فهرست مطالب amirashkan mahjoor

The testis is an important component of male reproductive system and is responsible for spermatogenesis The objective of the present study was to determine the prevalence of testicular pathology in rams and bucks in Fars province, south of Iran. An abattoir-based survey was conducted between winter 2018 and winter 2019 in Shiraz and Kazeroun industrial slaughterhouse. The bucks were categorized into three age groups of <2, 2–3, and <3years before slaughter using dental examination After slaughter, the whole genitalia were examined for evidence of gross pathological abnormalities. Tissue samples from testis were collected and fixed in 10% buffered formalin, processed, sectioned, and stained with hematoxylin and eosin for histopathological examination using light microscopy. Data obtained were summarized and presented as number of occurrencesand proportion of total population examined Out of 200 rams and 200 bucks examined in the incidence of testicular lesions was 39 (19.5 %) and 58 (%29) respectively. Testicular mineralization, besnoitiosis, testicular atrophy, testicular hypoplasia, cryptorchidism and orcitis accounted for incidences of 21 (10.5%), 11 (5.5%), 10 (5%), 8 (4%),6 (3%) and 2(1%) respectively in bucks. Testicular mineralization 10 (%5), testicular hypoplasia 8 (%4). testicular atrophy 13 (6.5%), cryptorchidism 7 (%3.5) and orcitis (%1) were the pathological conditions found in rams.

The purpose of this study was to determine the amount of liver lesions in slaughtered sheep in Yasuj slaughterhouse with specific reference to the prevalence rates, gross and histopathological features.

This study was conducted from winter 2018 - 2020. A total of 800 livers from 3062 slaughtered sheep identified as having one or more liver lesions were used for macroscopic and microscopic studies.

Fifteen percent of the 800 studied livers had liver lesions. In the macroscopic and microscopic study of these lesions, 39 cases (4.9%) were diagnosed with liver abscess, 28 cases of hydatid cyst (3.75%), 20 cases of fasciolosis (2.5%), fatty liver (2.5%) and 2 cases of scurvy cystosis (2.5%).

Our study shows the high rate of liver lesions, especially abscesses and parasites in sheep in Yasuj slaughterhouse and the need for more attention to the prevention and treatment of these lesions.

Bone tumors can be benign or malignant and primary or secondary in dogs. Osteosarcoma (OS) is considered the most common primary bone neoplasm in dogs, which has high metastasis ability.

A retrospective histopathological study was performed over cases submitted to veterinary hospitals and clinics in Shiraz, the capital city of Fars province, south of Iran. Surgery and necropsy files of dogs submitted to clinics between 2010 and 2021 were retrospectively studied and cases suspected to bone tumors by were separated.

A total of 872 necropsy and surgical resection specimens from dogs referred to these clinics because of musculoskeletal defects were reviewed during this period, of which, nine dogs (six male and three female dogs) corresponded to bone tumors.

All of the tumors were diagnosed as osteosarcoma. The epidemiological and pathological findings of these tumors are reported.

This study was conducted to determine the pathology of ascites syndrome in Kazeoon and Shiraz province south of Iran. One hundered broiler chickens from 10 different farms showing clinical signs of ascites syndrome were compared with normal broilers from same farms. Postmortem examination revealed presence of fluid in the abdominal cavity, enlargement of right ventricle of the heart and swelling of the liver and kidney. Histopathology revealed congestion and edema in the liver, congestion and myofibril degeneration in the heart, congestion and edema of the parenchyma accompanied with atelectasis and extensive dilatation in tertiary bronchus with cartilaginous mass and primary stages of ossification in the lung, heavy mononuclear cell infiltration in the spleen and necrosis, congestion, heavy infiltration of mononuclear cell in the intestine were the main features observed in ascetic broilers.

This study was carried out to determine type and prevalence of kidney lesions in sheep in Noorabad city, south of Iran.A total number of 500 clinically normal sheep of different age, sex and breeds referred to Noorabad abattoir were selected. After slaughter the kidneys of these sheep were inspected and renal samples were taken for histopathological study. Twenty-nine out of the studied kidneys had renal lesions including interstitial nephritis in 12 cases, Hemorrhage and hyperemia in 4 cases, Abscess in 4 cases cysts, acute tubular necrosis in 3 cases, glomerulonephritis in 2 cases, Medullary crest necrosis and Cloisonné kidney were in one case. The prevalence of renal lesions in female and male cattle didn’t had any significant difference.

