جستجوی مقالات مرتبط با کلیدواژه "تزریق" در نشریات گروه "پزشکی"

 Insulin injection training will lead to improved glucose control and greater satisfaction with treatment. The purpose of this study was to determine the impact of insulin injection re-education on injection errors and blood glucose control in the patients with type 2 diabetes.

This semi-experimental study was performed on 108 patients with type 2 diabetes referred to Yazd Diabetes Center using simple random sampling. The data collection tool was a researcher-made questionnaire that was completed for the patients before and three months after the intervention. The educational content was sent to the participants in the form of a five-minute video and via mobile phone. Data were analyzed using Pair t-test in SPSS 16.

The mean age of the participants was 61.44 ±8.94 years. The appropriate injection before and after the intervention in terms of the frequency of reused needle (20.4% vs 39.7% , p=0.013), keep pressing (47.2% vs 70.5%, p=0.001), size of the injection area (52.8% vs 75.3%, p=0.001), injection rotation (28.7% vs 37.2%, p=0.02 ) and insulin injection time (65.7%% vs 75.6%, p=0.04), showed a significant increase.

Insulin injection re-education can lead to reducing patients' errors related to the injection. Therefore, teaching patients at regular intervals can improve their performance in the field of insulin injection and improve the quality of treatment.

To reduce the pain caused by propofol injection, a wide range of medicinal and non-pharmacological methods have been investigated.

This double-blind randomized clinical trial study was conducted on 60 patients who were candidates for elective surgery referred to Peymaniyeh Hospital in Jahrom city. Patients were divided into two groups A: lidocaine 2% at a dose of 1 mg/kg and group B: ephedrine at a dose of 70 micrograms/kg using a random number table. Lidocaine and ephedrine were injected within 5 seconds, and after 30 seconds, propofol 1% in the amount of 3 ml (equivalent to 30 mg) was injected into the corresponding vein at a rate of 0.5 ml per second. After the injection, the patient was clearly asked about pain or discomfort at the injection site, and the answer was yes or no, and if there was pain, its severity was recorded in the questionnaire based on verbal descriptions.

Comparing the pain caused by propofol injection in the lidocaine and ephedrine groups, using the chi-square test, showed that the frequency of pain in the ephedrine group (33.3%) was not significant compared to the lidocaine group (16.7%). (p=0.20).

In the present study, both ephedrine and lidocaine drugs significantly reduced the pain caused by propofol injection, but the scale of this difference between the two groups was not significant. Therefore, these two drugs can be widely used depending on the condition of the patient in reducing pain during propofol injection.

The right to public health and well-being is one of the inalienable human rights that the government is obliged to provide and its related means. Public vaccination is one of the important tools of this right. Vaccination is mandatory in certain circumstances along with the determination of criminal and civil executive guarantees. In the research, we will investigate the legal possibility of forcing people to inject (coronavirus) vaccine in Iran's legal system.

This research is of theoretical type and the research method is descriptive-analytical and the method of data collection is library and has been done by referring to documents, books and articles.

Ethical Considerations:

 In order to organize this research, while observing the authenticity of the texts, honesty and fidelity have been observed.

Mandatory vaccination has a long history and has been observed throughout history in different societies during epidemics. With the emergence of the corona virus in the world and the need to end this dangerous epidemic, various countries of the world, including Iran's legal system, have moved towards the implementation of "compulsory vaccination" mechanisms.

Iran's legal system, in the form of a headquarters called the National Headquarters for Fighting Corona, is responsible for approving and communicating various regulations, including the requirement to inject vaccines. In the meantime, many supporters and opponents have discussed the possibility of this requirement. Opponents of this resolution have cited the powers of the National Headquarters to deal with Corona, the right to freedom, privacy and respect for sovereignty and rejection of compulsory vaccination. Proponents of this issue also point to the principle of welfare and benefit, collective interests, the principle of harmlessness and legal patriarchy, which is also considered the basis of criminalization.

Introduction:

Patient safety is an important health strategy. Therefore, it is important for nurses to safely inject principles. The purpose of this article is to provide a comprehensive overview of the researches done on the status of nurses’ performance regarding safe injection in Iran.

Materials & Methods:

This is a comprehensive review study. In order to find relevant studies, a search was conducted through Academic Jihad Scientific Database, Iranian Medical Science Database, English databases including Google Scholar, Medline, Scopus, Elsevier, PubMed, Science Direct Nurses ‘Performance and Safe Injection and Nurses’ Performance and Safety Injection were used without time limits.

