. At First 32 patients participated but only 15 cases completed the study. َAfter 3 months the neurologic physical examination and NCV repeated and the results were compared with the previous data by the same neurologist.ResultsOverall 15 cases were eligible and evaluated. NCV revealed mild symmetric sensory and motor axonal neuropathy in 4 and moderate in 8 cases, 3 patients had severe neuropathic involvement. NCV results before and after the treatment showed reduction in the number of cases with severe neuropathy which was statistically significant (p=0. 006). FBS and HbA1C significantly reduced after the treatment (P <0. 001) and (p=0. 024) respectively. The effect of COQ10 on other laboratory variables (serum lipids and creatinin) was not significant.ConclusionOur study showed that COQ10 can be effective on the relief of neuropathic symptoms and significantly reduces neuropathic pain.Keywords: Dabetic neuropathy, Paresthesia
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