جستجوی مقالات مرتبط با کلیدواژه « بافت بیضه » در نشریات گروه « زیست شناسی »

Many studies have shown the relationship between ultrasound and the function of the reproductive system. However, the mechanism of ultrasound waves action on sex hormones and testicular tissue is not perfectly clear. Accordingly, the present study investigated the effects of ultrasound waves on serum levels of DHEA-SO4, testosterone and testicular tissue in male rats.

Male wistar rats were divided into three groups: control group which was not exposed to ultrasound waves, rats that were exposed to ultrasound waves for 1h/day, and rats that were exposed to ultrasound waves for 6h/day. The serum levels of testosterone and DHEA-SO4 were measured using ELISA. The testicular tissue slides were prepared and analyzed microscopically.Data were analyzed using one-way ANOVA.

Serum levels of testosterone and DHEA-SO4 and spermatogonia, spermatocytes, sertoli cell count and seminiferous tubules morphology did not significantly changed in groups exposed to ultrasound waves compared to control animals.

Our findings show that ultrasound waves do not significantly influence male reproductive system function and histology.

Copper sulfate is one of the most important environmental pollutants that has the ability to produce free radicals and create oxidative stress. The aim of this study was to investigate the effects of copper sulfate on sperm quality parameters, DNA fragmentation rate and testicular tissue of adult Wistar rats.

In this experimental study, 30 adult Wistar rats weighing 250-200 grams were used. Random adult mice were treated in 3 control groups, copper sulfate receptor with concentration (100 mg / kg) and concentration (200 mg / kg) for 56 days. At the end of the treatment period, testicular weight, sperm count and parameters were assessed based on (WHO2010). The quality of sperm chromatin was assessed by acridine uranium nuclear pigments. Malondialdehyde level was measured. Data were analyzed using the One-Way ANOVA statistical method.

The quality of sperm parameters in copper sulfate with a concentration of 200 mg / kg decreased significantly (P <0.05). The testicular weight was significantly reduced at a dose of 200 mg / kg (P <0.05). The diameter of the seminiferous tubules, testosterone levels,, germ cell count, and sperm DNA fragmentation rate decreased at a dose of 200 mg / kg (P <0.05). The concentration of malondialdehyde at a dose of 200 mg / kg sulfate copper was significantly increased (P <0.05).

This study shows that high concentrations of copper sulfate cause destructive effects on sperm quality, testicular tissue.

Diazinon is an organophosphoric pesticide used in agricultural fields. The aim of this study was to evaluate the effect of sublethal concentrations of diazinon on testicular tissue in Danio rerio.  

For this purpose, 240 male animals with mean weight of 0.20 ± 0.05 were subjected to 0.8, 1.6 and 3.2 mg / l of diazinon and control for 30 days.

In histopathological study, the highest abnormality was observed in the highest dose (3.2 mg / l) and the most important abnormality was reduction in gonad size. In control group, the testicular tissue had adequate size and growth, and the cells were in the sexual maturity stage, but in 0.8 mg/ l, cellular atrophy and lose of lobular walls was observedIn 1.6 mg / l, the degeneration and atrophy of the sexual cells, destruction of shape and walls of the lobules was observed. At the highest concentration, the degeneration and atrophy of the sexual cells, destruction of shape and wall of the lobules and the decrease in the number of sex cells were observed. This decrease in the number of sexual cells results in reduction of testicular tissue size.

These observations indicate an increase in complications and anomalies with the increase in toxin concentrations

Inroduction & Spirulina platensis is a blue-green algae that has antioxidant and antiinflammatory compounds. In this study the effects of Spirulina platensis on spermatogenesis in male mice was investigated.
40 mice were randomly divided into 4 groups(n=10), Control: normal saline, Experimental 1: 75 mg/kg, experimental 2: 150 mg/kg and experimental 3: 300 mg/kg of Spirulina platensis received via gavage(During treatment= 30 days, every other day). After treatment the right testis of mice removed and fixed. The tissue stained with H&E. In tissues lineage cells of spermatids , epithelial thickness measured. Levels of testosterone , FSH and LH checked out. Data were analyzed with ANOVA and Duncan test. Level significant was p The number of spermatogonia , spermatocytes , epithelial thickness and level of testosterone, FSH and LH in experimental 3 increased significant compared with control group .
Spirulina platensis consumption in male mice increase the number of spermatids , FSH and testosterone.

Spermatogenesis that including complicated and precise process of cell differentiation in mammals ,begins in early adulthood and continues throughout the life of reproduction , which resulted in dividing of fundamental cells , and result of dividing meiosis ,are haploid spermatids that basically have been chenged in their testicular and epididym because of creating high performance sperm.All of stages of spermatogenesis occur simultaneously, as in pathological conditions, the smallest disruption can lead to infertility.Beginning in terms of survival and spermatogenesis by FSH and testosterone hormones are regulated. Some researchers believe that the testosteronehormone is the main hormone for regulating of spermiogenesis and FSH has a minor role. PMSG has the similar performance to FSH. in this project we will consider the effects of sex hormones PMSG and testosterone on testicular tissue and spermatogenesis. IN VITRO experiments was done in three different groups including a controlt and two experimental groups on the immature male mice that were NMRI descent and duration of tissue culture was considered 4weeks.after passing specified time and doing histology and microscopy studying, the results indicated meaningful increase in number of spermatosist, spermatid, sperm and decrease in A spermatogonia Certoli cells. These results indicate that testicular tissue culture can be a useful experimental model for studying the regulatory mechanisms of proliferation of spermatogonia.