جستجوی مقالات مرتبط با کلیدواژه « علائم بالینی » در نشریات گروه « پزشکی »

The novel coronavirus pandemic (SARS-Cov2) has presented daunting challenges to health systems in numerous countries. The levels of protective antibodies and predisposing factors are great contributors to people's susceptibility, especially in work environments. The present study aimed to assess the levels of IgM and IgG antibodies against COVID-19 and their relationships with other demographic findings in the employees of Mashhad University of Medical Sciences.

In this cross-sectional study, 758 employees of Mashhad University of Medical Sciences were selected by convenience sampling method. The data were collected using the country's standard questionnaire, and the level of IgG and IgM antibodies against SARS-CoV2 was determined by ELISA. The results were analyzed in SPSS software (version 16) using related statistical tests (P<0.05).

As evidenced by the obtained results, 386 (50.9%) cases were male, and the rest were female. IgG and IgM antibodies were found in 138 (18.9%) and 41 (5.6%) participants, respectively. The most common symptoms in subjects who experienced the disease were cough, fever, chills, headache, shortness of breath, loss of smell, weakness, myalgia, arthralgia, and impaired consciousness. The use of public transportation, history of travel, and frequent presence at work were significantly found to be predisposing factors. In the diagnostic process, radiological examination (CT-Scan), molecular test (PCR), and antibody test when symptoms appeared were requested, respectively.

During infectious epidemics, it is recommended to pay close attention to maintaining social distancing, raising awareness, frequent health monitoring, and air conditioning.

The novel coronavirus disease (COVID-19) was first reported in late November 2019. Identifying the characteristics of this disease can help make decisions and control the pandemic. The present study aims to determine the characteristics and clinical results of patients with COVID-19 hospitalized in Masih Deneshvari Hospital in Tehran, Iran.

In this cross-sectional study, the study population consists of all patients diagnosed with COVID-19 and hospitalized in Masih Deneshvari Hospital in Tehran from February to May 2020. By using a prepared checklist, the demographic and disease-related characteristics of patients were extracted,. The data were then entered into SPSS software and were analyzed using descriptive statistics and chi-square test. P<0.05 was considered statistically significant.

In this study, 700 patients were examined, of whom 451 (64.4%) were male and the rest were female. The most common symptoms were shortness of breath (97.8%) and cough (96.4%). The highest rate of infection was in the age group of 56-65 years. Also, 640 (91.4%) had underlying diseases and 42% were overweight (BMI: 25-29.9 kg/m2). Moreover, 88.2% were recovered and 11.8% were died.

Most of the people infected with COVID-19 admitted to the study hospital were male and middle-aged. Analyzing the relationship between different factors in epidemiological studies can increase the attention of caregivers and decision makers to reduce the spread of the diseases.

Due to the increase in the number of the elderly and the increasing incidence of dementia, early diagnosis of this cognitive disorder has become particularly important, because with timely diagnosis and treatment, the course of the disease can be slowed down and the quality of life of the patient and those around them can be improved. The aim of the present study was to compare the consistency and diagnostic ability of CDR (Clinical Dementia Rating) and FAB (Frontal Assessment Battery) tests with clinical symptoms contained in the Neuropsychiatric Inventory (NPI).

A cross-sectional study was performed in a hospital clinic in Tehran. Using available sampling, 60 individuals over 65 years of age were selected. First, CDR test was performed on the participants and based on the severity of dementia (mild, moderate, and severe), they were scored one to three, respectively. In this population, the test was performed based on the FAB questionnaire and, as for the score, the lower the score, the more severe the cognitive impairment. Then, 12 components of NPI were evaluated based on a questionnaire. The CDR and FAB scores were compared and the scores of each were compared with the NPI scores to determine which of the two cognitive tests was more consistent with clinical signs. The calculated reliability scales were 81% for CDR, 88% for FAB, and 86% for NPI. Data were analyzed using SPSS, version 22, and using statistical methods running chi-square test and spearman correlation coefficient.

