جستجوی مقالات مرتبط با کلیدواژه "e-selectin" در نشریات گروه "تربیت بدنی"

Increased inflammation caused by obesity is related to vascular health. The present study was conducted with the aim of investigating the effect of aerobic training and caloric restriction on some indicators of vascular inflammation and interleukin 1 in obese male rats.

Twenty-four male rats were randomly divided into four groups: control, exercise, calorie restriction, and exercise + calorie restriction. The aerobic training program was maintained for eight weeks, and the intensity was 24-33 meters per minute with a slope of 15%, and the duration of the training was from 10 minutes on the first day of training to 60 minutes per day, increasing in the fifth week of training and until the end of the program with the same conditions. Restricted groups received 50% of the amount of food consumed by other groups. The concentration of I-selectin, ICAM and interleukin-1 was measured by ELISA method. One-way analysis of variance and Tukey's post hoc test were used at a significance level of 0.05.

The findings showed that aerobic training, calorie restriction and aerobic training with calorie restriction led to a significant decrease in e-selectin (P=0.001), decrease in ICAM (P=0.002) and interleukin-1 (P=0.001).

Eight weeks of aerobic training without and with calorie restriction leads to improvement of some vascular inflammation factors.

Pentraxin-3 and E-selectin glycoproteins are synthesized by endothelium cells, macrophages and myeloid cells during inflammation and play an essential role in heart attack patients. Considering the positive effects of aerobic rehabilitation on heart patients, the present research has investigated the anti-inflammatory response of an aerobic rehabilitation session accompanied by electrical stimulation in rats induced to myocardial infarction.

In this controlled experimental study with a control group, 50 rats (200±30 gram) were randomly divided into 5 groups: healthy, infarcted, infarcted-aerobic rehabilitation, infarcted-electrical stimulation, and infarcted-aerobic rehabilitation-electrical stimulation. Then infarction was induced by subcutaneous injection of Isoproterenol. The intervention groups underwent aerobic rehabilitation (treadmill at a speed of 20 m/min for 1 hour) and electrical stimulation (with foot shock for 0.5 mA and 20 minutes) for one session. Then, immediately after the intervention, the serum levels of the variables were checked by ELISA method. Data analysis was done with one-way ANOVA test and P<0.05 significance.

The results showed that infarct induction led to a significant increase in pentraxin-3 and E-Selectin serum levels in the present study (P=0.0001). Performing rehabilitation and a combination of rehabilitation and electrical stimulation had no significant effect on pentraxin-3 values (P=0.943). But E-selectin concentration was decreased in all groups compared to infarction, and this change was significant in rehabilitation and electrical stimulation group (P=0.044).

It seems that aerobic rehabilitation, electrical stimulation, and a combination of them by reducing E-selectin levels can be effective in improving the condition of myocardial infarction samples by reducing inflammation.

E-selectin reflects endothelial degradation and activation, also plays an important role in inflammatory processes. The aim of this study was to investigate the effects of 8 weeks of high intensity interval resistance training on E-selectin and White blood cell indices in healthy men.twenty four active healthy men were selected and randomly divided into two groups: training (n=11) and control (n=12). Training group was performing high intensity interval resistance training for 8 weeks while control group continued their normal daily life styles. Dependent and independent t-test was used for statistically analyses of variances. Level of significance was p≤0.05.the results showed that 8 weeks of interval resistance exercise decreased significantly level of E-selectin (p=0.001), but differences between control and training groups in monocytes, lymphocytes, basophiles and eosinophils was not significant (p>0.05), also there was significant relation between body weight and E-selectin changes (r=.67, p= 0.001). The results indicate that the high intensity interval resistance training did not result in white blood cells' indices excitation because of enough recovery between sets and repetitions, but E-Selectin were sensitive to exercise pressure and load imposed on body by training and showing higher adaptation to high intensity interval resistance training.

Adhesion moleculs are new indices that have been emphasesed as a communication loops among obesity, sedentary and cardiovascular deaseas. So for the study of the effect of 8 weeks of aerobic training with two forms of continous and HIIT, sedentary overweight volunteear men with age , % BF and weight(24/83±1/83 ,33/58±1/48,91.9±3/66) were randomly divided to two experimental and control groups. The training programs consist for 8 weeks with 65 to 75 %HRmax in a continuous group and interval group preformed 4 set/days with (work) 70 to 95 %HRmax. The blood sampling was preformed after 12 fasting hours in three stages consist of baseline, 48 h after 8 weeks of training and immediately after one session of caute exercise. Resulting data were analyzed by ANOVA with repeated measure 3×3 and post hoc Tukey test (α= 0.05). The finding showed that ICAM1 and E-selectins values in continuous group decreased respectively 3.7 and 6.13 percent significantly and in HIIT group ICAMI decreased as 5.01 percent significantly and E-Selectin decreased 0.3 insignificantly p

cardiovascular disease predictive inflammatory markers are more accurate than lipid profiles in diagnosing diseases. It is important to provide appropriate training pattern in order to reduce the level of inflammatory factors in these patients. The aim of this study was to investigate the effect of 8 weeks of high-intensity interval training on plasma E-selectin levels and white blood cells indices in cardiovascular disease. : Among patients who voluntary referred to Shahid Rjaie cardiovascular, medical and research center for cardiac rehabilitation, 20 patients (male, 50-70yr) were selected and randomly divided into two groups (n=10): High intensity interval training and control. After determining the VO2peak, subjects in HIIT group performed an interval protocol included 8 intervals of 2 min activity (running on treadmill) at 90% of VO2peak and 2 min active recovery at 30% of VO2peak, three session per week for 8 weeks. Whereas control group have not regular exercise training. Before the training and 48 hours after the last training session fasting blood samples were taken. Independent t-test at p<0.05 was used to statistically analysis. The analysis showed significant reduction in E-selectin (p=0.01) and lymphocytes (p=0.01), but there was no significant difference in neutrophils, monocytes and eosinophils responses between two groups (p>0.05). High intensity interval training led to reducing inflammatory factors levels in cardiovascular patients. Probably part of the beneficial effects of high intensity interval training in cardiovascular disease caused by the inflammatory system adaptation and thus reduction the level of inflammatory factors and cytokines with leukocytes origin.

The aim of this study was to investigate the acute effects of continuous or high intensity interval exercise on plasma E-Selectin and WBC indices in CHD patients. Therefore, 30 male heart patients with Coronary Artery Bypass (CABG) and stenting (PCI) history voluntarily participated and divided into three groups: control, continuous and high-intensity interval (HIIT) group. Patients of HIIT group performed 8 repetitions of a 4-min interval training (2:2 min exercise: recovery, intensity: 90:30 %VO2peak), but continuous group performed a 30-min continuous exercise with a constant intensity at 60 %VO2peak. Blood samples were taken before and after exercise and their E-selectin and WBC indices were analyzed. The one-way ANOVA and Pearson correlation were used for statistical analysis. The results showed significant differences between the three groups for E-selectin increase (F2, 27=27.8, P0.05). It can be concluded that a session of exercise may stimulate the inflammation related processes that may be exacerbate in CABG and PCI patients by HIIT. Thus, using this type of exercise for just one session is not recommended in heart patients.