جستجوی مقالات مرتبط با کلیدواژه « seborrheic dermatitis » در نشریات گروه « پزشکی »

Background and

Seborrheic dermatitis (SD) is a chronic skin condition that is accompanied by scaling and itching. Stress and mental rumination followed by the disease affect the quality of life. The aim of this study was to investigate the effect of seborrheic dermatitis on the quality of life and to compare it with the quality of life of healthy people.

This study was a cross-sectional study. The study sample included 60 randomly selected patients with seborrheic dermatitis who referred to Bouali and Tooba dermatology clinics in Sari during 2019-2020. Two questionnaires (DLQI and SF-36) were used to assess general quality of life in patients.

The relationship between the disease and occupation was statistically significant. There was a significant relationship between smoking and seborrheic dermatitis. We also found a significant relationship between the frequency of recurrences and quality of life. The mean of physical and social function in the healthy group was higher than its value for the patient group, but the difference was not significant.

Our study showed that age, education, occupation, and smoking are factors that contribute to seborrheic dermatitis. Moreover, the findings revealed that physical and mental health as well as quality of life were less affected in the married group compared to the single group.

Scabies is one of the most important infectious skin diseases caused by the arthropod mite Sarcoptes scabiei var Homonis. Crusted scabies is a rare form of scabies that multiplies rapidly and extensively in the skin of an infected person, usually in immunocompromised patients, and is accompanied by a severe allergic reaction. Here, we report an 85-year-old man, a resident of the village, who had been severely itchy for two months.

An 85-year-old man with severe skin symptoms was referred to the Parasitology Department of Isfahan University of Medical Sciences, Isfahan, Iran, for diagnosis of skin parasitic disease. A sample of skin lesions was prepared by scraping method and observed under microscope. Under microscopic examination, by observing the mite and its eggs, scabies was diagnosed and the diagnosis of crusted scabies was confirmed according to the clinical signs.

This form of the disease occurs in people with defective immune systems, but according to the case reported here, it seems that it can also occur in people with healthy immunity.

Seborrheic dermatitis is one of the most common inflammatory skin diseases that affect the sebaceous glands. Although the exact role of vitamin D in this disease is still not clearly understood, some studies have shown lower serum levels of vitamin D in seborrheic dermatitis patients. This study aimed to investigate the correlation between vitamin D deficiency and seborrheic dermatitis.

This cross-sectional case-control study was conducted in Sina Hospital, Hamadan, Iran. The study sample included 39 seborrheic dermatitis patients (case group) and 39 healthy individuals (control group) who were matched in terms of gender and age. The groups were then compared regarding serum vitamin D level. Statistical analysis was performed in SPSS software (version 16.0; SPSS Inc.Chicago, IL).

There were no significant differences between the two groups in terms of age, gender, educational level, place of residence, and occupational status. The mean serum levels of vitamin D in the case and control groups were 11.82±5.56 and 21.38±6.79ng/ml, respectively (P=0.001). Furthermore, in the case and control groups, 18 (46.2%) and 1 (2.6%) individuals had vitamin D deficiency; 20 (51.3%) and 34 (87.2%) cases had inadequate vitamin D levels; and 1(2.6%) and 4 (10.3%) subjects had adequate levels of vitamin D, respectively. Therefore, the serum level of vitamin D was significantly lower in the case group, compared to the control group (P=0.001). Moreover, the serum level of vitamin D did not correlate with the duration and severity of seborrheic dermatitis disease (P>0.05).

According to the findings of this study, patients with seborrheic dermatitis had lower serum vitamin D levels, compared to the general population, which may be related to the pathogenicity of the disease.

Seborrheic dermatitis is a chronic inflammatory skin disease. Inflammation is one of the components of metabolic syndrome and many inflammatory cytokines play a critical role in this disease. The aim of this study was to investigate correlation between seborrheic dermatitis and metabolic syndrome.

In this case- control study 39 seborrheic dermatitis patients who referred to Sina Hospital of Hamadan as case group and 39 age and sex matched healthy individuals as control group were compared in terms of metabolic syndrome. Statistical analysis was performed using version 16.0 (SPSS Inc. Chicago, IL).

