A comprehensive review of CNS and PNS manifestations of SARS-CoV-2 infection

The novel coronavirus (2019-nCoV, or COVID-19) was, for the first time, detected in Wuhan city (China) in 2019. It was subsequently spread worldwide which resulted in a viral pandemic associated with high rate of mortality. Although this virus mainly affects the pulmonary system, it has already been reported that COVID-19 could also affect the nervous system, either at the first stages of disease or during the illness progress. During COVID-19 pandemic, numerous neurological complications corresponding to Central Nervous System (CNS) disorders such as giddiness, headache, unconsciousness, encephalitis and ataxia, as well as Peripheral Nervous System (PNS) disturbances including Guillain-Barre syndrome (GBS), skeletal muscle malfunction, hyposmia, hypogeusia and muscle pain, were reported. In this regard, further researches about neurological manifestations of COVID-19 is suggested. Current review attempts to discuss various CNS and PNS manifestations of SARS-CoV-2 virosis.