This study included 60 patients with dementia with the mean age and standard deviation of 75.39 ± 7.25 years. Totally, 36 patients (0.60%) were female, 39 (0.65%) were literate, and 46 (76.7%) had underlying diseases. The agreement between NPI and FAB was -0.64 and the agreement between NPI and CDR was 0.68 (P <0.001), which indicates a relatively strong relationship between NPI with both tests and whatever score as the NPI increases, so does the severity of the cognitive impairment. This indicates clinical association and no significant difference between the two tests. There was a significant relationship between CDR score and education level (P = 0.004), but there was no significant relationship between CDR and FAB with gender (P = 0.284).

Both CDR and FAB tests have the same utility.

Older adults with chronic diseases are at higher risk for infectious diseases, especially COVID-19. The aim of this study was to investigate the clinical manifestations in aged people with COVID-19 in Mazandaran province between March 2020 and September 2021.

In a retrospective descriptive study, we studied demographic information, symptoms, and clinical manifestations of all patients over 60 years of age with COVID-19 admitted to medical centers affiliated with Mazandaran University of Medical Sciences. The checklist provided by the Ministry of Health and Medical Education available in the Medical Care Monitoring Center (MCMC) of the province was used.

Totally, 40804 older adults were hospitalized, including 21405 (52.36%) women. Most of the patients aged 60-75 years old (68%). In 49%, the time from the onset of symptoms to hospitalization was less than five days. Respiratory diseases (34%), heart disease and hypertension (25%), and diabetes (20.99%) were the most common underlying diseases. The main clinical symptoms were cough (26.43%), respiratory distress (26.33%), and fever (22.77%). The mortality rate was 12.08% (n= 4930).

According to this study, chronic diseases in older population worsens the symptoms of COVID-19, which is consistent with other age groups. Care and intervention measures, such as self-care education could be of great benefit in promoting the health of aged people.

Recognition of the factors influencing the severity of the COVID-19 disease is gradually evolving. This study was aimed to investigate the demographic factors associated with patients who suffered from COVID-19.

In the present cross-sectional study, 3100 patients with COVID-19 in the city of Shiraz completed an online questionnaire from December to March 2021. The sampling method in this study was simple random. The data collection tool included a researcher-made questionnaire containing demographic and clinical information of the patients, which its validity and reliability were confirmed. Descriptive analyzes were used for qualitative and quantitative data. The Chi-square test was used to examine the relationship between independent and dependent variables. The normality of quantitative variables was assessed using the Shapiro-Wilk test and statistical graphs (Histogram and box-plot).

The average age of the participants in the present study was 38.28±12.83 years. There was a significant relationship between age, marital status, level of education, job status, and history of chronic disease with hospitalization (P-Value≤0.001). There was no statistically significant relationship between gender (P-Value=0.419), smoking (P-Value=0.653), social distancing (P-Value=0.054) with hospitalization. In addition, there was also a significant relationship between age, gender, job status, and mask usage with home treatment of COVID-19 (P-Value ≤0.001).

Age, marital status, level of education, employment status, and history of chronic diseases are among the influential factors on COVID-19 disease. Identifying the factors influencing COVID-19 disease can help to prevent and control the disease.

Coronavirus disease 2019 (COVID-19) is an emerging disease, whose first case was reported in December 2019, and rapidly affected the world. Therefore, the present study was conducted to investigate the frequency and factors associated with morbidity and mortality due to COVID -19 in Ghaen, Iran.

This retrospective descriptive-analytical study used the information sources of the portal of Shohada Ghaen Hospital, Gaen, Iran, from March 2020 to December 2021, which was collected from 1,124 patients with suspected respiratory infection referring to the hospital. Data using Chi-square and Fisher's exact test for univariate relationships. Moreover, two-way logistic regression was used to investigate the causal relationships, and P<0.05 was considered statistically significant.

