جستجوی مقالات مرتبط با کلیدواژه « نعناع » در نشریات گروه « پزشکی »

Nitrate is an essential nutrient for the growth of plants. The presence of it in vegetables, water and other foods, is a serious threat for human health. Human body receives about 80% of nitrate from fruits and vegetables. The purpose was to determine the amount of nitrates in some vegetables and cucurbits (basil, mint, radish and tomato) that are sold in fruit and vegetable market of Zahedan city in 2020 year.

Hundred and twenty samples were selected and their nitrate content were measured by HPLCmethod. The significance level was less than 5%.

Mean of nitrate in, tomato, mint, radish and basil were 20.55, 515.76, 585.73 and 591.7mg/kg respectively. The mean of nitrate in basil was slightly higher than the radish but difference wasn’t statistically significant. There was statistically significantdifference among mean of nitrate in investigated vegetables (p value < 0.05). Mean of nitrate in basil was higher than others (p value < 0.05). A statistically significant difference was observed among mean of nitrate in vegetables namely tomato, mint, radish and basil in the investigated stalls (p value < 0.05).

Amount of nitrate in samples were lower than the national standard limit that is not harmful for human health. It can be concluded that the vegetables sold in Zahedan city are good interms of nitrate content and they don’t cause health problems. As high consumption rate of different type of vegetables by human and variation of their nitrate concentration, additional investigation and permanent control of their nitrate concentration isnecessary.

Nausea and vomiting of pregnancy is a common condition which affects the health of a pregnant woman and her fetus and significantly affects the quality of life of pregnant women. Therefore, the present study was designed aimed to compare the time effect of Mint and Lavender oil on nausea and vomiting of pregnancy based on Rhodes index.

This semi-experimental study was conducted in 2015-2016 on 107 pregnant women with a gestational age of 6-16 weeks who referred to the prenatal care clinic in Tehran. The subjects were divided into three groups: Mint, Lavender, and placebo) sesame oil). The participants respectively inhaled Mint, Lavender, and sesame oil twice a day (before rest in the afternoon and night sleep) for 20 minutes for one week. The mean total score of Rhodes index before and during the intervention days and the variables of this index before and on the seventh day after the intervention were compared in three groups. Data were analyzed by SPSS software (version 16) and statistical tests of analysis of variance, paired t, independent t, Kruskal-Wallis, Chi-square, Fisher's exact and analysis of variance with repeated measurements. P< 0.05 was considered statistically significant.

Before the intervention, there was no significant difference between the three groups in the mean total score and variables of the Rhodes index. From the fifth day after the intervention, the mean total score of the Rhodes index was significantly different between the three groups (fifth day P= 0.047, sixth day P= 0.009 and seventh day P= 0.001). The mean total score of the Rhodes index on the fifth and sixth days after the intervention was significantly lower in the Mint group than the placebo (P= 0.002 and P= 0.020, respectively). On the seventh day, the mean total score of this index was lower in the Mint and Lavender groups than the placebo group (P= 0.008 and P< 0.0001, respectively). Comparison of Rhodes index variables on the seventh day after the intervention showed that in the Mint group, the severity of nausea (P= 0.001), the frequency of nausea (P= 0.001), and the frequency of retching (P= 0.002), and in the Lavender group, the severity of nausea (P= 0.011) was less than the placebo group.

In this study, the effect of Mint aroma on pregnancy nausea and vomiting appeared earlier than Lavender aroma. Also, according to the Rhodes index, it was effective on more variables of nausea and vomiting. Mint and Lavender aroma can be considered as a simple, accessible and uncomplicated method for reducing nausea and vomiting in pregnant women.

Nowadays, water shortage crisis leads to wastewater reuse in agriculture sector. The presence of pollutants such as heavy metal in wastewater results in the accumulation of them in vegetables, and it will finally be transferred to consumers and will have irreversible effects on their health. Therefore, the present study was performed to do a systematic review along with meta-analysis on heavy metal accumulation in mint plant that is irrigated with wastewater.

