جستجوی مقالات مرتبط با کلیدواژه "sciatica" در نشریات گروه "پزشکی"

Sciatica is one of the most common diseases of the peripheral nervous system and may be caused by pressure on the sciatic nerve. Due to the fact that piriformis muscle located near the sciatic nerve, piriformis muscle spasm may put pressure on the nerve and cause sciatica and consequently piriformis syndrome. The present study aims to investigate the effect of core stability exercises on pain and inflammation of patients with piriformis syndrome.

This is a randomized clinical trial. The study population consists of all patients with piriformis syndrome referred to medical centers in Arak, Iran from. Of these, 20 were purposefully selected and randomly divided into two groups of control (n=10) and exercise (n=10). The exercise group performed core stability exercises for 6 weeks, while the control group continued their normal life during this period. To examine the differences between the study groups, t-test, Chi-Square test, and McNemar’s test were used. The significance level was set at 0.05.

This study was approved by the Ethics Committee of Arak University of Medical Sciences (Code: IR.ARAKMU.REC.1400.157) and was registered by Iranian Registry of Clinical Trials (ID: IRCT20211003052662N1). Informed consent was obtained from all participants.

The Mean pain score in the control group decreased from 95.2 to 90.7 after the exercise, which was not statistically significant (P=0.562). In the exercise group, the mean pain score decreased from 91.7 to 33.4, and this decrease was statistically significant (P=0.0); Therefore, at 95% confidence interval, we can say that core stability exercises had a significant effect on the pain of patients with piriformis syndrome (P<0.05). The number of patients with inflamed nerve in the control group decreased from 10 in the pre-test phase to 8 in the post-test phase, but this decrease was not statistically significant (P=0.5). In the exercise group, it was reduced from 10 to 2, and this decrease was statistically significant (P=0.008); Therefore, we can say that core stability exercises had a significant effect on the inflammation of patients with piriformis syndrome (P<0.05).

Core stability exercises can reduce pain and inflammation in patients with piriformis syndrome. These exercises can be used in the treatment of these patients.

Sciatica is one of the most common diseases of the peripheral nervous system and may be caused by pressure on the sciatic nerve itself. Due to the fact that piriformis muscle located near the sciatic nerve, piriformis spasm imports pressure on nerve, it causes sciatica and eventually piriformis syndrome. Therefore, the aim of the present study was to investigate the effect of core stability exercises on pain and inflammation in patients with piriformis syndrome.

The statistical population of this study consisted of patients with piriformis syndrome referred to medical centers in Arak, from which 20 people were purposefully selected and randomly divided into two groups of 10 control and experimental located. The experimental group practiced core stability exercises for 6 weeks and the control group continued to lead a normal life during this period. In order to investigate the differences between the groups, T-Test, Chi-Square and McNemar's Test were used at a significance level of 0.05.

Ethical considerations: 

This study was approved by the Ethics Committee of Arak University of Medical Sciences with the ID IR.ARAKMU.REC.1400.157 and received a clinical trial code from the University of Medical Sciences of Iran with the code IRCT20211003052662N1, after approval by the Arak University Educational Council. In order to ensure the voluntary participation of the subjects, the consent form of participation in the project with the relevant provisions has been selected from them.

After implementing the exercise protocol, at the end of the sixth week, the average pain scores in the control group decreased from 95.2 in the pre-test to 90.7 in the post-test, which was not statistically significant (P=0.562), while In the experimental group, these scores decreased from 91.7 to 33.4, and this decrease is statistically significant (P=0.0); Therefore, it can be said with 95% confidence that core stability exercises have a significant effect on the pain of patients with piriformis syndrome at a significance level of 0.05. On the other hand, the number of people who had an inflamed nerve in the control group decreased from 10 people in the pre-test to 8 people in the post-test, and this decrease was not statistically significant (P=0.5), while in the experimental group, these people out of 10 people decreased to 2 people, and this decrease is statistically significant (P=0.008); Therefore, it can be said with 95% confidence that core stability exercises had a significant effect on the inflammation of patients with piriformis syndrome at a significance level of 0.05.

According to the findings of the present study and considering the conditions prevailing in the research samples, it can be concluded that core stability exercises improve pain and inflammation in patients with piriformis syndrome And considering the unique principles and characteristics of core stability exercises, their acceptance and positive effect among the subjects, it is hoped that these exercises will be used more and more in the treatment process of these patients.

The aim of this study was to perform a functional and histological study of the effect of coenzyme Q10 using allografts in a rat sciatic nerve repair model.

  45 male rats were randomly divided into three groups of 15. The first group received 10 μl of sterile normal saline buffer solution intraperitoneally for one week. Buffer was injected intraperitoneally to each rat. In the third group, the left sciatic nerve was removed and each rat received the sciatic nerve extracted from the second group and was injected intraperitoneally with the same volume of coenzyme Q10 at a dose of 200 mg / kg / day for one week. Rats underwent histological evaluation and histomorphometric studies and sciatic nerve function index at 4, 8 and 12 weeks postoperatively.

The morphometric and functional indices of the sciatic nerve in the third group were significantly different from the second group (P <0.05). These indicators were improved in the third group.

The results of this study showed that topical injection of coenzyme Q10 in the inflammatory phase after rat sciatic nerve resection accelerated the process of nerve regeneration by reducing the process of secondary damage.

Sciatic pain in association with lumbar disc herniation may require surgical intervention in the form of lumbar discectomy. Yet, the optimal time for this operation has not been specified in medical literature.

In a Cross-sectional study, 147 patients (100 men and 47 women) with radiological and clinical signs of L4-L5 or L5-S1 disc herniation were entered to our registry prior to March 2009. They were all examined, diagnosed and operated on (lumbar discectomy) in Ghaem General Hospital, Mashhad, Iran. Patients were all subsequently followed for one year. The follow-up continued in a number of 126 cases, whose satisfaction was rated via phone interview for an extra year. The patients’ assessments were implemented employing three scaling systems, both before and following lumbar discectomy, to name the Modified Oswestry Disability Index (MODI), Visual Analogue Scale (VAS) and Prolo Functional Economic Outcome Rating Scale (PORS). The former two were used for pre-operative and post-operative assessments whereas the latter was applied during the first year of follow-up. The focus of the investigation during second year was on patients’ satisfaction.

Mean age of our cases were 34±7.4 years. According to the duration of the sciatica, patients were divided into 4 groups. <3 months, 3 to <6 month, 6 to <12 months and >12 months. Statistical analysis revealed a significant difference between patients having undergone lumber discectomy with a history of sciatica for less and more than three month before the operation in terms of pre-and post-operative visual Analogue Scale (P= 0.022). However, there could be found no such disparity in other clinical scores (P= 0.63 for MODI, P= 0.85 for Prolo scale and P= 0.73 for satisfaction).

Patients with less than three months of sciatica may seem to enjoy a better clinical outcome after one year, there could be found no correlation between the duration of sciatica and the satisfaction after two years.