High-density lipoprotein (HDL) levels in the patient group were statistically significantly lower than in the controls (in women P=0.046 and in men P=0.044). Mean of triglyceride, cholesterol, low-density lipoprotein(LDL), fasting blood glucose (FBS), systolic and diastolic blood pressure and waist circumference in case group were more than in control group but just systolic blood pressure and waist circumference were statistically significant (P<0.05). In case group 20.5% and in control group 7.7% were afflicted metabolic syndrome which was not statistically significant (P=0.104).

Some significant parameters of metabolic syndrome in seborrheic dermatitis patients may be a predictive factor for screening.

Seborrheic dermatitis is a common inflammatory skin disease characterized by erythema, scaling, and pruritus. Antifungals are among the most commonly prescribed drugs for the treatment of this disease. In this regard, the present study investigated the efficacy of two medications including clotrimazole 1% and sertaconazole 2% in the treatment of adult seborrheic dermatitis.

This double-blinded randomized clinical trial was performed on 100 patients over the age of 18 with seborrheic dermatitis referring to Farshchian hospital, Hamadan, Iran. Patients were randomly assigned to two groups. The participants in one group received sertaconazole twice a day for four weeks and another group received clotrimazole within this period of time. After two weeks, the patients were examined in terms of clinical symptoms and side effects of medications. Moreover, they were reexamined for recurrence of disease after the completion of treatment and four weeks later. Furthermore, the level of patients' satisfaction was evaluated four weeks after treatment.

Mean and standard deviation of Scoring Index 7.16±2.20 and 6.45±2.10 before treatment (P=0.184), 4.08 ± 1.82 and 2.78 ± 2.14 two weeks after treatment (P<0.001), and 2.62 ± 2.13 and 0.89 ± 1.09 four weeks after the end of treatment (P<0.001). Additionally, the relapse rate in clotrimazole and sertaconazole groups was found to be 32% and 21.7%, respectively. Furthermore, the complication rate was reported as 8% and 8.5% in clotrimazole group and sertaconazole group, respectively (P=0.220). Moreover, the rate of good satisfaction in clotrimazole and sertaconazole groups was reported as 38% and 71.1% (P<0.001), respectively.

Based on the results of the study, the frequency of complications and recurrence of disease in patients treated with sertaconazole was comparable to treatment with clotrimazole. However, sertoconazole was found to be more effective and bring more satisfaction to patients.

Seborrhoic dermatitis is one of the most common diseases in dermatology with a prevalence of about 2%. Many treatments have been used for this disease. This Study aimed to investigate the efficacy of betamethasone lotion compared with clotrizone lotion in patients with seborrheic dermatitis of face and scalp.

This double blind study was performed on 60 patients with  seborrheic dermatitis older than 18 years, who refered to Emam Reza hospital, Mashhad. Patients were divided into two groups: clotrizone (31) and betamethasone group (29 patients). Patients were treated for a month. We evaluated severity of pruritus, erythema and desquamation of the face and scalp.

The average age of patients participating in the study was 33.1 years (18 to 56 years) and 56.7% of patients were male. No significant differences were found in age and gender between the two groups (P> 0.05). Both treatments reduced severity of erythema and desquamation of the face and scalp (P<0.001). Two weeks after treatment, clotrizone had better performance, but there after both lotions had similar effect. Betamethasone reduced pruritus more than clotrizone.

This study showed that both  betamethasone and clotrizone  were effective. Clotrizone has better impact on the severity of erythema and scaling and betamethasone has better effect on improving the severity of pruritus.