Related articles were collected from databases like SID, Magiran, Iranmedex, IranDoc, Embase, Medline, PubMed, Web of Science, Scopus, and Google scholar between 1982 and 2019 and the required data were extracted. Then, due to the heterogeneity of studies entered in the research, a random effect model was applied to analyze them using STATA 14 software. Non-carcinogenic risk was assessed for children and adults.

According to the search results, 1693 articles were entered in the review process until the beginning of 2019 and finally only 12 articles were included in the research. According to the results of the meta-analysis, the order of the metals based on concentration (mg/kg) were: Zn > Ni > Cr > Cu > Pb > Cd. Also, based on the non-carcinogenic risk assessment results, mint consumption showed a significant health effects on children age group compared to adults, especially in India and Pakistan. 

wastewater reuse in agriculture sector leads to increase concentration of metals in vegetables like mint. This increased the risk of non-carcinogenicity in the age groups, especially children. Therefore, it is recommended that continuous monitoring of irrigation sources, soils, and vegetables is done to prevent the transmission of these pollutants to the human food cycle.

Nowadays, different solvents are used to extract plant antioxidants. Each solvent has a special ability to extract antioxidants materials. Accordingly, in this research, some medicinal herbs were collected from different vegetation zones of Iran and evaluated based on the majority of useful solvents. The best solvent for the extraction of antioxidants can be identified and used to determine the best herbal medicine.
 

In order to investigate the type of solvent extraction on the amount of antioxidant material of some indigenous medicinal plants of different regions of Iran such as Mentha asiatica, Ziziphora persica, Otostegia persica, Crocus sativus, Achillea millefolium, Mentha longifolia, Hyssopus officinalis, Thymus vulgaris, Fumaria officinalis and Teucrium polium, were done the experiment in The factorial based on a completely randomized design with three replications. DPPH was used to measure antioxidant activity.
 

Results showed that the extract (hydro, hydroalcoholic, acetone and methanolic) and the interaction of extract and plant on antioxidant properties had a different effect on phenol and flavonoid content (P<0.05). The highest flavonoids in the aqueous extract (87.6 mg/gDW), hydroalcoholic (147.48 mg/gDW), methanolic (277.48 mg/gDW) and acetone (171.98 mg/gDW) and also, the highest amount of phenol in aqueous extracts (15.33 mg / gDW), hydroalcoholic (20.18 mg/gDW), methanolic (51.47 mg/gDW) and acetone (31.59 mg/gDW) were found the Achillea millefolium from Ilam. The highest antioxidant activity based on DPPH test in aqueous extract (8.29% at a concentration of 16 μg/ml) belonged to the Achillea millefolium from Ilam, In hydroalcoholic extract (34.49% at a concentration of 64 μg/ml) was belonged to Mentha asiatica in Kashmar and then Achillea millefolium in Ilam, In the extract of Estonia (62.009% at a concentration of 64 μg/ml) was belonged to Mentha asiatica of Kashmar and then Teucrium polium of Kashmar and Achillea millefolium of Ilam, Finally, in the methanolic extract (95.633% at a concentration of 16 μg/ml), was belonged to the Achillea millefolium of Ilam.
 

In general, the results of this study showed that the most important solvent for the extraction of phenolic substances and the evaluation of oxidative properties was a methanol solution and the most effective plant with more substances and antioxidant activities were Achillea millefolium from Ilam region.

Chemotherapy is one of the main treatment options for cancer patients. Nausea and vomiting are also the most common side effects of chemotherapy drugs. The aim of this study was to determine the effect of aromatherapy with peppermint essential oil on nausea and vomiting in the acute phase of chemotherapy (the first 24 hours) in patients with breast cancer. This randomized clinical trial was conducted on 100 women with breast cancer who were referred to the chemotherapy centers of Imam Khomeini Hospital on an outpatient basis for the first course. Patients were randomly divided into intervention and control groups. Peppermint essential oil was used in the intervention group, while normal saline was used in the control group. Frequency and severity of acute nausea and vomiting in the first night after chemotherapy were recorded and compared using Rhodes standard questionnaire with a mean score of 0 – 32. FINDINGS: The two groups were not statistically different in terms of age, duration of cancer, history of alcohol abuse and history of nausea and vomiting. The mean score of nausea in the aromatherapy group was 1.1±1.02 and in the in the control group was 1.82±1.39 (p<0.014). The mean score of vomiting in the intervention group was 0.34±0.66 and in the control group was 0.66±0.97 (p<0.032). The results of this study showed that the use of aromatherapy with peppermint essential oil, along with the use of routine anti-nausea / vomiting drugs, can reduce nausea and vomiting in the acute phase of chemotherapy