Results:

Of the 56 papers obtained after a thorough review, 12 articles were selected. By studying these articles, it was found that unsafe injection methods, including preparation of contaminated medicines, contaminated needle contact, reuse of contaminated needles and syringes, improper disposal of sharp and window waste as an effective factor in transmitting diseases. Blood-borne diseases (hepatitis B, hepatitis C and AIDS) have been introduced. In most articles, the most dangerous unsafe injection that puts nurses at risk is contact with the infected needle head.

Discussion and Conclusion:

Overall, the results showed that there is no accurate and reliable information about the performance of nurses in safe injections in Iranian hospitals. Although most injections are in a relatively safe and safe range, they are expected to be fully complied with WHO guidelines that regard compliance with more than 90% of these standards. It is therefore recommended to consider supportive measures such as improving injection methods, modifying the work plan, planning training programs for the use of personal protective equipment and providing sufficient safety equipment for nurses.

The number of patients suffering from diabetic ulcers has been increased in recent years and the current therapies have faced failure. This study aimed to investigate the effects of Wharton’s jelly stem cells (WJMSCs) on the diabetic wound in an animal mode.

During this laboratory experimental study carried out in Skin and Stem Cells Research Center from March 2021 to November 2021, WJMSCs were isolated and their differentiation capability to osteocytes and adipose cells was assessed using the colorimetric method, and the expression of specific markers was evaluated using flow cytometry. 12 male Wistar rats weighing 200 to 250 grams were purchased from the Pasteur Institute and kept in the animal room in standard condition. Streptozotocin was used to induce diabetes in male Wistar rats. Animals were divided to control (normal saline injection: n=6) and WJMSCs injection (n=6) groups. Wounds with 0.8 cm in diameter were made on the back of rats. After subdermal injection of normal saline and WJMSCs, wound healing was evaluated 7, 14 and 21 days using the photography method. Data were analyzed using a t-test and analysis of variance.

The results showed that the isolation process should be performed no later than a few hours after the cesarean section. Storing the sample for one day or more caused sample contamination leading to significant failure in cell proliferation and differentiation. WJMSCs were positive for specific mesenchymal stem cell markers (CD44, D73, CD90 and CD 105, and negative for CD45 and CD 34. They were capabale to differentiate into osteocytes and adipose cells and had a high viability rate (83.1%). Subdermal injection of WJMSCs in diabetic rats resulted in acceleration of diabetic wound healing compared with the control group.

Subdermal injection of WJMSCs can effectively accelerate diabetic wound healing. According to which, applying Wharton’s jelly stem cells can be considered in cell therapy particularly in the field of diabetic wound healing.

Safe injection as a part of the quality and safe care, is one of the common methods of prescribing drugs. If safety standards are not observed, recipients and service providers may face many risks..

The present study aims to compare the effect of training through a workshop and training through an online learning content on the knowledge, attitude and practice of emergency ward nurses in selected AJA hospitals regarding safe injections.

This quasi-experimental study was performed on 46 nurses in the emergency ward of selected hospitals in Aja, Tehran in 2019-2020. Eligible participants were randomly divided into two training groups through the workshop and virtual training. The effect of training on nurses’ knowledge, attitude, and practice about safe injection before, after, and one month after the intervention was investigated. Awareness, Knowledge and attitude questionnaires and observational performance checklists were used for this purpose. Data were analyzed through descriptive and inferential tests in SPSS 23 and the significance level was considered less than 0.05.

There was no significant difference between the knowledge and attitude of the two groups before and after the intervention (P>0.05). Furthermore, there was no significant difference between the performance of the two groups before the intervention (P>0.05), but after the intervention, the performance score in the workshop training group was significantly lower than that of the other group (P<0.05). There was no significant difference between the performances of the two groups one month after the intervention (P>0.05).

The results of present study showed that the nurses who participated in the training group had a higher performance than the those trained by online learning educational content. Therefore, this method can be used to improve the performance of nurses and ultimately improve the quality of their performance in providing care services.

It is very painful and anxious for children to undergo venous and injection procedures. Exposure to severe pain and anxiety can cause mental health problems in children. There are several ways to reduce pain when injecting cocaine. In this study, we examine both pharmacological and non-pharmacological methods of reducing the severity of pain in children during injection.

In this study, a systematic review of all Iranian articles published in Persian by searching Sid, Medlib, Google scholar, Magiran and Iran Medex databases with Persian keywords; pain control, vein taking, injection and thought diversion Searched in children. Of the many articles, twenty were reviewed.