In this study, the mean age of participants (n=1,124) was obtained at 51.6±24.5 years, and 546 (48.6%) subjects had a positive COVID-19 test by reverse transcription polymerase chain reaction, among whom 65 (11.9%) cases passed away. Clinical symptoms of body aches, coughs, diarrhea, and shortness of breath were associated with a positive COVID-19 test. It was also revealed that habitat, diabetes, cardiovascular and lung diseases, age, and job were risk factors of COVID-19 infection, and hospitalization in the ICU and age were identified as risk factors for COVID-19-caused death (P<0.05).

In the present study, cough and shortness of breath were found to be the most frequent symptoms among patients and deceased individuals. Since these symptoms may be associated with a worse prognosis, they require the special attention of medical staff. The findings of this study also showed that the elderly were more at risk of death from this disease than other age groups, which increased the need for more education and attention to this group of society.

In December 2019, a kind of viral pneumonia associated with the 2019 novel coronavirus (2019-nCoV) appeared in Wuhan, China and then a pandemic of COVID-19 created. We aimed to clarify the epidemiological, clinical findings and imaging characteristics of COVID-19 pneumonia.

In this cross-sectional study, after reviewing the records cases of the patients who died from covid-19 referred to the Baqiyatallah hospital, as a referral center in Tehran (20 Feb 2019 to 20 May 2020). In this time, 3220 patients met clinical manifestation of COVID-19 which 278 cases were included in our study. Demographic data and clinical and imaging findings of patients were recorded. The data were entered into SPSS Ver.26 software and analyzed subsequently.

278 patients who died from COVID-19 enrolled in the study. The average age was 66.01 (SD 13.7), including 207 (74.5%) men and 71 (25.5%) women. 193 (69.4%) patients at least had an underlying disease. The most common clinical presentations include fever in 194 (69.8%), cough in 148 (53.2%) and shortness of breath in 230 (82.7%) patients. Ground-glass opacity in 243 (87.4%) of the patients was the most apparent finding in their lung CT Scan. The Mortality rate of COVID-19 in this study was 8.63%. although, there was no relationship between the pattern of CT-scan and oxygen saturation in the mentioned patients (P >0.05).

This study showed that two-thirds of the death cases were the old men who had a least an underlying disease; this requires a specific consideration on their management and follow-up; wherefore, their more prolonged admission days have a financial load on the health system.

Over the past year, COVID-19 has been identified as a major health problem worldwide. The aim of this study was to determine the demographic and clinical characteristics of patients with COVID-19 in Iranshahr hospitals, southeastern Iran in 2020.

In the present cross-sectional study, patients admitted with a definitive diagnosis of COVID-19 in Iranshahr hospitals in April and May 2020 were evaluated (169 patients). The instruments used in this study included a demographic data questionnaire and a checklist to assess the patientchr('39')s clinical condition.

The mean age of patients with COVID-19 was 46 years. The incidence of COVID-19 was slightly higher in men than in women. In patients with COVID-19, a history of hypertension was reported in 24.3%, heart disease in 22.5% and diabetes in 12.4%. Shortness of breath with 71.6% and cough with 69.8% were the most common symptoms and chest pain with 7.7% were the lowest symptoms recorded in patients with COVID-19. 146 people (86.4%) recovered and 34 (13.6%) died.

People with a history of underlying diseases and old age are at high risk of developing COVID-19, so conservative measures and self-quarantine should be performed for these people. In this study, the findings showed that the most obvious symptoms of COVID-19 are shortness of breath and cough, which can be helpful in diagnosing this disease.