Inroduction & Different studies have demonstrated the effects of cell phone induced electromagnetic field on hepatic cells. The aim of this study was to investigate the hrpatoprotective effects of silymarin on this kind of damages
Material and Seventy rats were divided in five groups. One control group and four exposure groups that were exposed to cell phone radiation 5 times a day for 30 days each time 10 minutes. At the end of the study all of the rats were sacrificed and Alanine Aminotransferase (ALT), aspartate aminotransferase (AST) and Alkaline Phosphatase (ALP), total proptein, total bilirubin and albumin were measured. Liver samples were obtained for histopathological studies
Cell phone radiation significantly (P≤005) increased levels of ALT, AST, ALP, total bilirubin and decreased levels of total protein and albumin. In groups treated with silymarin improve in biochemical factors were noted. Histopathological findings were consistent with biochemical findings
Our results suggest that silymarin has hepatoprotective effects on cell phone induced liver damaged due to free radical scavenger and antioxidant

Topiramate is an anti-epilepsy drug and its Consumption during pregnancy may induce skeletal and craniofacial malformations. The aim of this study was to evaluate the protective effect of folic acid on the reduction of topiramate- induced anomalies in Balb/c mice. In this study, 72 Balb/c timed-pregnant mice were divided into 6 experimental and 2 control groups. Experimental groups I,II and III received daily oral gavages of topiramate (50,100 and 200 mg/kg, respectively) and experimental groups IV, V and VI received similar doses of topiramate with 3 mg/kg/day folic acid supplement by gavage route. Control negative and positive groups received normal saline and folic acid, respectively. Oral gavages were done during GD6-GD15. Gavage of folic acid was done from 10 days before pregnancy to day 15th of pregnancy. Dams underwent Cesarean section on GD18 and were investigated by microscopic tools, and after determination of weight and crown- rump length, external examination was done and fetuses were stained with Alizarin red S and Alcian blue staining. The mean weight and crown-rump length of the fetuses in three experimental groups I, II and III were significantly reduced compared with control groups (P < 0.05). Orofacial deformities such as mandibular hypoplasia and open mouth were detected in experimental groups I, II and III. A significant decrease was seen in the incidence of these deformities in fetuses of groups IV, V and VI that received folic acid-topiramate co-administrations. Findings of this study showed that using topiramate during pregnancy may induce fetus malformations and consumption of folic acid can reduce topiramate- induced birth defects.

Camphor stimulates the nervous system and the circulatory system، reduces lactation، and prevents conception and embryo embedding. We investigated the effects of camphor on the pituitary-gonadal hormonal axis and concentration of steroidal hormones. The parameters investigated were concentrations of LH، FSH، estrogen، progesterone، and testosterone. Forty adult female rats at a mean weight of 180 ± 20 grams were divided into five groups. Camphor solution was prepared in olive oil at 25، 50، and 100 mg/kg doses، and 0. 2 cc injections were done intraperitoneally every day for 2 weeks. The control group received no injection. The sham group received olive oil (as solvent of camphor) and treatment groups of 1، 2، and 3 received doses of 25، 50، and 100 mg/kg. The treatment groups were sacrificed one day after the last injection، and their hearts were dissected and blood samples were obtained. The concentrations of the hormones were measured by the ELISA test، and the results were evaluated via the t-test، ANOVA، and Duncan. The results showed a significant decrease in the concentrations of testosterone and progesterone (p value < 0. 05) and a significant increase in the concentrations of LH and FSH (p value <0. 05). Camphor augmented oogenesis via effecting a rise in the concentrations of LH and FSH in our rats.

Soybean is known as a rich resource of phytoestrogens. These compounds have antioxidant, anti cancerous and estrogenic effects. This research was performed to evaluate the effect of hydro alcoholic extract of soybean on ovarian tissue from histopathologic and stereologiclogic aspects. Maretials and 40 adult Spraque-Dawley female rats with age range about 10 weeks and randomly divided into five groups including control, sham and experiments 1, 2 and 3. The animals of experimental groups received soybean hydro alcoholic extract at doses of 30, 60, and 120 mg/kg for 25 days respectively in oral form. The sham group received distilled water. After anesthetizing, right ovaries were been dissected and weighted, afterthat processing of tissues was done based on histological and stereological studies. Qualitative histological studies were performed by H&E and Masson’s Trichrome staining methods. In stereological studies, ovarian volume was determined by Cavalieri method. Determination of follicular percentage and corpus luteum were calculated in all groups. Our finding showed that administration of soybean extract had not significant changes percentage of preantral and graafian follicles, corpus luteum, and ovarian volume in the experimental and sham regarding to the control group. Ovary weight in the experimental group 1increased significantly. Percentage of antral follicle in experimental group 3 was elevated significantly. Atretic follicle in all experimental groups decreased significantly (p≤0.05). No histological change was showed in histopathological studies. The results showed that decrease in atretic follicle percentage and increase in antral follicle percentage is positive effects in this phenomenon. Considering beneficial effects of soybean on most body systems, it seems that its consumption in balanced doses in a diet.