In various studies on the role of pharmacological and non-pharmacological methods such as; use of spelling cream, thought deviation (music, bubble making, touch, acupressure, musical ball, injection on doll, massage, relaxation methods, exercises Respiratory problems, etc., are among the most common methods used for painful procedures that take a short time. Therefore, interventions should be used to reduce the feeling of pain in children. , Used.

The results of studies showed that non-pharmacological methods have a greater effect on controlling children's pain during injection. Also, because non-pharmacological methods (thought deviation) are much less expensive and cost-effective than pharmaceutical methods (spelling cream), so different methods of thought deviation can be a good alternative to non-pharmaceutical methods such as spelling cream.

Pain during injection of local anesthesia causes fear and anxiety in many patients that could be a reason why patients avoid regular dental treatment. Previous studies have reported the effect of warming anesthetic solutions in various areas such as skin, plastic surgery, and cataract surgery. The purpose of this study was to evaluate the effect of warming anesthetic solution on the control of pain perception during maxillary infiltration in same patient erffering to faculty of Dentistry, Tehran Medical Sciences of Islamic Azad University at 2018.

This research was based on clinical trial,split mouth type. The patients with indication of anesthesia injection for both sides of maxilla which were agreed to participation of this study, considered as study samples.  2 percent Lidocaine (Daroopakhsh-Iran) was heated by (Tommee-Teppee-England) boiler to 40°C and the injection was performed at 37°C in the experimental group, whereas the opposite side, as the control, served 21°C (room temperature) injection. Either side of maxilla was conducted randomly as experimental group (warm injection) and control group (room temperature injection). The intensity of pain perceived during the injection was assessed by 100 mm Visual Analog Scale and statistically analyzed by the MANN-U-WHITNEY test.

Evaluation was made on 16 patients and regarding to type of study, 32 sides. Of samples, 7 male and 13 females were present and age average of them was 36.1±12.98 years old. VAS scores in the control group (room temperature injection) was 38.5±28.5 and in the experimental group (warm injection) was 27.5±20.9. Pain perception was 75% in the control group and 25% in the experimental group (P <0.01).

Warming local anesthetic solution prior to injection can efficiently reduce the pain compared to its use at room temperature.

Cardiovascular diseases (CVD) are the primary cause of death worldwide, and the development of scar tissue in myocardium and also the irreversible destruction of cardiomyocytes are the main factors in their development. There are still limitations in medical treatment of CVD, despite the advances in the field of drug therapy and surgery for CVD. In recent years, research on stem cells has led to potential application of them in in various clinical and pre-clinical trials to treat various cardiovascular diseases given the unique features of stem cells. However, the results of clinical trials have been inconsistent on human samples and have had limited therapeutic effects. To overcome these limitations, the exact diagnosis of disease, identification of stem cells, their method of injection and mechanism of action, as well as patient's individual profile are necessary to predict the response to stem cell therapy, provide the highest quality of treatment and reduce the side effects. In the present study, we have introduced different types of stem cells, their injection methods and mechanisms of action for cell therapy in CVD as well as the challenges posed in this field. Also, solutions for genetic and non-genetic manipulations are suggested to increase the survival and efficiency of stem cells. For this purpose, the articles published between 1992 and 2018 were studied using the following keywords: "stem cell", "cell therapy", "injection", "tissue engineering" and " Gene therapy".

Backgroud & Aim: This study was conducted to determine the effects of the injection rate in infiltration technique on pain, anxiety and vital signs of the patients using ICT injection device amongst the patients referring to the periodontics and oral and maxillofacial department of Azad University of Tehran in 2016. The method of the current study was randomized single blind-split mouth clinical trial. 30 patients need to be injected bilaterally on maxilla in two treatment sessions. Next, each sample was selected randomly to be injected at two paces (25 seconds or 120 seconds) Then the pain measurements were performed in Visual analogue scale (VAS), and vital signs (breathing patterns and heart rate) before, right after and 5 minutes after the injection with anxiety measurements (FAS) and digital sets of Buerer BM60 by a person unaware of the groupings. After data collection, Kolmogorov-Smirnov and t-squared tests were used to analyze the data. The pain levels were significantly different between the pace of 120 s and 25 s (p= 0.0006) as the lower pace resulted in less pain comparing to faster injections.
The hypotension was significantly different as well in 120 s and 25 s (p=0.029) Injection with slow velocity resulted in a change in the lower systolic pressure immediately after injection (128.87 ± 14.36) compared with the time before injection for the patient (130.53 ± 13.38), compared to rapid injection immediately after injection (124.97 ± 14.09) compared to the time before injection for the patient (128.00 ± 10.92). There were no significant differences in other variables (p=0.1)

In slower injection rate the pain is less than faster injection. Also slow-injection, as compared to rapid-injection, cause to less changes in systolic blood pressure immediately after injection. The injection rate did not affect the patient's heart rate, diastolic pressure, and anxiety.