Seborrheic dermatitis (SD) is a chronic dermatitis with 1-3% prevalence and even with 33-83% in immunocompromised patients. Often, because of some of predisposing factors, abnormal proliferation of Malassezia yeasts (as a normal flora) is seen in patients that lead to observation of clinical symptoms in their bodies. The aim of this study was to evaluate of Malassezia yeasts colonization rate in patients with seborrheic dermatitis that has key importance to appropriate treatment.
This descriptive cross-sectional study was carried out during one-year period from January 2015 to February 2016 on 45 patients. According to the sample size formula, after visiting by a dermatologist and refer to the Medical Mycology Laboratory, Tehran University of Medical Sciences, patients were subjected to mycological examinations schedules. After recording the clinical symptoms and their specifications, sampling from all patients’ lesions was performed with sterile scalpel and a piece of scotch tape. Direct smears were prepared with 10% potassium hydroxide as a fungal clearing solution (KOH) and stained with methylene blue. The presence and rate of Malassezia yeast colonization was determined according to the standard procedures by direct microscopic examination.
From a total of 45 under studied patients, 66.7% had moderate to severe colonization of Malassezia yeast. In existence of sweating and stress factors, severe colonization with significant differences was seen (P In most of patients, yeast colonization rate was more than mild status, that emphasize on the etiological role of Malassezia yeasts at least as exacerbating factor in seborrheic dermatitis. On the other hand, the role of factors such as sweating and stress in inducing of severe colonization and invasive form of Malassezia yeasts in SD was confirmed, that should be considered to be treated as well as SD in therapeutic procedure.

Dandruff and seborrheic dermatitis (SD) are common chronic skin diseases. There are many chemical drugs for treating dandruff and SD. Prolonged use of them may cause side effects and drug resistance. The aim of this study was to compare the efficacy of a herbal extract lotion with clotrimazole 1% lotion in the treatment of SD.
Twenty volunteers (12 men and 8 women) aged 20 to 40 years, with seborrheic dermatitis were enrolled in this trial and were randomly allocated into two groups. One group was treated with a herbal extract lotion and the other group with clotrimazole lotion. The herbal extract contained common sage, thyme vulgaris, tea tree oil, lavender, willow, rosemary, and aloe vera. The patients were instructed to use the lotions three times a week for 4 weeks. We evaluated the patients by clinical assessment and measured the scalp sebum, pH, and dandruff number before two weeks, and four weeks after completed a treatment. At the end of the study, each participant satisfaction form.
At the end of the study, the participants whom received the herbal extract lotion had a significantly greater reduction in scalp scaling, erythema, itching, and number of dandruff compared with those who received clotrimazole (P This study showed that herbal extracts lotion was effective in the treatment of dandruff and seborrheic dermatitiand can be an appropriate alternative to chemical agents.

Background and Dandruff is a chronic illness which most people suffer from during their life time. Unfortunately there is not a definite treatment to eradicate the problem and classical medicine recommends periodical treatments to control it. Therefore, in this review study, causes of the illness and singular medications, recommended by traditional and conventional medicine have been gathered.
Material and the research was conducted in library method. 10 authoritative texts of Iranian traditional medicine and the application of “Noor” source and new scientific references and 5 new articles related to scalp, were selected and investigated and reported.
There are around 40 different singular medications among which 25 have been recommended in all documents. By clinical trial we hope to obtain better treatments for the illness.

Malassezia species (previously Pityrosporum) are normal flora of human and warm-blooded animals skin. The genus Malassezia is now divided into 13 species. Most of the yeasts show an absolute requirement for long fatty acid chains and specific procedures are required for their isolation, conservation and identification. Under appropriate conditions, the fungi can cause various skin diseases. The aims of this review were to describe recent classification of genus Malassezia; their virulence factors, and their association to dermatlogical diseases.

Malassezia that is a part of normal flora is lipophilic yeast involved in a variety of skin diseases such as seborrheic dermatitis, pityriasis versicolor, atopic dermatitis and psoriasis. Seborrheic dermatitis affects most often the sebaceous-gland-rich areas of skin such as face, scalp, and parts of the upper trunk. Dandruff is a mild variant of seborrheic dermatitis characterized by scaling. In this study, Malassezia species causing dandruff were identified.

In this descriptive study, the samples (n= 60) from participants with dandruff were examined under a microscope using 10% KOH solution and cultured in Leeming and Notman ager medium. DNA Extraction was performed from colonies by glass bead and the Malassezia genus, and species were detected by CfoI enzyme using PCR-RFLP method

Of 60, 40 (66.6%) were positive for Malassezia yeast. The positive samples in direct examination grew in culture medium. Malassezia species isolated were Malassezia globosa (25 cases), Malassezia restricta (10 cases), Malassezia furfur (3 cases) and Malassezia sympodialis (2 cases).

In most studies, the Malassezia species were identified as the agents causing seborrheic dermatitis. In our study, Malassezia globosa was isolated as a dominant species.