Colonoscopy is an invasive method that is painful for patient especially for children. The aim of this research was to investigate the effect of supermint oral drop (peppermint essence) on the patients’ pain and their satisfaction after colonoscopy. In a clinical trial study, 101 patients candidate for colonoscopy were randomly divided into two groups by convenience sampling. Control group did not receive any drug. Case group received oral drop of supermint 30 minutes before colonoscopy. A standard questionnaire was filled after colonoscopy for pain and satisfaction of the patients. Data were analyzed using SPSS software and t-test. Mean value of pain, duration of colonoscopy in control group was 2.500+0.527 and in case group was 1.625+0.491 (P<0.05). 8 % in control group and 17/6% in case group had high degree of satisfaction. Mean score of satisfaction in case group was 2.607+0.566 that was significantly compared to control group (1.833+0.389) (P<0.05(. The time of colonoscopy in case group was significantly lower than the control group (P<0.05). The results of this study showed that peppermint essence causes reduce pain and increase satisfaction in patients after the colonoscopy.

Trichomonas vaginalis is a flagellate parasite causing vaginosis, a common sexual transmitted disease. Metronidazole is the drug of choice for this disease but due to its side effects, it is necessary to search for an alternative drug. In this study, the effect of Menthe piperita and Salvia officinalis on Trichomonas vaginalis was investigated. Hydro-alcoholic extracts of the two herbs were prepared. The extracts were dried using vacuum rotary evaporator. Different concentrations of the extracts in comparison with methronidazole were added in test tubes containing culture medium and the parasite. All test tubes were kept in 37ºC for 24 hours. The tubes were then expected for the parasite growth. In concentrations of 2, 2.5, 4, 5, 8, and 10 mg/ml of Salvia officinalis and in concentrations of 4, 5, 8, and 10 mg/ml of Menthe piperita the parasite did not grow. The effect of the extracts on Trichomonas vaginalis was similar to the effect of metronidazole on the parasite. Salvia officinalis and Menthe piperita had efficient effect against Trichomonas vaginalis growth in culture medium and s,o these two herbs can be considered as alternatives drugs. However, more investigation is recommended.

Pain during colonoscopy، especially in children، including the challenges faced by the medical team. The aim of study was investigation the analgesic effect Supermint oil (peppermint oil) on pain in children during colonoscopy. In this clinical trial study، 101 children (7-14 years old) candidate colonoscopy were randomly divided into two groups، respectively. About half an hour before the colonoscopy case group (n=51) was administrated oral drops Supermint oil (peppermint oil). Patients were filled a pediatric pain questionnaire. In control group (n=50) filled a questionnaire without any administration. Data were analyzed using SPSS version 11. 5 and (T-test and Paired sample t-test، Corraletion،Man withney). The mean value of pain، duration of colonoscopy in control group (5/60+1/85) was significantly different from case group (4/20+1/70) (p<0. 05). Result showed the comparison of pain between two groups was significant، so in case group، the frequency of abdominal pain were two times at maximum، but in the control group for some patients were more than 3 times (p<0. 05). In the case group abdominal pain lasting less than 1 minute and the control group were between 1 to 3 minutes، and this difference was significant (p<0. 05). We recommend using peppermint oil as a safe، without complications and inexpensive pain medication during child colonoscopy.

Nursing is known as one of stressful occupations. Due to the high sensitivity of the nursing، any carelessness and error، has created irreparable damage to the patients، their family and country and economic burden of health care increases. This study investigated the effects of peppermint aroma on the accuracy level of nurses working in intensive care units.