Blood-injection phobia is a chronic and debilitating disorder in children and adolescents which can be associated with anxiety avoidance of many essential treatments. Although there are some current recommended treatments for blood-injection phobia, little evidence is available on the virtual reality therapy. Therefore, in this study we aimed to investigate the effect of virtual reality therapy on blood-injection phobia among children and adolescents.
In this quasi-experimental study, 31 children and adolescents aged 6 to 18 years with the diagnosis of blood-injection phobia were investigated. All children received 12 sessions of working with virtual reality software. The children's anxiety level was assessed using Spielberger and specific symptoms of blood-injection phobia questionnaires. Statistical analysis was performed using SPSS software.
Findings: After working with the software, the mean scores of state, trait, and state-trait anxiety and also blood-injection phobia in children were significantly lower than their levels before working with the software (P Virtual reality therapy can effectively reduce state, trait, and state-trait anxiety and also blood-injection phobia in children and adolescents. However, further studies are required to determine the best version of virtual reality software for blood-injection phobia.

Blood transfusion is common in infants. Due to the weakened immune system of newborns and the risk of blood transfusion complications, it is necessary to pay more attention following or after to blood transfusion. The aim of this study was to evaluate the frequency and risk factors of blood transfusions in hospitalized neonates.
A cross-sectional study was performed on 1106 infants admitted in the neonatal intensive care unit (NICU) of Mustafa Khomeini University Hospital, Tehran, Iran, from spring 2009 to 2012. Frequency and the reason for of blood components transfusion including fresh frozen plasma, platelets, whole blood, packed red blood cells, cryoprecipitate and relationship with gestational age, sex, birth weight, Apgar score, duration of hospitalization, use of mechanical ventilation were assessed. Statistical analysis was performed with SPSS statistical software, version 16 (IBM, Armonk, NY, USA) and statistical test, chi-square test, independent t-test and analysis of variance (ANOVA).
Among 1106 infants admitted to the neonatal intensive care unit, 221 infants (%19.98) received blood products. 82 of all (37%) were female and 139 (%63) were female. 113 (51%) of neonate were preterm and 108 (48%) were term. From 361 times of blood transfusions, 121 infant (54.75%) received at least one blood product. The frequency of blood transfusion was between 39 and 1 times, with an average of 3.65 times per infant. Frequency of fresh frozen plasma infusion was 173 (47.9%), packed cell 122 (33%), platelet 32 (8.8%), cryoprecipitate 20 (5.1%) and whole blood 3 unit (0.83%). The most common causes for fresh frozen plasma transfusion was replacement therapy 140 (80%), for packed cell, to correct symptomatic anemia 68 (55.6%), for platelet transfusions was to prevent bleeding in neonates with thrombocytopenia 20 (62.5%) and cryoprecipitate for bleeding caused by DIC in 18 infant (90%). There was significant relation between frequency of blood transfusions with gestational age (P=0.002), birth weight (P=0.01), cause of hospitalization (P=0.001) using of ventilator (P=0.002), and length of hospital stay (P=0.001).
With attention to the guidelines of blood transfusions and controlling factors affecting premature birth and low weight infants, reducing length of hospital stay and duration of mechanical ventilation, frequency and complications of blood transfusion can be effectively decreased.

Injection is one of the most common nursing procedures in nursing profession that requires compliance with specific standard of safety. The aim of this study is determination the effect of multi-media education program on knowledge and practice of nurses about injection safety.
Material & It was a quasi-experimental, one group (before and after) design. The census sample consisted of 50 nurses whom worked in Minoodasht, Hospital affiliated to Golestan University of Medical Sciences that had been. The tool for data gathering was knowledge questionnaire and observational practice checklist. The knowledge questionnaire completed by nurses before and six weeks after educational intervention and practice were observed using a checklist. The intervention was a two- week multimedia educational program. Data was analyzed by descriptive statistics and paired T test, using SPSS-PC (v.16).
The results showed that, the mean knowledge score, after intervention was significantly increased (P The results showed that multimedia educational program increased the knowledge and improved the practice of nurses about safe injection. As regards, the safe injection is one of the most important duties of nurses, so it is recommended that they use these strategies to enhance their clinical practice.

