The Effect of Eight Weeks of High-intensity Interval Training on Serum Levels of VCAM-1 and E-selectin in Women with Polycystic Ovary Syndrome

Author(s):

Fereshteh Shahidi* , Abbas Ali Gaeini , Marjan Afghan , Roya Hosseini

Message:
Article Type:
Research/Original Article (دارای رتبه معتبر)
Abstract:
Introduction

Women with polycystic ovary syndrome (PCOS) are at increased risk of developing cardiovascular diseases. Exercise is a therapeutic strategy to improve vascular function and reduce patient mortality. Thus, this study aimed to evaluate the effect of eight weeks of high-intensity interval training (HIIT) on serum levels of VCAM-1 and E-selectins in women with PCOS.

Materials and Methods

Thirty females with PCOS aged between 18 and 40 years were randomly categorized into an HIIT group and a control group. The HIIT program was administered three sessions a week for eight weeks. Serum levels of VCAM-1 and E-selectins were measured before and after the intervention after an overnight fast of 10 h. The data were analyzed using SPSS software (version 23).

Results

After the intervention, a significant difference was observed in serum E-selectin levels in the HIIT group (p=0.037) compared to the control group (P>0.05). However, no significant changes were observed in serum VCAM-1 levels in the HIIT group after the intervention (P≥0.05).

Conclusion

The findings demonstrated that eight weeks of HIIT could improve endothelial function in women with PCOS.

Keywords:

PCOS , HIIT , Endothelial function , E-selectin , VCAM-1

Language:
Persian
Published:
Iranian Journal of Endocrinology and Metabolism, Volume:23 Issue: 4, 2022
Pages:
233 to 239
https://magiran.com/p2470086  
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