The study of repetitive Transcranial Magnetic stimulation (rTMS) on social functioning in patients with Major depression Disorder who drug Resistant

The aim of this study was to evaluate the effect of rTMS on social functioning in patients with major depression disorder who are drug resistant. Twelve Patients with major depression disorder in a quasi-experimental one group time-series design were treated with 30 sessions of 20-Hz rTMS over the left dorsolateral prefrontal cortex (LDLPFC). All the patients were assessed with Social Adaptation Self Evaluation (SASS) before and after rTMS and 1.5 months after treatment. The results showed a significant improvement of patients in SASS (p< 0.001) and these effects lasted 1.5 months after rTMS. rTMS can affect social functioning in patients with major depression disorder and probably these effects are associated with Hypothalamus-Pituitary-Adrenal axis.