In this semi experimental study، 32 nurses who were employed in critical care units were selected through convenience sampling method. They were randomly subjected to peppermint essence and water (as the placebo) as the aromatherapy process in two different days. Before and after each intervention، participants were asked to take Bonardel Test. data were analyzed by SPSS16 software and paired t-test

The mean ± SD of changes in nurse''s accuracy (before and after intervention) the use of peppermint essential oil has been 8/44 ± 4/65 and placebo 1/07 ± 1/80. Changes in accuracy in the use of peppermint oil was significantly greater than placebo (p< 0/001).

Regarding the results of nurses subjected to peppermint essence and the increase in their accuracy، it is possible to apply this essence، for improving the accuracy.

Delivery is one of the critical stressful incidents in lives of most women and its associated complications can disturb the progress of labor and exacerbate post partum problems. Chewing gum is one of the new non-pharmacological methods to reduce stress. So far no study has been conducted to investigate the effect of chewing gum on the stress of labor. To determine the effect of mint chewing gum on salivary cortisol in nulliparous women in the first stage of labor. The study was a randomized، single-blind، controlled clinical trial in which 60 nulliparous women، who admitted at the first stage of labor in Omolbanin Hospital in Mashhad in 2012، were allocated to two experimental and control groups. The experimental group was asked to chew mint gum (1 gr) for 20 minutes and then their saliva sample were taken to measure cortisol level. Data were analyzed by independent and paried t-test in 5 percent level of significance with SPSS software version 11. 5. The mean salivary cortisol levels at the first and second measurement were respectively 44/9 ± 12/7 and 41/4 ± 13/0 in experimental and also 39/3 ± 10/3 and 42/8 ± 11/0 nmol in control group. The salivary cortisol level showed a significant increase from the first to the second measurement in control group (P<0. 009)، whereas a significant decrease was seen in these two measurments in experimental group (P<0. 014). Two groups were significantly different in terms of the changes in stress levels between two measurements (P>0/001). Mint chewing gum reduces salivary cortisol level at the first stage of labor in nulliparous women، which is an evidence for reducing stress. Although careful judgment aboute the exact changes in stress level are needed both laboratory and clinical studies.

Articl Dysmenorrheal is one of the prevalent complaints of women which is caused by prostaglandin release and treated with chemical drugs. Today regarding the side effects of these drugs, scientists are increasingly moving towards using herbal drugs. The present study aimed at comparing the effect of supermint and Ibuprofen on primary dysmenorrheal. This This was a clinical trial study in which100 girl medical students in Ahvaz aging between 18-22 years old who complained of dysmenorrheal and whose pain was moderate or severe participated. A total of 50 cases were excluded from the study. Verbal multi dimensional scoring, questionnaire and check list were used for gathering data. In the first cycle no medication was given (control cycle). Then they were divided into two groups: 1) 50 cases took 400mg Ibuprofen tablets every four hours if needed and 2) 50 cases were treated by supermint orally (40 drops every four hours). They used these treatments for two cycles at the beginning of each cycle. Statistical analysis was performed using the independent sample T-test, paired T-test, Mann- Whitney and Chi- square tests. This study showed that in each group pain severity mean of primary dysmenorrheal prior to treatment was significantly decreased (p=0.0001). But the rate of pain decrease between the two groups showed no significant difference (p=0.486). Regarding the results of this study, it seems that both supermint and Ibuprofen decrease pain at the same level which seems to be due to supermint, santiprostaglandin and antispasmodic effects. Therefore, supermint can be used as a safe and effective herbal drug for primary dysmenorrheal.

Several studies have demonstrated the antinociceptive, anti-inflammatory, sedative and smooth muscle relaxant activities of the Valeriane Officinalis (VO), Satureja Hortensis (SH), and Mentha Piperita (MP). The aim of this study was to determine the effects of the aqueous or hydroalcoholic extracts from these plants on morphine withdrawal syndrome signs in mice.

112 male albino mice (25-30 g) were used. Morphine was used to produce drug dependency by Marshall method. Different doses of the aqueous extracts of VO (25, 50, 100 mg/kg) and SH (25, 50, 100, 200 mg/kg IP) and the hydroalcoholic extract of MP (50, 100, 200, 500 mg/kg IP) were injected to morphine-dependent mice 30 min before the naloxone injection (2mg/kg). Control mice received saline. The severity of the morphine withdrawal responses was estimated by recordeing the number of jumping and the amount of weight feces during 3o min after naloxone injection.

