جستجوی مقالات مرتبط با کلیدواژه « نیتریک اکساید » در نشریات گروه « تربیت بدنی »

The purpose of the study was to investigate the acute effects of blood flow restriction (BFR), static (SS) and dynamic (DS) stretching during rest between sets of a resistance session on serum levels of growth hormone (GH), lactic acid (LA), and nitric oxide (NO) levels in men.

Twenty-eight healthy men with at least one year of regular resistance training (age: 22.28±1 years, BMI: 23.72±1 kg/m2, and fat percentage: 13.15±0.6%) participated in this study voluntarily and were randomly divided into 4 groups: blood flow restriction (BFR,30% 1RM) Static-Stretching (SS, 75% 1RM), Dynamic-Stretching (DS, 75% 1RM) and traditional resistance exercise (TRE, 75% 1RM). Resistance exercise (unilateral front knee extension on the machine) included 1 set of 30 repetition plus 3 sets of 15 repetitions for BFR and 4 sets of 15 repetitions for other groups. For BFR and other groups respectively 90 sec and 60 sec rest intervals implemented. The SS and DS groups performed static stretching on the same leg immediately after each set for 60 seconds. Serum levels of growth hormone, lactate, and nitric oxide were measured before and immediately after exercise sessions.

All four types of activities significantly increased GH, LA, and NO immediately after exercise (P=0.001). But no significant differences were observed between conditions.

Based on the findings, it can be concluded that incorporating different stretching methods (SS or DS) or utilizing BFR during rest intervals, at least for one exercise in a unilateral condition, does not provide any additional benefits compared to inactive rest intervals in the traditional resistance exercise method.

Chronic inflammation as an integral part of cardiovascular disease is associated with endothelial dysfunction. The aim of this study was to evaluate the effect of pre-intensive aerobic workout caffeine-beetroot supplementation on indicators related to vascular function including endothelial selectin (E-SELECTIN), growth differentiation factor-15 (GDF-15) and tumor necrosis factor-alpha (TNF-α) in elite  endurance runners.

In this experimental study, 10 elite male runners (age: 27.5±3.8 y, height: 176.7±7.8 cm, BMI: 22.3±1.5 kg/m2 and VO2max 52.2±4.6 ml/kg/min, were selected and with a double-blind, counterbalance, crossover and randomized design, were participated into three short-term conditions with 2 week washout. 1: high dose (9.6 mmol nitrate and 400 mg caffeine), 2: low dose (4.8 and 200) and 3: placebo. Subjects consumed 250cc of the supplement twice daily. Aerobic exercise included 5-km high intensity indoor running.

intervention, conditions and time effects with MANOVA repeated measures and bonferroni statistical analysis tests showed that the short term beetroot-caffeine supplementation (intervention effect) had no significant effect on E-SELECTIN and GDF-15, but decreased TNF-α (p=0.038). Also, that increased the GDF-15 (p=0.024), TNF-α (p=0.0001) and E-SELECTIN (p=0.047) and the supplementation after seven days (time effect) decreased the levels of TNF-α (p=0.033), GDF-15 (p=0.021) and E-SELECTIN (p=0.004) following exercise. 

an increase in the variables after exercise and decrease after seven days of the supplementation, indicates that may improves cardiac dysfunction caused by intensive aerobic exercise.

Endothelial dysfunction is the fastest symptom of vascular dysfunction in obese individuals also the onset of pre-hypertension development and along with lipid profiles can lead to dangerous cardiovascular diseases. The aim of this study was to investigate the effects of eight weeks circuit resistance training (CRT) on some endothelial markers, blood pressure and lipid profiles in pre-hypertensive obese women.

For this purpose, 24 pre-hypertensive obese women (age 44.73 ± 4.43 years, body max index 32.39 ± 3.8kg/m2, systolic blood pressure 13.21 ± 0.61 and diastolic 8.65 ± 0.33 mmHg) were randomly assigned to CRT and Control groups. CRT group performed circuit resistance training for eight weeks, three sessions per week and each session was 50 to 60 minutes. Resistance movements performs in the form of three circles and nine stations, including four upper body movements (chest press, lateral pull down, seated cable row, biceps cable curl) and three lower body movements (leg press, seated leg extension, leg curl), and two core-body movements (crunch and back extension) with 12-15 repetitions, which according to the recommendations of the American Heart Association was 40% 1RM for upper body and 60% 1RM for lower body movements. Control group didn’t have any training activities during the intervention. Blood pressure, anthropometric measurements and blood samples were collected 48 hours before the intervention and 48 hours after the last training session.

The results showed that eight weeks of circuit resistance training can significantly reduce body fat percentage (P = 0.005), waist to hip ratio (P = 0.043), systolic (P = 0.001) and diastolic (P = 0.002) blood pressure and triglycerides (P = 0.043) and significantly increase nitric oxide levels (P= 0.008).

It seems that eight weeks of CRT can decrease blood pressure by decline some lipid profile and also increase in nitric oxide levels by increase in capillary network in active muscles, and vascular flexibility.