Injection is one of the most stressful dental procedures. The purpose of this study was to investigate the effect of video glasses in reducing anxiety and pain during inferior alveolar nerve block injection. This experimental study was performed on 40 children 6-8 years old. Children were randomly assigned to two groups. Each group was treated in three sessions. Children’s inherent anxiety was assessed in the first session and prophylaxis and fluoride therapy was performed for all children without anxiety. In the second session in the first group, injection was applied with glasses and in the second group, injection was applied without glasses. In the third session, in the first group injection was applied without glasses and in the second group, injection was applied with glasses. Visual analog scale pain assessment methods were used. Assessment of anxiety was done using the Modified Children Dental Anxiety Scale. The data were analyzed with Mann-Whitney and using SPSS 15 software. Average pain in the first group of video glasses was 1.89+_0.65 that this amount increased in the second session without glasses to 3.00±0.81. In the second group, the mean pain in the first session without glasses was 3.05±0.60 and this amount in the second session with glasses declined to 2.05±0.60. The difference between the two sessions in the two groups was statistically significant (P <0.001). Based on our findings, the use of audio-visual glasses is effective in reducing pain and anxiety during dental treatments.

The placement of dentist during injection is effective on patient’s anxiety. So this research was conducted to compare the effect of standing in front or behind the patient while administering MINB injection on patient’s anxiety at the surgery department of Dental branch of Islamic Azad University in 1392-93. In this randomized splitmouth clinical trial study, 40 adults with complete awareness of study procedure, were entered in to the study. The patient’s anxiety was determined by a 17item BISS questionnaire. The patients were allocated to the case (injection from behind) and controls (injection from the front) groups by a randomized method. The effect of operator position during injection on the anxiety of patients, was measured at the end of injections and the rate of anxiety was determined. The data was analyzed using MANN-U- WHITNEY test by SPSS version 20. The mean changes of anxiety score after injection versus patients statements before injection in group that their injection was from behind, 0.85±0.12 reduced and in the group whose injection was from the front, 0.4±0.74 increased. (P=0.007) Probably the patient’s anxiety in MINB injection, for groups whose injection was from behind, was significantly lower than patients whose injections was from front.

Injection is a usual procedures in nursing which can cause pain and this pain can lead to anxiety، discomfort and reduce the trust of the patients for the nurse’s abilities. As promoting patient''s comfort is among the nursing duty، this study was designed to compare the effect of Emla cream and cold compress on reducing the Enoxaparin injection site. This clinical trial with cross over planning study was performed on 53 inpatients at different wards of Yazd Shahid Sadughi Hospital with the order of administrating subcutaneous injection of 60mg Enoxaparine selected by convenient sampling method. EMLA cream، cold compress and control (routine intervention) were used for each case in three stages with 24 hours intervals. Site pain intensity was measured immediately after the injection by VAS and was analyzed using Fridman، Man Withney، Kruskal Wallis test by using the SPSS16 software. The mean of the severity of pain was 3/88±1/91without any interventions، 2/01±1/93 using Emla cream and 1/54±1/50 using of cold compress. There was a significant difference between the three methods (p<0/0001). Using Emla cream and cold compression reduced the pain of injection (p<0/05). But، there was not a significant differences between using these two methods on the reduction of pain. (p>0/05) According to the results of this study although using these two methods can reduce the pain in Enoxaparin injection site، as to the level of availability and cost effectiveness cold compress is suggested.

Prevention of arthrofibrosis by different drugs and surgical techniques is an essential issue in modern orthopaedics. This study investigated the effect of bevacizumab on intra-articular fibrosis in a rabbit animal model. Arthrofibrosis was induced in right stifle joint of thirty male white rabbits by removing the cortical bone of femoral condyle in medial gutter under general anesthesia. The rabbits were randomly divided into three equal groups. The control group received intra-articular injection of saline; the «one-injection» group received a single dose of bevacizumab (2. 5 mg/kg)، and the «two-injection» group received two intra-articular injections on the day of operation and 14 days later. Forty five days after the surgery، the animals were sacrificed. The severity of fibrosis was assessed by range of motion of the stifles، macroscopic adhesion score، and histopathologic variables. Although no statistical difference was seen between the control group and the «one-injection» group in terms of range of motion and macroscopic evaluation، the histopathologic variables in prevention of arthrofibrosis، except for the granulation tissue، were significantly better in the «one-injection» group. The «two-injection» group in comparison to the «one-injection» group was better not only in range of motion evaluation (p=. 001) and visual adhesion score (p=. 012)، but also in most of the histopathologic variables، except for the cell count and granulation tissue. Two injections of bevacizumab for prevention of arthrofibrosis resulted in better outcome than single injection.

