The Relationship between Hemoglobin Levels in the First and Second Trimesters of Pregnancy and the Incidence of Pre-Eclampsia

Preeclampsia is one of the major causes of maternal mortality. Early detection of preeclampsia is one of the most important functions of prenatal care. The present study aimed to determine therelationship between hemoglobin levels in the first and second trimesters of pregnancy and the incidence of preeclampsia in pregnant women referred to Amiralmomenin hospital in Zabol.

This prospective cohort study on 130 pregnant women in the first and second trimesters with available sampling tests was performed. Prenatal tests were performed and recorded in Amiralmomenin hospital in Zabol. Then this people were followed up until delivery and three weeks after delivery for preeclampsia. Data by SPSS version 21 was examined. Significance level was set as 0.05.

Among the women examined in this cohort 11(8.46) patients developed preeclampsia. The result of this study showed the incidence of preeclampsia in women with hemoglobin less than 11 was no difference with preeclampsia in women with higher hemoglobin, but women with hemoglobin less than 11 in second trimester has the lowest incidence of preeclampsia. However when we used Cox regression models and survival control strategies, low hemoglobin in the first trimester reduced the risk of preeclampsia by 60% which was statistically significant (0.036). Beside using these models of survival analysis we observed that low hemoglobin in the second trimester reduced the risk of preeclampsia by 60%which was statistically significant (0.012).

High hemoglobin in the first and second trimesters of pregnancy can be a predictor of preeclampsia.