The results showed that the extracts of VO (25 mg/kg), SH (200 mg/kg), and MP (all doses) significantly (P<0.05) decreased the number of jumping. Also, the VO (50 and 100 mg/kg), SH and MP (all tested doses) significantly decreased the weight of stool

Our findings indicate that the extracts of VO, SH, and MP may diminish the morphine withdrawal syndrome signs.

Introduction & Depression is a prevalent psychiatrical disease and among the most disabling psychiatrical health problems in various societies. It has been estimated that, till the year 2020, depression will be the second prevalent disease after cardio-vascular disease and will include 15% of the human diseases. This study was carried out to determine the effect of hydroalcoholic extract of Mentha piperita (complement treatment) on patient's depression severity. This is a triple blind random clinical trial research carried out on depressed patients referred to the Shahid Mofateh Clinic of Yasouj city during 2007-2008. The patient's depression severity was evaluated by Beck questionnaire and they were divided into 5 groups as random allocation and each group consisted of 24 persons. Then, Hydroalcoholic extract of Mentha piperita was given to four groups at the rate of 10.0mg, 50.0mg, 100.0mg and 200.0mg respectively per day and the fifth group received placebo. The treatment was continued for a period of two months. After this period, again the depression rates of patients were evaluated with the help of same questionnaire and were compared with the rates before the intervention. Collected data were analyzed with the help of descriptive tests, ҳ² statistical test, one way variance analyzed and variance with repeated measurements. The results of the study indicated that the highest anti depression effect was seen in those patients who received 100.0mg and 200.0mg of the extract and the lowest rate allocated to the groups of 50.0mg, placebo group and 10.0mg respectively. Statistical analysis using repeated measurements confirmed the difference at the level of 0.1 between the mean of depression rate of the five research groups before and after intervention (p=0.078). Based on the results of the current study, spearmint juice at the rate of 100.0mg and 200.0mg can be used as supplement in treatment of depressed patients. However, more studies are needed to find out the proper dose of the extract.

The study aim was to evaluate antifungal effects of Artemisia absinthium, Eucalyptus spp, Allium cepa, Cinnamomum zelanicum, Curcuma longa, Salvia officinalis, Mentha Piperita, and Calendula officinalis mouthwashes. Standard species of Candida albicans by the PTCC number 5027 was prepared from Pathogenic and Industrial bacteria and fungi collection center of Iran. Ten wild species were also prepared from the palatal mucus or buccal mucus of patients submitted to one of the clinics in Kerman. Extracts from the plants were made using percolation method with hydro alcoholic solvent followed by evaporation of the organic solvent under vacuum and then drying in a 50 oC oven. Then 0.5 McFarland suspensions from all fungi species were prepared. These suspensions were used by both small well and tube methods. All the extracts had antifungal activity against Candida albicans. However, this property in the first four plant-extracts was more powerful than the others. According to the results of this study, the extracts of Curcuma longa, Eucalyptus spp, Artemisia absinthium, Cinnamomum zelanicum had considerable antifungal effects.

One of the essential problems of using medicinal plants which are mostly collected from the wild is their fungus and microbial infections. Nowadays, exposing the plants to Gamma radiation apparently removes the problem. But, as the plants contain outstanding amount of chemical substances, the exposition can lead to a change in the composition of the plants chemicals and therefore a change in their medicinal effects. Making poisonous, carcinogen or stimulant substances in the plants could be examples of this change. The aim of this research was evaluating effect of Gamma radiation on chemical composition of ten medicinal plants essential oils; Mentha, Coriandrum, Foeniculum, Zingiber, Cuminum, Bunium, Melissa, Thymus and Zataria. Essential oil of the species before and after Gamma radiation were obtained over Clevenger apparatus, analyzed using GC and GC/MS and identified based on RT, KI and authentic references. Results showed that within ten species, the Coriander oil was affected with the 10 & 25 KG of Gamma radiation and changed to the another components. These results of experiment can alert the world, to the threatening consequences of using Gamma radiation concerning human health.