Migraine as a one of the most common types of high frequency headaches has a significant impact on people's living conditions. The purpose of this study was to investigate the effect of 8-weeks of yoga exercises on migraine headache induces serum levels of serotonin and nitric oxide in women with migraine.

In this quasi-experimental study, 30 female (age: 36±3.2 years) with migraine were randomly divided into experimental (n=15) and control groups (n=15). The experimental group performed yoga training for 8 weeks (5 days/60 min session). Indicators included frequency of headache, duration of migraine, pain intensity (by questionnaire) and quality of life (HIT-6) were measured at pretest and posttest and blood samples were taken 48 hours before and 4 days after the last secession of exercise program in fasting state. The ANCOVA test used to examine changes in between groups.

Yoga exercise significantly reduced headache severity (P=0.002), number of headaches (P=0.006), headache duration (P=0.041) and increased quality of life (P=0.001) and nitric oxide levels in the experimental group compared to the control group significantly, but there was no significant change in serotonin levels (P≥0.05).

Eight weeks Vinyasa yoga exercises as a complementary method of life style appear to have a positive effect on improving migraine symptoms and enhancing quality of life in people with migraine.

Vascular endothelial cells play an important role in regulating vascular activity by producing vascular active substances such as endothelin-1 and nitric oxide. The aim of the present study was to evaluate the response of plasma endothelin and nitric oxide to a session of aerobic exercise with restricted blood flow in active girls. A quasi-experimental trial study was conducted as pretest and posttest. The statistical population consisted of healthy and active young women in Islamshahr, aged between 20 and 25. The sample consisted of 16 healthy and active girls who were divided into two groups of aerobic exercise with and without blood flow restriction. The blood flow restriction group with a cuff and 100 mmHg pressure and the other group with no cuffs performed the activity with the speed of 5-7 km / h on a treadmill with 60% maximal heart rate. Blood samples were collected 15 minutes and 2 hours after the activity ended. Independent t test results showed that plasma endothelin-1 concentration significantly increased in no blood flow restriction group; this increase was significantly different from the blood flow restriction group (P=0.0001). The results of independent t test showed that nitric oxide concentration was significantly higher in blood flow restriction group than the other group (P=0.0001). Aerobic exercise with blood flow restriction improves vascular endothelial function by increasing the nitric oxide secretion and possibly decreasing the function of endothelial-1 receptors.

Citrulline malate (CM) is an increasingly common dietary supplement that is thought to enhance exercise performance by increasing nitric oxide production. The aim of this study was to investigate the effect of short term use of CM supplement on NO, blood lactate, sport performance, LDH and CK in 8 healthy trained men. In a semi-experimental study, a group of 8 people randomly selected, and after attending in the first session to measure anthropometry characteristics and basic performance factors, participated in three sessions of placebo (8g dexterose) and then three sessions of supplement (8g CM). placebo or supplement was taken 60 minute before intervention sessions. Blood samples were taken in three phase, before the 4th session and after 2nd and 3rd sessions. Exercise performance factors were measured by pushup, cooper and rast tests. At the end, data were analyzed by repeated measure test as well as the follow-up Bonfroni test, at a significance level of 0/05. Results showed that acute CM supplementation compared to placebo, significantly reduced CK response to exercise (ϼ=0/041), increased NO response to exercise (ϼ=0/006), increased average anaerobic power (ϼ=0/037) and increased muscular endurance (ϼ=0/005). nevertheless, acute CM supplementation compared to placebo, didn't have a significant effect on LDH and lactate response to exercise (ϼ=1), maximal anaerobic power (ϼ=0/13) and aerobic endurance (ϼ=0/08). Acute CM supplementation may improve anaerobic performance, muscle performance, vasodilation and decrease muscle damage.

Blood pressure is affected by various factors including activity. The aim of this study was to investigate the effect of eight weeks of aerobic training on blood pressure, nitric oxide and apelin in women with pre-hypertension.

Twenty-four women aged 30-45 years with pre-hypertension were randomly divided in two groups: aerobic and control. Aerobic exercise was performed three times a week for eight weeks, This means that subjects the first week for 30 minutes at 50% heart rate reserve, the second and third weeks respectively were 35 and 40 minutes with a 50% intensity, Fourth week 40 minutes and intensity 55%, and 5th, 6th, 7th and 8th weeks run For a period 45 minutes with 55% heart rate reserve. Blood pressure measurement and blood sampling were performed one day before the first and 48 hours after the last exercise. Apelin and nitric oxide levels were measured using commercial kits by ELISA method. Statistical analysis of data was performed using independent and dependent t-test at a significant level (p <0.05).

After 8 weeks of aerobic activity, the levels of apelin and nitric oxide increased significantly in the training group (p <0.05). If the blood pressure level decreased significantly (p <0.05).

8 weeks of aerobic training can be beneficial for people with pre- hypertension by increasing nitric oxide and apelin levels and lowering blood pressure.