جستجوی مقالات مرتبط با کلیدواژه « نزدیک بینی » در نشریات گروه « پزشکی »

 Nearsightedness (Myopia) is one of the problems caused by refractive errors of the eye, which causes blurred vision when looking at distant objects. This disorder can be considered one of the most common human eye disorders and public health that can even lead to vision loss. In this study, we will examine the role of genetics in causing this disorder.

 This research is a review study and Iranian and foreign databases such as PUBMED, NCBI, etc. have been used to collect information in this research.

  Many of the genes that cause refractive errors in the eye can be grouped in one group.  The largest set of these genes plays a key role in the growth of connective tissue and the reorganization of the extracellular matrix. This set includes genes that encode matrix metalloproteinases, growth factors and growth factor receptors, and collagens.

  According to the reviewed articles and the obtained documents, Inheritance studies have shown that myopia is a common inherited disease. People with severe myopia are mostly at risk for vision loss and other eye problems.  Therefore, families with a history of myopia should undergo genetic testing to assess their likelihood of developing the disorder.

Clinical observations and previous studies have shown an inverse relationship between refractive error and anterior chamber depth. The aim of this study is to assess the relationship between the amount of myopia with anterior chamber parameters such as volume, angle, depth and the difference in these parameters between genders.

In this descriptive-analytic study, 83 refractive surgery candidates (-0.5 to -9) aged between 20-40who have undergone Oculyzer photography were investigated. Statistical analysis of data extracted from patient's files performed using spss18 and relation between variables were assessed by Pearson or Spearman correlation coefficient. T-test for comparison of variables or the nonparametric equivalent (Mann-Whitney) was used.

In this group there was no statisticaly significant correlation between anterior chamber volume(P=0.611, r =0.057), angle(P= 0.780, r=- 0.031), depth(P= 0.944, r=0.008) and refractive error. In comparison between genders, correlation between anterior chamber volume and depth mean differences was statistically significant (P<0.0005) but there was no statistical significant correlation between anterior chamber angle mean differences(P= 0.064)

This study shows that in myopic patients aged 20-40 years, there is no significant correlation between anterior chamber volume, angle, depth and amount of refractive error.

A number of papers have reported an association between diet and myopia. This study compared the nutritional intake and some simple body measurements in a group of children who were myopic to those of a group، who were not myopic.

The nutritional data for 169 subjects who developed myopia between the ages of 7 and 9 years were compared with data for 180 subjects who were not myopic. Dietary intake was assessed by a semi-quantitative 67-item food frequency questionnaire. T-test was used for data analysis.

Weight، height and BMI were 31. 6±8. 1 (mean±SD)، 132. 3±7. 5 and 17. 8±3. 2، respectively of the myopic children 54 (54%)، and of the controls، 45 (45. 5%) were overweight. Children who developed myopia had a generally higher intake of many of the food components than children who were not myopic. Differences were statistically significant for energy intake، protein، fat، and carbohydrate (p<0. 05). Myopic children consumed more sugar، fruit، rice، pasta، egg، dry fruit and snackes than did the subjects who were not myopic (p<0. 05).

Children with myopia were more obese than the control group and consumed high carbohydrate foods such as pasta، sugar and dry fruits.