Nanotechnology for Probiotic Delivery

Today, the role of probiotics has been confirmed as beneficial microorganisms that play a role in improving health, preventing, and controlling host clinical disorders. According to the World Health Organization, if probiotics are prescribed to the host in sufficient and appropriate amounts, they can be very beneficial for health. In order to transfer the effects of probiotics to the consumer, it is necessary for probiotic microorganisms to be metabolically stable, active in food products, and able to survive in most parts of the digestive tract while also providing their beneficial effects in the host intestine. One major issue in this field is the ability of probiotic cells to survive physical and chemical attacks during their journey through the digestive system to the intestine. Recent advances have focused on improving micro-scale encapsulation techniques in order to achieve high cell viability, resistance to stomach acid, temperature resistance, and longer shelf life. However, these microencapsulation approaches still face limitations and challenges in terms of clinical translation. This present study offers a brief overview of the current progress of various probiotic encapsulation methods, with a particular emphasis on modern and emerging single cell encapsulation strategies that use nanocoatings for individual probiotic cells. Furthermore, the advantages of different nanoencapsulation methods are discussed, and future developments in coated probiotics with advanced properties and health benefits are anticipated.