Temporomandibular joint (TMJ) dysfunction is one of the most common jaw disorders. Corticosteroids are indicated for severe pain in the TMJ، related to inflammatory conditions. The aim of this study was to compare histological effects of intraperitoneal injection of dexamethasone and hydrocortisone on TMJ inflammation in rats.

In this experimental study twenty-seven rats weighing 200-250 g were used. Inflammation was induced by opening the rats’ mouth 20 mm manually once a day for 10 consecutive days. The rats were randomly divided into three groups. Group I rats (n = 3) were left without any treatment; the rats in group II (n = 12) were injected with a single intraperitoneal dose of 1. 2 mg/kg of dexamethasone; the rats in group III (n = 12) were injected 32 mg/kg of hydrocortisone after 11 days. The control rats were sacrificed at 6 weeks، while the rats in groups II and III were sacrificed at weeks 1 and 6 after injection. The groups received scores of 1-11 according to four factors of synovial hyperpelasia، vascularity، fibrin deposits and synovial adhesion. Data were analyzed with Mann-Whitney and Kruskal-Wallis tests (α = 0. 05).

The results of this study indicated statistically significant differences in inflammation severity between the experimental groups of II and III and the control group (p value = 0. 006). There was a significant difference in inflammation severity in group II between week 2 and week 6 (p value = 0. 026).

Intraperitoneal injection of dexamethasone and hydrocortisone was seen to reduce rat TMJ inflammation in the histological evaluation. The greatest inflammatory response was seen in group II six weeks after injection of medicine.

Introduction and

Infants often undergo painful procedures such as vaccination and blood sampling. Kangaroo Mother Care (KMC) and breastfeeding methods may be desirable in order to create positive interaction between mother and child. The objective of this study was to assess and compare the analgesic effect of KMC and breastfeeding methods during immunization injections in infants.

In this randomized controlled trial, 180 infants undergoing DPT vaccination were divided randomly into three groups. Breastfeeding was performed from 2 minutes before, during, and one minute after the injection in breastfeeding group, while kangaroo mother care started 10 minutes before the injection and continued for one minute after the injection in KMC group. Symptoms associated with pain were evaluated using the Neonatal Infant Pain Scale (NIPS), crying time, and latency to cry.

The mean severity of pain was 3.5±1.53, 4.38±1.37, and 5.43±0.96 in breastfeeding, KMC, and control groups, respectively, and their difference was statistically significant (p < 0.001). The mean crying times for breastfeeding, KMC, and control groups were 34.62±14.40 s, 49.87±26.57 s, and 61.17±22.08 s, respectively, which were significantly different (p < 0.001). The mean latency to cry showed no significant difference in the three groups (p = 0.927).

Both breastfeeding and KMC showed an analgesic effect in infants, but breastfeeding was more effective than KMC. Health care workers are recommended to encourage parents to use simple pain reduction methods for relieving pain, facilitating acceptance of mother, and promoting quality health care.

Using various ways to decrease drug adverse pain during labor pain is accompanied by weakening of the pulmonary system of the mature fetus, and maternal mortality. The present study aimed at evaluating injection of distilled water in decreasing back pain during the active phase of labor. In this double blind clinical trial study, 160 primigravidas -applying sequential sampling- were randomly divided into two groups; cases and controls. In the cases distilled water was subcutaneously injected in the Sacrum while normal saline was used for the controls. Then, pain degree was measured using Visual Analogue Scale (VAS) before injection and 40, 60 and 90 minutes after injection. The obtained data was analyzed by means of SPSS software (version 15); Mann Whitney, Freedman, Wilcoxon, and Chi-square tests. In both groups, mean pain intensity decreased in all of the recording time (40,60 and 90 minutes after injection), at 60 and 90 minutes to 40, and at 90 minutes to 60; which was statistically significant. Mean variation of pain intensity at 40, 60 and 90 minutes after injection was not significant in both groups. 32.4% of the cases and 27.5% of the controls demanded analgesics in order to decrease pain. Inclination to use this method again was not different in both groups. Regarding the effect of subcutaneously injection of distilled water injection on decreasing the growing intensity of pain during the active phase of labor, applying this technique is recommended.