COVID-19 infection, which began since 2019 from China, is introduced as a medicinal problem in the world. There is no certain treatment and preventive way actually. In countries that have been successful in controlling the disease, peoplechr('39')s participation has played an important role in controlling the disease. This study was a review on epidemiology, pathophysiology and clinical manifestations of COVID-19 infection in order to guide policy making and promotion of knowledge, attitude and practice of the society associated with COVID-19

This is a review study in which appropriate key words were researched within authentic scientific spaces such as PubMed, Google scholar, CDC, WHO, NEJM and Cell Press from December 2019 till August 2020 and then, subjects were collected and analyzed.

Rapid spread of COVID-19 virus, the relationship between disease severity and mortality with various factors, respiratory transmission, especially in short distance, masks, hand washing and physical distance observance as the most important way to prevent, diversify clinical symptoms and at the same time fever and cough as the most common clinical symptoms, treatment with non-specific antiviral drugs and treatment based on controlling clinical symptoms and strengthening immunity with known drugs, paying attention to children as asymptomatic carriers, and pretentious pregnancy in the event of COVID-19 are the most important findings of this study.

The findings of this study are practical points that awareness of those points is effective in both policy making and promoting the necessary knowledge for COVID-19 infection in the community.

SARS-CoV-2 is the most dangerous virus in the coronavirus family and is a serious warning to all countries in the world. Despite the efforts of researchers, there are widespread ambiguities about it. The aim of this study was to compare the clinical and epidemiological characteristics of deceased and recovered patients with COVID-19.

This descriptive-analytical study was performed in patients with COVID-19 in Vasei Hospital in Sabzevar, Iran in March and April 2020. The tools used were the researcher-made questionnaire, interview and medical files.

From the 178 patients, 52.8% were women and the mean age was 57.1±18 years. 85.4% have recovered and 14% have died. Shortness of breath (72.5%) was the most common symptom, followed by cough (61.8%) and fever (48.9%). 43.8% of all patients and 71.9% of deceased patients had at least one underlying disease. There were significant differences in terms of cough in recovered cases and decreased level of consciousness in deceased patients (P <0.05). Increased white blood cell counts, decreased lymphocytes, and increased neutrophils were significantly higher in deceased patients (P <0.05)

Due to the high rate of infection and death in older people with underlying diseases, precautionary measures should be taken in this group. It is also helpful to pay attention to patientschr('39') symptoms in admission to identify the patientchr('39')s prognosis. An increase in white blood cells and neutrophils and a decrease in lymphocytes indicate that the immune system is involved in these patients. More research is needed to identify the pathogenesis and underlying factors in these patients.

Molar pregnancy is a type of abnormal pregnancy which is divided into complete and partial hydatiform mole. Its incidence varies in different countries and in different regions in every country. Its incidence is higher in Asia than elsewhere in the world, whereas occasionally its risk factors and clinical symptoms are different in various regions. Therefore, this study was performed with aim to evaluate the risk factors and clinical symptoms of hydatiform-mole in pregnant women referred to Ayatollah Rouhani hospital in Babol.

This retrospective descriptive study was performed on all pregnant women of hydatiforme mole with histopathologic definite diagnosis referred to the educational-therapeutic center of Ayatollah Rouhani Hospital in Babol from 2011-2017. Patients' information including demographic and clinical profiles was provided in a checklist format. Data were analyzed by SPSS software (version 18) and Chi-square and one-way ANOVA tests. P<0.05 was considered statistically significant.

In this study during 2011-2017, there were 19145 pregnancies in Babol Rouhani hospital. According to the pathology report, 70 cases of molar pregnancy were recorded. There were 41 (58.6%) of partial hydatidiform mole and 28 (40%) of complete hydatidiform mole. Most patients with molar pregnancy were in the age range of 20-35 years. 31 patients (44.3%) had O blood group. The most common symptom of the patients was bleeding 43 (61.4%).

The incidence of molar pregnancy was high compared with other parts of the world and the prevalence of partial hydatidiform mol was higher than other studies. The risk factors for molar pregnancy were: history of molar pregnancy, and O positive blood group. The most common clinical manifestation of molar pregnancy was bleeding.