mr taghavi

Diabetes is a common disorder which contributes to a variety of complications such as deficits in central auditory nervous system (CANS). Auditory late latency response (ALLR) is a well-established neurophysiological approach in the assessment of CANS performance. This study was aimed to compare ALLR in insulin dependent (Type I) diabetic patients and normal individuals.

In this descriptive analytical and non-interventional study, ALLR was measured by using tone burst 1000 Hz on 25 Type I diabetic patients and 25 age, education and sex matched healthy controls include 12 males and 13 female in both groups, with mean age 28.76±4.1 year in patients and 29.68±3.6 year in controls. Data were analyzed by t-test and Pearson correlation tests using SPSS 17 software.

The mean ALLRs latency and amplitude of the diabetic patients were significantly different when compared with that of normal controls in both genders (p<0.01). Also, there was a strong correlation between ALLR latency and HbA1c and diabetes duration (p<0.01).

Significant prolongation in latency and significant reduction in amplitude of ALLRs in the diabetic patients shows that cortical auditory information processing is slower than normal individuals.

COVID-19 is a new disease and little information is available on its risk factors. The aim of this study was to determine the mortality risk factors in patients with COVID-19 in the northeast of Iran.  
 

A case-control study was conducted. Patients of both sexes with a confirmed diagnosis of Covid-19 infection who died during the study were studied as the case group and patients who were in good general health and ready for discharge were studied as the control group. Data analysis was performed with the STATA software version 14 using descriptive statistics and univariate and multiple logistic regression tests.
 

Six hundred and eleven patients were studied (27% cases and 73% controls). Multiple logistic regression analysis showed that the odds of death were 2.8 times higher in patients over 80 years compared to patients aged 50-60 years. In addition, age under 40 years reduced the odds of mortality by 85% and living in rural areas increased odds of death by 2.2 times. Cough, general fatigue, pain, nausea and vomiting increased the odds of COVID19 survival.
 

The odds of mortality were higher in elder patients with COVID-19. In addition, living in rural areas increased the odds of mortality in patients. Cough and fatigue reduced mortality; however, it is needed to address other hidden factors for sound judgment.